U.S. flag

An official website of the United States government


Send to:

Choose Destination

Disorder of optic nerve

MedGen UID:
Concept ID:
Disease or Syndrome
Synonyms: Cranial Nerve II Diseases; Cranial Nerve II Disorder; Lesion, Neural-Optical; Neural Optical Lesion; Neural-Optical Lesion; Neural-Optical Lesions; Neuropathy, Optic; Optic Nerve Disease; Optic Nerve Diseases; Optic Neuropathies; Optic Neuropathy; Second Cranial Nerve Diseases
SNOMED CT: Disorder of optic nerve (77157004); Optic neuropathy (77157004)


A non-neoplastic or neoplastic disorder affecting the optic nerve (second cranial nerve). [from NCI]

Professional guidelines


Banwell B, Bennett JL, Marignier R, Kim HJ, Brilot F, Flanagan EP, Ramanathan S, Waters P, Tenembaum S, Graves JS, Chitnis T, Brandt AU, Hemingway C, Neuteboom R, Pandit L, Reindl M, Saiz A, Sato DK, Rostasy K, Paul F, Pittock SJ, Fujihara K, Palace J
Lancet Neurol 2023 Mar;22(3):268-282. Epub 2023 Jan 24 doi: 10.1016/S1474-4422(22)00431-8. PMID: 36706773
Raoof N, Hoffmann J
Cephalalgia 2021 Apr;41(4):472-478. Epub 2021 Feb 25 doi: 10.1177/0333102421997093. PMID: 33631966Free PMC Article
Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, Marrie RA, Miller AE, Miller DH, Montalban X, Mowry EM, Sorensen PS, Tintoré M, Traboulsee AL, Trojano M, Uitdehaag BMJ, Vukusic S, Waubant E, Weinshenker BG, Reingold SC, Cohen JA
Lancet Neurol 2018 Feb;17(2):162-173. Epub 2017 Dec 21 doi: 10.1016/S1474-4422(17)30470-2. PMID: 29275977

Recent clinical studies


Grzybowski A, Holder GE
Acta Ophthalmol 2011 Aug;89(5):495-9. Epub 2010 Mar 16 doi: 10.1111/j.1755-3768.2009.01853.x. PMID: 20337605

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...