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Unresectable Liposarcoma

MedGen UID:
1383212
•Concept ID:
C4331476
•
Neoplastic Process

Definition

A liposarcoma which is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Liposarcoma

Professional guidelines

PubMed

Efficacy of trabectedin for the treatment of liposarcoma.
Zijoo R, von Mehren M
Expert Opin Pharmacother 2016 Oct;17(14):1953-62. Epub 2016 Sep 15 doi: 10.1080/14656566.2016.1229304. PMID: 27615729

Recent clinical studies

Etiology

Adjuvant Palbociclib May be Associated with Delayed Recurrence in Completely Resected Retroperitoneal Liposarcoma: Results of a Single-Institution Retrospective Cohort Study.
Selby LV, Clark EC, Liebner DA, Chen JL, Tinoco G, Bashian E, Beane JD, Pollock RE, Grignol VP
Ann Surg Oncol 2023 Nov;30(12):7876-7881. Epub 2023 Jun 17 doi: 10.1245/s10434-023-13692-0. PMID: 37330448

Therapy

Complete Response to Eribulin in a Patient with Unresectable Liposarcoma: A Case Report and Implications of New Biomarkers.
Nakamura H, Takada K, Emori M, Hayasaka N, Sugita S
Intern Med 2022 Dec 1;61(23):3617-3621. Epub 2022 May 7 doi: 10.2169/internalmedicine.9423-22. PMID: 35527027Free PMC Article
Efficacy of trabectedin for the treatment of liposarcoma.
Zijoo R, von Mehren M
Expert Opin Pharmacother 2016 Oct;17(14):1953-62. Epub 2016 Sep 15 doi: 10.1080/14656566.2016.1229304. PMID: 27615729
Medical management of unresectable, recurrent low-grade retroperitoneal liposarcoma: integration of cytotoxic and non-cytotoxic therapies into multimodality care.
Goss G, Demetri G
Surg Oncol 2000 Aug;9(2):53-9. doi: 10.1016/s0960-7404(00)00023-2. PMID: 11094323

Prognosis

Medical management of unresectable, recurrent low-grade retroperitoneal liposarcoma: integration of cytotoxic and non-cytotoxic therapies into multimodality care.
Goss G, Demetri G
Surg Oncol 2000 Aug;9(2):53-9. doi: 10.1016/s0960-7404(00)00023-2. PMID: 11094323

Clinical prediction guides

Adjuvant Palbociclib May be Associated with Delayed Recurrence in Completely Resected Retroperitoneal Liposarcoma: Results of a Single-Institution Retrospective Cohort Study.
Selby LV, Clark EC, Liebner DA, Chen JL, Tinoco G, Bashian E, Beane JD, Pollock RE, Grignol VP
Ann Surg Oncol 2023 Nov;30(12):7876-7881. Epub 2023 Jun 17 doi: 10.1245/s10434-023-13692-0. PMID: 37330448
Complete Response to Eribulin in a Patient with Unresectable Liposarcoma: A Case Report and Implications of New Biomarkers.
Nakamura H, Takada K, Emori M, Hayasaka N, Sugita S
Intern Med 2022 Dec 1;61(23):3617-3621. Epub 2022 May 7 doi: 10.2169/internalmedicine.9423-22. PMID: 35527027Free PMC Article

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