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Cardiac sarcoidosis

MedGen UID:
140260
•Concept ID:
C0392077
•
Disease or Syndrome
Synonyms: Cardiac Sarcoidosis; cardiac sarcoidosis; heart sarcoidosis; sarcoidosis of heart
SNOMED CT: Cardiac sarcoidosis (75403004)
 
Monarch Initiative: MONDO:0001707

Definition

Sarcoidosis affecting the tissues of the heart. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac sarcoidosis

Professional guidelines

PubMed

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.
Crouser ED, Maier LA, Wilson KC, Bonham CA, Morgenthau AS, Patterson KC, Abston E, Bernstein RC, Blankstein R, Chen ES, Culver DA, Drake W, Drent M, Gerke AK, Ghobrial M, Govender P, Hamzeh N, James WE, Judson MA, Kellermeyer L, Knight S, Koth LL, Poletti V, Raman SV, Tukey MH, Westney GE, Baughman RP
Am J Respir Crit Care Med 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST. PMID: 32293205Free PMC Article

Recent clinical studies

Etiology

Risk stratification of patients with cardiac sarcoidosis: the ILLUMINATE-CS registry.
Nabeta T, Kitai T, Naruse Y, Taniguchi T, Yoshioka K, Tanaka H, Okumura T, Sato S, Baba Y, Kida K, Tamaki Y, Matsumoto S, Matsue Y
Eur Heart J 2022 Sep 21;43(36):3450-3459. doi: 10.1093/eurheartj/ehac323. PMID: 35781334
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Restrictive Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.
Muchtar E, Blauwet LA, Gertz MA
Circ Res 2017 Sep 15;121(7):819-837. doi: 10.1161/CIRCRESAHA.117.310982. PMID: 28912185
HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis.
Birnie DH, Sauer WH, Bogun F, Cooper JM, Culver DA, Duvernoy CS, Judson MA, Kron J, Mehta D, Cosedis Nielsen J, Patel AR, Ohe T, Raatikainen P, Soejima K
Heart Rhythm 2014 Jul;11(7):1305-23. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.03.043. PMID: 24819193

Diagnosis

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac sarcoidosis.
Sohn DW, Park JB
Heart 2023 Jul 12;109(15):1132-1138. doi: 10.1136/heartjnl-2022-321379. PMID: 36631144
Transcriptional and Immune Landscape of Cardiac Sarcoidosis.
Liu J, Ma P, Lai L, Villanueva A, Koenig A, Bean GR, Bowles DE, Glass C, Watson M, Lavine KJ, Lin CY
Circ Res 2022 Sep 30;131(8):654-669. Epub 2022 Sep 16 doi: 10.1161/CIRCRESAHA.121.320449. PMID: 36111531Free PMC Article
Sarcoidosis-Related Cardiomyopathy: Current Knowledge, Challenges, and Future Perspectives State-of-the-Art Review.
Gilotra NA, Griffin JM, Pavlovic N, Houston BA, Chasler J, Goetz C, Chrispin J, Sharp M, Kasper EK, Chen ES, Blankstein R, Cooper LT, Joyce E, Sheikh FH
J Card Fail 2022 Jan;28(1):113-132. Epub 2021 Jul 11 doi: 10.1016/j.cardfail.2021.06.016. PMID: 34260889Free PMC Article
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538

Therapy

Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Challenges in Cardiac and Pulmonary Sarcoidosis: JACC State-of-the-Art Review.
Trivieri MG, Spagnolo P, Birnie D, Liu P, Drake W, Kovacic JC, Baughman R, Fayad ZA, Judson MA
J Am Coll Cardiol 2020 Oct 20;76(16):1878-1901. doi: 10.1016/j.jacc.2020.08.042. PMID: 33059834Free PMC Article
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Advanced sarcoidosis.
Baughman RP, Wells A
Curr Opin Pulm Med 2019 Sep;25(5):497-504. doi: 10.1097/MCP.0000000000000612. PMID: 31365384
Cardiac Sarcoidosis.
Tan JL, Fong HK, Birati EY, Han Y
Am J Cardiol 2019 Feb 1;123(3):513-522. Epub 2018 Nov 6 doi: 10.1016/j.amjcard.2018.10.021. PMID: 30503798

Prognosis

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Transcriptional and Immune Landscape of Cardiac Sarcoidosis.
Liu J, Ma P, Lai L, Villanueva A, Koenig A, Bean GR, Bowles DE, Glass C, Watson M, Lavine KJ, Lin CY
Circ Res 2022 Sep 30;131(8):654-669. Epub 2022 Sep 16 doi: 10.1161/CIRCRESAHA.121.320449. PMID: 36111531Free PMC Article
Biomarkers in the Diagnosis and Prognosis of Sarcoidosis: Current Use and Future Prospects.
Kraaijvanger R, Janssen Bonás M, Vorselaars ADM, Veltkamp M
Front Immunol 2020;11:1443. Epub 2020 Jul 14 doi: 10.3389/fimmu.2020.01443. PMID: 32760396Free PMC Article
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Restrictive Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.
Muchtar E, Blauwet LA, Gertz MA
Circ Res 2017 Sep 15;121(7):819-837. doi: 10.1161/CIRCRESAHA.117.310982. PMID: 28912185

Clinical prediction guides

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Transcriptional and Immune Landscape of Cardiac Sarcoidosis.
Liu J, Ma P, Lai L, Villanueva A, Koenig A, Bean GR, Bowles DE, Glass C, Watson M, Lavine KJ, Lin CY
Circ Res 2022 Sep 30;131(8):654-669. Epub 2022 Sep 16 doi: 10.1161/CIRCRESAHA.121.320449. PMID: 36111531Free PMC Article
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Cardiac Sarcoidosis.
Tan JL, Fong HK, Birati EY, Han Y
Am J Cardiol 2019 Feb 1;123(3):513-522. Epub 2018 Nov 6 doi: 10.1016/j.amjcard.2018.10.021. PMID: 30503798
Restrictive Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.
Muchtar E, Blauwet LA, Gertz MA
Circ Res 2017 Sep 15;121(7):819-837. doi: 10.1161/CIRCRESAHA.117.310982. PMID: 28912185

Recent systematic reviews

Diagnostic Accuracy of Cardiac MRI versus FDG PET for Cardiac Sarcoidosis: A Systematic Review and Meta-Analysis.
Aitken M, Chan MV, Urzua Fresno C, Farrell A, Islam N, McInnes MDF, Iwanochko M, Balter M, Moayedi Y, Thavendiranathan P, Metser U, Veit-Haibach P, Hanneman K
Radiology 2022 Sep;304(3):566-579. Epub 2022 May 17 doi: 10.1148/radiol.213170. PMID: 35579526
Cardiac sarcoidosis: systematic review of the literature on corticosteroid and immunosuppressive therapies.
Stievenart J, Le Guenno G, Ruivard M, Rieu V, André M, Grobost V
Eur Respir J 2022 May;59(5) Epub 2022 May 5 doi: 10.1183/13993003.00449-2021. PMID: 34531273Free PMC Article
Corticosteroid and Immunosuppressant Therapy for Cardiac Sarcoidosis: A Systematic Review.
Fazelpour S, Sadek MM, Nery PB, Beanlands RS, Tzemos N, Toma M, Birnie DH
J Am Heart Assoc 2021 Sep 7;10(17):e021183. Epub 2021 Sep 2 doi: 10.1161/JAHA.121.021183. PMID: 34472360Free PMC Article
Outcome of implantable cardioverter defibrillator in cardiac sarcoidosis: a systematic review and meta-analysis.
Halawa A, Jain R, Turagam MK, Kusumoto FM, Woldu HG, Gautam S
J Interv Card Electrophysiol 2020 Aug;58(2):233-242. Epub 2020 Feb 15 doi: 10.1007/s10840-020-00705-1. PMID: 32062788
Corticosteroid therapy for cardiac sarcoidosis: a systematic review.
Sadek MM, Yung D, Birnie DH, Beanlands RS, Nery PB
Can J Cardiol 2013 Sep;29(9):1034-41. Epub 2013 Apr 24 doi: 10.1016/j.cjca.2013.02.004. PMID: 23623644

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