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Abnormal cardiac atrial physiology

MedGen UID:
1381915
•Concept ID:
C4476779
•
Finding
HPO: HP:0025443

Definition

An abnormality of the function of the cardiac atria. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal cardiac atrial physiology

Professional guidelines

PubMed

Associations of Obstructive Sleep Apnea With Atrial Fibrillation and Continuous Positive Airway Pressure Treatment: A Review.
Linz D, McEvoy RD, Cowie MR, Somers VK, Nattel S, Lévy P, Kalman JM, Sanders P
JAMA Cardiol 2018 Jun 1;3(6):532-540. doi: 10.1001/jamacardio.2018.0095. PMID: 29541763
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.
January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines
J Am Coll Cardiol 2014 Dec 2;64(21):e1-76. Epub 2014 Mar 28 doi: 10.1016/j.jacc.2014.03.022. PMID: 24685669
Atrial fibrillation pathophysiology: implications for management.
Iwasaki YK, Nishida K, Kato T, Nattel S
Circulation 2011 Nov 15;124(20):2264-74. doi: 10.1161/CIRCULATIONAHA.111.019893. PMID: 22083148

Recent clinical studies

Etiology

Atrial Conduction Disorders.
Alexander B, Tse G, Martinez-Selles M, Baranchuk A
Curr Cardiol Rev 2021;17(1):68-73. doi: 10.2174/1573403X17666210112161524. PMID: 33438553Free PMC Article
Cardiac Involvement in Emery-Dreifuss Muscular Dystrophy and Related Management Strategies.
Wang S, Peng D
Int Heart J 2019 Jan 25;60(1):12-18. Epub 2018 Dec 5 doi: 10.1536/ihj.17-604. PMID: 30518714
Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation.
Opacic D, van Bragt KA, Nasrallah HM, Schotten U, Verheule S
Cardiovasc Res 2016 Apr 1;109(4):527-41. Epub 2016 Jan 19 doi: 10.1093/cvr/cvw007. PMID: 26786160
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.
January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines
J Am Coll Cardiol 2014 Dec 2;64(21):e1-76. Epub 2014 Mar 28 doi: 10.1016/j.jacc.2014.03.022. PMID: 24685669
Cardiac arrhythmia diagnosis.
Vukmir RB
Am J Emerg Med 1995 Mar;13(2):204-10. doi: 10.1016/0735-6757(95)90095-0. PMID: 7893310

Diagnosis

Left atrial strain - a current clinical perspective.
Kupczyńska K, Mandoli GE, Cameli M, Kasprzak JD
Kardiol Pol 2021;79(9):955-964. doi: 10.33963/KP.a2021.0105. PMID: 34599503
Atrial functional mitral regurgitation.
Hoit BD
Curr Opin Cardiol 2020 Sep;35(5):474-481. doi: 10.1097/HCO.0000000000000761. PMID: 32649349
Cardiac Involvement in Emery-Dreifuss Muscular Dystrophy and Related Management Strategies.
Wang S, Peng D
Int Heart J 2019 Jan 25;60(1):12-18. Epub 2018 Dec 5 doi: 10.1536/ihj.17-604. PMID: 30518714
Arrhythmias in Patients with Atrial Defects.
Contractor T, Mandapati R
Card Electrophysiol Clin 2017 Jun;9(2):235-244. doi: 10.1016/j.ccep.2017.02.006. PMID: 28457238
Cardiac arrhythmia diagnosis.
Vukmir RB
Am J Emerg Med 1995 Mar;13(2):204-10. doi: 10.1016/0735-6757(95)90095-0. PMID: 7893310

Therapy

Iron and atrial fibrillation: A review.
Ju H, Liu T, Yang M, Cheng M, Wu G
Pacing Clin Electrophysiol 2023 Apr;46(4):312-318. Epub 2023 Mar 7 doi: 10.1111/pace.14678. PMID: 36799332
Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation.
Heijman J, Muna AP, Veleva T, Molina CE, Sutanto H, Tekook M, Wang Q, Abu-Taha IH, Gorka M, Künzel S, El-Armouche A, Reichenspurner H, Kamler M, Nikolaev V, Ravens U, Li N, Nattel S, Wehrens XHT, Dobrev D
Circ Res 2020 Sep 25;127(8):1036-1055. Epub 2020 Jul 30 doi: 10.1161/CIRCRESAHA.120.316710. PMID: 32762493Free PMC Article
Ebstein's Anomaly.
Holst KA, Connolly HM, Dearani JA
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):138-144. doi: 10.14797/mdcj-15-2-138. PMID: 31384377Free PMC Article
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.
January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines
J Am Coll Cardiol 2014 Dec 2;64(21):e1-76. Epub 2014 Mar 28 doi: 10.1016/j.jacc.2014.03.022. PMID: 24685669
Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Whitlock RP, Sun JC, Fremes SE, Rubens FD, Teoh KH
Chest 2012 Feb;141(2 Suppl):e576S-e600S. doi: 10.1378/chest.11-2305. PMID: 22315272Free PMC Article

Prognosis

Left Atrial Myopathy in Heart Failure With Preserved Ejection Fraction.
Omote K, Borlaug BA
Circ J 2023 Jul 25;87(8):1039-1046. Epub 2021 Oct 12 doi: 10.1253/circj.CJ-21-0795. PMID: 34645733
Left atrial strain - a current clinical perspective.
Kupczyńska K, Mandoli GE, Cameli M, Kasprzak JD
Kardiol Pol 2021;79(9):955-964. doi: 10.33963/KP.a2021.0105. PMID: 34599503
Atrial Conduction Disorders.
Alexander B, Tse G, Martinez-Selles M, Baranchuk A
Curr Cardiol Rev 2021;17(1):68-73. doi: 10.2174/1573403X17666210112161524. PMID: 33438553Free PMC Article
Atrial functional mitral regurgitation.
Hoit BD
Curr Opin Cardiol 2020 Sep;35(5):474-481. doi: 10.1097/HCO.0000000000000761. PMID: 32649349
Heart failure in adult congenital heart disease: tetralogy of Fallot.
Mueller AS, McDonald DM, Singh HS, Ginns JN
Heart Fail Rev 2020 Jul;25(4):583-598. doi: 10.1007/s10741-019-09903-0. PMID: 31925611

Clinical prediction guides

Left atrial fibrosis in atrial fibrillation: Mechanisms, clinical evaluation and management.
Ma J, Chen Q, Ma S
J Cell Mol Med 2021 Mar;25(6):2764-2775. Epub 2021 Feb 11 doi: 10.1111/jcmm.16350. PMID: 33576189Free PMC Article
Atrial Conduction Disorders.
Alexander B, Tse G, Martinez-Selles M, Baranchuk A
Curr Cardiol Rev 2021;17(1):68-73. doi: 10.2174/1573403X17666210112161524. PMID: 33438553Free PMC Article
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Left Atrial Appendage: Physiology, Pathology, and Role as a Therapeutic Target.
Regazzoli D, Ancona F, Trevisi N, Guarracini F, Radinovic A, Oppizzi M, Agricola E, Marzi A, Sora NC, Della Bella P, Mazzone P
Biomed Res Int 2015;2015:205013. Epub 2015 Jul 7 doi: 10.1155/2015/205013. PMID: 26236716Free PMC Article
The left atrial appendage: anatomy, function, and noninvasive evaluation.
Beigel R, Wunderlich NC, Ho SY, Arsanjani R, Siegel RJ
JACC Cardiovasc Imaging 2014 Dec;7(12):1251-65. doi: 10.1016/j.jcmg.2014.08.009. PMID: 25496544

Recent systematic reviews

TBX5 variants and cardiac phenotype: A systematic review of the literature and a novel variant.
Møller Nielsen AK, Dehn AM, Hjortdal V, Larsen LA
Eur J Med Genet 2024 Apr;68:104920. Epub 2024 Feb 7 doi: 10.1016/j.ejmg.2024.104920. PMID: 38336121
A systematic review and meta-analysis of the normal reference value of the longitudinal left atrial strain by three dimensional speckle tracking echocardiography.
Mohseni-Badalabadi R, Mirjalili T, Jalali A, Davarpasand T, Hosseinsabet A
Sci Rep 2022 Mar 15;12(1):4395. doi: 10.1038/s41598-022-08379-7. PMID: 35292684Free PMC Article
Electrocardiographic Predictors of Cognitive Decline and Dementia: A Systematic Review.
Imahori Y, Vetrano DL, Ljungman P, Qiu C
J Alzheimers Dis 2021;84(3):1303-1322. doi: 10.3233/JAD-210606. PMID: 34657883
Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis.
Rojas LZ, Glisic M, Pletsch-Borba L, Echeverría LE, Bramer WM, Bano A, Stringa N, Zaciragic A, Kraja B, Asllanaj E, Chowdhury R, Morillo CA, Rueda-Ochoa OL, Franco OH, Muka T
PLoS Negl Trop Dis 2018 Jun;12(6):e0006567. Epub 2018 Jun 13 doi: 10.1371/journal.pntd.0006567. PMID: 29897909Free PMC Article
P-Wave Indices and Risk of Ischemic Stroke: A Systematic Review and Meta-Analysis.
He J, Tse G, Korantzopoulos P, Letsas KP, Ali-Hasan-Al-Saegh S, Kamel H, Li G, Lip GYH, Liu T
Stroke 2017 Aug;48(8):2066-2072. Epub 2017 Jul 5 doi: 10.1161/STROKEAHA.117.017293. PMID: 28679858

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