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Decreased peak expiratory flow rate

MedGen UID:
141710
Concept ID:
C0520843
Finding
Synonym: Decreased Peak Expiratory Flowrate
SNOMED CT: Decreased peak expiratory flow rate (7206008)

Definition

Decreased expiratory peak flow measurement achieved during forced expiration that primarily reflects changes in upper airway conductance and may be of limited use in evaluation of changes in peripheral airway conductance. Evaluation of peak flow performance is subjective, and, therefore, acceptability criteria are lacking. Because the maneuver is effort and volume dependent, the patient must be encouraged to perform as vigorously as clinically feasible. The results of subjective evaluation may be difficult to interpret consistently. A validated dyspnea rating scale may be useful. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased peak expiratory flow rate

Professional guidelines

PubMed

Pollart SM, Compton RM, Elward KS
Am Fam Physician 2011 Jul 1;84(1):40-7. PMID: 21766754
Kemp JP
Am J Respir Med 2003;2(2):139-56. doi: 10.1007/BF03256645. PMID: 14720013
Weiler JM
Allergy Asthma Proc 1996 Nov-Dec;17(6):315-25. doi: 10.2500/108854196778606437. PMID: 8993724

Recent clinical studies

Etiology

Fujita K, Ohkubo H, Nakano A, Takeda N, Fukumitsu K, Fukuda S, Kanemitsu Y, Uemura T, Tajiri T, Maeno K, Ito Y, Oguri T, Ozawa Y, Murase T, Niimi A
Chron Respir Dis 2022 Jan-Dec;19:14799731221114153. doi: 10.1177/14799731221114153. PMID: 35792724Free PMC Article
Murphy KR, Chipps BE
Ann Allergy Asthma Immunol 2020 Mar;124(3):267-276.e3. Epub 2019 Dec 2 doi: 10.1016/j.anai.2019.11.030. PMID: 31805357
Saxena Y, Purwar B, Upmanyu R
Indian J Chest Dis Allied Sci 2011 Jan-Mar;53(1):29-33. PMID: 21446222
Kneyber MC, van Heerde M, Twisk JW, Plötz FB, Markhors DG
Crit Care 2009;13(3):R71. Epub 2009 May 15 doi: 10.1186/cc7880. PMID: 19450268Free PMC Article
Feldman J, Traver GA, Taussig LM
Am Rev Respir Dis 1979 Feb;119(2):239-45. doi: 10.1164/arrd.1979.119.2.239. PMID: 434596

Diagnosis

Kadota N, Shinohara T, Machida H, Nakanishi H, Suehiro F, Toda H, Yoshino T, Ogushi F
BMC Res Notes 2015 Jun 6;8:223. doi: 10.1186/s13104-015-1218-5. PMID: 26048050Free PMC Article
Daman HR
J Asthma 1984;21(5):331-7. doi: 10.3109/02770908409077444. PMID: 6501170

Therapy

Murphy KR, Chipps BE
Ann Allergy Asthma Immunol 2020 Mar;124(3):267-276.e3. Epub 2019 Dec 2 doi: 10.1016/j.anai.2019.11.030. PMID: 31805357
Dahl R, Engel M, Dusser D, Halpin D, Kerstjens HAM, Zaremba-Pechmann L, Moroni-Zentgraf P, Busse WW, Bateman ED
Respir Med 2016 Sep;118:102-111. Epub 2016 Jul 2 doi: 10.1016/j.rmed.2016.07.001. PMID: 27578478
Kneyber MC, van Heerde M, Twisk JW, Plötz FB, Markhors DG
Crit Care 2009;13(3):R71. Epub 2009 May 15 doi: 10.1186/cc7880. PMID: 19450268Free PMC Article
Kesavachandran C, Singh VK, Mathur N, Rastogi SK, Siddiqui MK, Reddy MM, Bharti RS, Khan AM
Redox Rep 2006;11(4):159-62. doi: 10.1179/135100006X116673. PMID: 16984738
Thuillez C, Richer C, Duhazé P, Bergougnan L, Giudicelli JF
Eur J Clin Pharmacol 1985;29(4):405-11. doi: 10.1007/BF00613453. PMID: 3912184

Prognosis

Fujita K, Ohkubo H, Nakano A, Takeda N, Fukumitsu K, Fukuda S, Kanemitsu Y, Uemura T, Tajiri T, Maeno K, Ito Y, Oguri T, Ozawa Y, Murase T, Niimi A
Chron Respir Dis 2022 Jan-Dec;19:14799731221114153. doi: 10.1177/14799731221114153. PMID: 35792724Free PMC Article
Kadota N, Shinohara T, Machida H, Nakanishi H, Suehiro F, Toda H, Yoshino T, Ogushi F
BMC Res Notes 2015 Jun 6;8:223. doi: 10.1186/s13104-015-1218-5. PMID: 26048050Free PMC Article
Saxena Y, Purwar B, Upmanyu R
Indian J Chest Dis Allied Sci 2011 Jan-Mar;53(1):29-33. PMID: 21446222

Clinical prediction guides

Fujita K, Ohkubo H, Nakano A, Takeda N, Fukumitsu K, Fukuda S, Kanemitsu Y, Uemura T, Tajiri T, Maeno K, Ito Y, Oguri T, Ozawa Y, Murase T, Niimi A
Chron Respir Dis 2022 Jan-Dec;19:14799731221114153. doi: 10.1177/14799731221114153. PMID: 35792724Free PMC Article
Kadota N, Shinohara T, Machida H, Nakanishi H, Suehiro F, Toda H, Yoshino T, Ogushi F
BMC Res Notes 2015 Jun 6;8:223. doi: 10.1186/s13104-015-1218-5. PMID: 26048050Free PMC Article
Saxena Y, Purwar B, Upmanyu R
Indian J Chest Dis Allied Sci 2011 Jan-Mar;53(1):29-33. PMID: 21446222

Recent systematic reviews

Murphy KR, Chipps BE
Ann Allergy Asthma Immunol 2020 Mar;124(3):267-276.e3. Epub 2019 Dec 2 doi: 10.1016/j.anai.2019.11.030. PMID: 31805357

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