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Abnormal circulating thyroglobulin level

MedGen UID:
1384239
Concept ID:
C4476804
Finding
HPO: HP:0025483

Definition

A deviation from the normal concentration of thyroglobulin, a protein produced in the thyroid gland that acts as a precursor to thyrroid hormones. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating thyroglobulin level

Recent clinical studies

Etiology

Zhao J, Chen Y, Zhao Q, Shi J, Yang W, Zhu Z, Yu W, Guan J, Song Y, Wu H, Jin W, Zhou Y, Liu J
Autoimmunity 2018 Nov;51(7):352-359. Epub 2018 Oct 20 doi: 10.1080/08916934.2018.1516761. PMID: 30345813
Onal ED, Saglam F, Sacikara M, Ersoy R, Cakir B
Arq Bras Endocrinol Metabol 2014 Feb;58(1):48-52. doi: 10.1590/0004-2730000002846. PMID: 24728164
Colao A, Pivonello R, Faggiano A, Filippella M, Ferone D, Di Somma C, Cerbone G, Marzullo P, Fenzi G, Lombardi G
Clin Endocrinol (Oxf) 2000 Jul;53(1):13-9. doi: 10.1046/j.1365-2265.2000.01018.x. PMID: 10931076
Esplin MS, Branch DW, Silver R, Stagnaro-Green A
Am J Obstet Gynecol 1998 Dec;179(6 Pt 1):1583-6. doi: 10.1016/s0002-9378(98)70029-8. PMID: 9855601
Preus M, Frecker MF, Stenszky V, Balaźs C, Farid NR
Clin Endocrinol (Oxf) 1985 Dec;23(6):653-61. doi: 10.1111/j.1365-2265.1985.tb01126.x. PMID: 3841651

Diagnosis

Onal ED, Saglam F, Sacikara M, Ersoy R, Cakir B
Arq Bras Endocrinol Metabol 2014 Feb;58(1):48-52. doi: 10.1590/0004-2730000002846. PMID: 24728164
Milas M, Mazzaglia P, Chia SY, Skugor M, Berber E, Reddy S, Gupta M, Siperstein A
Surgery 2007 Feb;141(2):137-46; discussion 146. doi: 10.1016/j.surg.2006.12.002. PMID: 17263967
Colao A, Pivonello R, Faggiano A, Filippella M, Ferone D, Di Somma C, Cerbone G, Marzullo P, Fenzi G, Lombardi G
Clin Endocrinol (Oxf) 2000 Jul;53(1):13-9. doi: 10.1046/j.1365-2265.2000.01018.x. PMID: 10931076
Preus M, Frecker MF, Stenszky V, Balaźs C, Farid NR
Clin Endocrinol (Oxf) 1985 Dec;23(6):653-61. doi: 10.1111/j.1365-2265.1985.tb01126.x. PMID: 3841651
Gons MH, Kok JH, Tegelaers WH, de Vijlder JJ
Acta Endocrinol (Copenh) 1983 Sep;104(1):27-34. doi: 10.1530/acta.0.1040027. PMID: 6624362

Therapy

Braverman LE
Thyroid 2007 Sep;17(9):819-22. doi: 10.1089/thy.2007.0105. PMID: 17705696
Mainwaring RD, Capparelli E, Schell K, Acosta M, Nelson JC
Circulation 2000 Mar 28;101(12):1423-9. doi: 10.1161/01.cir.101.12.1423. PMID: 10736287
Cappiello E, Boldorini R, Tosoni A, Piraneo S, Bernasconi R, Raggi U
J Endocrinol Invest 1995 Dec;18(11):862-8. doi: 10.1007/BF03349834. PMID: 8778159
Silva JE, Santelices R, Kishihara M, Schneider A
J Clin Endocrinol Metab 1984 Mar;58(3):526-34. doi: 10.1210/jcem-58-3-526. PMID: 6693549
Marcocci C, Chiovato L, Mariotti S, Pinchera A
J Endocrinol Invest 1982 Jan-Feb;5(1):13-9. doi: 10.1007/BF03350476. PMID: 6896520

Prognosis

Chen J, Tian J, Tang X, Rui K, Ma J, Mao C, Liu Y, Lu L, Xu H, Wang S
Endocrine 2015 Aug;49(3):752-60. Epub 2015 Feb 11 doi: 10.1007/s12020-015-0546-5. PMID: 25666935
Colao A, Pivonello R, Faggiano A, Filippella M, Ferone D, Di Somma C, Cerbone G, Marzullo P, Fenzi G, Lombardi G
Clin Endocrinol (Oxf) 2000 Jul;53(1):13-9. doi: 10.1046/j.1365-2265.2000.01018.x. PMID: 10931076
Cappiello E, Boldorini R, Tosoni A, Piraneo S, Bernasconi R, Raggi U
J Endocrinol Invest 1995 Dec;18(11):862-8. doi: 10.1007/BF03349834. PMID: 8778159
Martin A, Valentine M, Unger P, Lichtenstein C, Schwartz AE, Friedman EW, Shultz LD, Davies TF
J Clin Endocrinol Metab 1993 Aug;77(2):305-10. doi: 10.1210/jcem.77.2.8345031. PMID: 8345031
Preus M, Frecker MF, Stenszky V, Balaźs C, Farid NR
Clin Endocrinol (Oxf) 1985 Dec;23(6):653-61. doi: 10.1111/j.1365-2265.1985.tb01126.x. PMID: 3841651

Clinical prediction guides

Matana A, Ziros PG, Chartoumpekis DV, Renaud CO, Polašek O, Hayward C, Zemunik T, Sykiotis GP
Biochem Pharmacol 2020 Mar;173:113605. Epub 2019 Aug 14 doi: 10.1016/j.bcp.2019.08.007. PMID: 31421134
Chen J, Tian J, Tang X, Rui K, Ma J, Mao C, Liu Y, Lu L, Xu H, Wang S
Endocrine 2015 Aug;49(3):752-60. Epub 2015 Feb 11 doi: 10.1007/s12020-015-0546-5. PMID: 25666935
Onal ED, Saglam F, Sacikara M, Ersoy R, Cakir B
Arq Bras Endocrinol Metabol 2014 Feb;58(1):48-52. doi: 10.1590/0004-2730000002846. PMID: 24728164
Braverman LE
Thyroid 2007 Sep;17(9):819-22. doi: 10.1089/thy.2007.0105. PMID: 17705696
Preus M, Frecker MF, Stenszky V, Balaźs C, Farid NR
Clin Endocrinol (Oxf) 1985 Dec;23(6):653-61. doi: 10.1111/j.1365-2265.1985.tb01126.x. PMID: 3841651

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