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Harlequin phenomenon

MedGen UID:
1393866
•Concept ID:
C4476835
•
Disease or Syndrome
HPO: HP:0025531

Definition

The Harlequin phenomenon consists of a sudden change in skin color, resulting in two different body colors, one on each half of the body. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHarlequin phenomenon

Recent clinical studies

Etiology

Differential hypoxemia and the clinical significance of venous drainage position during extracorporeal membrane oxygenation.
Falk L, Hultman J, Broman LM
Perfusion 2023 May;38(4):818-825. Epub 2022 May 11 doi: 10.1177/02676591221090667. PMID: 35543368
Impact of the inspiratory oxygen fraction on the cardiac output during jugulo-femoral venoarterial extracorporeal membrane oxygenation in the rat.
Edinger F, Schneck E, Schulte C, Schmidt G, Gehron J, Sander M, Koch C
BMC Cardiovasc Disord 2022 Apr 15;22(1):174. doi: 10.1186/s12872-022-02613-w. PMID: 35428203Free PMC Article
Pitfalls of cannulation for extracorporeal life support: review of the literature and illustrative case presentation.
Geyer M, Gohrbandt B, Sagoschen I, Hartmann T, Post F, Vahl CF, Münzel T
J Artif Organs 2018 Mar;21(1):8-16. Epub 2017 Nov 9 doi: 10.1007/s10047-017-1004-3. PMID: 29124458
The Harlequin phenomenon.
Januário G, Salgado M
J Eur Acad Dermatol Venereol 2011 Dec;25(12):1381-4. Epub 2011 May 17 doi: 10.1111/j.1468-3083.2011.04124.x. PMID: 21575077

Diagnosis

Harlequin syndrome in a young girl: An opportunity to rethink the terminology.
Douvali T, Papageorgiou V, Gerochristou M, Gerodimou M, Tampouratzi E, Chasapi V
Pediatr Dermatol 2021 Jul;38(4):984-985. Epub 2021 Jul 5 doi: 10.1111/pde.14681. PMID: 34227168

Therapy

Impact of the inspiratory oxygen fraction on the cardiac output during jugulo-femoral venoarterial extracorporeal membrane oxygenation in the rat.
Edinger F, Schneck E, Schulte C, Schmidt G, Gehron J, Sander M, Koch C
BMC Cardiovasc Disord 2022 Apr 15;22(1):174. doi: 10.1186/s12872-022-02613-w. PMID: 35428203Free PMC Article
Images in Anesthesiology: Harlequin Phenomenon in a Newborn after Induction of General Anesthesia.
Pekurovsky A, Monteleone MP
Anesthesiology 2016 May;124(5):1166. doi: 10.1097/ALN.0000000000000911. PMID: 26528778
Intractable vascular autonomic dysregulation (Harlequin phenomenon) in two brothers: another indication for propranolol?
Janmohamed SR, Madern GC, de Laat PC, Oranje AP; Workgroup on Vascular Abnormalities Rotterdam
Dermatol Ther 2014 Jul-Aug;27(4):230-2. Epub 2014 Apr 17 doi: 10.1111/dth.12124. PMID: 24750208

Prognosis

Impact of the inspiratory oxygen fraction on the cardiac output during jugulo-femoral venoarterial extracorporeal membrane oxygenation in the rat.
Edinger F, Schneck E, Schulte C, Schmidt G, Gehron J, Sander M, Koch C
BMC Cardiovasc Disord 2022 Apr 15;22(1):174. doi: 10.1186/s12872-022-02613-w. PMID: 35428203Free PMC Article
Pitfalls of cannulation for extracorporeal life support: review of the literature and illustrative case presentation.
Geyer M, Gohrbandt B, Sagoschen I, Hartmann T, Post F, Vahl CF, Münzel T
J Artif Organs 2018 Mar;21(1):8-16. Epub 2017 Nov 9 doi: 10.1007/s10047-017-1004-3. PMID: 29124458
The Harlequin phenomenon.
Januário G, Salgado M
J Eur Acad Dermatol Venereol 2011 Dec;25(12):1381-4. Epub 2011 May 17 doi: 10.1111/j.1468-3083.2011.04124.x. PMID: 21575077

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