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Trisomy 9

MedGen UID:
140938
Concept ID:
C0432411
Disease or Syndrome
Synonyms: Chromosome 9, trisomy; Duplication 9
SNOMED CT: Trisomy 9 (205650008)

Definition

A chromosomal abnormality consisting of the presence of a third copy of chromosome 9 in somatic cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrisomy 9

Professional guidelines

PubMed

Topbas Selcuki NF, Senol G, Esin D, Ozkose ZG, Caypinar SS, Bornaun H, Cetin BA, Yuksel MA
Arch Gynecol Obstet 2022 Sep;306(3):745-752. Epub 2022 Jan 4 doi: 10.1007/s00404-021-06346-7. PMID: 34981204
Baer RJ, Flessel MC, Jelliffe-Pawlowski LL, Goldman S, Hudgins L, Hull AD, Norton ME, Currier RJ
Obstet Gynecol 2015 Oct;126(4):753-759. doi: 10.1097/AOG.0000000000001040. PMID: 26348180
Francke U, Benirschke K, Jones OW
Humangenetik 1975 Sep 23;29(3):243-50. doi: 10.1007/BF00297630. PMID: 1165103

Recent clinical studies

Etiology

Li H, Lu L, Yao Y, Gao T, Jiang Y, Zhang C, Liu N, Song J, Wang W, Liu L
Taiwan J Obstet Gynecol 2022 Nov;61(6):965-970. doi: 10.1016/j.tjog.2022.07.006. PMID: 36427999
Kosyk MS, Carlson AR, Zapatero ZD, Kalmar CL, Cielo CM, Lioy J, Bartlett SP, Taylor JA, Swanson JW
Ann Plast Surg 2022 Jan 1;88(1):54-58. doi: 10.1097/SAP.0000000000002891. PMID: 34176894
Chen CP, Lin HM, Su YN, Chern SR, Tsai FJ, Wu PC, Lee CC, Chen YT, Lee MS, Pan CW, Wang W
Taiwan J Obstet Gynecol 2010 Sep;49(3):341-50. doi: 10.1016/S1028-4559(10)60071-X. PMID: 21056321
Chen CP
Taiwan J Obstet Gynecol 2007 Dec;46(4):325-35. doi: 10.1016/S1028-4559(08)60002-9. PMID: 18182338
Stipoljev F, Kos M, Kos M, Miskovi B, Matijevic R, Hafner T, Kurjak A
J Matern Fetal Neonatal Med 2003 Jul;14(1):65-9. doi: 10.1080/jmf.14.1.65.69. PMID: 14563095

Diagnosis

Li M, Glass J, Du X, Dubbs H, Harr MH, Falk M, Smolarek T, Hopkin RJ, Zackai E, Sheppard SE
Am J Med Genet A 2021 Aug;185(8):2374-2383. Epub 2021 May 10 doi: 10.1002/ajmg.a.62251. PMID: 33969943Free PMC Article
DeLoache KB, Bradshaw WT
Adv Neonatal Care 2014 Jun;14(3):165-71. doi: 10.1097/ANC.0000000000000082. PMID: 24858667
Chen CP, Lin HM, Su YN, Chern SR, Tsai FJ, Wu PC, Lee CC, Chen YT, Lee MS, Pan CW, Wang W
Taiwan J Obstet Gynecol 2010 Sep;49(3):341-50. doi: 10.1016/S1028-4559(10)60071-X. PMID: 21056321
Chen CP
Taiwan J Obstet Gynecol 2007 Dec;46(4):325-35. doi: 10.1016/S1028-4559(08)60002-9. PMID: 18182338
Van den Berg C, Ramlakhan SK, Van Opstal D, Brandenburg H, Halley DJ, Los FJ
Prenat Diagn 1997 Oct;17(10):933-40. doi: 10.1002/(sici)1097-0223(199710)17:10<933::aid-pd179>3.3.co;2-s. PMID: 9358573

Therapy

Legister CS, Harding DC, Morgan SJ, Guillaume TJ
Spine Deform 2023 May;11(3):759-764. Epub 2022 Dec 22 doi: 10.1007/s43390-022-00624-3. PMID: 36547810
Henningsen MB, Gulisano HA, Bjarkam CR
J Med Case Rep 2022 May 27;16(1):206. doi: 10.1186/s13256-022-03424-5. PMID: 35619116Free PMC Article
Riley CJ, Moore T, Eagelston L, Burkett D, Auerbach S, Ing RJ
Anesth Prog 2017 Spring;64(1):29-32. doi: 10.2344/anpr-63-04-01. PMID: 28128660Free PMC Article
Tiong K, Cotterill A, Falhammar H
BMC Med Genet 2010 Feb 16;11:26. doi: 10.1186/1471-2350-11-26. PMID: 20158889Free PMC Article
Wilson GN, Raj A, Baker D
Am J Med Genet 1985 Feb;20(2):277-82. doi: 10.1002/ajmg.1320200211. PMID: 3976721

Prognosis

Ferreres JC, Planas S, Martínez-Sáez EA, Vendrell T, Peg V, Salcedo MT, Ramón Y Cajal S, Torán N
Pediatr Dev Pathol 2008 Jan-Feb;11(1):23-9. doi: 10.2350/06-08-0143.1. PMID: 18237231
Kor-Anantakul O, Suwanrath C, Kanngurn S, Rujirabanjerd S, Suntharasaj T, Pinjaroen S
Am J Perinatol 2006 Feb;23(2):131-5. doi: 10.1055/s-2006-931804. PMID: 16506121
Van den Berg C, Ramlakhan SK, Van Opstal D, Brandenburg H, Halley DJ, Los FJ
Prenat Diagn 1997 Oct;17(10):933-40. doi: 10.1002/(sici)1097-0223(199710)17:10<933::aid-pd179>3.3.co;2-s. PMID: 9358573
Cantú ES, Eicher DJ, Pai GS, Donahue CJ, Harley RA
Am J Med Genet 1996 Apr 24;62(4):330-5. doi: 10.1002/(SICI)1096-8628(19960424)62:4<330::AID-AJMG1>3.0.CO;2-V. PMID: 8723059
Arnold GL, Kirby RS, Stern TP, Sawyer JR
Am J Med Genet 1995 Apr 10;56(3):252-7. doi: 10.1002/ajmg.1320560303. PMID: 7778584

Clinical prediction guides

Kannan TP, Hemlatha S, Ankathil R, Zilfalil BA
Indian J Pediatr 2009 Jul;76(7):745-6. Epub 2009 May 27 doi: 10.1007/s12098-009-0158-2. PMID: 19475342
Cantú ES, Eicher DJ, Pai GS, Donahue CJ, Harley RA
Am J Med Genet 1996 Apr 24;62(4):330-5. doi: 10.1002/(SICI)1096-8628(19960424)62:4<330::AID-AJMG1>3.0.CO;2-V. PMID: 8723059
Wooldridge J, Zunich J
Am J Med Genet 1995 Apr 10;56(3):258-64. doi: 10.1002/ajmg.1320560304. PMID: 7778585
Arnold GL, Kirby RS, Stern TP, Sawyer JR
Am J Med Genet 1995 Apr 10;56(3):252-7. doi: 10.1002/ajmg.1320560303. PMID: 7778584
Maximilian C, Duca D, Pop T, Toncescu N, Ioan D
Endocrinologie 1980 Oct-Dec;18(4):273-5. PMID: 6451918

Recent systematic reviews

Dirvanskyte P, Gurram B, Bolton C, Warner N, Jones KDJ, Griffin HR; Genomics England Research Consortium, Park JY, Keller KM, Gilmour KC, Hambleton S, Muise AM, Wysocki C, Uhlig HH
J Crohns Colitis 2023 Jan 27;17(1):49-60. doi: 10.1093/ecco-jcc/jjac103. PMID: 35907265Free PMC Article

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