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Hematologic neoplasm

MedGen UID:: 138213
•Concept ID:: C0376545
•: Neoplastic Process

Synonyms:	Hematologic cancer; Hematological malignancies; Hematological neoplasm
SNOMED CT:	Hematologic neoplasm (129154003); Hematologic malignancy (269475001)

Gene (location): Gene(s) directly associated with this condition or phenotype.	H3C2 (6p22.2)

HPO:	HP:0004377

Definition

Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHematologic neoplasm

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Hematopoietic and Lymphoid System Disorder
        Hematologic disorder
        Hematologic neoplasm
        Bone marrow neoplasm
        Acquired polycythemia vera
        Polycythemia Vera, Polycythemic Phase
        Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase
        Bone marrow cancer
        Erythroid neoplasm
        Megakaryocytic Neoplasm
        Metastatic Malignant Neoplasm in the Bone Marrow
        Myelodysplastic syndrome
        Myelodysplastic/myeloproliferative neoplasm
        Myeloid leukemia
        Myeloproliferative neoplasm
        Therapy related acute myeloid leukemia and myelodysplastic syndrome
        Leukemia
        Acute leukemia
        Acute biphenotypic leukemia
        Acute leukemia of ambiguous lineage
        Acute lymphoid leukemia
        Acute megakaryoblastic leukemia
        Acute monocytic leukemia
        Acute myeloid leukemia
        Acute promyelocytic leukemia
        Burkitt Leukemia
        Recurrent Acute Leukemia
        Refractory Acute Leukemia
        Aleukemic leukemia
        Aleukemic leukemia cutis
        Aleukemic Lymphoid Leukemia
        Bovine Leukoses, Enzootic
        Central nervous system leukemia
        Meningeal Leukemia
        Childhood leukemia
        Childhood acute lymphoblastic leukemia
        Childhood acute myeloid leukemia
        Childhood Burkitt Leukemia
        Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive
        Infant Leukemia
        Chronic leukemia
        Aggressive NK-cell leukemia
        B-cell chronic lymphocytic leukemia
        Chronic eosinophilic leukemia
        Chronic Eosinophilic Leukemia with FIP1L1-PDGFRA
        Chronic myelogenous leukemia, BCR-ABL1 positive
        Chronic neutrophilic leukemia
        Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
        Hairy cell leukemia
        Hairy cell leukemia variant
        Prolymphocytic leukemia
        Recurrent Chronic Leukemia
        Refractory Chronic Leukemia
        T-cell large granular lymphocyte leukemia
        Feline Leukemias
        Leukemia Cutis
        Cutaneous Chronic Lymphocytic Leukemia
        Lymphoid leukemia
        B-Cell Leukemia
        Leukemic Phase of Lymphoma
        Plasma cell leukemia
        Precursor Cell Lymphoblastic Leukemia-Lymphoma
        T cell chronic lymphocytic lymphoma/leukemia
        T-cell leukemia
        Mast cell leukemia
        Acute mast cell leukemia
        Chronic mast cell leukemia
        Myeloproliferative disorder
        Acute myeloid leukemia, M6 type
        Leukemoid reaction
        Myelophthisic anemia
        Primary myelofibrosis
        Thrombocytosis
        Transient myeloproliferative syndrome
        Radiation-Related Leukemia
        Recurrent Leukemia
        Refractory Leukemia
        Splenic manifestation of leukemia
        Splenic Manifestation of Chronic Lymphocytic Leukemia
        Splenic Manifestation of Chronic Myelogenous Leukemia, BCR-ABL1 Positive
        Splenic manifestation of hairy cell leukemia
        Splenic manifestation of prolymphocytic leukemia
        Splenic Manifestation of T-Cell Large Granular Lymphocyte Leukemia
        Testicular leukemia
        Therapy-Related Leukemia
        Chemotherapy-Related Leukemia
        Therapy-Related Acute Myeloid Leukemia
        Lymphoma
        Adult lymphoma
        Adult Hodgkin Lymphoma
        Adult Non-Hodgkin Lymphoma
        Lugano Classification Adult Lymphoma by AJCC v8 Stage
        Advanced Lymphoma
        Advanced Hodgkin Lymphoma
        Advanced Non-Hodgkin Lymphoma
        Alpha-heavy chain disease
        B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma
        Mediastinal gray zone lymphoma
        Recurrent B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma
        Refractory B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma
        Classic Hodgkin lymphoma
        AIDS-Related Hodgkin Lymphoma
        Central Nervous System Hodgkin Lymphoma
        Chest Wall Hodgkin Lymphoma
        Childhood Hodgkin Lymphoma
        Classic Hodgkin Lymphoma
        Classic Hodgkin lymphoma, lymphocyte-rich type
        Classic Hodgkin lymphoma, nodular sclerosis type
        Digestive System Hodgkin Lymphoma
        EBV-Related Hodgkin Lymphoma
        Hodgkin Lymphoma by Ann Arbor Stage
        Hodgkin Lymphoma by Clinical Course
        Hodgkin lymphoma, lymphocyte depletion
        Hodgkin lymphoma, mixed cellularity
        Lugano Classification Hodgkin Lymphoma by AJCC v8 Stage
        Lung Hodgkin Lymphoma
        Mediastinal Hodgkin Lymphoma
        Methotrexate-Associated Hodgkin Lymphoma
        Nodular lymphocyte predominant Hodgkin lymphoma
        Pharyngeal Hodgkin Lymphoma
        Primary Bone Hodgkin Lymphoma
        Primary Cutaneous Hodgkin Lymphoma
        Recurrent Hodgkin Lymphoma
        Refractory Hodgkin Lymphoma
        Salivary Gland Hodgkin Lymphoma
        Secondary Central Nervous System Hodgkin Lymphoma
        Splenic hodgkin lymphoma
        Thyroid Gland Hodgkin Lymphoma
        Composite lymphoma
        Intraocular lymphoma
        Primary Uveal Non-Hodgkin Lymphoma
        Primary Vitreoretinal Non-Hodgkin Lymphoma
        Localized Lymphoma
        Localized Anaplastic Large Cell Lymphoma
        Locally Advanced Lymphoma
        Early Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
        Lymphoma by Site
        Bladder lymphoma
        Breast lymphoma
        Chest wall lymphoma
        Cutaneous Lymphoma
        Eye lymphoma
        Fallopian Tube Lymphoma
        Gastrointestinal lymphoma
        Heart lymphoma
        Kidney Lymphoma
        Lung lymphoma
        Mediastinal malignant lymphoma
        Mucosa-associated lymphoma
        Orbital lymphoma
        Ovarian lymphoma
        Penile Lymphoma
        Pharyngeal Lymphoma
        Pleural Lymphoma
        Primary bone lymphoma
        Primary central nervous system lymphoma
        Prostate lymphoma
        Retroperitoneal lymphoma
        Salivary Gland Lymphoma
        Secondary Central Nervous System Lymphoma
        Secondary Heart Lymphoma
        Sinonasal Lymphoma
        Splenic Lymphoma
        Testicular lymphoma
        Thyroid lymphoma
        Tracheal lymphoma
        Ureteral lymphoma
        Methotrexate-Associated Lymphoma
        Methotrexate-Associated Diffuse Large B-Cell Lymphoma
        Methotrexate-Associated Follicular Lymphoma
        Methotrexate-Associated Peripheral T-Cell Lymphoma
        Non-Hodgkin lymphoma
        AIDS-Related Non-Hodgkin Lymphoma
        B-cell lymphoma
        Breast Non-Hodgkin Lymphoma
        Burkitt lymphoma
        Central nervous system non-hodgkin lymphoma
        Childhood Non-Hodgkin Lymphoma
        Digestive System Non-Hodgkin Lymphoma
        EBV-Related Non-Hodgkin Lymphoma
        Follicular lymphoma
        Helicobacter Pylori-Related Non-Hodgkin Lymphoma
        Large-cell immunoblastic lymphoma
        Lung non-Hodgkin lymphoma
        Lymphoblastic lymphoma
        Lymphoma, non-Hodgkin, familial
        Mediastinal Non-Hodgkin Lymphoma
        Non-Hodgkin Lymphoma by Ann Arbor Stage
        Non-Hodgkin Lymphoma by Clinical Course
        Ocular adnexal lymphoma
        Pharyngeal Non-Hodgkin Lymphoma
        Primary Bone Non-Hodgkin Lymphoma
        Prostate Non-Hodgkin Lymphoma
        Recurrent Non-Hodgkin Lymphoma
        Refractory Non-Hodgkin Lymphoma
        Salivary Gland Non-Hodgkin Lymphoma
        Secondary Central Nervous System Non-Hodgkin Lymphoma
        Secondary Choroidal Non-Hodgkin Lymphoma
        Sinonasal Non-Hodgkin Lymphoma
        Splenic Non-Hodgkin Lymphoma
        T-cell lymphoma
        Thyroid Gland Non-Hodgkin Lymphoma
        Transformed Non-Hodgkin Lymphoma
        Pediatric lymphoma
        Childhood Lymphoma by AJCC v8 Stage
        Recurrent Lymphoma
        Recurrent Breast Lymphoma
        Recurrent Central Nervous System Lymphoma
        Recurrent EBV-Related Lymphoma
        Recurrent Mediastinal Lymphoma
        Recurrent Primary Bone Lymphoma
        Recurrent Primary Cutaneous Lymphoma
        Recurrent Testicular Lymphoma
        Refractory Lymphoma
        Refractory Breast Lymphoma
        Refractory Central Nervous System Lymphoma
        Refractory EBV-Related Lymphoma
        Refractory Mediastinal Lymphoma
        Refractory Primary Bone Lymphoma
        Refractory Primary Cutaneous Lymphoma
        Refractory Testicular Lymphoma
        Unresectable Lymphoma
        Virus-Related Lymphoma
        AIDS-Related Lymphoma
        Diffuse Large B-Cell Lymphoma Arising in HHV8-Positive Multicentric Castleman Disease
        EBV-Related Lymphoma
        HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
        Leukemia-Lymphoma, Adult T-Cell
        Primary effusion lymphoma
        Lymphoproliferative disorder
        Agammaglobulinemia
        Activated PI3K-delta syndrome
        Isolated agammaglobulinemia
        AL amyloidosis
        Primary localized amyloidosis
        Primary systemic amyloidosis
        Recurrent AL Amyloidosis
        Recurrent Primary Amyloidosis
        Refractory AL Amyloidosis
        Refractory Primary Amyloidosis
        Angioimmunoblastic T-cell lymphoma
        Angioimmunoblastic T-Cell Lymphoma by Ann Arbor Stage
        Cutaneous Angioimmunoblastic T-Cell Lymphoma
        Recurrent Angioimmunoblastic T-Cell Lymphoma
        Refractory Angioimmunoblastic T-Cell Lymphoma
        Atypical lymphoproliferative disorder
        Atypical Gastric Lymphoid Hyperplasia
        Castleman disease
        EBV positive mucocutaneous ulcer
        Indolent T-Lymphoblastic Proliferation
        Severe Mosquito Bite Allergy
        Autoimmune lymphoproliferative syndrome
        Autoimmune lymphoproliferative syndrome type 1
        Autoimmune lymphoproliferative syndrome type 4
        Autoimmune lymphoproliferative syndrome type 2A
        Autoimmune lymphoproliferative syndrome type 2B
        Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency
        Autosomal recessive lymphoproliferative disease
        B-Cell Lymphoproliferative Disorder
        Follicular Bronchitis/Bronchiolitis
        Non-Destructive Post-Transplant Lymphoproliferative Disorder
        Benign Lymphoproliferative Disorder
        Chronic lymphoproliferative disorder of NK-cells
        Infectious mononucleosis
        Lymphadenitis
        Lymphocytoma cutis
        Cutaneous Lymphoproliferative Disorder
        Cutaneous Mature B-Cell Neoplasm
        Cutaneous Mature T-Cell and NK-Cell Neoplasm
        Cutaneous Precursor Lymphoid Neoplasm
        Dianzani autoimmune lymphoproliferative disease
        Early-onset autoimmunity-autoinflammation-immunodeficiency syndrome
        Epstein-Barr virus-associated malignant lymphoproliferative disorder
        Diffuse large B-cell lymphoma with chronic inflammation
        EBV-positive T-cell lymphoproliferative disorder of childhood
        EBV-Related Post-Transplant Lymphoproliferative Disorder
        Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly
        Extranodal nasal NK/T cell lymphoma
        HHV8-Positive Germinotropic Lymphoproliferative Disorder
        Hydroa vacciniforme-like lymphoma
        Lymphomatoid granulomatosis
        Plasmablastic lymphoma
        Post-transplant lymphoproliferative disease
        Systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood
        Familial hyperinflammatory lymphoproliferative immunodeficiency
        Granuloma
        Breast granuloma
        Cholesterol granuloma
        Cutaneous granuloma
        Eosinophilic granuloma
        Eosinophilic granulomatosis with polyangiitis
        Foreign body granuloma
        Giant cell granuloma
        Granuloma annulare
        Granuloma by Site
        Granuloma, Respiratory Tract
        Infective granuloma
        Lipogranulomatosis
        Necrobiotic xanthogranuloma
        Necrotizing granulomatous inflammation
        Non-necrotizing granuloma
        Plasma cell granuloma
        Pyogenic granuloma
        Skin epithelioid hemangioma
        Spermatogenic granuloma
        Suppurative Granuloma
        Heavy chain disease
        Gamma heavy chain disease (clinical)
        Mu-heavy chain disease
        HHV8-Related Lymphoproliferative Disorder
        HHV8-Positive Multicentric Castleman Disease
        Lymphangiomyoma
        Lymphangiomyomatosis
        Lymphoid neoplasm
        Neoplastic Post-Transplant Lymphoproliferative Disorder
        Precursor lymphoblastic lymphoma/leukemia
        Recurrent Malignant Lymphoid Neoplasm
        Refractory Malignant Lymphoid Neoplasm
        T-cell and NK-cell neoplasm
        Lymphoproliferative syndrome 1
        Macrophage activation syndrome
        Marek Disease
        Multiple myeloma
        Indolent plasma cell myeloma
        Non-secretory plasma cell myeloma
        Osteosclerotic plasma cell myeloma
        Plasma Cell Myeloma by DS Stage
        Plasma Cell Myeloma by ISS Stage
        Plasma Cell Myeloma by RISS Stage
        Plasma Cell Myeloma Post-Transplant Lymphoproliferative Disorder
        Recurrent Plasma Cell Myeloma
        Refractory Plasma Cell Myeloma
        Smoldering plasma cell myeloma
        Plasmacytoma
        Anaplastic Plasmacytoma
        Extramedullary plasmacytoma
        Extramedullary soft tissue plasmacytoma
        Primary plasmacytoma of the bone
        Solitary osseous plasmacytoma
        Solitary plasmacytoma of chest wall
        Recurrent Lymphoproliferative Disorder
        Recurrent Lymphomatoid Granulomatosis
        Recurrent Polymorphic Post-Transplant Lymphoproliferative Disorder
        Refractory Lymphoproliferative Disorder
        Refractory Polymorphic Post-Transplant Lymphoproliferative Disorder
        Sarcoidosis
        Cardiac sarcoidosis
        Cerebral sarcoidosis
        Hypercalcemic sarcoidosis
        Pulmonary sarcoidosis
        Skin sarcoidosis
        Uveoparotid fever
        Severe combined immunodeficiency due to CARMIL2 deficiency
        Severe combined immunodeficiency due to CD70 deficiency
        Sezary syndrome
        Recurrent Sezary Syndrome
        Refractory Sezary Syndrome
        STAT3-related early-onset multisystem autoimmune disease
        T/NK-Cell Lymphoproliferative Disorder
        Monomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder
        Tumor lysis syndrome
        Waldenstrom macroglobulinemia
        Familial Waldenstrom Macroglobulinemia
        Macroglobulinemia, Waldenstrom, 1
        Macroglobulinemia, Waldenstrom, 2
        Macroglobulinemia, Waldenstrom, somatic
        Recurrent Waldenstrom Macroglobulinemia
        Refractory Waldenstrom Macroglobulinemia
        Smoldering Waldenstrom Macroglobulinemia
        Myelodysplasia
        Bilineage myelodysplasia
        Multiple lineage myelodysplasia
        Single lineage myelodysplasia
        Refractory anemia with ringed sideroblasts (clinical)
        Myeloproliferative disorder, chronic, with eosinophilia

Conditions with this feature

Platelet disorder, undefined

MedGen UID:: 401405
•Concept ID:: C1868258
•: Disease or Syndrome

See: Condition Record

Platelet disorder, undefined

Professional guidelines

PubMed

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Curated

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Therapy

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Best Pract Res Clin Haematol 2022 Jun;35(2):101380. Epub 2022 Sep 14 doi: 10.1016/j.beha.2022.101380. PMID: 36333068

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MedGen

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Hematologic neoplasm

Definition

Term Hierarchy

Conditions with this feature

Professional guidelines

PubMed

Curated

Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Genetic Testing Registry

Clinical resources

Practice guidelines

Curated

Molecular resources

Consumer resources

Reviews

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