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Breast cyst

MedGen UID:
14220
•Concept ID:
C0006144
•
Anatomical Abnormality
Synonyms: Breast Cyst; Breast Cysts; Cyst, Breast; Cysts, Breast
SNOMED CT: Cyst of breast (399294002)
 
Monarch Initiative: MONDO:0001011

Definition

A cystic lesion located in breast tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast cyst

Professional guidelines

PubMed

Diffusion-weighted MR imaging: role in the differential diagnosis of breast lesions.
Altay C, Balci P, Altay S, Karasu S, Saydam S, Canda T, Dicle O
JBR-BTR 2014 Jul-Aug;97(4):211-6. doi: 10.5334/jbr-btr.80. PMID: 25603628
Lack of utility in clinical practice of cytologic examination of nonbloody cyst fluid from palpable breast cysts.
Hindle WH, Arias RD, Florentine B, Whang J
Am J Obstet Gynecol 2000 Jun;182(6):1300-5. doi: 10.1067/mob.2000.106184. PMID: 10871442
Management of palpable breast lumps. Consensus guideline for family physicians.
Heisey R, Mahoney L, Watson B
Can Fam Physician 1999 Aug;45:1926-32. PMID: 10463093Free PMC Article

Recent clinical studies

Etiology

Benign Disorders of the Breast in Pregnancy and Lactation.
Taib NA, Rahmat K
Adv Exp Med Biol 2020;1252:43-51. doi: 10.1007/978-3-030-41596-9_6. PMID: 32816261
Breast cancer and fat grafting: efficacy, safety and complications-a systematic review.
De Decker M, De Schrijver L, Thiessen F, Tondu T, Van Goethem M, Tjalma WA
Eur J Obstet Gynecol Reprod Biol 2016 Dec;207:100-108. Epub 2016 Oct 28 doi: 10.1016/j.ejogrb.2016.10.032. PMID: 27835828
Aluminium and the human breast.
Darbre PD
Morphologie 2016 Jun;100(329):65-74. Epub 2016 Mar 17 doi: 10.1016/j.morpho.2016.02.001. PMID: 26997127
Human gross cyst breast disease and cystic fluid: bio-molecular, morphological, and clinical studies.
Mannello F, Tonti GA, Papa S
Breast Cancer Res Treat 2006 May;97(2):115-29. Epub 2005 Dec 6 doi: 10.1007/s10549-005-9110-y. PMID: 16331347
Approach to a lump in the breast: a regional perspective.
Cheung KL, Lam TP
Asian J Surg 2005 Jan;28(1):65-70. doi: 10.1016/S1015-9584(09)60264-5. PMID: 15691804

Diagnosis

Galactorrhea and Galactocele after Breast Augmentation: Diagnosis and Treatment Algorithm.
Simão TS
Plast Reconstr Surg 2021 May 1;147(5):915e-916e. doi: 10.1097/PRS.0000000000007870. PMID: 33885442
Breast cyst aspiration.
Ponka D, Baddar F
Can Fam Physician 2012 Nov;58(11):1240. PMID: 23152464Free PMC Article
Approach to a lump in the breast: a regional perspective.
Cheung KL, Lam TP
Asian J Surg 2005 Jan;28(1):65-70. doi: 10.1016/S1015-9584(09)60264-5. PMID: 15691804
Breast cyst aspiration.
Lucas JH, Cone DL
Am Fam Physician 2003 Nov 15;68(10):1983-6. PMID: 14655807
Steroid biochemistry and categorization of breast cyst fluid: relation to breast cancer risk.
Angeli A, Dogliotti L, Naldoni C, Orlandi F, Puligheddu B, Caraci P, Bucchi L, Torta M, Bruzzi P
J Steroid Biochem Mol Biol 1994 Jun;49(4-6):333-9. doi: 10.1016/0960-0760(94)90276-3. PMID: 8043497

Therapy

Galactorrhea and Galactocele after Breast Augmentation: Diagnosis and Treatment Algorithm.
Simão TS
Plast Reconstr Surg 2021 May 1;147(5):915e-916e. doi: 10.1097/PRS.0000000000007870. PMID: 33885442
Breast cancer and fat grafting: efficacy, safety and complications-a systematic review.
De Decker M, De Schrijver L, Thiessen F, Tondu T, Van Goethem M, Tjalma WA
Eur J Obstet Gynecol Reprod Biol 2016 Dec;207:100-108. Epub 2016 Oct 28 doi: 10.1016/j.ejogrb.2016.10.032. PMID: 27835828
Aluminium and the human breast.
Darbre PD
Morphologie 2016 Jun;100(329):65-74. Epub 2016 Mar 17 doi: 10.1016/j.morpho.2016.02.001. PMID: 26997127
Aluminium and breast cancer: Sources of exposure, tissue measurements and mechanisms of toxicological actions on breast biology.
Darbre PD, Mannello F, Exley C
J Inorg Biochem 2013 Nov;128:257-61. Epub 2013 Jul 13 doi: 10.1016/j.jinorgbio.2013.07.005. PMID: 23899626
Breast cyst aspiration.
Ponka D, Baddar F
Can Fam Physician 2012 Nov;58(11):1240. PMID: 23152464Free PMC Article

Prognosis

Surgery for giant tumours of the breast: a 15 year review.
Daya M, Balakrishnan T
S Afr J Surg 2018 Sep;56(3):9-15. PMID: 30264936
Complications of Fat Transfer for Breast Augmentation.
Kontoes P, Gounnaris G
Aesthetic Plast Surg 2017 Oct;41(5):1078-1082. Epub 2017 Jun 22 doi: 10.1007/s00266-017-0911-2. PMID: 28643006
Human gross cyst breast disease and cystic fluid: bio-molecular, morphological, and clinical studies.
Mannello F, Tonti GA, Papa S
Breast Cancer Res Treat 2006 May;97(2):115-29. Epub 2005 Dec 6 doi: 10.1007/s10549-005-9110-y. PMID: 16331347
Cytological and biochemical studies of breast cyst fluid.
Tsung JS, Wang TY, Wang SM, Yang PS
Breast 2005 Feb;14(1):37-41. doi: 10.1016/j.breast.2004.09.006. PMID: 15695079
Risk of breast cancer in women with breast cysts.
Devitt JE, To T, Miller AB
CMAJ 1992 Jul 1;147(1):45-9. PMID: 1393887Free PMC Article

Clinical prediction guides

Breast density in dedicated breast computed tomography: Proposal of a classification system and interreader reliability.
Wieler J, Berger N, Frauenfelder T, Marcon M, Boss A
Medicine (Baltimore) 2021 May 7;100(18):e25844. doi: 10.1097/MD.0000000000025844. PMID: 33950998Free PMC Article
Breast Cyst Fluid Analysis Correlations with Speed of Sound Using Transmission Ultrasound.
Malik BH, Klock JC
Acad Radiol 2019 Jan;26(1):76-85. Epub 2018 Jun 7 doi: 10.1016/j.acra.2018.03.027. PMID: 29887398Free PMC Article
Aluminium and breast cancer: Sources of exposure, tissue measurements and mechanisms of toxicological actions on breast biology.
Darbre PD, Mannello F, Exley C
J Inorg Biochem 2013 Nov;128:257-61. Epub 2013 Jul 13 doi: 10.1016/j.jinorgbio.2013.07.005. PMID: 23899626
Human gross cyst breast disease and cystic fluid: bio-molecular, morphological, and clinical studies.
Mannello F, Tonti GA, Papa S
Breast Cancer Res Treat 2006 May;97(2):115-29. Epub 2005 Dec 6 doi: 10.1007/s10549-005-9110-y. PMID: 16331347
Risk of breast cancer in women with breast cysts.
Devitt JE, To T, Miller AB
CMAJ 1992 Jul 1;147(1):45-9. PMID: 1393887Free PMC Article

Recent systematic reviews

The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials.
Sharifi M, Nourani N, Sanaie S, Hamedeyazdan S
BMC Complement Med Ther 2024 Feb 15;24(1):89. doi: 10.1186/s12906-024-04378-5. PMID: 38360611Free PMC Article
Galactorrhea/Galactocele After Breast Augmentation: A Systematic Review.
Sharma SC, Basu NN
Ann Plast Surg 2021 Jan;86(1):115-120. doi: 10.1097/SAP.0000000000002290. PMID: 32079808
Complications after Breast Augmentation with Fat Grafting: A Systematic Review.
Ørholt M, Larsen A, Hemmingsen MN, Mirian C, Zocchi ML, Vester-Glowinski PV, Herly M
Plast Reconstr Surg 2020 Mar;145(3):530e-537e. doi: 10.1097/PRS.0000000000006569. PMID: 32097306
Breast cancer and fat grafting: efficacy, safety and complications-a systematic review.
De Decker M, De Schrijver L, Thiessen F, Tondu T, Van Goethem M, Tjalma WA
Eur J Obstet Gynecol Reprod Biol 2016 Dec;207:100-108. Epub 2016 Oct 28 doi: 10.1016/j.ejogrb.2016.10.032. PMID: 27835828
Review of complex breast cysts: implications for cancer detection and clinical practice.
Houssami N, Irwig L, Ung O
ANZ J Surg 2005 Dec;75(12):1080-5. doi: 10.1111/j.1445-2197.2005.03608.x. PMID: 16398815

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