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Pathological gambling

MedGen UID:
14632
Concept ID:
C0030662
Mental or Behavioral Dysfunction
Synonym: Gambling, pathologic
SNOMED CT: Pathological gambling disorder (18085000); Gambling disorder (18085000); Compulsive gambling (18085000)
 
Monarch Initiative: MONDO:0011662
OMIM®: 606349

Definition

Pathologic gambling is defined as a chronic and progressive failure to resist impulses to gamble accompanied by gambling behavior that compromises or damages personal, family, or vocational pursuits. The prevalence of pathologic gambling in the adult American population is estimated to be between 1 and 3% (review by Eisen et al., 1998). Comings et al. (2001) noted that some form of gambling is legal in all but 2 states in the U.S., and gambling on the Internet is available to anyone with a computer regardless of the local laws. They stated that as access to gambling has increased, there has been a corresponding increase in the frequency of addiction to gambling, known as pathologic gambling. [from OMIM]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPathological gambling

Professional guidelines

PubMed

Aboujaoude E, Salame WO
CNS Drugs 2016 Aug;30(8):719-33. doi: 10.1007/s40263-016-0373-0. PMID: 27401883
Winslow M, Cheok C, Subramaniam M
Addiction 2015 Sep;110(9):1383-7. Epub 2015 May 6 doi: 10.1111/add.12931. PMID: 25944124
Leung KS, Cottler LB
Curr Opin Psychiatry 2009 Jan;22(1):69-74. doi: 10.1097/YCO.0b013e32831575d9. PMID: 19122538

Recent clinical studies

Etiology

Chee TT, Lui YS
J Gambl Stud 2021 Sep;37(3):927-945. Epub 2021 Feb 1 doi: 10.1007/s10899-021-10012-7. PMID: 33521910
Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article
Erbas B, Buchner UG
Dtsch Arztebl Int 2012 Mar;109(10):173-9. Epub 2012 Mar 9 doi: 10.3238/arztebl.2012.0173. PMID: 22470406Free PMC Article
Blaszczynski A, Nower L
Addiction 2002 May;97(5):487-99. doi: 10.1046/j.1360-0443.2002.00015.x. PMID: 12033650
Allcock CC
Aust N Z J Psychiatry 1986 Sep;20(3):259-65. doi: 10.3109/00048678609158874. PMID: 3541888

Diagnosis

Zou Z, Wang H, d'Oleire Uquillas F, Wang X, Ding J, Chen H
Adv Exp Med Biol 2017;1010:21-41. doi: 10.1007/978-981-10-5562-1_2. PMID: 29098666
Robbins TW, Clark L
Curr Opin Neurobiol 2015 Feb;30:66-72. Epub 2014 Sep 26 doi: 10.1016/j.conb.2014.09.005. PMID: 25262209
Kuss DJ, Griffiths MD, Karila L, Billieux J
Curr Pharm Des 2014;20(25):4026-52. doi: 10.2174/13816128113199990617. PMID: 24001297
Potenza MN
Curr Opin Neurobiol 2013 Aug;23(4):660-7. Epub 2013 Mar 29 doi: 10.1016/j.conb.2013.03.004. PMID: 23541597Free PMC Article
Erbas B, Buchner UG
Dtsch Arztebl Int 2012 Mar;109(10):173-9. Epub 2012 Mar 9 doi: 10.3238/arztebl.2012.0173. PMID: 22470406Free PMC Article

Therapy

Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article
Cowlishaw S, Merkouris S, Dowling N, Anderson C, Jackson A, Thomas S
Cochrane Database Syst Rev 2012 Nov 14;11:CD008937. doi: 10.1002/14651858.CD008937.pub2. PMID: 23152266
Seppi K, Weintraub D, Coelho M, Perez-Lloret S, Fox SH, Katzenschlager R, Hametner EM, Poewe W, Rascol O, Goetz CG, Sampaio C
Mov Disord 2011 Oct;26 Suppl 3(0 3):S42-80. doi: 10.1002/mds.23884. PMID: 22021174Free PMC Article
Hollander E, Buchalter AJ, DeCaria CM
Psychiatr Clin North Am 2000 Sep;23(3):629-42. doi: 10.1016/s0193-953x(05)70185-4. PMID: 10986732
Hollander E, Rosen J
J Psychopharmacol 2000;14(2 Suppl 1):S39-44. doi: 10.1177/02698811000142S106. PMID: 10888030

Prognosis

Kramer MP, Peterson R, Leary AV, Wilborn DD, Magri T, Dvorak RD
Psychol Rep 2022 Oct;125(5):2384-2399. Epub 2021 Jun 3 doi: 10.1177/00332941211022998. PMID: 34080886
Xuan B, Li P, Yang L, Li M, Zhou J
Adv Exp Med Biol 2017;1010:133-168. doi: 10.1007/978-981-10-5562-1_8. PMID: 29098672
Sun YK, Sun Y, Lin X, Lu L, Shi J
Adv Exp Med Biol 2017;1010:73-89. doi: 10.1007/978-981-10-5562-1_5. PMID: 29098669
Tavares H
Addiction 2014 Dec;109(12):1972-6. Epub 2014 May 23 doi: 10.1111/add.12560. PMID: 24851676
Hodgins DC, Stea JN, Grant JE
Lancet 2011 Nov 26;378(9806):1874-84. Epub 2011 May 18 doi: 10.1016/S0140-6736(10)62185-X. PMID: 21600645

Clinical prediction guides

de Ridder B, Deighton RM
J Gambl Stud 2022 Sep;38(3):1059-1073. Epub 2021 Jul 15 doi: 10.1007/s10899-021-10059-6. PMID: 34268668
Xuan B, Li P, Yang L, Li M, Zhou J
Adv Exp Med Biol 2017;1010:133-168. doi: 10.1007/978-981-10-5562-1_8. PMID: 29098672
Sun YK, Sun Y, Lin X, Lu L, Shi J
Adv Exp Med Biol 2017;1010:73-89. doi: 10.1007/978-981-10-5562-1_5. PMID: 29098669
Chowdhury NS, Livesey EJ, Blaszczynski A, Harris JA
J Gambl Stud 2017 Dec;33(4):1213-1239. doi: 10.1007/s10899-017-9683-5. PMID: 28255940
Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article

Recent systematic reviews

Chowdhury NS, Livesey EJ, Blaszczynski A, Harris JA
J Gambl Stud 2017 Dec;33(4):1213-1239. doi: 10.1007/s10899-017-9683-5. PMID: 28255940
Cowlishaw S, Merkouris S, Chapman A, Radermacher H
J Subst Abuse Treat 2014 Feb;46(2):98-105. Epub 2013 Sep 24 doi: 10.1016/j.jsat.2013.08.019. PMID: 24074847
Kuss DJ, Griffiths MD, Karila L, Billieux J
Curr Pharm Des 2014;20(25):4026-52. doi: 10.2174/13816128113199990617. PMID: 24001297
Gyollai A, Griffiths MD, Barta C, Vereczkei A, Urbán R, Kun B, Kökönyei G, Székely A, Sasvári-Székely M, Blum K, Demetrovics Z
Curr Pharm Des 2014;20(25):3993-9. doi: 10.2174/13816128113199990626. PMID: 24001288
Conversano C, Marazziti D, Carmassi C, Baldini S, Barnabei G, Dell'Osso L
Harv Rev Psychiatry 2012 May-Jun;20(3):130-48. doi: 10.3109/10673229.2012.694318. PMID: 22716504

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