U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Arteriosclerosis obliterans

MedGen UID:
13915
•Concept ID:
C0003851
•
Disease or Syndrome
Synonyms: Arteriosclerosis Obliterans; Obliterans, Arteriosclerosis
SNOMED CT: Arteriosclerosis obliterans (361133006)
 
Monarch Initiative: MONDO:0006659

Definition

Common occlusive arterial disease which is caused by atherosclerosis. It is characterized by lesions in the innermost layer (arterial intima) of arteries including the aorta and its branches to the extremities. Risk factors include smoking, hyperlipidemia, and hypertension. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVArteriosclerosis obliterans

Professional guidelines

PubMed

Excimer laser atherectomy combined with drug-coated balloon angioplasty for the treatment of femoropopliteal arteriosclerosis obliterans.
Su Z, Li Y, Yang S, Guo J, Guo L, Gu Y
Ann R Coll Surg Engl 2022 Nov;104(9):667-672. Epub 2022 Apr 21 doi: 10.1308/rcsann.2021.0335. PMID: 35446161Free PMC Article
Characteristics of revascularization treatment for arteriosclerosis obliterans in patients with and without hemodialysis.
Hoshino J, Fujimoto Y, Naruse Y, Hasegawa E, Suwabe T, Sawa N, Takemoto F, Ishiwata S, Ohno M, Ubara Y, Yamagata K, Takaichi K
Circ J 2010 Nov;74(11):2426-33. Epub 2010 Oct 2 doi: 10.1253/circj.cj-09-0910. PMID: 20938099
The clinical features and treatment of arteriosclerosis obliterans with diabetes.
Tsushima N, Matsuo H, Hayashi T, Homma S
Diabetes 1996 Jul;45 Suppl 3:S101-4. doi: 10.2337/diab.45.3.s101. PMID: 8674871

Recent clinical studies

Etiology

Relationship between Angiotensin II, Vascular Endothelial Growth Factor, and Arteriosclerosis Obliterans.
Liu Y, Cui Y, Zhou Z, Liu B, Liu Z, Li G
Dis Markers 2023;2023:1316821. Epub 2023 Feb 21 doi: 10.1155/2023/1316821. PMID: 36865500Free PMC Article
EFFECTIVENESS OF LISINOPRIL AND AMLODIPINE COMBINATION AT HYPERTENSION WITH COMORBIDITY OF ARTERIOSCLEROSIS OBLITERANS IN GENERAL PRACTICE.
Babinets LS, Levchuk RD, Halabitska IM, Kryskiv OI
Wiad Lek 2022;75(10):2407-2411. doi: 10.36740/WLek202210116. PMID: 36472269
Clinical Efficacy of Interventional Therapy on Lower Extremity Arteriosclerosis Obliterans and Prognostic Factors.
Xiao D, Song J
Comput Math Methods Med 2022;2022:9190292. Epub 2022 Aug 4 doi: 10.1155/2022/9190292. PMID: 35966252Free PMC Article
Hospital Discharge Teaching for Patients with Peripheral Vascular Disease.
Wiltz-James LM, Foley J
Crit Care Nurs Clin North Am 2019 Mar;31(1):91-95. Epub 2018 Dec 22 doi: 10.1016/j.cnc.2018.11.003. PMID: 30736938
Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells.
Sun XL, Law BY, de Seabra Rodrigues Dias IR, Mok SWF, He YZ, Wong VK
Atherosclerosis 2017 Oct;265:258-265. Epub 2017 Aug 18 doi: 10.1016/j.atherosclerosis.2017.08.009. PMID: 28864202

Diagnosis

Relationship between Angiotensin II, Vascular Endothelial Growth Factor, and Arteriosclerosis Obliterans.
Liu Y, Cui Y, Zhou Z, Liu B, Liu Z, Li G
Dis Markers 2023;2023:1316821. Epub 2023 Feb 21 doi: 10.1155/2023/1316821. PMID: 36865500Free PMC Article
Clinical Efficacy of Interventional Therapy on Lower Extremity Arteriosclerosis Obliterans and Prognostic Factors.
Xiao D, Song J
Comput Math Methods Med 2022;2022:9190292. Epub 2022 Aug 4 doi: 10.1155/2022/9190292. PMID: 35966252Free PMC Article
The clinical features and treatment of arteriosclerosis obliterans with diabetes.
Tsushima N, Matsuo H, Hayashi T, Homma S
Diabetes 1996 Jul;45 Suppl 3:S101-4. doi: 10.2337/diab.45.3.s101. PMID: 8674871
Arteriosclerosis obliterans. Diagnostic and nonoperative treatment options.
Ku A, Nagler W
Postgrad Med 1995 Nov;98(5):203-4, 207-10, 212. PMID: 7479455
Dextran anaphylaxis.
Maddi VI, Wyso EM, Zinner EN
Angiology 1969 May;20(5):243-8. doi: 10.1177/000331976902000502. PMID: 5768784

Therapy

EFFECTIVENESS OF LISINOPRIL AND AMLODIPINE COMBINATION AT HYPERTENSION WITH COMORBIDITY OF ARTERIOSCLEROSIS OBLITERANS IN GENERAL PRACTICE.
Babinets LS, Levchuk RD, Halabitska IM, Kryskiv OI
Wiad Lek 2022;75(10):2407-2411. doi: 10.36740/WLek202210116. PMID: 36472269
Factors Affecting Intermittent Infusion Hemodiafiltration.
Eiki K, Otake T
Blood Purif 2019;48 Suppl 1:17-21. Epub 2019 Nov 21 doi: 10.1159/000503876. PMID: 31752001
Endarteritis obliterans in the pathogenesis of Buerger's disease from the pathological and immunohistochemical points of view.
Kobayashi M, Sugimoto M, Komori K
Circ J 2014;78(12):2819-26. Epub 2014 Oct 8 doi: 10.1253/circj.cj-14-0656. PMID: 25298073
Dextran anaphylaxis.
Maddi VI, Wyso EM, Zinner EN
Angiology 1969 May;20(5):243-8. doi: 10.1177/000331976902000502. PMID: 5768784
Arteriosclerosis obliterans.
DEDICHEN J
Bibl Cardiol 1958;8:55-8. PMID: 13596335

Prognosis

Effect of diabetes on the prognosis, serum inflammatory factors, and quality of life of patients with lower extremity arteriosclerosis obliterans after vascular intervention: a retrospective comparative cohort study.
Zhao H, Zhuo T, Hao X, Fan X, Zhao P
Ann Palliat Med 2022 Aug;11(8):2720-2729. doi: 10.21037/apm-22-827. PMID: 36064362
Clinical Efficacy of Interventional Therapy on Lower Extremity Arteriosclerosis Obliterans and Prognostic Factors.
Xiao D, Song J
Comput Math Methods Med 2022;2022:9190292. Epub 2022 Aug 4 doi: 10.1155/2022/9190292. PMID: 35966252Free PMC Article
Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Predict Severity and Prognosis of Lower Limb Arteriosclerosis Obliterans.
Ye M, Qian X, Guo X, Wang H, Ni Q, Zhao Y, Xue G, Deng H, Zhang L
Ann Vasc Surg 2020 Apr;64:221-227. Epub 2019 Oct 23 doi: 10.1016/j.avsg.2019.09.005. PMID: 31655109
Brachial-ankle pulse wave velocity, cardio-ankle vascular index, and prognosis.
Ato D
Vasc Health Risk Manag 2018;14:321-348. Epub 2018 Oct 24 doi: 10.2147/VHRM.S179366. PMID: 30498357Free PMC Article
Outcomes in Patients with Critical Limb Ischemia due to Arteriosclerosis Obliterans Who Did Not Undergo Arterial Reconstruction.
Akagi D, Hoshina K, Akai A, Yamamoto K
Int Heart J 2018 Sep 26;59(5):1041-1046. Epub 2018 Aug 11 doi: 10.1536/ihj.17-592. PMID: 30101855

Clinical prediction guides

Relationship between Angiotensin II, Vascular Endothelial Growth Factor, and Arteriosclerosis Obliterans.
Liu Y, Cui Y, Zhou Z, Liu B, Liu Z, Li G
Dis Markers 2023;2023:1316821. Epub 2023 Feb 21 doi: 10.1155/2023/1316821. PMID: 36865500Free PMC Article
Effect of diabetes on the prognosis, serum inflammatory factors, and quality of life of patients with lower extremity arteriosclerosis obliterans after vascular intervention: a retrospective comparative cohort study.
Zhao H, Zhuo T, Hao X, Fan X, Zhao P
Ann Palliat Med 2022 Aug;11(8):2720-2729. doi: 10.21037/apm-22-827. PMID: 36064362
Clinical Significance of Endothelin-1 And C Reaction Protein in Restenosis After the Intervention of Lower Extremity Arteriosclerosis Obliterans.
Lian W, Nie H, Yuan Y, Wang K, Chen W, Ding L
J Invest Surg 2021 Jul;34(7):765-770. Epub 2020 Jan 29 doi: 10.1080/08941939.2019.1690600. PMID: 31996054
Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Predict Severity and Prognosis of Lower Limb Arteriosclerosis Obliterans.
Ye M, Qian X, Guo X, Wang H, Ni Q, Zhao Y, Xue G, Deng H, Zhang L
Ann Vasc Surg 2020 Apr;64:221-227. Epub 2019 Oct 23 doi: 10.1016/j.avsg.2019.09.005. PMID: 31655109
Brachial-ankle pulse wave velocity, cardio-ankle vascular index, and prognosis.
Ato D
Vasc Health Risk Manag 2018;14:321-348. Epub 2018 Oct 24 doi: 10.2147/VHRM.S179366. PMID: 30498357Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...