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Hyperpigmented papule

MedGen UID:
1386336
•Concept ID:
C3647115
•
Finding
HPO: HP:0025473

Definition

A papule (circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point) that exhibits increased pigmentation (is darker) compared to the surrounding skin. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperpigmented papule

Professional guidelines

PubMed

Efficacy of 1064-nm Nd:YAG picosecond laser in lichen amyloidosis treatment: clinical and dermoscopic evaluation.
Lueangarun S, Tempark T
J Cosmet Laser Ther 2021 May 19;23(3-4):55-58. Epub 2021 Sep 8 doi: 10.1080/14764172.2021.1975756. PMID: 34493149
Treatment of dermatosis papulosa nigra using a carbon dioxide laser.
Furukawa F, Mizawa M, Shimizu T
J Cosmet Dermatol 2020 Oct;19(10):2572-2575. Epub 2020 Jan 28 doi: 10.1111/jocd.13309. PMID: 31990432
Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. PMID: 30465511Free PMC Article

Recent clinical studies

Etiology

Can granuloma annulare evolve into cutaneous sarcoidosis?
Lupton JR, Figueroa P, Berberian BJ, Sulica VI
Cutis 2000 Nov;66(5):390-2. PMID: 11107527

Diagnosis

Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848
Pyoderma gangrenosum in association with microscopic colitis, idiopathic hypereosinophilic syndrome, selective IgE deficiency and diabetes mellitus.
Riyaz N, Sasidharanpillai S, Rahima S, Bindu V, Shaan M, Raghavan NT, Mohan L, Janardhanan AK
Clin Exp Dermatol 2015 Aug;40(6):629-32. Epub 2015 Feb 22 doi: 10.1111/ced.12618. PMID: 25704069

Therapy

Diltiazem-induced hyperpigmentation.
Kuykendall-Ivy T, Collier SL, Johnson SM
Cutis 2004 Apr;73(4):239-40. PMID: 15134323
Can granuloma annulare evolve into cutaneous sarcoidosis?
Lupton JR, Figueroa P, Berberian BJ, Sulica VI
Cutis 2000 Nov;66(5):390-2. PMID: 11107527

Prognosis

Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848
Can granuloma annulare evolve into cutaneous sarcoidosis?
Lupton JR, Figueroa P, Berberian BJ, Sulica VI
Cutis 2000 Nov;66(5):390-2. PMID: 11107527

Clinical prediction guides

Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848

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