U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cardiac sarcoidosis

MedGen UID:
140260
•Concept ID:
C0392077
•
Disease or Syndrome
Synonyms: Cardiac Sarcoidosis; cardiac sarcoidosis; heart sarcoidosis; sarcoidosis of heart
SNOMED CT: Cardiac sarcoidosis (75403004)
 
Monarch Initiative: MONDO:0001707

Definition

Sarcoidosis affecting the tissues of the heart. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac sarcoidosis

Professional guidelines

PubMed

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.
Crouser ED, Maier LA, Wilson KC, Bonham CA, Morgenthau AS, Patterson KC, Abston E, Bernstein RC, Blankstein R, Chen ES, Culver DA, Drake W, Drent M, Gerke AK, Ghobrial M, Govender P, Hamzeh N, James WE, Judson MA, Kellermeyer L, Knight S, Koth LL, Poletti V, Raman SV, Tukey MH, Westney GE, Baughman RP
Am J Respir Crit Care Med 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST. PMID: 32293205Free PMC Article

Recent clinical studies

Etiology

Management of cardiac sarcoidosis.
Sharma R, Kouranos V, Cooper LT, Metra M, Ristic A, Heidecker B, Baksi J, Wicks E, Merino JL, Klingel K, Imazio M, de Chillou C, Tschöpe C, Kuchynka P, Petersen SE, McDonagh T, Lüscher T, Filippatos G
Eur Heart J 2024 Aug 9;45(30):2697-2726. doi: 10.1093/eurheartj/ehae356. PMID: 38923509
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Restrictive Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.
Muchtar E, Blauwet LA, Gertz MA
Circ Res 2017 Sep 15;121(7):819-837. doi: 10.1161/CIRCRESAHA.117.310982. PMID: 28912185
Severe Sarcoidosis.
Kouranos V, Jacob J, Wells AU
Clin Chest Med 2015 Dec;36(4):715-26. Epub 2015 Oct 1 doi: 10.1016/j.ccm.2015.08.012. PMID: 26593144

Diagnosis

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac sarcoidosis.
Sohn DW, Park JB
Heart 2023 Jul 12;109(15):1132-1138. doi: 10.1136/heartjnl-2022-321379. PMID: 36631144
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Cardiac Sarcoidosis.
Tan JL, Fong HK, Birati EY, Han Y
Am J Cardiol 2019 Feb 1;123(3):513-522. Epub 2018 Nov 6 doi: 10.1016/j.amjcard.2018.10.021. PMID: 30503798
Cardiac Sarcoidosis.
Birnie DH, Nery PB, Ha AC, Beanlands RS
J Am Coll Cardiol 2016 Jul 26;68(4):411-21. doi: 10.1016/j.jacc.2016.03.605. PMID: 27443438

Therapy

Management of cardiac sarcoidosis.
Sharma R, Kouranos V, Cooper LT, Metra M, Ristic A, Heidecker B, Baksi J, Wicks E, Merino JL, Klingel K, Imazio M, de Chillou C, Tschöpe C, Kuchynka P, Petersen SE, McDonagh T, Lüscher T, Filippatos G
Eur Heart J 2024 Aug 9;45(30):2697-2726. doi: 10.1093/eurheartj/ehae356. PMID: 38923509
Cardiac sarcoidosis: diagnosis and management.
Markatis E, Afthinos A, Antonakis E, Papanikolaou IC
Rev Cardiovasc Med 2020 Sep 30;21(3):321-338. doi: 10.31083/j.rcm.2020.03.102. PMID: 33070538
Challenges in Cardiac and Pulmonary Sarcoidosis: JACC State-of-the-Art Review.
Trivieri MG, Spagnolo P, Birnie D, Liu P, Drake W, Kovacic JC, Baughman R, Fayad ZA, Judson MA
J Am Coll Cardiol 2020 Oct 20;76(16):1878-1901. doi: 10.1016/j.jacc.2020.08.042. PMID: 33059834Free PMC Article
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Cardiac Sarcoidosis.
Tan JL, Fong HK, Birati EY, Han Y
Am J Cardiol 2019 Feb 1;123(3):513-522. Epub 2018 Nov 6 doi: 10.1016/j.amjcard.2018.10.021. PMID: 30503798

Prognosis

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac Sarcoidosis.
Birnie DH
Semin Respir Crit Care Med 2020 Oct;41(5):626-640. Epub 2020 Jun 27 doi: 10.1055/s-0040-1712535. PMID: 32593175
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Cardiac Sarcoidosis.
Birnie DH, Nery PB, Ha AC, Beanlands RS
J Am Coll Cardiol 2016 Jul 26;68(4):411-21. doi: 10.1016/j.jacc.2016.03.605. PMID: 27443438
Cardiac Sarcoidosis.
Birnie D, Ha AC, Gula LJ, Chakrabarti S, Beanlands RS, Nery P
Clin Chest Med 2015 Dec;36(4):657-68. Epub 2015 Sep 11 doi: 10.1016/j.ccm.2015.08.008. PMID: 26593140

Clinical prediction guides

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis.
Lehtonen J, Uusitalo V, Pöyhönen P, Mäyränpää MI, Kupari M
Eur Heart J 2023 May 1;44(17):1495-1510. doi: 10.1093/eurheartj/ehad067. PMID: 36924191Free PMC Article
Cardiac Sarcoidosis.
Birnie DH
Semin Respir Crit Care Med 2020 Oct;41(5):626-640. Epub 2020 Jun 27 doi: 10.1055/s-0040-1712535. PMID: 32593175
Cardiac Sarcoidosis.
Mankad P, Mitchell B, Birnie D, Kron J
Curr Cardiol Rep 2019 Nov 25;21(12):152. doi: 10.1007/s11886-019-1238-1. PMID: 31768666Free PMC Article
Cardiac Sarcoidosis.
Tan JL, Fong HK, Birati EY, Han Y
Am J Cardiol 2019 Feb 1;123(3):513-522. Epub 2018 Nov 6 doi: 10.1016/j.amjcard.2018.10.021. PMID: 30503798
Cardiac Sarcoidosis.
Birnie DH, Nery PB, Ha AC, Beanlands RS
J Am Coll Cardiol 2016 Jul 26;68(4):411-21. doi: 10.1016/j.jacc.2016.03.605. PMID: 27443438

Recent systematic reviews

Risk Stratification in Cardiac Sarcoidosis With Cardiac Positron Emission Tomography: A Systematic Review and Meta-Analysis.
Kafil TS, Shaikh OM, Fanous Y, Benjamen J, Hashmi MM, Jawad A, Dahrouj T, Abazid RM, Swiha M, Romsa J, Beanlands RSB, Ruddy TD, Mielniczuk L, Birnie DH, Tzemos N
JACC Cardiovasc Imaging 2024 Sep;17(9):1079-1097. Epub 2024 Aug 7 doi: 10.1016/j.jcmg.2024.05.013. PMID: 39115497
Cardiac sarcoidosis: systematic review of the literature on corticosteroid and immunosuppressive therapies.
Stievenart J, Le Guenno G, Ruivard M, Rieu V, André M, Grobost V
Eur Respir J 2022 May;59(5) Epub 2022 May 5 doi: 10.1183/13993003.00449-2021. PMID: 34531273Free PMC Article
Corticosteroid and Immunosuppressant Therapy for Cardiac Sarcoidosis: A Systematic Review.
Fazelpour S, Sadek MM, Nery PB, Beanlands RS, Tzemos N, Toma M, Birnie DH
J Am Heart Assoc 2021 Sep 7;10(17):e021183. Epub 2021 Sep 2 doi: 10.1161/JAHA.121.021183. PMID: 34472360Free PMC Article
Outcome of implantable cardioverter defibrillator in cardiac sarcoidosis: a systematic review and meta-analysis.
Halawa A, Jain R, Turagam MK, Kusumoto FM, Woldu HG, Gautam S
J Interv Card Electrophysiol 2020 Aug;58(2):233-242. Epub 2020 Feb 15 doi: 10.1007/s10840-020-00705-1. PMID: 32062788
Corticosteroid therapy for cardiac sarcoidosis: a systematic review.
Sadek MM, Yung D, Birnie DH, Beanlands RS, Nery PB
Can J Cardiol 2013 Sep;29(9):1034-41. Epub 2013 Apr 24 doi: 10.1016/j.cjca.2013.02.004. PMID: 23623644

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...