U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Peritonitis

MedGen UID:
14697
Concept ID:
C0031154
Pathologic Function
Synonym: Peritoneal inflammation
SNOMED CT: Peritonitis (48661000)
 
HPO: HP:0002586
Monarch Initiative: MONDO:0004522

Definition

Inflammation of the peritoneum. [from HPO]

Conditions with this feature

Familial Mediterranean fever
MedGen UID:
45811
Concept ID:
C0031069
Disease or Syndrome
Familial Mediterranean fever (FMF) is divided into two phenotypes: type 1 and type 2. FMF type 1 is characterized by recurrent short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and, rarely, pericarditis and meningitis. The symptoms and severity vary among affected individuals, sometimes even among members of the same family. Amyloidosis, which can lead to renal failure, is the most severe complication, if untreated. FMF type 2 is characterized by amyloidosis as the first clinical manifestation of FMF in an otherwise asymptomatic individual.
Familial Mediterranean fever, autosomal dominant
MedGen UID:
341987
Concept ID:
C1851347
Disease or Syndrome
Familial Mediterranean fever (FMF) is divided into two phenotypes: type 1 and type 2. FMF type 1 is characterized by recurrent short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and, rarely, pericarditis and meningitis. The symptoms and severity vary among affected individuals, sometimes even among members of the same family. Amyloidosis, which can lead to renal failure, is the most severe complication, if untreated. FMF type 2 is characterized by amyloidosis as the first clinical manifestation of FMF in an otherwise asymptomatic individual.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2
MedGen UID:
383869
Concept ID:
C1856245
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Complement factor b deficiency
MedGen UID:
816280
Concept ID:
C3809950
Disease or Syndrome
Megacystis-microcolon-intestinal hypoperistalsis syndrome 2
MedGen UID:
1788773
Concept ID:
C5543476
Disease or Syndrome
Megacystis-microcolon-intestinal hypoperistalsis syndrome-2 (MMIHS2) is characterized by prenatal bladder enlargement, neonatal functional gastrointestinal obstruction, and chronic dependence on total parenteral nutrition and urinary catheterization. The majority of cases have a fatal outcome due to malnutrition and sepsis, followed by multiorgan failure (summary by Wang et al., 2019). For a discussion of genetic heterogeneity of MMIHS, see 249210.
Liver disease, severe congenital
MedGen UID:
1823968
Concept ID:
C5774195
Disease or Syndrome
Severe congenital liver disease (SCOLIV) is an autosomal recessive disorder characterized by the onset of progressive hepatic dysfunction usually in the first years of life. Affected individuals show feeding difficulties with failure to thrive and features such as jaundice, hepatomegaly, and abdominal distension. Laboratory workup is consistent with hepatic insufficiency and may also show coagulation defects, anemia, or metabolic disturbances. Cirrhosis and hypernodularity are commonly observed on liver biopsy. Many patients die of liver failure in early childhood (Moreno Traspas et al., 2022).

Professional guidelines

PubMed

Tapper EB, Parikh ND
JAMA 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031Free PMC Article
Khan S, Linganna M
Cleve Clin J Med 2023 Apr 3;90(4):209-213. doi: 10.3949/ccjm.90a.22028. PMID: 37011958
Smith A, Baumgartner K, Bositis C
Am Fam Physician 2019 Dec 15;100(12):759-770. PMID: 31845776

Recent clinical studies

Etiology

Li PK, Chow KM, Cho Y, Fan S, Figueiredo AE, Harris T, Kanjanabuch T, Kim YL, Madero M, Malyszko J, Mehrotra R, Okpechi IG, Perl J, Piraino B, Runnegar N, Teitelbaum I, Wong JK, Yu X, Johnson DW
Perit Dial Int 2022 Mar;42(2):110-153. doi: 10.1177/08968608221080586. PMID: 35264029
Al Sahlawi M, Zhao J, McCullough K, Fuller DS, Boudville N, Ito Y, Kanjanabuch T, Nessim SJ, Piraino BM, Pisoni RL, Teitelbaum I, Woodrow G, Kawanishi H, Johnson DW, Perl J
Am J Kidney Dis 2022 Jan;79(1):45-55.e1. Epub 2021 May 28 doi: 10.1053/j.ajkd.2021.03.022. PMID: 34052357
Pimentel R, Gregório C, Figueiredo P
Acta Gastroenterol Belg 2021 Apr-Jun;84(2):333-342. doi: 10.51821/84.2.333. PMID: 34217185
Nascimbeni R, Amato A, Cirocchi R, Serventi A, Laghi A, Bellini M, Tellan G, Zago M, Scarpignato C, Binda GA
Tech Coloproctol 2021 Feb;25(2):153-165. Epub 2020 Nov 5 doi: 10.1007/s10151-020-02346-y. PMID: 33155148Free PMC Article
Hasibeder W, Halabi M
Minerva Anestesiol 2014 Apr;80(4):470-81. Epub 2013 Sep 3 PMID: 24002461

Diagnosis

Napolitano LM
Semin Respir Crit Care Med 2022 Feb;43(1):10-27. Epub 2022 Feb 16 doi: 10.1055/s-0041-1741053. PMID: 35172355
Montravers P, Assadi M, Gouel-Cheron A
Curr Opin Crit Care 2021 Apr 1;27(2):201-207. doi: 10.1097/MCC.0000000000000805. PMID: 33395082
Szeto CC, Li PK
Clin J Am Soc Nephrol 2019 Jul 5;14(7):1100-1105. Epub 2019 May 8 doi: 10.2215/CJN.14631218. PMID: 31068338Free PMC Article
Ross JT, Matthay MA, Harris HW
BMJ 2018 Jun 18;361:k1407. doi: 10.1136/bmj.k1407. PMID: 29914871Free PMC Article
Hasibeder W, Halabi M
Minerva Anestesiol 2014 Apr;80(4):470-81. Epub 2013 Sep 3 PMID: 24002461

Therapy

Jalava K, Sallinen V, Lampela H, Malmi H, Steinholt I, Augestad KM, Leppäniemi A, Mentula P
Lancet 2023 Oct 28;402(10412):1552-1561. Epub 2023 Sep 14 doi: 10.1016/S0140-6736(23)01311-9. PMID: 37717589
Tapper EB, Parikh ND
JAMA 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031Free PMC Article
Caraceni P, Vargas V, Solà E, Alessandria C, de Wit K, Trebicka J, Angeli P, Mookerjee RP, Durand F, Pose E, Krag A, Bajaj JS, Beuers U, Ginès P; Liverhope Consortium
Hepatology 2021 Sep;74(3):1660-1673. Epub 2021 Jun 7 doi: 10.1002/hep.31708. PMID: 33421158Free PMC Article
Coccolini F, Fugazzola P, Sartelli M, Cicuttin E, Sibilla MG, Leandro G, De' Angelis GL, Gaiani F, Di Mario F, Tomasoni M, Catena F, Ansaloni L
Acta Biomed 2018 Dec 17;89(9-S):119-134. doi: 10.23750/abm.v89i9-S.7905. PMID: 30561405Free PMC Article
Campbell D, Mudge DW, Craig JC, Johnson DW, Tong A, Strippoli GF
Cochrane Database Syst Rev 2017 Apr 8;4(4):CD004679. doi: 10.1002/14651858.CD004679.pub3. PMID: 28390069Free PMC Article

Prognosis

Ito Y, Tawada M, Tine S, Mizuno M, Suzuki Y, Katsuno T
Contrib Nephrol 2018;196:123-128. Epub 2018 Jul 24 doi: 10.1159/000485711. PMID: 30041216
Piraino B
Semin Dial 2017 Mar;30(2):158-163. Epub 2017 Jan 8 doi: 10.1111/sdi.12571. PMID: 28066919
Ndayizeye L, Ngarambe C, Smart B, Riviello R, Majyambere JP, Rickard J
Surgery 2016 Dec;160(6):1645-1656. Epub 2016 Oct 4 doi: 10.1016/j.surg.2016.08.036. PMID: 27712880
D'Souza N
BMJ Clin Evid 2011 Jan 7;2011 PMID: 21477397Free PMC Article
Jayanthi V, Probert CS, Sher KS, Wicks AC, Mayberry JF
Dig Dis 1993;11(1):36-44. doi: 10.1159/000171399. PMID: 8443955

Clinical prediction guides

Padeh S, Berkun Y
Curr Opin Rheumatol 2016 Sep;28(5):523-9. doi: 10.1097/BOR.0000000000000315. PMID: 27286236
Abraldes JG, Sarlieve P, Tandon P
Clin Liver Dis 2014 Nov;18(4):779-92. Epub 2014 Aug 21 doi: 10.1016/j.cld.2014.07.002. PMID: 25438283
Mueller S, Seitz HK, Rausch V
World J Gastroenterol 2014 Oct 28;20(40):14626-41. doi: 10.3748/wjg.v20.i40.14626. PMID: 25356026Free PMC Article
van den Heijkant TC, Aerts BA, Teijink JA, Buurman WA, Luyer MD
World J Gastroenterol 2013 Mar 7;19(9):1338-41. doi: 10.3748/wjg.v19.i9.1338. PMID: 23538325Free PMC Article
Ohmann C, Hau T
Hepatogastroenterology 1997 Jul-Aug;44(16):937-46. PMID: 9261581

Recent systematic reviews

Marcinkowski KA, Mehta V, Mercier R, Berghella V
Am J Obstet Gynecol MFM 2022 Jul;4(4):100643. Epub 2022 Apr 8 doi: 10.1016/j.ajogmf.2022.100643. PMID: 35405372
Pimentel R, Gregório C, Figueiredo P
Acta Gastroenterol Belg 2021 Apr-Jun;84(2):333-342. doi: 10.51821/84.2.333. PMID: 34217185
Htay H, Johnson DW, Wiggins KJ, Badve SV, Craig JC, Strippoli GF, Cho Y
Cochrane Database Syst Rev 2018 Oct 26;10(10):CD007554. doi: 10.1002/14651858.CD007554.pub3. PMID: 30362116Free PMC Article
Campbell D, Mudge DW, Craig JC, Johnson DW, Tong A, Strippoli GF
Cochrane Database Syst Rev 2017 Apr 8;4(4):CD004679. doi: 10.1002/14651858.CD004679.pub3. PMID: 28390069Free PMC Article
D'Souza N, Nugent K
BMJ Clin Evid 2014 Dec 8;2014 PMID: 25486014Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...