U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Childhood T Acute Lymphoblastic Leukemia

MedGen UID:
1388290
Concept ID:
C4331224
Neoplastic Process
Synonym: Recurrent Childhood T-Acute Lymphoblastic Leukemia

Definition

The reemergence of T-acute lymphoblastic leukemia in childhood after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood T Acute Lymphoblastic Leukemia

Professional guidelines

PubMed

Graiqevci-Uka V, Behluli E, Spahiu L, Liehr T, Temaj G
Curr Pediatr Rev 2023;19(2):150-156. doi: 10.2174/1573396318666220901165247. PMID: 36056858Free PMC Article
Grunenberg A, Sala E, Kapp-Schwoerer S, Viardot A
Expert Opin Pharmacother 2022 Apr;23(5):561-571. Epub 2022 Feb 22 doi: 10.1080/14656566.2022.2033725. PMID: 35193450
Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, van der Velden V, Stary J, Zuna J, Escherich G, Stadt UZ, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A
Haematologica 2018 Jan;103(1):107-115. Epub 2017 Oct 27 doi: 10.3324/haematol.2017.176917. PMID: 29079599Free PMC Article

Recent clinical studies

Etiology

Pan J, Tang K, Luo Y, Seery S, Tan Y, Deng B, Liu F, Xu X, Ling Z, Song W, Xu J, Duan J, Wang Z, Li C, Wang K, Zhang Y, Yu X, Zheng Q, Zhao L, Zhang J, Chang AH, Feng X
Lancet Oncol 2023 Nov;24(11):1229-1241. Epub 2023 Oct 17 doi: 10.1016/S1470-2045(23)00436-9. PMID: 37863088
Chiesa R, Georgiadis C, Syed F, Zhan H, Etuk A, Gkazi SA, Preece R, Ottaviano G, Braybrook T, Chu J, Kubat A, Adams S, Thomas R, Gilmour K, O'Connor D, Vora A, Qasim W; Base-Edited CAR T Group
N Engl J Med 2023 Sep 7;389(10):899-910. Epub 2023 Jun 14 doi: 10.1056/NEJMoa2300709. PMID: 37314354
Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Brown PA, Ji L, Xu X, Devidas M, Hogan LE, Borowitz MJ, Raetz EA, Zugmaier G, Sharon E, Bernhardt MB, Terezakis SA, Gore L, Whitlock JA, Pulsipher MA, Hunger SP, Loh ML
JAMA 2021 Mar 2;325(9):833-842. doi: 10.1001/jama.2021.0669. PMID: 33651090Free PMC Article
Liu Y, Easton J, Shao Y, Maciaszek J, Wang Z, Wilkinson MR, McCastlain K, Edmonson M, Pounds SB, Shi L, Zhou X, Ma X, Sioson E, Li Y, Rusch M, Gupta P, Pei D, Cheng C, Smith MA, Auvil JG, Gerhard DS, Relling MV, Winick NJ, Carroll AJ, Heerema NA, Raetz E, Devidas M, Willman CL, Harvey RC, Carroll WL, Dunsmore KP, Winter SS, Wood BL, Sorrentino BP, Downing JR, Loh ML, Hunger SP, Zhang J, Mullighan CG
Nat Genet 2017 Aug;49(8):1211-1218. Epub 2017 Jul 3 doi: 10.1038/ng.3909. PMID: 28671688Free PMC Article

Diagnosis

Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772
Mroczek A, Zawitkowska J, Kowalczyk J, Lejman M
Int J Mol Sci 2021 Jan 15;22(2) doi: 10.3390/ijms22020808. PMID: 33467425Free PMC Article
Burkhardt B, Hermiston ML
Br J Haematol 2019 Jun;185(6):1158-1170. Epub 2019 Feb 27 doi: 10.1111/bjh.15793. PMID: 30809797
Health Quality Ontario
Ont Health Technol Assess Ser 2016;16(7):1-52. Epub 2016 Mar 8 PMID: 27099643Free PMC Article

Therapy

Pan J, Tang K, Luo Y, Seery S, Tan Y, Deng B, Liu F, Xu X, Ling Z, Song W, Xu J, Duan J, Wang Z, Li C, Wang K, Zhang Y, Yu X, Zheng Q, Zhao L, Zhang J, Chang AH, Feng X
Lancet Oncol 2023 Nov;24(11):1229-1241. Epub 2023 Oct 17 doi: 10.1016/S1470-2045(23)00436-9. PMID: 37863088
Chiesa R, Georgiadis C, Syed F, Zhan H, Etuk A, Gkazi SA, Preece R, Ottaviano G, Braybrook T, Chu J, Kubat A, Adams S, Thomas R, Gilmour K, O'Connor D, Vora A, Qasim W; Base-Edited CAR T Group
N Engl J Med 2023 Sep 7;389(10):899-910. Epub 2023 Jun 14 doi: 10.1056/NEJMoa2300709. PMID: 37314354
Laetsch TW, Maude SL, Rives S, Hiramatsu H, Bittencourt H, Bader P, Baruchel A, Boyer M, De Moerloose B, Qayed M, Buechner J, Pulsipher MA, Myers GD, Stefanski HE, Martin PL, Nemecek E, Peters C, Yanik G, Khaw SL, Davis KL, Krueger J, Balduzzi A, Boissel N, Tiwari R, O'Donovan D, Grupp SA
J Clin Oncol 2023 Mar 20;41(9):1664-1669. Epub 2022 Nov 18 doi: 10.1200/JCO.22.00642. PMID: 36399695Free PMC Article
Lato MW, Przysucha A, Grosman S, Zawitkowska J, Lejman M
Int J Mol Sci 2021 Apr 26;22(9) doi: 10.3390/ijms22094502. PMID: 33925883Free PMC Article
Brown PA, Ji L, Xu X, Devidas M, Hogan LE, Borowitz MJ, Raetz EA, Zugmaier G, Sharon E, Bernhardt MB, Terezakis SA, Gore L, Whitlock JA, Pulsipher MA, Hunger SP, Loh ML
JAMA 2021 Mar 2;325(9):833-842. doi: 10.1001/jama.2021.0669. PMID: 33651090Free PMC Article

Prognosis

Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772
Lato MW, Przysucha A, Grosman S, Zawitkowska J, Lejman M
Int J Mol Sci 2021 Apr 26;22(9) doi: 10.3390/ijms22094502. PMID: 33925883Free PMC Article
Brown PA, Ji L, Xu X, Devidas M, Hogan LE, Borowitz MJ, Raetz EA, Zugmaier G, Sharon E, Bernhardt MB, Terezakis SA, Gore L, Whitlock JA, Pulsipher MA, Hunger SP, Loh ML
JAMA 2021 Mar 2;325(9):833-842. doi: 10.1001/jama.2021.0669. PMID: 33651090Free PMC Article
Burkhardt B, Hermiston ML
Br J Haematol 2019 Jun;185(6):1158-1170. Epub 2019 Feb 27 doi: 10.1111/bjh.15793. PMID: 30809797

Clinical prediction guides

Pan J, Tang K, Luo Y, Seery S, Tan Y, Deng B, Liu F, Xu X, Ling Z, Song W, Xu J, Duan J, Wang Z, Li C, Wang K, Zhang Y, Yu X, Zheng Q, Zhao L, Zhang J, Chang AH, Feng X
Lancet Oncol 2023 Nov;24(11):1229-1241. Epub 2023 Oct 17 doi: 10.1016/S1470-2045(23)00436-9. PMID: 37863088
Pulsipher MA, Han X, Maude SL, Laetsch TW, Qayed M, Rives S, Boyer MW, Hiramatsu H, Yanik GA, Driscoll T, Myers GD, Bader P, Baruchel A, Buechner J, Stefanski HE, Kalfoglou C, Nguyen K, Waldron ER, Thudium Mueller K, Maier HJ, Kari G, Grupp SA
Blood Cancer Discov 2022 Jan;3(1):66-81. Epub 2021 Dec 1 doi: 10.1158/2643-3230.BCD-21-0095. PMID: 35019853Free PMC Article
Mroczek A, Zawitkowska J, Kowalczyk J, Lejman M
Int J Mol Sci 2021 Jan 15;22(2) doi: 10.3390/ijms22020808. PMID: 33467425Free PMC Article
Horton TM, Whitlock JA, Lu X, O'Brien MM, Borowitz MJ, Devidas M, Raetz EA, Brown PA, Carroll WL, Hunger SP
Br J Haematol 2019 Jul;186(2):274-285. Epub 2019 Apr 7 doi: 10.1111/bjh.15919. PMID: 30957229Free PMC Article
Gardner RA, Finney O, Annesley C, Brakke H, Summers C, Leger K, Bleakley M, Brown C, Mgebroff S, Kelly-Spratt KS, Hoglund V, Lindgren C, Oron AP, Li D, Riddell SR, Park JR, Jensen MC
Blood 2017 Jun 22;129(25):3322-3331. Epub 2017 Apr 13 doi: 10.1182/blood-2017-02-769208. PMID: 28408462Free PMC Article

Recent systematic reviews

Aamir S, Anwar MY, Khalid F, Khan SI, Ali MA, Khattak ZE
Clin Lymphoma Myeloma Leuk 2021 Apr;21(4):e334-e347. Epub 2020 Dec 17 doi: 10.1016/j.clml.2020.12.010. PMID: 33573914

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...