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B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

MedGen UID:
1384106
Concept ID:
C4329381
Neoplastic Process
Synonyms: B Acute Lymphoblastic Leukemia with Translocations Involving Tyrosine Kinases or Cytokine Receptors; B-ALL with Translocations Involving Tyrosine Kinases or Cytokine Receptors; B-Cell Acute Lymphoblastic Leukemia, BCR-ABL1-Like

Definition

B acute lymphoblastic leukemia with translocations involving tyrosine kinases, or translocations involving either the cytokine receptor-like factor 2 (CRLF2) or rearrangements leading to truncation and activation of the erythropoietin receptor (EPOR). It is associated with an adverse prognosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVB Acute Lymphoblastic Leukemia, BCR-ABL1-Like

Professional guidelines

PubMed

Zhang L, Shah B, Zhang Y, Tashkandi H, Xiao W, Fernandez-Pol S, Vergara-Lluri M, Hussaini M, Song J, Lancet J, Moscinski L, Yun S, Lu CM, Medeiros LJ, Tang G
Hum Pathol 2023 Jun;136:1-15. Epub 2023 Mar 22 doi: 10.1016/j.humpath.2023.03.002. PMID: 36958463
Anagnostou T, Knudson RA, Pearce KE, Meyer RG, Pitel BA, Peterson JF, Baughn LB, Reichard KK, Ketterling RP, Kloft-Nelson SM, Knutson DL, Khan SP, Gangat N, Litzow MR, Hogan WJ, Wolanskyj A, Al-Kali A, Begna KH, Elliott M, Pardanani A, Foran J, Shah M, Tefferi A, Alkhateeb H, Halling K, Rodriguez V, Greipp PT, Patnaik MM
Am J Hematol 2020 Mar;95(3):E68-E72. Epub 2020 Jan 26 doi: 10.1002/ajh.25729. PMID: 31919873

Recent clinical studies

Etiology

Davis K, Sheikh T, Aggarwal N
Semin Diagn Pathol 2023 May;40(3):202-215. Epub 2023 Apr 9 doi: 10.1053/j.semdp.2023.04.003. PMID: 37120350
Płotka A, Lewandowski K
Acta Haematol 2022;145(2):122-131. Epub 2021 Nov 24 doi: 10.1159/000519782. PMID: 34818644
Chiaretti S, Messina M, Della Starza I, Piciocchi A, Cafforio L, Cavalli M, Taherinasab A, Ansuinelli M, Elia L, Albertini Petroni G, La Starza R, Canichella M, Lauretti A, Puzzolo MC, Pierini V, Santoro A, Spinelli O, Apicella V, Capria S, Di Raimondo F, De Fabritiis P, Papayannidis C, Candoni A, Cairoli R, Cerrano M, Fracchiolla N, Mattei D, Cattaneo C, Vitale A, Crea E, Fazi P, Mecucci C, Rambaldi A, Guarini A, Bassan R, Foà R
Haematologica 2021 Jun 1;106(6):1559-1568. doi: 10.3324/haematol.2020.247973. PMID: 32467145Free PMC Article
Conant JL, Czuchlewski DR
Int J Lab Hematol 2019 May;41 Suppl 1:126-130. doi: 10.1111/ijlh.13012. PMID: 31069976
Roberts KG
Best Pract Res Clin Haematol 2018 Dec;31(4):351-356. Epub 2018 Sep 20 doi: 10.1016/j.beha.2018.09.003. PMID: 30466746

Diagnosis

Davis K, Sheikh T, Aggarwal N
Semin Diagn Pathol 2023 May;40(3):202-215. Epub 2023 Apr 9 doi: 10.1053/j.semdp.2023.04.003. PMID: 37120350
Płotka A, Lewandowski K
Acta Haematol 2022;145(2):122-131. Epub 2021 Nov 24 doi: 10.1159/000519782. PMID: 34818644
Chiaretti S, Messina M, Della Starza I, Piciocchi A, Cafforio L, Cavalli M, Taherinasab A, Ansuinelli M, Elia L, Albertini Petroni G, La Starza R, Canichella M, Lauretti A, Puzzolo MC, Pierini V, Santoro A, Spinelli O, Apicella V, Capria S, Di Raimondo F, De Fabritiis P, Papayannidis C, Candoni A, Cairoli R, Cerrano M, Fracchiolla N, Mattei D, Cattaneo C, Vitale A, Crea E, Fazi P, Mecucci C, Rambaldi A, Guarini A, Bassan R, Foà R
Haematologica 2021 Jun 1;106(6):1559-1568. doi: 10.3324/haematol.2020.247973. PMID: 32467145Free PMC Article
Jain S, Abraham A
Arch Pathol Lab Med 2020 Feb;144(2):150-155. Epub 2019 Oct 23 doi: 10.5858/arpa.2019-0194-RA. PMID: 31644323
Chiaretti S, Messina M, Foà R
Cancer 2019 Jan 15;125(2):194-204. Epub 2018 Dec 18 doi: 10.1002/cncr.31848. PMID: 30561755

Therapy

Iacobucci I, Roberts KG
Genes (Basel) 2021 May 1;12(5) doi: 10.3390/genes12050687. PMID: 34062932Free PMC Article
Chiaretti S, Messina M, Foà R
Cancer 2019 Jan 15;125(2):194-204. Epub 2018 Dec 18 doi: 10.1002/cncr.31848. PMID: 30561755
Roberts KG
Best Pract Res Clin Haematol 2018 Dec;31(4):351-356. Epub 2018 Sep 20 doi: 10.1016/j.beha.2018.09.003. PMID: 30466746
Wells J, Jain N, Konopleva M
Clin Adv Hematol Oncol 2017 Jul;15(7):554-561. PMID: 28749919
Boer JM, den Boer ML
Eur J Cancer 2017 Sep;82:203-218. Epub 2017 Jul 12 doi: 10.1016/j.ejca.2017.06.012. PMID: 28709134

Prognosis

Jeha S, Choi J, Roberts KG, Pei D, Coustan-Smith E, Inaba H, Rubnitz JE, Ribeiro RC, Gruber TA, Raimondi SC, Karol SE, Qu C, Brady SW, Gu Z, Yang JJ, Cheng C, Downing JR, Evans WE, Relling MV, Campana D, Mullighan CG, Pui CH
Blood Cancer Discov 2021 Jul;2(4):326-337. doi: 10.1158/2643-3230.BCD-20-0229. PMID: 34250504Free PMC Article
Chiaretti S, Messina M, Della Starza I, Piciocchi A, Cafforio L, Cavalli M, Taherinasab A, Ansuinelli M, Elia L, Albertini Petroni G, La Starza R, Canichella M, Lauretti A, Puzzolo MC, Pierini V, Santoro A, Spinelli O, Apicella V, Capria S, Di Raimondo F, De Fabritiis P, Papayannidis C, Candoni A, Cairoli R, Cerrano M, Fracchiolla N, Mattei D, Cattaneo C, Vitale A, Crea E, Fazi P, Mecucci C, Rambaldi A, Guarini A, Bassan R, Foà R
Haematologica 2021 Jun 1;106(6):1559-1568. doi: 10.3324/haematol.2020.247973. PMID: 32467145Free PMC Article
Conant JL, Czuchlewski DR
Int J Lab Hematol 2019 May;41 Suppl 1:126-130. doi: 10.1111/ijlh.13012. PMID: 31069976
Chiaretti S, Messina M, Foà R
Cancer 2019 Jan 15;125(2):194-204. Epub 2018 Dec 18 doi: 10.1002/cncr.31848. PMID: 30561755
Herold T, Gökbuget N
Curr Oncol Rep 2017 May;19(5):31. doi: 10.1007/s11912-017-0589-2. PMID: 28361222

Clinical prediction guides

Kaumeyer B, Fidai S, Sukhanova M, Yap KL, Segal J, Raca G, Stock W, McNeer J, Lager AM, Gurbuxani S
Leuk Lymphoma 2022 Jun;63(6):1436-1444. Epub 2022 Feb 16 doi: 10.1080/10428194.2022.2025797. PMID: 35171727
Aldoss I, Advani AS
Best Pract Res Clin Haematol 2021 Mar;34(1):101242. Epub 2021 Jan 11 doi: 10.1016/j.beha.2021.101242. PMID: 33762097
Hrabovsky S, Vrzalova Z, Stika J, Jelinkova H, Jarosova M, Navrkalova V, Martenek J, Folber F, Salek C, Horacek JM, Pospisilova S, Mayer J, Doubek M
Acta Oncol 2021 Jun;60(6):760-770. Epub 2021 Mar 22 doi: 10.1080/0284186X.2021.1900908. PMID: 33750258
Chiaretti S, Messina M, Della Starza I, Piciocchi A, Cafforio L, Cavalli M, Taherinasab A, Ansuinelli M, Elia L, Albertini Petroni G, La Starza R, Canichella M, Lauretti A, Puzzolo MC, Pierini V, Santoro A, Spinelli O, Apicella V, Capria S, Di Raimondo F, De Fabritiis P, Papayannidis C, Candoni A, Cairoli R, Cerrano M, Fracchiolla N, Mattei D, Cattaneo C, Vitale A, Crea E, Fazi P, Mecucci C, Rambaldi A, Guarini A, Bassan R, Foà R
Haematologica 2021 Jun 1;106(6):1559-1568. doi: 10.3324/haematol.2020.247973. PMID: 32467145Free PMC Article
Chiaretti S, Messina M, Grammatico S, Piciocchi A, Fedullo AL, Di Giacomo F, Peragine N, Gianfelici V, Lauretti A, Bareja R, Martelli MP, Vignetti M, Apicella V, Vitale A, Li LS, Salek C, Elemento O, Inghirami G, Weinstock DM, Guarini A, Foà R
Br J Haematol 2018 Jun;181(5):642-652. Epub 2018 Apr 19 doi: 10.1111/bjh.15251. PMID: 29675955Free PMC Article

Recent systematic reviews

Owattanapanich W, Rujirachun P, Ungprasert P, Buaboonnam J, Techavichit P
Clin Lymphoma Myeloma Leuk 2020 Jan;20(1):e22-e29. Epub 2019 Aug 27 doi: 10.1016/j.clml.2019.08.003. PMID: 31699654

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