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Acquired factor VII deficiency

MedGen UID:
1388639
•Concept ID:
C4331989
•
Disease or Syndrome
Synonyms: Acquired Factor VII Deficiency; acquired factor VII deficiency
 
Monarch Initiative: MONDO:0035738
Orphanet: ORPHA599495

Definition

An acquired coagulation disorder characterized by the partial or complete absence of factor VII activity in the blood. [from NCI]

Professional guidelines

PubMed

International recommendations on the diagnosis and treatment of acquired hemophilia A.
Tiede A, Collins P, Knoebl P, Teitel J, Kessler C, Shima M, Di Minno G, d'Oiron R, Salaj P, Jiménez-Yuste V, Huth-Kühne A, Giangrande P
Haematologica 2020 Jul;105(7):1791-1801. Epub 2020 May 7 doi: 10.3324/haematol.2019.230771. PMID: 32381574Free PMC Article
Factor VII Deficiency: From Basics to Clinical Laboratory Diagnosis and Patient Management.
Sevenet PO, Kaczor DA, Depasse F
Clin Appl Thromb Hemost 2017 Oct;23(7):703-710. Epub 2016 Oct 3 doi: 10.1177/1076029616670257. PMID: 27701084
Hereditary and acquired C1-inhibitor-dependent angioedema: from pathophysiology to treatment.
Zeerleder S, Levi M
Ann Med 2016;48(4):256-67. Epub 2016 Mar 26 doi: 10.3109/07853890.2016.1162909. PMID: 27018196

Recent clinical studies

Etiology

Factor VII Deficiency in Patients Receiving Chronic Packed Cell Transfusions.
Abu-Quider A, Asleh M, Fruchtman Y, Ben-Harosh M, Beck G, Abuhasira R, Kapelushnik J
J Pediatr Hematol Oncol 2021 Mar 1;43(2):e268-e271. doi: 10.1097/MPH.0000000000001854. PMID: 32520845
Management of Labour and Delivery in a Patient With Acquired Factor VII Deficiency With Inhibitor: A Case Report.
Matei A, Dolan S, Andrews J, Rivard GÉ
J Obstet Gynaecol Can 2016 Feb;38(2):160-3. Epub 2016 Mar 2 doi: 10.1016/j.jogc.2015.11.002. PMID: 27032741
Acquired factor VII deficiency in hematopoietic stem cell transplant recipients.
Toor AA, Slungaard A, Hedner U, Weisdorf DJ, Key NS
Bone Marrow Transplant 2002 Mar;29(5):403-8. doi: 10.1038/sj.bmt.1703381. PMID: 11919730

Diagnosis

Acquired factor VII deficiency in pediatric inflammatory bowel disease: Report of three cases.
Çakar S, Eren G, Karapınar TH, Ecevıt ÇÖ, Bekem Ö
Arab J Gastroenterol 2023 Nov;24(4):256-258. Epub 2023 Nov 22 doi: 10.1016/j.ajg.2023.10.002. PMID: 37993374
Acquired Factor VII Deficiency Presenting with Bleeding Diathesis in a 52-Year-Old Black Man in Botswana.
Ncube M, Majaha K, Nkhori OF, Charumbira T, Mosenye SM, Shailemo D, Rwegerera GM
Clin Lab 2022 Mar 1;68(3) doi: 10.7754/Clin.Lab.2021.210702. PMID: 35254019
Acquired Factor VII deficiency - a rare but important consideration.
Zaidi MH, Stanley A, Khan M
Scott Med J 2019 Aug;64(3):119-122. Epub 2019 May 29 doi: 10.1177/0036933019853167. PMID: 31142211
Isolated acquired factor VII deficiency: review of the literature.
Mulliez SM, Devreese KM
Acta Clin Belg 2016 Apr;71(2):63-70. Epub 2016 Mar 3 doi: 10.1179/2295333715Y.0000000073. PMID: 26400474
Acquired factor VII deficiency in hematopoietic stem cell transplant recipients.
Toor AA, Slungaard A, Hedner U, Weisdorf DJ, Key NS
Bone Marrow Transplant 2002 Mar;29(5):403-8. doi: 10.1038/sj.bmt.1703381. PMID: 11919730

Therapy

Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis.
Wolf EB, Li D, Fernandez AJ, Gardner LB, Rivera CE, Wysokinska EM, Shaikh ME, Tun HW, Roy V, Alhaj Moustafa M
J Investig Med High Impact Case Rep 2023 Jan-Dec;11:23247096231209543. doi: 10.1177/23247096231209543. PMID: 37919949Free PMC Article
Subdural Hematoma From an Acquired Factor VII Deficiency: Is It the Lupus or the Anticoagulant?
Abdulsalam MA, Abdulsalam AJ, Özçakar L
J Clin Rheumatol 2021 Dec 1;27(8S):S553-S554. doi: 10.1097/RHU.0000000000001016. PMID: 30896459
Acute Myelogenous Leukemia With Trisomy 8 and Concomitant Acquired Factor VII Deficiency.
Moosavi L, Bowen J, Coleman J, Heidari A, Cobos E
J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619872657. doi: 10.1177/2324709619872657. PMID: 31496295Free PMC Article
Isolated acquired factor VII deficiency: review of the literature.
Mulliez SM, Devreese KM
Acta Clin Belg 2016 Apr;71(2):63-70. Epub 2016 Mar 3 doi: 10.1179/2295333715Y.0000000073. PMID: 26400474
Acquired factor VII deficiency in hematopoietic stem cell transplant recipients.
Toor AA, Slungaard A, Hedner U, Weisdorf DJ, Key NS
Bone Marrow Transplant 2002 Mar;29(5):403-8. doi: 10.1038/sj.bmt.1703381. PMID: 11919730

Prognosis

Acquired Factor VII Deficiency Presenting with Bleeding Diathesis in a 52-Year-Old Black Man in Botswana.
Ncube M, Majaha K, Nkhori OF, Charumbira T, Mosenye SM, Shailemo D, Rwegerera GM
Clin Lab 2022 Mar 1;68(3) doi: 10.7754/Clin.Lab.2021.210702. PMID: 35254019
Factor VII Deficiency in Patients Receiving Chronic Packed Cell Transfusions.
Abu-Quider A, Asleh M, Fruchtman Y, Ben-Harosh M, Beck G, Abuhasira R, Kapelushnik J
J Pediatr Hematol Oncol 2021 Mar 1;43(2):e268-e271. doi: 10.1097/MPH.0000000000001854. PMID: 32520845
Isolated acquired factor VII deficiency: review of the literature.
Mulliez SM, Devreese KM
Acta Clin Belg 2016 Apr;71(2):63-70. Epub 2016 Mar 3 doi: 10.1179/2295333715Y.0000000073. PMID: 26400474
Acquired factor VII deficiency associated with acute myeloid leukemia.
Anoun S, Lamchahab M, Oukkache B, Qachouh M, Benchekroun S, Quessar A
Blood Coagul Fibrinolysis 2015 Apr;26(3):331-3. doi: 10.1097/MBC.0000000000000024. PMID: 24991944
Acquired factor VII deficiency associated with aplastic anaemia: correction with bone marrow transplantation.
Weisdorf D, Hasegawa D, Fair DS
Br J Haematol 1989 Mar;71(3):409-13. doi: 10.1111/j.1365-2141.1989.tb04299.x. PMID: 2649142

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