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Lupus erythematosus panniculitis

MedGen UID:
14589
Concept ID:
C0030327
Disease or Syndrome
Synonyms: Lupus Erythematosus Panniculitides; Lupus Erythematosus Panniculitis; Lupus Erythematosus Profundus; Lupus Panniculitides; Lupus Panniculitis; Lupus Profundus; Panniculitides, Lupus; Panniculitides, Lupus Erythematosus; Panniculitis, Lupus; Panniculitis, Lupus Erythematosus
SNOMED CT: Lupus erythematosus profundus (15084002); Lupus panniculitis (239888002)
 
Monarch Initiative: MONDO:0019561
Orphanet: ORPHA90285

Definition

A rare form of chronic cutaneous lupus erythematosus characterized by recurrent, indurated, erythematous plaques and subcutaneous nodules with normal overlying epidermis, occurring predominantly on the face, upper arms, trunk, buttocks, and thighs. The lesions can ulcerate and lead to scarring. Histological findings include lobular lymphocytic panniculitis, hyaline fat necrosis, mucin deposition, and calcification. The condition may be associated with discoid or systemic lupus erythematosus. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLupus erythematosus panniculitis
Follow this link to review classifications for Lupus erythematosus panniculitis in Orphanet.

Professional guidelines

PubMed

Correll CK, Miller DD, Maguiness SM
JAMA Dermatol 2020 May 1;156(5):566-569. doi: 10.1001/jamadermatol.2019.4984. PMID: 32049306Free PMC Article
Braunstein I, Werth VP
Dermatol Ther 2012 Mar-Apr;25(2):173-82. doi: 10.1111/j.1529-8019.2012.01489.x. PMID: 22741936Free PMC Article

Recent clinical studies

Etiology

Machan S, Rodríguez M, Alonso-Alonso R, Manso R, Pérez-Buira S, Borregón J, Rodríguez-Peralto JL, Cerroni L, Haro R, García C, García Toro E, Estrach T, García-Herrera A, Ferrer B, González-Cruz C, Segues N, Afonso-Martin JL, Peñate Y, Monteagudo C, Limeres-Gonzalez MÁ, González-Núñez MÁ, Torres MÁT, Cereceda L, Córdoba R, Piris MÁ, Requena L, María Rodríguez-Pinilla S
Leuk Lymphoma 2021 Sep;62(9):2130-2140. Epub 2021 May 8 doi: 10.1080/10428194.2021.1901098. PMID: 33966586
Correll CK, Miller DD, Maguiness SM
JAMA Dermatol 2020 May 1;156(5):566-569. doi: 10.1001/jamadermatol.2019.4984. PMID: 32049306Free PMC Article
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Verdier M, Anuardo P, Gormezano NWS, Romiti R, Campos LMA, Aikawa NE, Pereira RMR, Terreri MT, Magalhães CS, Ferreira JCOA, Silva MFC, Ferriani M, Sakamoto AP, Ferriani VPL, Centeville M, Sato J, Santos MC, Bonfá E, Silva CA
Adv Rheumatol 2019 Jan 18;59(1):3. doi: 10.1186/s42358-019-0049-9. PMID: 30658703
Sáenz-Corral CI, Vega-Memíje ME, Martínez-Luna E, Cuevas-González JC, Rodríguez-Carreón AA, de la Rosa JJ, Del Muro Fde J, Avalos-Díaz E
Int J Clin Exp Pathol 2015;8(6):7260-5. Epub 2015 Jun 1 PMID: 26261624Free PMC Article

Diagnosis

Machan S, Rodríguez M, Alonso-Alonso R, Manso R, Pérez-Buira S, Borregón J, Rodríguez-Peralto JL, Cerroni L, Haro R, García C, García Toro E, Estrach T, García-Herrera A, Ferrer B, González-Cruz C, Segues N, Afonso-Martin JL, Peñate Y, Monteagudo C, Limeres-Gonzalez MÁ, González-Núñez MÁ, Torres MÁT, Cereceda L, Córdoba R, Piris MÁ, Requena L, María Rodríguez-Pinilla S
Leuk Lymphoma 2021 Sep;62(9):2130-2140. Epub 2021 May 8 doi: 10.1080/10428194.2021.1901098. PMID: 33966586
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Fraga J, García-Díez A
Dermatol Clin 2008 Oct;26(4):453-63, vi. doi: 10.1016/j.det.2008.06.002. PMID: 18793977
Kündig TM, Trüeb RM, Krasovec M
Dermatology 1997;195(1):99-101. doi: 10.1159/000245706. PMID: 9267758
Peters MS, Su WP
Med Clin North Am 1989 Sep;73(5):1113-26. doi: 10.1016/s0025-7125(16)30622-8. PMID: 2671535

Therapy

Maeshima K, Abe T, Imada C, Ozaki T, Shibata H
Rheumatology (Oxford) 2024 Mar 1;63(3):e115-e117. doi: 10.1093/rheumatology/kead553. PMID: 37819922
Correll CK, Miller DD, Maguiness SM
JAMA Dermatol 2020 May 1;156(5):566-569. doi: 10.1001/jamadermatol.2019.4984. PMID: 32049306Free PMC Article
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Lueangarun S, Subpayasarn U, Tempark T
Int J Dermatol 2019 Feb;58(2):144-150. Epub 2018 Aug 3 doi: 10.1111/ijd.14155. PMID: 30074627
Callen JP
Australas J Dermatol 2006 Feb;47(1):13-27. doi: 10.1111/j.1440-0960.2006.00217.x. PMID: 16405478

Prognosis

Xu Q, Qiu Y, Lu Z, Yu H, Ling B, Li Y, Gu Y, Yao Z
Dermatol Ther 2022 Nov;35(11):e15825. Epub 2022 Sep 27 doi: 10.1111/dth.15825. PMID: 36100983
Zhao YK, Wang F, Chen WN, Xu R, Wang Z, Jiang YW, Luo DQ, Han JD
Medicine (Baltimore) 2016 Apr;95(16):e3429. doi: 10.1097/MD.0000000000003429. PMID: 27100438Free PMC Article
Summers TA Jr, Lehman MB, Barner R, Royer MC
Adv Anat Pathol 2009 Jan;16(1):56-61. doi: 10.1097/PAP.0b013e3181915ff7. PMID: 19098467
Callen JP
Australas J Dermatol 2006 Feb;47(1):13-27. doi: 10.1111/j.1440-0960.2006.00217.x. PMID: 16405478
Peters MS, Su WP
Med Clin North Am 1989 Sep;73(5):1113-26. doi: 10.1016/s0025-7125(16)30622-8. PMID: 2671535

Clinical prediction guides

Machan S, Rodríguez M, Alonso-Alonso R, Manso R, Pérez-Buira S, Borregón J, Rodríguez-Peralto JL, Cerroni L, Haro R, García C, García Toro E, Estrach T, García-Herrera A, Ferrer B, González-Cruz C, Segues N, Afonso-Martin JL, Peñate Y, Monteagudo C, Limeres-Gonzalez MÁ, González-Núñez MÁ, Torres MÁT, Cereceda L, Córdoba R, Piris MÁ, Requena L, María Rodríguez-Pinilla S
Leuk Lymphoma 2021 Sep;62(9):2130-2140. Epub 2021 May 8 doi: 10.1080/10428194.2021.1901098. PMID: 33966586
Correll CK, Miller DD, Maguiness SM
JAMA Dermatol 2020 May 1;156(5):566-569. doi: 10.1001/jamadermatol.2019.4984. PMID: 32049306Free PMC Article
Verdier M, Anuardo P, Gormezano NWS, Romiti R, Campos LMA, Aikawa NE, Pereira RMR, Terreri MT, Magalhães CS, Ferreira JCOA, Silva MFC, Ferriani M, Sakamoto AP, Ferriani VPL, Centeville M, Sato J, Santos MC, Bonfá E, Silva CA
Adv Rheumatol 2019 Jan 18;59(1):3. doi: 10.1186/s42358-019-0049-9. PMID: 30658703
Guissa VR, Trudes G, Jesus AA, Aikawa NE, Romiti R, Silva CA
Acta Reumatol Port 2012 Jan-Mar;37(1):82-5. PMID: 22781517
White WL, Wieselthier JS, Hitchcock MG
Semin Cutan Med Surg 1996 Dec;15(4):278-99. doi: 10.1016/s1085-5629(96)80042-3. PMID: 9069596

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