U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ventricular and Brain Stem Ependymal Tumor

MedGen UID:
1388921
•Concept ID:
C4331499
•
Neoplastic Process

Definition

A finding indicating the presence of an ependymal tumor in a brain ventricle and the brain stem. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVentricular and Brain Stem Ependymal Tumor

Recent clinical studies

Etiology

Bi-allelic variations in CRB2, encoding the crumbs cell polarity complex component 2, lead to non-communicating hydrocephalus due to atresia of the aqueduct of sylvius and central canal of the medulla.
Tessier A, Roux N, Boutaud L, Lunel E, Hakkakian L, Parisot M, Garfa-Traoré M, Ichkou A, Elkhartoufi N, Bole C, Nitschke P, Amiel J, Martinovic J, Encha-Razavi F, Attié-Bitach T, Thomas S
Acta Neuropathol Commun 2023 Feb 20;11(1):29. doi: 10.1186/s40478-023-01519-8. PMID: 36803301Free PMC Article
Use of preoperative FLAIR MRI and ependymal proximity of tumor enhancement as surrogate markers of brain tumor origin.
Smith TR, Hulou MM, Abecassis J, Das S, Chandler JP
J Clin Neurosci 2015 Sep;22(9):1397-402. Epub 2015 Jun 6 doi: 10.1016/j.jocn.2015.02.029. PMID: 26055954
Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells.
Quiñones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A
J Comp Neurol 2006 Jan 20;494(3):415-34. doi: 10.1002/cne.20798. PMID: 16320258

Diagnosis

Symptomatic infratentorial ependymal cyst arising from the medulla: a case report with review of literature.
Cavallaro J, Singha S, Chakrabarti B, Gopalakrishnan E, Harshan M, Pramanik BK, McKeown A, Boockvar JA
Neurochirurgie 2024 Jul;70(4):101553. Epub 2024 Mar 27 doi: 10.1016/j.neuchi.2024.101553. PMID: 38547561
Well-developed Cerebellum in an Ovarian Mature Teratoma From a Pregnant Female.
Sauer MA, Coy S, Quade BJ, Nucci MR
Int J Gynecol Pathol 2022 Nov 1;41(6):615-621. Epub 2021 Dec 27 doi: 10.1097/PGP.0000000000000848. PMID: 34954707
Ependymoma Presenting as a -Rim-Enhancing Lesion in the Brainstem.
Malbari F, Aldave G, Birchansky SB, Paulino AC, Lopez-Terrada DH, Mohila CA, Zhao S, Chintagumpala M
Pediatr Neurosurg 2021;56(5):455-459. Epub 2021 Jun 18 doi: 10.1159/000516001. PMID: 34148044
Use of preoperative FLAIR MRI and ependymal proximity of tumor enhancement as surrogate markers of brain tumor origin.
Smith TR, Hulou MM, Abecassis J, Das S, Chandler JP
J Clin Neurosci 2015 Sep;22(9):1397-402. Epub 2015 Jun 6 doi: 10.1016/j.jocn.2015.02.029. PMID: 26055954
The trapped temporal horn: a trap in neuroradiological diagnosis.
Smith H, Moody D, Ball M, Laster W, Kelly DL Jr, Alexander E Jr
Neurosurgery 1979 Aug;5(2):245-9. doi: 10.1227/00006123-197908000-00008. PMID: 481728

Therapy

EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation.
Abdi K, Neves G, Pyun J, Kiziltug E, Ahrens A, Kuo CT
Cell Rep 2019 Aug 20;28(8):2012-2022.e4. doi: 10.1016/j.celrep.2019.07.056. PMID: 31433979Free PMC Article

Prognosis

Organotypic distribution of stem cell markers in formalin-fixed brain harboring glioblastoma multiforme.
Schrot RJ, Ma JH, Greco CM, Arias AD, Angelastro JM
J Neurooncol 2007 Nov;85(2):149-57. Epub 2007 May 22 doi: 10.1007/s11060-007-9401-8. PMID: 17516028

Clinical prediction guides

Comparative characterization of the human and mouse third ventricle germinal zones.
Dahiya S, Lee DY, Gutmann DH
J Neuropathol Exp Neurol 2011 Jul;70(7):622-33. doi: 10.1097/NEN.0b013e31822200aa. PMID: 21666496Free PMC Article
Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells.
Quiñones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A
J Comp Neurol 2006 Jan 20;494(3):415-34. doi: 10.1002/cne.20798. PMID: 16320258

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...