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Pathological gambling

MedGen UID:
14632
Concept ID:
C0030662
Mental or Behavioral Dysfunction
Synonym: Gambling, pathologic
SNOMED CT: Pathological gambling disorder (18085000); Gambling disorder (18085000); Compulsive gambling (18085000)
 
Monarch Initiative: MONDO:0011662
OMIM®: 606349

Definition

Pathologic gambling is defined as a chronic and progressive failure to resist impulses to gamble accompanied by gambling behavior that compromises or damages personal, family, or vocational pursuits. The prevalence of pathologic gambling in the adult American population is estimated to be between 1 and 3% (review by Eisen et al., 1998). Comings et al. (2001) noted that some form of gambling is legal in all but 2 states in the U.S., and gambling on the Internet is available to anyone with a computer regardless of the local laws. They stated that as access to gambling has increased, there has been a corresponding increase in the frequency of addiction to gambling, known as pathologic gambling. [from OMIM]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPathological gambling

Professional guidelines

PubMed

Aboujaoude E, Salame WO
CNS Drugs 2016 Aug;30(8):719-33. doi: 10.1007/s40263-016-0373-0. PMID: 27401883
van den Brink W
Curr Drug Abuse Rev 2012 Mar;5(1):3-31. doi: 10.2174/1874473711205010003. PMID: 22126708
Olive MF, Cleva RM, Kalivas PW, Malcolm RJ
Pharmacol Biochem Behav 2012 Feb;100(4):801-10. Epub 2011 Apr 22 doi: 10.1016/j.pbb.2011.04.015. PMID: 21536062Free PMC Article

Recent clinical studies

Etiology

Moreira D, Azeredo A, Dias P
J Gambl Stud 2023 Jun;39(2):483-511. Epub 2023 Mar 8 doi: 10.1007/s10899-023-10195-1. PMID: 36884150Free PMC Article
Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article
Erbas B, Buchner UG
Dtsch Arztebl Int 2012 Mar;109(10):173-9. Epub 2012 Mar 9 doi: 10.3238/arztebl.2012.0173. PMID: 22470406Free PMC Article
Blaszczynski A, Nower L
Addiction 2002 May;97(5):487-99. doi: 10.1046/j.1360-0443.2002.00015.x. PMID: 12033650
Allcock CC
Aust N Z J Psychiatry 1986 Sep;20(3):259-65. doi: 10.3109/00048678609158874. PMID: 3541888

Diagnosis

Moreira D, Azeredo A, Dias P
J Gambl Stud 2023 Jun;39(2):483-511. Epub 2023 Mar 8 doi: 10.1007/s10899-023-10195-1. PMID: 36884150Free PMC Article
Zou Z, Wang H, d'Oleire Uquillas F, Wang X, Ding J, Chen H
Adv Exp Med Biol 2017;1010:21-41. doi: 10.1007/978-981-10-5562-1_2. PMID: 29098666
Robbins TW, Clark L
Curr Opin Neurobiol 2015 Feb;30:66-72. Epub 2014 Sep 26 doi: 10.1016/j.conb.2014.09.005. PMID: 25262209
Potenza MN
Curr Opin Neurobiol 2013 Aug;23(4):660-7. Epub 2013 Mar 29 doi: 10.1016/j.conb.2013.03.004. PMID: 23541597Free PMC Article
Erbas B, Buchner UG
Dtsch Arztebl Int 2012 Mar;109(10):173-9. Epub 2012 Mar 9 doi: 10.3238/arztebl.2012.0173. PMID: 22470406Free PMC Article

Therapy

Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article
Aboujaoude E, Salame WO
CNS Drugs 2016 Aug;30(8):719-33. doi: 10.1007/s40263-016-0373-0. PMID: 27401883
Seppi K, Weintraub D, Coelho M, Perez-Lloret S, Fox SH, Katzenschlager R, Hametner EM, Poewe W, Rascol O, Goetz CG, Sampaio C
Mov Disord 2011 Oct;26 Suppl 3(0 3):S42-80. doi: 10.1002/mds.23884. PMID: 22021174Free PMC Article
Hollander E, Buchalter AJ, DeCaria CM
Psychiatr Clin North Am 2000 Sep;23(3):629-42. doi: 10.1016/s0193-953x(05)70185-4. PMID: 10986732
Hollander E, Rosen J
J Psychopharmacol 2000;14(2 Suppl 1):S39-44. doi: 10.1177/02698811000142S106. PMID: 10888030

Prognosis

Shen W, Liu H, Xie X, Liu H, Zhou W
Adv Exp Med Biol 2017;1010:169-202. doi: 10.1007/978-981-10-5562-1_9. PMID: 29098673
Xuan B, Li P, Yang L, Li M, Zhou J
Adv Exp Med Biol 2017;1010:133-168. doi: 10.1007/978-981-10-5562-1_8. PMID: 29098672
Nautiyal KM, Okuda M, Hen R, Blanco C
Ann N Y Acad Sci 2017 Apr;1394(1):106-127. doi: 10.1111/nyas.13356. PMID: 28486792Free PMC Article
Ashley LL, Boehlke KK
J Psychoactive Drugs 2012 Jan-Mar;44(1):27-37. doi: 10.1080/02791072.2012.662078. PMID: 22641963
Hodgins DC, Stea JN, Grant JE
Lancet 2011 Nov 26;378(9806):1874-84. Epub 2011 May 18 doi: 10.1016/S0140-6736(10)62185-X. PMID: 21600645

Clinical prediction guides

Shen W, Liu H, Xie X, Liu H, Zhou W
Adv Exp Med Biol 2017;1010:169-202. doi: 10.1007/978-981-10-5562-1_9. PMID: 29098673
Xuan B, Li P, Yang L, Li M, Zhou J
Adv Exp Med Biol 2017;1010:133-168. doi: 10.1007/978-981-10-5562-1_8. PMID: 29098672
Chowdhury NS, Livesey EJ, Blaszczynski A, Harris JA
J Gambl Stud 2017 Dec;33(4):1213-1239. doi: 10.1007/s10899-017-9683-5. PMID: 28255940
Heiden P, Heinz A, Romanczuk-Seiferth N
Eur J Neurosci 2017 Jan;45(1):67-72. Epub 2016 Oct 1 doi: 10.1111/ejn.13396. PMID: 27623191Free PMC Article
Vachon DD, Bagby RM
Psychol Assess 2009 Dec;21(4):608-15. doi: 10.1037/a0016846. PMID: 19947793

Recent systematic reviews

Eriksen JW, Fiskaali A, Zachariae R, Wellnitz KB, Oernboel E, Stenbro AW, Marcussen T, Petersen MW
J Behav Addict 2023 Oct 5;12(3):613-630. Epub 2023 Jul 14 doi: 10.1556/2006.2023.00034. PMID: 37450372Free PMC Article
Moreira D, Azeredo A, Dias P
J Gambl Stud 2023 Jun;39(2):483-511. Epub 2023 Mar 8 doi: 10.1007/s10899-023-10195-1. PMID: 36884150Free PMC Article
Chowdhury NS, Livesey EJ, Blaszczynski A, Harris JA
J Gambl Stud 2017 Dec;33(4):1213-1239. doi: 10.1007/s10899-017-9683-5. PMID: 28255940
Kuss DJ, Griffiths MD, Karila L, Billieux J
Curr Pharm Des 2014;20(25):4026-52. doi: 10.2174/13816128113199990617. PMID: 24001297
Gyollai A, Griffiths MD, Barta C, Vereczkei A, Urbán R, Kun B, Kökönyei G, Székely A, Sasvári-Székely M, Blum K, Demetrovics Z
Curr Pharm Des 2014;20(25):3993-9. doi: 10.2174/13816128113199990626. PMID: 24001288

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