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Benign Lung Hilum Neoplasm

MedGen UID:
146341
•Concept ID:
C0685024
•
Neoplastic Process
Synonyms: Benign Hilar Lung Neoplasm; Benign Hilar Lung Tumor; Benign Lung Hilum Tumor; Benign neoplasm of hilus of lung
SNOMED CT: Benign neoplasm of hilus of lung (92134005)

Definition

A neoplasm that arises from the hilar region of lung and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Lung Hilum Neoplasm

Recent clinical studies

Etiology

Radial-probe endobronchial ultrasound outcomes in the investigation of peripheral pulmonary lesions: a New Zealand perspective.
Good WR, Christensen PM, Herath S, Dawkins P, Yap E
Intern Med J 2018 Dec;48(12):1481-1487. doi: 10.1111/imj.14070. PMID: 30091278
Radial probe endobronchial ultrasound: factors influencing visualization yield of peripheral pulmonary lesions.
Tay JH, Irving L, Antippa P, Steinfort DP
Respirology 2013 Jan;18(1):185-90. doi: 10.1111/j.1440-1843.2012.02276.x. PMID: 23035636
Lung hilar Ga-67 uptake in patients with lymphoma following chemotherapy.
Gunay EC, Salanci BV, Barista I, Caner B
Ann Nucl Med 2004 Jul;18(5):391-7. doi: 10.1007/BF02984482. PMID: 15462401
Diagnostic yield of fiberoptic bronchoscopy in evaluating solitary pulmonary nodules.
Baaklini WA, Reinoso MA, Gorin AB, Sharafkaneh A, Manian P
Chest 2000 Apr;117(4):1049-54. doi: 10.1378/chest.117.4.1049. PMID: 10767238
Imaging of the pulmonary hilum: a prospective comparative study in patients with lung cancer.
Glazer GM, Gross BH, Aisen AM, Quint LE, Francis IR, Orringer MB
AJR Am J Roentgenol 1985 Aug;145(2):245-8. doi: 10.2214/ajr.145.2.245. PMID: 3875219

Diagnosis

Ultrathin Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions: A Meta-Analysis.
Kim SH, Kim J, Pak K, Eom JS
Respiration 2023;102(1):34-45. Epub 2022 Nov 22 doi: 10.1159/000527362. PMID: 36412624Free PMC Article
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Radial-probe endobronchial ultrasound outcomes in the investigation of peripheral pulmonary lesions: a New Zealand perspective.
Good WR, Christensen PM, Herath S, Dawkins P, Yap E
Intern Med J 2018 Dec;48(12):1481-1487. doi: 10.1111/imj.14070. PMID: 30091278
Radial probe endobronchial ultrasound: factors influencing visualization yield of peripheral pulmonary lesions.
Tay JH, Irving L, Antippa P, Steinfort DP
Respirology 2013 Jan;18(1):185-90. doi: 10.1111/j.1440-1843.2012.02276.x. PMID: 23035636
EUS-FNA of recurrent postoperative extraluminal and metastatic malignancy.
Dewitt J, Ghorai S, Kahi C, Leblanc J, McHenry L, Chappo J, Cramer H, McGreevy K, Chriswell M, Sherman S
Gastrointest Endosc 2003 Oct;58(4):542-8. doi: 10.1067/s0016-5107(03)01872-8. PMID: 14520287

Therapy

Radial-probe endobronchial ultrasound outcomes in the investigation of peripheral pulmonary lesions: a New Zealand perspective.
Good WR, Christensen PM, Herath S, Dawkins P, Yap E
Intern Med J 2018 Dec;48(12):1481-1487. doi: 10.1111/imj.14070. PMID: 30091278
Lung hilar Ga-67 uptake in patients with lymphoma following chemotherapy.
Gunay EC, Salanci BV, Barista I, Caner B
Ann Nucl Med 2004 Jul;18(5):391-7. doi: 10.1007/BF02984482. PMID: 15462401
Narrow time-window dual-point 18F-FDG PET for the diagnosis of thoracic malignancy.
Conrad GR, Sinha P
Nucl Med Commun 2003 Nov;24(11):1129-37. doi: 10.1097/00006231-200311000-00002. PMID: 14569166
Transthoracic needle biopsy of the hilum and mediastinum.
Westcott JL
J Thorac Imaging 1987 Apr;2(2):41-8. doi: 10.1097/00005382-198704000-00009. PMID: 3599147

Prognosis

Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Radial-probe endobronchial ultrasound outcomes in the investigation of peripheral pulmonary lesions: a New Zealand perspective.
Good WR, Christensen PM, Herath S, Dawkins P, Yap E
Intern Med J 2018 Dec;48(12):1481-1487. doi: 10.1111/imj.14070. PMID: 30091278
Usefulness of endobronchial ultrasound-guided transbronchial needle aspiration in distinguishing sarcoidosis from recurrent cancer in patients with lymphadenopathy after surgery.
Minami D, Takigawa N, Hayakawa H, Mizuta M, Kudo K, Uchida K, Ichihara E, Sato A, Hotta K, Tabata M, Tanimoto M, Kiura K
Jpn J Clin Oncol 2013 Nov;43(11):1110-4. Epub 2013 Aug 29 doi: 10.1093/jjco/hyt123. PMID: 23997237
Radial probe endobronchial ultrasound: factors influencing visualization yield of peripheral pulmonary lesions.
Tay JH, Irving L, Antippa P, Steinfort DP
Respirology 2013 Jan;18(1):185-90. doi: 10.1111/j.1440-1843.2012.02276.x. PMID: 23035636
Vascular image patterns of lymph nodes for the prediction of metastatic disease during EBUS-TBNA for mediastinal staging of lung cancer.
Nakajima T, Anayama T, Shingyoji M, Kimura H, Yoshino I, Yasufuku K
J Thorac Oncol 2012 Jun;7(6):1009-14. doi: 10.1097/JTO.0b013e31824cbafa. PMID: 22525556

Clinical prediction guides

Ultrathin Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions: A Meta-Analysis.
Kim SH, Kim J, Pak K, Eom JS
Respiration 2023;102(1):34-45. Epub 2022 Nov 22 doi: 10.1159/000527362. PMID: 36412624Free PMC Article
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Radial-probe endobronchial ultrasound outcomes in the investigation of peripheral pulmonary lesions: a New Zealand perspective.
Good WR, Christensen PM, Herath S, Dawkins P, Yap E
Intern Med J 2018 Dec;48(12):1481-1487. doi: 10.1111/imj.14070. PMID: 30091278
A rare case of pulmonary sclerosing hemagioma with lymph node metastasis and review of the literature.
Xu HM, Zhang G
Int J Clin Exp Pathol 2015;8(7):8619-23. Epub 2015 Jul 1 PMID: 26339444Free PMC Article
Radial probe endobronchial ultrasound: factors influencing visualization yield of peripheral pulmonary lesions.
Tay JH, Irving L, Antippa P, Steinfort DP
Respirology 2013 Jan;18(1):185-90. doi: 10.1111/j.1440-1843.2012.02276.x. PMID: 23035636

Recent systematic reviews

Ultrathin Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions: A Meta-Analysis.
Kim SH, Kim J, Pak K, Eom JS
Respiration 2023;102(1):34-45. Epub 2022 Nov 22 doi: 10.1159/000527362. PMID: 36412624Free PMC Article

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