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Testicular lipomatosis

MedGen UID:
1381947
•Concept ID:
C4477096
•
Anatomical Abnormality
HPO: HP:0025476

Definition

Multiple foci of adipocytes within the testicular interstitium, usually presenting as multiple bilateral ill-defined hyperechoic intratesticular lesions of different sizes but generally with maximum diameter of 4 mm. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular lipomatosis

Professional guidelines

PubMed

Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

Recent clinical studies

Diagnosis

TESTICULAR LIPOMATOSIS IN COWDEN DISEASE.
Khan D, Memon WA, Siddiqui S
J Ayub Med Coll Abbottabad 2015 Oct-Dec;27(4):925-6. PMID: 27004353
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893
Case 175: Testicular lipomatosis in Cowden disease.
Venkatanarasimha N, Hilmy S, Freeman S
Radiology 2011 Nov;261(2):654-8. doi: 10.1148/radiol.11091151. PMID: 22012908
Testicular lipomatosis in Cowden's syndrome.
Woodhouse JB, Delahunt B, English SF, Fraser HH, Ferguson MM
Mod Pathol 2005 Sep;18(9):1151-6. doi: 10.1038/modpathol.3800448. PMID: 15920539

Prognosis

Is Malignant Germ-Cell Tumor Associated With Cowden Syndrome?
Rushin L, Reys B, Freifeld Y, Karpowicz M, Fetzer D, Bagrodia A
Clin Genitourin Cancer 2019 Jun;17(3):e429-e432. Epub 2019 Jan 10 doi: 10.1016/j.clgc.2019.01.002. PMID: 30733184

Recent systematic reviews

Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

Supplemental Content

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    Clinical resources

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    Reviews

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