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Dilatation of mesenteric artery

MedGen UID:
1381896
Concept ID:
C4476552
Anatomical Abnormality
Synonym: Mesenteric artery aneurysm
 
HPO: HP:0011934

Definition

Abnormal outpouching or sac-like dilatation in the wall of the inferior mesenteric artery or superior mesenteric artery . [from HPO]

Conditions with this feature

Hereditary hemorrhagic telangiectasia type 4
MedGen UID:
341824
Concept ID:
C1857688
Disease or Syndrome
Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.
Loeys-Dietz syndrome 2
MedGen UID:
382398
Concept ID:
C2674574
Disease or Syndrome
Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, cervical spine malformation and/or instability), craniofacial features (widely spaced eyes, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.
Telangiectasia, hereditary hemorrhagic, type 1
MedGen UID:
1643786
Concept ID:
C4551861
Disease or Syndrome
Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.

Professional guidelines

PubMed

Bannazadeh M, Tadros RO, McKinsey J, Chander R, Marin ML, Faries PL
Surg Technol Int 2016 Apr;28:214-21. PMID: 27175814
Gibbons CP, Roberts DE
Semin Vasc Surg 2010 Mar;23(1):47-53. doi: 10.1053/j.semvascsurg.2009.12.006. PMID: 20298949
Spivack C, Ocken S, Frishman WH
Drugs 1983 Feb;25(2):154-77. doi: 10.2165/00003495-198325020-00004. PMID: 6339198

Recent clinical studies

Etiology

Garzelli L, Ben Abdallah I, Nuzzo A, Zappa M, Corcos O, Dioguardi Burgio M, Cazals-Hatem D, Rautou PE, Vilgrain V, Calame P, Ronot M
Br J Radiol 2023 Nov;96(1151):20230232. Epub 2023 Jul 26 doi: 10.1259/bjr.20230232. PMID: 37493183Free PMC Article
Fei L, Xu M, Wang H, Zhong C, Jiang S, Lichtenberger FB, Erdoğan C, Wang H, Bonk JS, Lai EY, Persson PB, Kovács R, Zheng Z, Patzak A, Khedkar PH
Hypertension 2023 Aug;80(8):1598-1610. Epub 2023 Jun 1 doi: 10.1161/HYPERTENSIONAHA.122.20767. PMID: 37259842
Waheed KB, Shah WJ, Jamal A, Mohammed HR, Altaf B, Amjad M, Bassam MA, Almutawa DH, Arulanantham ZJ
Saudi Med J 2021 Oct;42(10):1145-1148. doi: 10.15537/smj.2021.42.10.20210509. PMID: 34611011Free PMC Article
Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541

Diagnosis

Garzelli L, Ben Abdallah I, Nuzzo A, Zappa M, Corcos O, Dioguardi Burgio M, Cazals-Hatem D, Rautou PE, Vilgrain V, Calame P, Ronot M
Br J Radiol 2023 Nov;96(1151):20230232. Epub 2023 Jul 26 doi: 10.1259/bjr.20230232. PMID: 37493183Free PMC Article
Amir Ali AA, Hameed K, Nawaz A, Khan I, Perveen S
J Coll Physicians Surg Pak 2022 Dec;32(12):SS100-SS101. doi: 10.29271/jcpsp.2022.Supp0.SS100. PMID: 36597304
Waheed KB, Shah WJ, Jamal A, Mohammed HR, Altaf B, Amjad M, Bassam MA, Almutawa DH, Arulanantham ZJ
Saudi Med J 2021 Oct;42(10):1145-1148. doi: 10.15537/smj.2021.42.10.20210509. PMID: 34611011Free PMC Article
Kumar R, Jaiswal G, Bhargava A, Kundu J
Kathmandu Univ Med J (KUMJ) 2016 Jul-Sept.;14(55):288-291. PMID: 28814697
Mohammed AA, Benmousa A, Almeghaiseeb I, Alkarawi M
Hepatogastroenterology 2007 Dec;54(80):2415-20. PMID: 18265678

Therapy

Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Kakehi E, Adachi S, Fukuyasu Y, Hashimoto Y, Yoshida M, Osaka T, Hirotani A, Danbara H, Shimizu K, Fujita R, Kotani K, Matsumura M
Intern Med 2019 Jan 1;58(1):127-133. Epub 2018 Aug 24 doi: 10.2169/internalmedicine.1290-18. PMID: 30146589Free PMC Article
Bannazadeh M, Tadros RO, McKinsey J, Chander R, Marin ML, Faries PL
Surg Technol Int 2016 Apr;28:214-21. PMID: 27175814
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541
Gibbons CP, Roberts DE
Semin Vasc Surg 2010 Mar;23(1):47-53. doi: 10.1053/j.semvascsurg.2009.12.006. PMID: 20298949

Prognosis

Garzelli L, Ben Abdallah I, Nuzzo A, Zappa M, Corcos O, Dioguardi Burgio M, Cazals-Hatem D, Rautou PE, Vilgrain V, Calame P, Ronot M
Br J Radiol 2023 Nov;96(1151):20230232. Epub 2023 Jul 26 doi: 10.1259/bjr.20230232. PMID: 37493183Free PMC Article
Deeg KH
Ultraschall Med 2019 Jun;40(3):292-318. Epub 2019 May 28 doi: 10.1055/a-0879-8110. PMID: 31137054
Millán X, Azzalini L, Dorval JF
Catheter Cardiovasc Interv 2015 Oct;86(4):E194-9. Epub 2015 Jun 29 doi: 10.1002/ccd.25905. PMID: 25712709
Sun Z, Rodriguez J, McMichael J, Walsh RM, Chalikonda S, Rosenthal RJ, Kroh MD, El-Hayek K
Surg Endosc 2015 May;29(5):1137-44. Epub 2015 Feb 21 doi: 10.1007/s00464-014-3775-4. PMID: 25701058
Ravichandran P, Harrington DM, Lovell MB, Harris JR, Derose G, Forbes TL
Vasc Endovascular Surg 2013 Jan;47(1):5-8. Epub 2012 Nov 29 doi: 10.1177/1538574412467863. PMID: 23203595

Clinical prediction guides

Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Oguz A, Uslukaya O, Ülger BV, Turkoglu A, Bahadır MV, Bozdag Z, Böyük A, Göya C
Acta Chir Belg 2016 Apr;116(2):81-8. doi: 10.1080/00015458.2016.1139830. PMID: 27385294
Chen ZL, Zhang XC, Pan GR, Sun Y, Xu M, Li XQ
Ann Vasc Surg 2016 Jan;30:227-35. Epub 2015 Nov 2 doi: 10.1016/j.avsg.2015.07.044. PMID: 26541969
Ravichandran P, Harrington DM, Lovell MB, Harris JR, Derose G, Forbes TL
Vasc Endovascular Surg 2013 Jan;47(1):5-8. Epub 2012 Nov 29 doi: 10.1177/1538574412467863. PMID: 23203595
Ozono Y, Harada T, Namie S, Ichinose H, Shimamine R, Nishimawa Y, Hara K
J Int Med Res 1995 Mar-Apr;23(2):126-31. doi: 10.1177/030006059502300207. PMID: 7601296

Recent systematic reviews

D'Souza RE, Girish G, D'Souza P, Lewis MG, Renjith V
Vasc Endovascular Surg 2022 Apr;56(3):290-297. Epub 2022 Feb 7 doi: 10.1177/15385744211029112. PMID: 35129404
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541

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