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Immune-complex glomerulonephritis

MedGen UID:
148168
•Concept ID:
C0744421
•
Disease or Syndrome
Synonyms: Immune complex glomerulonephritis; Immune Complex Glomerulonephritis; immune Complex glomerulonephritis; immune-complex glomerulonephritis
SNOMED CT: Immune-complex glomerulonephritis (123752003); Immune complex glomerulonephritis (123752003)
 
Monarch Initiative: MONDO:0003140

Definition

Inflammation of the glomeruli characterized by the accumulation of antibody-antigen immune complexes, resulting in glomerular damage and impaired kidney function. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmune-complex glomerulonephritis

Professional guidelines

PubMed

Current best practices and guidelines. Assessment and management of complications in infective endocarditis.
Sexton DJ, Spelman D
Cardiol Clin 2003 May;21(2):273-82, vii-viii. doi: 10.1016/s0733-8651(03)00031-6. PMID: 12874898
Current best practices and guidelines. Assessment and management of complications in infective endocarditis.
Sexton DJ, Spelman D
Infect Dis Clin North Am 2002 Jun;16(2):507-21, xii. doi: 10.1016/s0891-5520(01)00011-3. PMID: 12092484
Vitamin E treatment of focal segmental glomerulosclerosis: results of an open-label study.
Tahzib M, Frank R, Gauthier B, Valderrama E, Trachtman H
Pediatr Nephrol 1999 Oct;13(8):649-52. doi: 10.1007/s004670050674. PMID: 10502120

Recent clinical studies

Etiology

Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
Association between Opisthorchis viverrini Infection and Glomerular Disease in Thailand.
Tonsawan P, Intarak S, Sripa B, Puapairoj A, Sripa M, Sithithaworn P, Anutrakulchai S
Am J Nephrol 2022;53(2-3):199-206. Epub 2022 Feb 15 doi: 10.1159/000521780. PMID: 35168235
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article
Proliferative glomerulonephritis with monoclonal IgG deposits: a distinct entity mimicking immune-complex glomerulonephritis.
Nasr SH, Markowitz GS, Stokes MB, Seshan SV, Valderrama E, Appel GB, Aucouturier P, D'Agati VD
Kidney Int 2004 Jan;65(1):85-96. doi: 10.1111/j.1523-1755.2004.00365.x. PMID: 14675039
Bacterial arthritis.
Ho G Jr
Curr Opin Rheumatol 1992 Aug;4(4):509-15. PMID: 1503874

Diagnosis

Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
Association between Opisthorchis viverrini Infection and Glomerular Disease in Thailand.
Tonsawan P, Intarak S, Sripa B, Puapairoj A, Sripa M, Sithithaworn P, Anutrakulchai S
Am J Nephrol 2022;53(2-3):199-206. Epub 2022 Feb 15 doi: 10.1159/000521780. PMID: 35168235
Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine.
Santoriello D, Bomback AS, Kudose S, Batal I, Stokes MB, Canetta PA, Radhakrishnan J, Appel GB, D'Agati VD, Markowitz GS
Kidney Int 2021 Aug;100(2):440-446. Epub 2021 Apr 20 doi: 10.1016/j.kint.2021.03.029. PMID: 33857570
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article

Therapy

Recurrent disease after pediatric renal transplantation.
Nayak A, Ettenger R, Wesseling-Perry K
Pediatr Transplant 2024 May;28(3):e14676. doi: 10.1111/petr.14676. PMID: 38650536
Glomerular diseases after immune checkpoint inhibitors use: What do We know so far?
He X, Liu F, Jin Y, Fu H, Mao J
Ren Fail 2022 Dec;44(1):2046-2055. doi: 10.1080/0886022X.2022.2147439. PMID: 36420664Free PMC Article
Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
De novo lupus-like glomerulonephritis after pediatric non-kidney organ transplantation.
Farkas-Skiles CM, Ettenger RB, Zuckerman JE, Pearl M, Venick RS, Weng PL
Pediatr Nephrol 2022 Jan;37(1):153-161. Epub 2021 Jul 22 doi: 10.1007/s00467-021-05194-6. PMID: 34292379Free PMC Article
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304

Prognosis

Recurrent disease after pediatric renal transplantation.
Nayak A, Ettenger R, Wesseling-Perry K
Pediatr Transplant 2024 May;28(3):e14676. doi: 10.1111/petr.14676. PMID: 38650536
Glomerular diseases after immune checkpoint inhibitors use: What do We know so far?
He X, Liu F, Jin Y, Fu H, Mao J
Ren Fail 2022 Dec;44(1):2046-2055. doi: 10.1080/0886022X.2022.2147439. PMID: 36420664Free PMC Article
Association between Opisthorchis viverrini Infection and Glomerular Disease in Thailand.
Tonsawan P, Intarak S, Sripa B, Puapairoj A, Sripa M, Sithithaworn P, Anutrakulchai S
Am J Nephrol 2022;53(2-3):199-206. Epub 2022 Feb 15 doi: 10.1159/000521780. PMID: 35168235
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article
Proliferative glomerulonephritis with monoclonal IgG deposits: a distinct entity mimicking immune-complex glomerulonephritis.
Nasr SH, Markowitz GS, Stokes MB, Seshan SV, Valderrama E, Appel GB, Aucouturier P, D'Agati VD
Kidney Int 2004 Jan;65(1):85-96. doi: 10.1111/j.1523-1755.2004.00365.x. PMID: 14675039

Clinical prediction guides

Association between Opisthorchis viverrini Infection and Glomerular Disease in Thailand.
Tonsawan P, Intarak S, Sripa B, Puapairoj A, Sripa M, Sithithaworn P, Anutrakulchai S
Am J Nephrol 2022;53(2-3):199-206. Epub 2022 Feb 15 doi: 10.1159/000521780. PMID: 35168235
Renal effects of immune checkpoint inhibitors.
Izzedine H, Mateus C, Boutros C, Robert C, Rouvier P, Amoura Z, Mathian A
Nephrol Dial Transplant 2017 Jun 1;32(6):936-942. doi: 10.1093/ndt/gfw382. PMID: 28025384
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Immunopathological events initiated and maintained by pathogenic IgG autoantibodies in an experimental autoimmune kidney disease.
Barabas AZ, Cole CD, Lafreniere R, Weir DM
Autoimmunity 2012 Nov;45(7):495-509. Epub 2012 Aug 17 doi: 10.3109/08916934.2012.702812. PMID: 22816962
Hepatitis-B-associated glomerulonephritis: pathology, pathogenesis, and clinical course.
Venkataseshan VS, Lieberman K, Kim DU, Thung SN, Dikman S, D'Agati V, Susin M, Valderrama E, Gauthier B, Prakash A
Medicine (Baltimore) 1990 Jul;69(4):200-16. PMID: 2142748

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