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Nutritional Vitamin D Deficiency Rickets

MedGen UID:
1389570
•Concept ID:
C4331919
•
Disease or Syndrome

Definition

Nutritional rickets due to dietary deficiency of vitamin D. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNutritional Vitamin D Deficiency Rickets

Professional guidelines

PubMed

Nutritional rickets & osteomalacia: A practical approach to management.
Uday S, Högler W
Indian J Med Res 2020 Oct;152(4):356-367. doi: 10.4103/ijmr.IJMR_1961_19. PMID: 33380700Free PMC Article
Comparison of oral versus injectable vitamin-D for the treatment of nutritional vitamin-D deficiency rickets.
Billoo AG, Murtaza G, Memon MA, Khaskheli SA, Iqbal K, Rao MH
J Coll Physicians Surg Pak 2009 Jul;19(7):428-31. PMID: 19576150
Comparison of low and high dose of vitamin D treatment in nutritional vitamin D deficiency rickets.
Cesur Y, Caksen H, Gündem A, Kirimi E, Odabaş D
J Pediatr Endocrinol Metab 2003 Oct-Nov;16(8):1105-9. doi: 10.1515/jpem.2003.16.8.1105. PMID: 14594170

Recent clinical studies

Etiology

Comparison of oral versus injectable vitamin-D for the treatment of nutritional vitamin-D deficiency rickets.
Billoo AG, Murtaza G, Memon MA, Khaskheli SA, Iqbal K, Rao MH
J Coll Physicians Surg Pak 2009 Jul;19(7):428-31. PMID: 19576150
Rickets in the Dairy State.
Mylott BM, Kump T, Bolton ML, Greenbaum LA
WMJ 2004;103(5):84-7. PMID: 15553572
Comparison of low and high dose of vitamin D treatment in nutritional vitamin D deficiency rickets.
Cesur Y, Caksen H, Gündem A, Kirimi E, Odabaş D
J Pediatr Endocrinol Metab 2003 Oct-Nov;16(8):1105-9. doi: 10.1515/jpem.2003.16.8.1105. PMID: 14594170
Nutritional vitamin D deficiency rickets in Sudanese children.
el Hag AI, Karrar ZA
Ann Trop Paediatr 1995;15(1):69-76. doi: 10.1080/02724936.1995.11747751. PMID: 7598440
Rickets then and now.
Harrrison HE, Harrison HC
J Pediatr 1975 Dec;87(6 Pt 2):1144-51. doi: 10.1016/s0022-3476(75)80129-6. PMID: 1102648

Diagnosis

Difficulty Achieving Vitamin D Sufficiency With High-Dose Oral Repletion Therapy in Infants With Cholestasis.
Jensen M, Abu-El-Haija M, Bishop W, Rahhal RM
J Pediatr Gastroenterol Nutr 2015 Aug;61(2):187-9. doi: 10.1097/MPG.0000000000000751. PMID: 25651487
Dilated cardiomyopathy due to nutritional vitamin D deficiency rickets.
Kosecik M, Ertas T
Pediatr Int 2007 Jun;49(3):397-9. doi: 10.1111/j.1442-200X.2007.02367.x. PMID: 17532844
Dilated cardiomyopathy as a first sign of nutritional vitamin D deficiency rickets in infancy.
Abdullah M, Bigras JL, McCrindle BW
Can J Cardiol 1999 Jun;15(6):699-701. PMID: 10375722
Nutritional vitamin D deficiency rickets in Sudanese children.
el Hag AI, Karrar ZA
Ann Trop Paediatr 1995;15(1):69-76. doi: 10.1080/02724936.1995.11747751. PMID: 7598440
Single-day therapy for nutritional vitamin D-deficiency rickets: a preferred method.
Shah BR, Finberg L
J Pediatr 1994 Sep;125(3):487-90. doi: 10.1016/s0022-3476(05)83303-7. PMID: 8071764

Therapy

Difficulty Achieving Vitamin D Sufficiency With High-Dose Oral Repletion Therapy in Infants With Cholestasis.
Jensen M, Abu-El-Haija M, Bishop W, Rahhal RM
J Pediatr Gastroenterol Nutr 2015 Aug;61(2):187-9. doi: 10.1097/MPG.0000000000000751. PMID: 25651487
Comparison of oral versus injectable vitamin-D for the treatment of nutritional vitamin-D deficiency rickets.
Billoo AG, Murtaza G, Memon MA, Khaskheli SA, Iqbal K, Rao MH
J Coll Physicians Surg Pak 2009 Jul;19(7):428-31. PMID: 19576150
Comparison of low and high dose of vitamin D treatment in nutritional vitamin D deficiency rickets.
Cesur Y, Caksen H, Gündem A, Kirimi E, Odabaş D
J Pediatr Endocrinol Metab 2003 Oct-Nov;16(8):1105-9. doi: 10.1515/jpem.2003.16.8.1105. PMID: 14594170
Single-day therapy for nutritional vitamin D-deficiency rickets: a preferred method.
Shah BR, Finberg L
J Pediatr 1994 Sep;125(3):487-90. doi: 10.1016/s0022-3476(05)83303-7. PMID: 8071764
Rickets then and now.
Harrrison HE, Harrison HC
J Pediatr 1975 Dec;87(6 Pt 2):1144-51. doi: 10.1016/s0022-3476(75)80129-6. PMID: 1102648

Prognosis

Dilated cardiomyopathy due to nutritional vitamin D deficiency rickets.
Kosecik M, Ertas T
Pediatr Int 2007 Jun;49(3):397-9. doi: 10.1111/j.1442-200X.2007.02367.x. PMID: 17532844
Comparison of low and high dose of vitamin D treatment in nutritional vitamin D deficiency rickets.
Cesur Y, Caksen H, Gündem A, Kirimi E, Odabaş D
J Pediatr Endocrinol Metab 2003 Oct-Nov;16(8):1105-9. doi: 10.1515/jpem.2003.16.8.1105. PMID: 14594170

Clinical prediction guides

Linear growth in relation to the circulating concentrations of insulin-like growth factor I, parathyroid hormone, and 25-hydroxy vitamin D in children with nutritional rickets before and after treatment: endocrine adaptation to vitamin D deficiency.
Soliman AT, Al Khalaf F, Alhemaidi N, Al Ali M, Al Zyoud M, Yakoot K
Metabolism 2008 Jan;57(1):95-102. doi: 10.1016/j.metabol.2007.08.011. PMID: 18078865

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