U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dilatation of mesenteric artery

MedGen UID:
1381896
Concept ID:
C4476552
Anatomical Abnormality
Synonym: Mesenteric artery aneurysm
 
HPO: HP:0011934

Definition

Abnormal outpouching or sac-like dilatation in the wall of the inferior mesenteric artery or superior mesenteric artery . [from HPO]

Conditions with this feature

Hereditary hemorrhagic telangiectasia type 4
MedGen UID:
341824
Concept ID:
C1857688
Disease or Syndrome
Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.
Loeys-Dietz syndrome 2
MedGen UID:
382398
Concept ID:
C2674574
Disease or Syndrome
Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, cervical spine malformation and/or instability), craniofacial features (widely spaced eyes, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.
Telangiectasia, hereditary hemorrhagic, type 1
MedGen UID:
1643786
Concept ID:
C4551861
Disease or Syndrome
Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.

Professional guidelines

PubMed

Peregrin JH, Kováč J, Prchlík M, Heinige P, Kotanová R, Froňek J, Novotný R, Kočík M, Janoušek L
Cardiovasc Intervent Radiol 2020 May;43(5):765-774. Epub 2020 Feb 10 doi: 10.1007/s00270-020-02430-8. PMID: 32043199
Bannazadeh M, Tadros RO, McKinsey J, Chander R, Marin ML, Faries PL
Surg Technol Int 2016 Apr;28:214-21. PMID: 27175814
Gibbons CP, Roberts DE
Semin Vasc Surg 2010 Mar;23(1):47-53. doi: 10.1053/j.semvascsurg.2009.12.006. PMID: 20298949

Recent clinical studies

Etiology

Nivoit P, Mathivet T, Wu J, Salemkour Y, Sankar DS, Baudrie V, Bourreau J, Guihot AL, Vessieres E, Lemitre M, Bocca C, Teillon J, Le Gall M, Chipont A, Robidel E, Dhaun N, Camerer E, Reynier P, Roux E, Couffinhal T, Hadoke PWF, Silvestre JS, Guillonneau X, Bonnin P, Henrion D, Dengjel J, Tharaux PL, Lenoir O
Cell Mol Life Sci 2023 Jul 18;80(8):210. doi: 10.1007/s00018-023-04859-9. PMID: 37460898Free PMC Article
Waheed KB, Shah WJ, Jamal A, Mohammed HR, Altaf B, Amjad M, Bassam MA, Almutawa DH, Arulanantham ZJ
Saudi Med J 2021 Oct;42(10):1145-1148. doi: 10.15537/smj.2021.42.10.20210509. PMID: 34611011Free PMC Article
Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541
Sato Y, Fukudo S
Clin J Gastroenterol 2015 Oct;8(5):255-63. Epub 2015 Oct 26 doi: 10.1007/s12328-015-0611-x. PMID: 26499370

Diagnosis

Amir Ali AA, Hameed K, Nawaz A, Khan I, Perveen S
J Coll Physicians Surg Pak 2022 Dec;32(12):SS100-SS101. doi: 10.29271/jcpsp.2022.Supp0.SS100. PMID: 36597304
Waheed KB, Shah WJ, Jamal A, Mohammed HR, Altaf B, Amjad M, Bassam MA, Almutawa DH, Arulanantham ZJ
Saudi Med J 2021 Oct;42(10):1145-1148. doi: 10.15537/smj.2021.42.10.20210509. PMID: 34611011Free PMC Article
Kumar R, Jaiswal G, Bhargava A, Kundu J
Kathmandu Univ Med J (KUMJ) 2016 Jul-Sept.;14(55):288-291. PMID: 28814697
Vaglio A, Pipitone N, Salvarani C
Curr Opin Rheumatol 2011 Jan;23(1):1-6. doi: 10.1097/BOR.0b013e328341137d. PMID: 21124080
Mohammed AA, Benmousa A, Almeghaiseeb I, Alkarawi M
Hepatogastroenterology 2007 Dec;54(80):2415-20. PMID: 18265678

Therapy

Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Kakehi E, Adachi S, Fukuyasu Y, Hashimoto Y, Yoshida M, Osaka T, Hirotani A, Danbara H, Shimizu K, Fujita R, Kotani K, Matsumura M
Intern Med 2019 Jan 1;58(1):127-133. Epub 2018 Aug 24 doi: 10.2169/internalmedicine.1290-18. PMID: 30146589Free PMC Article
Bannazadeh M, Tadros RO, McKinsey J, Chander R, Marin ML, Faries PL
Surg Technol Int 2016 Apr;28:214-21. PMID: 27175814
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541
Luan JY, Li X, Li TR, Zhai GJ, Han JT
J Vasc Surg 2013 Jun;57(6):1612-20. Epub 2013 Mar 26 doi: 10.1016/j.jvs.2012.11.121. PMID: 23538008

Prognosis

Ksouri A, Copin P, Bonvalet F, Bozi L, Cazals-Hatem D, Garzelli L, Panis Y, Weiss E, Castier Y, Bouhnik Y, Corcos O, Vilgrain V, Ronot M, Nuzzo A
Eur Radiol 2022 Apr;32(4):2813-2823. Epub 2021 Oct 18 doi: 10.1007/s00330-021-08318-6. PMID: 34657969
Deeg KH
Ultraschall Med 2019 Jun;40(3):292-318. Epub 2019 May 28 doi: 10.1055/a-0879-8110. PMID: 31137054
Ohno-Urabe S, Aoki H, Nishihara M, Furusho A, Hirakata S, Nishida N, Ito S, Hayashi M, Yasukawa H, Imaizumi T, Akashi H, Tanaka H, Fukumoto Y
J Am Heart Assoc 2018 Jan 17;7(2) doi: 10.1161/JAHA.117.007389. PMID: 29343476Free PMC Article
Sirignano P, Setacci F, Galzerano G, Setacci C
Acta Chir Belg 2015 Jul-Aug;115(4):319-21. doi: 10.1080/00015458.2015.11681121. PMID: 26324038
Sun Z, Rodriguez J, McMichael J, Walsh RM, Chalikonda S, Rosenthal RJ, Kroh MD, El-Hayek K
Surg Endosc 2015 May;29(5):1137-44. Epub 2015 Feb 21 doi: 10.1007/s00464-014-3775-4. PMID: 25701058

Clinical prediction guides

Akici M, Cilekar M
Ann Ital Chir 2020;91:35-40. PMID: 32180574
Lap CCMM, Pistorius LR, Mulder EJH, Aliasi M, Kramer WLM, Bilardo CM, Cohen-Overbeek TE, Pajkrt E, Tibboel D, Wijnen RMH, Visser GHA, Manten GTR; FLAMINGO Study Working Group
Ultrasound Obstet Gynecol 2020 Jun;55(6):776-785. doi: 10.1002/uog.21888. PMID: 31613023Free PMC Article
Kapetanios D, Banafsche R, Jerkku T, Spanos K, Hoffmann U, Fiorucci B, Rantner B, Tsilimparis N
J Cardiovasc Surg (Torino) 2019 Apr;60(2):186-190. Epub 2019 Jan 28 doi: 10.23736/S0021-9509.19.10878-6. PMID: 30698372
Ohno-Urabe S, Aoki H, Nishihara M, Furusho A, Hirakata S, Nishida N, Ito S, Hayashi M, Yasukawa H, Imaizumi T, Akashi H, Tanaka H, Fukumoto Y
J Am Heart Assoc 2018 Jan 17;7(2) doi: 10.1161/JAHA.117.007389. PMID: 29343476Free PMC Article
Chen ZL, Zhang XC, Pan GR, Sun Y, Xu M, Li XQ
Ann Vasc Surg 2016 Jan;30:227-35. Epub 2015 Nov 2 doi: 10.1016/j.avsg.2015.07.044. PMID: 26541969

Recent systematic reviews

D'Souza RE, Girish G, D'Souza P, Lewis MG, Renjith V
Vasc Endovascular Surg 2022 Apr;56(3):290-297. Epub 2022 Feb 7 doi: 10.1177/15385744211029112. PMID: 35129404
Norris ML, Harrison ME, Isserlin L, Robinson A, Feder S, Sampson M
Int J Eat Disord 2016 Mar;49(3):216-37. Epub 2015 Sep 26 doi: 10.1002/eat.22462. PMID: 26407541

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...