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Ejection Systolic Heart Murmur

MedGen UID:
1389228
•Concept ID:
C0694547
•
Finding
Synonym: Systolic ejection murmur

Definition

A heart murmur that occurs predominantly in midsystole, when ejection volume and velocity of blood flow are at their maximum; it is produced by ejection of blood into the pulmonary artery and aorta. It is typically crescendo-decrescendo. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEjection Systolic Heart Murmur

Professional guidelines

PubMed

A review of the pathophysiology, diagnosis, and treatment of aortic valve stenosis in elderly patients.
Aronow WS
Hosp Pract (1995) 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. PMID: 24145591
Diagnosis and management of acyanotic heart disease: part II -- left-to-right shunt lesions.
Syamasundar Rao P
Indian J Pediatr 2005 Jun;72(6):503-12. doi: 10.1007/BF02724429. PMID: 15985740
Diagnosis and management of acyanotic heart disease: part I -- obstructive lesions.
Syamasundar Rao P
Indian J Pediatr 2005 Jun;72(6):496-502. PMID: 15985739

Recent clinical studies

Etiology

Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Accidental Heart Murmurs.
Begic E, Begic Z
Med Arch 2017 Aug;71(4):284-287. doi: 10.5455/medarh.2017.71.284-287. PMID: 28974851Free PMC Article
Systolic ejection click versus split first heart sound: Are our ears deceiving us?
Hoeting NM, McCracken CE, McConnell M, Sallee D, Iannucci GJ, Oster ME
Congenit Heart Dis 2017 Jul;12(4):417-420. Epub 2017 Mar 16 doi: 10.1111/chd.12460. PMID: 28299882
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Valvular aortic stenosis in the elderly.
Aronow WS
Cardiol Rev 2007 Sep-Oct;15(5):217-25. doi: 10.1097/CRD.0b013e31805f6796. PMID: 17700380

Diagnosis

Murmurs other than the early diastolic murmur in aortic dissection.
Jolobe OMP
Am J Emerg Med 2021 Nov;49:133-136. Epub 2021 May 21 doi: 10.1016/j.ajem.2021.05.041. PMID: 34102459
Accidental Heart Murmurs.
Begic E, Begic Z
Med Arch 2017 Aug;71(4):284-287. doi: 10.5455/medarh.2017.71.284-287. PMID: 28974851Free PMC Article
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Therapy

A review of the pathophysiology, diagnosis, and treatment of aortic valve stenosis in elderly patients.
Aronow WS
Hosp Pract (1995) 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. PMID: 24145591
Aortic stenosis.
Aronow WS
Compr Ther 2007 Winter;33(4):174-83. doi: 10.1007/s12019-007-8021-8. PMID: 18025609
Valvular aortic stenosis in the elderly.
Aronow WS
Cardiol Rev 2007 Sep-Oct;15(5):217-25. doi: 10.1097/CRD.0b013e31805f6796. PMID: 17700380
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Prognosis

Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Acute Tachycardia-Induced Cardiomyopathy: A Case Report.
Amr M
Am J Case Rep 2021 May 10;22:e930732. doi: 10.12659/AJCR.930732. PMID: 33970894Free PMC Article
A review of the pathophysiology, diagnosis, and treatment of aortic valve stenosis in elderly patients.
Aronow WS
Hosp Pract (1995) 2013 Oct-Nov;41(4):66-77. doi: 10.3810/hp.2013.10.1082. PMID: 24145591
Cardiac abnormalities in birth asphyxia.
Ranjit MS
Indian J Pediatr 2000 Mar;67(3 Suppl):S26-9. PMID: 11129917
Mitral valve regurgitation.
O'Rourke RA, Crawford MH
Curr Probl Cardiol 1984 May;9(2):1-52. doi: 10.1016/0146-2806(84)90021-5. PMID: 6375982

Clinical prediction guides

Does Iron Deficiency Affect the Heart in Children?
Demir F, Kayali S, Gokcebay DG
J Pediatr Hematol Oncol 2022 Apr 1;44(3):84-88. doi: 10.1097/MPH.0000000000002170. PMID: 33843814
Screening for aortic stenosis using physical examination and echocardiography.
Abe Y
J Echocardiogr 2021 Jun;19(2):80-85. Epub 2021 Jan 7 doi: 10.1007/s12574-020-00511-8. PMID: 33415574
Systolic ejection click versus split first heart sound: Are our ears deceiving us?
Hoeting NM, McCracken CE, McConnell M, Sallee D, Iannucci GJ, Oster ME
Congenit Heart Dis 2017 Jul;12(4):417-420. Epub 2017 Mar 16 doi: 10.1111/chd.12460. PMID: 28299882
Prediction of aortic stenosis-related events in patients with systolic ejection murmur using pocket-sized echocardiography.
Furukawa A, Abe Y, Ito M, Tanaka C, Ito K, Komatsu R, Haze K, Naruko T, Yoshiyama M, Yoshikawa J
J Cardiol 2017 Jan;69(1):189-194. Epub 2016 Mar 21 doi: 10.1016/j.jjcc.2016.02.021. PMID: 27012751
Cardiac pearls.
Harvey WP
Dis Mon 1994 Feb;40(2):41-113. doi: 10.1016/0011-5029(94)90002-7. PMID: 8306847

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