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Ectopic calcitonin production

MedGen UID:
141747
•Concept ID:
C0521799
•
Disease or Syndrome
Synonyms: Ectopic Calcitonin Production; Ectopic Calcitonin Secretion; Ectopic Calcitonin Secretion Syndrome
SNOMED CT: Ectopic calcitonin production (95836003)

Definition

A syndrome characterized by abnormal secretion of calcitonin in conjunction with neoplastic growth occurring anywhere in the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEctopic calcitonin production

Professional guidelines

PubMed

A Review of Current Clinical Concepts in the Pathophysiology, Etiology, Diagnosis, and Management of Hypercalcemia.
Tonon CR, Silva TAAL, Pereira FWL, Queiroz DAR, Junior ELF, Martins D, Azevedo PS, Okoshi MP, Zornoff LAM, de Paiva SAR, Minicucci MF, Polegato BF
Med Sci Monit 2022 Feb 26;28:e935821. doi: 10.12659/MSM.935821. PMID: 35217631Free PMC Article

Recent clinical studies

Diagnosis

Differentiation between thyroidal and ectopic calcitonin secretion in patients with coincidental thyroid nodules and pancreatic tumors - a report of two cases.
Schneider R, Heverhagen AE, Moll R, Bartsch DK, Schlosser K
Exp Clin Endocrinol Diabetes 2010 Aug;118(8):520-3. Epub 2009 Aug 18 doi: 10.1055/s-0029-1231083. PMID: 19691012
Metastatic cervical carcinoma with ectopic calcitonin production presenting as a thyroid mass.
Singh R, Bibbo M, Cunnane MF, Carlson JA, de Papp AE
Endocr Pract 2002 Jan-Feb;8(1):50-3. doi: 10.4158/EP.8.1.50. PMID: 11939761

Therapy

Differentiation between thyroidal and ectopic calcitonin secretion in patients with coincidental thyroid nodules and pancreatic tumors - a report of two cases.
Schneider R, Heverhagen AE, Moll R, Bartsch DK, Schlosser K
Exp Clin Endocrinol Diabetes 2010 Aug;118(8):520-3. Epub 2009 Aug 18 doi: 10.1055/s-0029-1231083. PMID: 19691012

Prognosis

Differentiation between thyroidal and ectopic calcitonin secretion in patients with coincidental thyroid nodules and pancreatic tumors - a report of two cases.
Schneider R, Heverhagen AE, Moll R, Bartsch DK, Schlosser K
Exp Clin Endocrinol Diabetes 2010 Aug;118(8):520-3. Epub 2009 Aug 18 doi: 10.1055/s-0029-1231083. PMID: 19691012
Metastatic cervical carcinoma with ectopic calcitonin production presenting as a thyroid mass.
Singh R, Bibbo M, Cunnane MF, Carlson JA, de Papp AE
Endocr Pract 2002 Jan-Feb;8(1):50-3. doi: 10.4158/EP.8.1.50. PMID: 11939761

Clinical prediction guides

Differentiation between thyroidal and ectopic calcitonin secretion in patients with coincidental thyroid nodules and pancreatic tumors - a report of two cases.
Schneider R, Heverhagen AE, Moll R, Bartsch DK, Schlosser K
Exp Clin Endocrinol Diabetes 2010 Aug;118(8):520-3. Epub 2009 Aug 18 doi: 10.1055/s-0029-1231083. PMID: 19691012

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