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Loss of eyelashes

MedGen UID:
1390509
Concept ID:
C4316878
Finding
Synonyms: Ciliary Madarosis; Eyelashes fell out; Milphosis; Missing eyelashes
 
HPO: HP:0011457

Definition

This term refers to the loss of eyelashes that were previously present. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLoss of eyelashes

Conditions with this feature

Cutaneous porphyria
MedGen UID:
102408
Concept ID:
C0162530
Disease or Syndrome
Congenital erythropoietic porphyria (CEP) is characterized in most individuals by severe cutaneous photosensitivity with blistering and increased friability of the skin over light-exposed areas. Onset in most affected individuals occurs at birth or early infancy. The first manifestation is often pink-to-dark red discoloration of the urine. Hemolytic anemia is common and can range from mild to severe, with some affected individuals requiring chronic blood transfusions. Porphyrin deposition may lead to corneal ulcers and scarring, reddish-brown discoloration of the teeth (erythrodontia), and bone loss and/or expansion of the bone marrow. The phenotypic spectrum, however, is broad and ranges from nonimmune hydrops fetalis in utero to late-onset disease with only mild cutaneous manifestations in adulthood.

Professional guidelines

PubMed

Krema H, Herrmann E, Albert-Green A, Payne D, Laperriere N, Chung C
Br J Ophthalmol 2013 Jun;97(6):730-4. Epub 2013 Mar 26 doi: 10.1136/bjophthalmol-2012-302991. PMID: 23532618

Recent clinical studies

Etiology

Li J, Wang Y, Li D, Zhou N, Du A, Qin X, Hu J
J Plast Reconstr Aesthet Surg 2022 Oct;75(10):3789-3794. Epub 2022 Jun 18 doi: 10.1016/j.bjps.2022.06.028. PMID: 36045014
Bitton E, Courey C, Giancola P, Diaconu V, Wise J, Wittich W
Clin Exp Optom 2017 Nov;100(6):583-589. Epub 2017 Jan 25 doi: 10.1111/cxo.12507. PMID: 28122407
Leung C, Johnson D, Pang R, Kratky V
Can Fam Physician 2015 Jan;61(1):e43-9. PMID: 25756148Free PMC Article
Kosik-Bogacka DI, Łanocha N, Łanocha A, Czepita D, Grobelny A, Zdziarska B, Kalisińska E
Ophthalmic Epidemiol 2013 Jun;20(3):159-63. doi: 10.3109/09286586.2013.789532. PMID: 23713917
Garcia-Martin E, Gil-Arribas LM, Idoipe M, Alfaro J, Pueyo V, Pablo LE, Fernandez FJ
Br J Ophthalmol 2011 Oct;95(10):1393-6. Epub 2011 Jan 17 doi: 10.1136/bjo.2010.193078. PMID: 21242584

Diagnosis

Casale JJ, Uddin SB, Proia AD
Ophthalmic Plast Reconstr Surg 2023 Nov-Dec 01;39(6):e199-e202. Epub 2023 Jul 21 doi: 10.1097/IOP.0000000000002465. PMID: 37486338
Suwal R, Dhakal P, Joshi P
Nepal J Ophthalmol 2020 Jan;12(23):113-138. doi: 10.3126/nepjoph.v12i1.25454. PMID: 32799251
Nguyen HV, Jakobiec FA, Zakka FR, Yoon MK
Surv Ophthalmol 2018 Jul-Aug;63(4):589-594. Epub 2017 Oct 3 doi: 10.1016/j.survophthal.2017.09.007. PMID: 28986312
Leung C, Johnson D, Pang R, Kratky V
Can Fam Physician 2015 Jan;61(1):e43-9. PMID: 25756148Free PMC Article
Garcia-Martin E, Gil-Arribas LM, Idoipe M, Alfaro J, Pueyo V, Pablo LE, Fernandez FJ
Br J Ophthalmol 2011 Oct;95(10):1393-6. Epub 2011 Jan 17 doi: 10.1136/bjo.2010.193078. PMID: 21242584

Therapy

Runnels J, Acosta G, Rose A, Haynes M, Nikolaidis D, Wong A, Fiani B
Clin Transl Oncol 2021 Oct;23(10):2066-2077. Epub 2021 Apr 7 doi: 10.1007/s12094-021-02610-z. PMID: 33826082
Bitton E, Courey C, Giancola P, Diaconu V, Wise J, Wittich W
Clin Exp Optom 2017 Nov;100(6):583-589. Epub 2017 Jan 25 doi: 10.1111/cxo.12507. PMID: 28122407
Garcia-Martin E, Gil-Arribas LM, Idoipe M, Alfaro J, Pueyo V, Pablo LE, Fernandez FJ
Br J Ophthalmol 2011 Oct;95(10):1393-6. Epub 2011 Jan 17 doi: 10.1136/bjo.2010.193078. PMID: 21242584
Mohammadpour M, Javadi MA
Cornea 2006 Jan;25(1):112-4. doi: 10.1097/01.ico.0000179928.20522.3a. PMID: 16331052
Stannard CE, Sealy GR, Hering ER, Pereira SB, Knowles R, Hill JC
Ophthalmology 2000 May;107(5):951-8. doi: 10.1016/s0161-6420(00)00061-0. PMID: 10811089

Prognosis

Leung C, Johnson D, Pang R, Kratky V
Can Fam Physician 2015 Jan;61(1):e43-9. PMID: 25756148Free PMC Article
Krema H, Herrmann E, Albert-Green A, Payne D, Laperriere N, Chung C
Br J Ophthalmol 2013 Jun;97(6):730-4. Epub 2013 Mar 26 doi: 10.1136/bjophthalmol-2012-302991. PMID: 23532618
Garcia-Martin E, Gil-Arribas LM, Idoipe M, Alfaro J, Pueyo V, Pablo LE, Fernandez FJ
Br J Ophthalmol 2011 Oct;95(10):1393-6. Epub 2011 Jan 17 doi: 10.1136/bjo.2010.193078. PMID: 21242584
Stannard CE, Sealy GR, Hering ER, Pereira SB, Knowles R, Hill JC
Ophthalmology 2000 May;107(5):951-8. doi: 10.1016/s0161-6420(00)00061-0. PMID: 10811089
Fraunfelder FT, Zacarian SA, Limmer BL, Wingfield D
Ophthalmology 1980 Jun;87(6):461-5. doi: 10.1016/s0161-6420(80)35207-x. PMID: 7413134

Clinical prediction guides

Li J, Wang Y, Li D, Zhou N, Du A, Qin X, Hu J
J Plast Reconstr Aesthet Surg 2022 Oct;75(10):3789-3794. Epub 2022 Jun 18 doi: 10.1016/j.bjps.2022.06.028. PMID: 36045014
Leung C, Johnson D, Pang R, Kratky V
Can Fam Physician 2015 Jan;61(1):e43-9. PMID: 25756148Free PMC Article
Kosik-Bogacka DI, Łanocha N, Łanocha A, Czepita D, Grobelny A, Zdziarska B, Kalisińska E
Ophthalmic Epidemiol 2013 Jun;20(3):159-63. doi: 10.3109/09286586.2013.789532. PMID: 23713917
Pujol RM, Nadal C, Matias-Guiu X, Peyrí J, Ferrándiz C, Palou J, de Moragas JM
J Am Acad Dermatol 1998 Nov;39(5 Pt 2):853-7. doi: 10.1016/s0190-9622(98)70365-2. PMID: 9810915

Recent systematic reviews

Runnels J, Acosta G, Rose A, Haynes M, Nikolaidis D, Wong A, Fiani B
Clin Transl Oncol 2021 Oct;23(10):2066-2077. Epub 2021 Apr 7 doi: 10.1007/s12094-021-02610-z. PMID: 33826082

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