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Radiation-Related Malignant Neoplasm

MedGen UID:
148294
•Concept ID:
C0751366
•
Neoplastic Process
Synonyms: Cancer, Radiation Induced; Cancer, Radiation-Induced; Cancers, Radiation-Induced; Radiation Induced Cancer; Radiation-Induced Cancer; Radiation-Induced Cancers

Definition

A malignant neoplasm arising in a site exposed to radiation therapy. [from NCI]

Professional guidelines

PubMed

Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism: A Systematic Review and Meta-analysis.
Shim SR, Kitahara CM, Cha ES, Kim SJ, Bang YJ, Lee WJ
JAMA Netw Open 2021 Sep 1;4(9):e2125072. doi: 10.1001/jamanetworkopen.2021.25072. PMID: 34533571Free PMC Article
SEOM clinical guidelines for the treatment of head and neck cancer (2020).
Mesia R, Iglesias L, Lambea J, Martínez-Trufero J, Soria A, Taberna M, Trigo J, Chaves M, García-Castaño A, Cruz J
Clin Transl Oncol 2021 May;23(5):913-921. Epub 2021 Feb 26 doi: 10.1007/s12094-020-02533-1. PMID: 33635468Free PMC Article
Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update.
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, Danso MA, Dennis K, Dupuis LL, Dusetzina SB, Eng C, Feyer PC, Jordan K, Noonan K, Sparacio D, Somerfield MR, Lyman GH
J Clin Oncol 2017 Oct 1;35(28):3240-3261. Epub 2017 Jul 31 doi: 10.1200/JCO.2017.74.4789. PMID: 28759346

Recent clinical studies

Etiology

Preleukemic Fusion Genes Induced via Ionizing Radiation.
Kosik P, Skorvaga M, Belyaev I
Int J Mol Sci 2023 Apr 1;24(7) doi: 10.3390/ijms24076580. PMID: 37047553Free PMC Article
Are We Approaching the End of the Linear No-Threshold Era?
Doss M
J Nucl Med 2018 Dec;59(12):1786-1793. Epub 2018 Sep 27 doi: 10.2967/jnumed.118.217182. PMID: 30262515
Radiation-associated neoplasia: clinical, pathological and genomic correlates.
Sholl LM, Barletta JA, Hornick JL
Histopathology 2017 Jan;70(1):70-80. doi: 10.1111/his.13069. PMID: 27960236
Imaging modalities and radiation: benefit has its risks..
Shaw LJ, Achenbach S, Chandrashekhar Y, Dilsizian V, Hundley WG, Kern MJ, Kramer CM, Marwick TH, Zoghbi WA, Narula J
JACC Cardiovasc Imaging 2010 May;3(5):550-2. doi: 10.1016/j.jcmg.2010.04.001. PMID: 20466353
Radiation-induced sarcoma.
Patel SR
Curr Treat Options Oncol 2000 Aug;1(3):258-61. doi: 10.1007/s11864-000-0037-6. PMID: 12057168

Diagnosis

Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.
Abalo KD, Rage E, Leuraud K, Richardson DB, Le Pointe HD, Laurier D, Bernier MO
Pediatr Radiol 2021 Jan;51(1):45-56. Epub 2020 Sep 10 doi: 10.1007/s00247-020-04803-0. PMID: 32910229
Thyroid Cancer After Chernobyl: Re-Evaluation Needed.
Jargin S
Turk Patoloji Derg 2021;37(1):1-6. doi: 10.5146/tjpath.2020.01489. PMID: 32525210Free PMC Article
Radiation-associated peritoneal angiosarcoma.
Seo CJ, Lek SM, Tan GHC, Teo M
BMJ Case Rep 2017 May 22;2017 doi: 10.1136/bcr-2016-217887. PMID: 28536208Free PMC Article
Natural history of thyroid cancer [Review].
Takano T
Endocr J 2017 Mar 31;64(3):237-244. Epub 2017 Feb 2 doi: 10.1507/endocrj.EJ17-0026. PMID: 28154351
Radiation-induced sarcomas.
Mavrogenis AF, Angelini A, Pala E, Calabro T, Bianchi G, Casadei R, Ruggieri P
J Long Term Eff Med Implants 2011;21(3):233-40. doi: 10.1615/jlongtermeffmedimplants.v21.i3.70. PMID: 22150356

Therapy

Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.
Abalo KD, Rage E, Leuraud K, Richardson DB, Le Pointe HD, Laurier D, Bernier MO
Pediatr Radiol 2021 Jan;51(1):45-56. Epub 2020 Sep 10 doi: 10.1007/s00247-020-04803-0. PMID: 32910229
Epidemiology.
Glines WM
Health Phys 2020 Mar;118(3):249-253. doi: 10.1097/HP.0000000000001183. PMID: 31990769
Radiation-induced sarcomas.
Mavrogenis AF, Angelini A, Pala E, Calabro T, Bianchi G, Casadei R, Ruggieri P
J Long Term Eff Med Implants 2011;21(3):233-40. doi: 10.1615/jlongtermeffmedimplants.v21.i3.70. PMID: 22150356
Therapy-associated solid tumors.
Travis LB
Acta Oncol 2002;41(4):323-33. doi: 10.1080/028418602760169361. PMID: 12234023
Radiation-induced sarcoma.
Patel SR
Curr Treat Options Oncol 2000 Aug;1(3):258-61. doi: 10.1007/s11864-000-0037-6. PMID: 12057168

Prognosis

Thyroid Cancer After Chernobyl: Re-Evaluation Needed.
Jargin S
Turk Patoloji Derg 2021;37(1):1-6. doi: 10.5146/tjpath.2020.01489. PMID: 32525210Free PMC Article
Experience of thyroid gland status screening in postchernobyl period.
Drozd VM, Lushchyk ML, Danilova LI, Okulevich NM, Shimanskaya IG, Mitiukova TA, Shiglik N, Branovan I
Tsitol Genet 2016 Nov-Dec;50(6):8-14. PMID: 30484596
Radiation-induced sarcomas.
Mavrogenis AF, Angelini A, Pala E, Calabro T, Bianchi G, Casadei R, Ruggieri P
J Long Term Eff Med Implants 2011;21(3):233-40. doi: 10.1615/jlongtermeffmedimplants.v21.i3.70. PMID: 22150356
Radiation-induced sarcoma.
Patel SR
Curr Treat Options Oncol 2000 Aug;1(3):258-61. doi: 10.1007/s11864-000-0037-6. PMID: 12057168
Radiation-associated gliosarcoma.
Lach M, Wallace CJ, Krcek J, Curry B
Can Assoc Radiol J 1996 Jun;47(3):209-12. PMID: 8640419

Clinical prediction guides

Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.
Abalo KD, Rage E, Leuraud K, Richardson DB, Le Pointe HD, Laurier D, Bernier MO
Pediatr Radiol 2021 Jan;51(1):45-56. Epub 2020 Sep 10 doi: 10.1007/s00247-020-04803-0. PMID: 32910229
Overview of Biological, Epidemiological, and Clinical Evidence of Radiation Hormesis.
Shibamoto Y, Nakamura H
Int J Mol Sci 2018 Aug 13;19(8) doi: 10.3390/ijms19082387. PMID: 30104556Free PMC Article
Natural history of thyroid cancer [Review].
Takano T
Endocr J 2017 Mar 31;64(3):237-244. Epub 2017 Feb 2 doi: 10.1507/endocrj.EJ17-0026. PMID: 28154351
The use of computed tomography in pediatrics and the associated radiation exposure and estimated cancer risk.
Miglioretti DL, Johnson E, Williams A, Greenlee RT, Weinmann S, Solberg LI, Feigelson HS, Roblin D, Flynn MJ, Vanneman N, Smith-Bindman R
JAMA Pediatr 2013 Aug 1;167(8):700-7. doi: 10.1001/jamapediatrics.2013.311. PMID: 23754213Free PMC Article
Radiation-induced genomic instability.
Morgan WF
Health Phys 2011 Mar;100(3):280-1. doi: 10.1097/HP.0b013e3182082f12. PMID: 21556289Free PMC Article

Recent systematic reviews

Glutamine for prevention and alleviation of radiation-induced oral mucositis in patients with head and neck squamous cell cancer: Systematic review and meta-analysis of controlled trials.
Alsubaie HM, Alsini AY, Alsubaie KM, Abu-Zaid A, Alzahrani FR, Sayed S, Pathak AK, Alqahtani KH
Head Neck 2021 Oct;43(10):3199-3213. Epub 2021 Jul 9 doi: 10.1002/hed.26798. PMID: 34240498
Screening for Lung Cancer With Low-Dose Computed Tomography: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Jonas DE, Reuland DS, Reddy SM, Nagle M, Clark SD, Weber RP, Enyioha C, Malo TL, Brenner AT, Armstrong C, Coker-Schwimmer M, Middleton JC, Voisin C, Harris RP
JAMA 2021 Mar 9;325(10):971-987. doi: 10.1001/jama.2021.0377. PMID: 33687468
Interventions for mycosis fungoides.
Valipour A, Jäger M, Wu P, Schmitt J, Bunch C, Weberschock T
Cochrane Database Syst Rev 2020 Jul 7;7(7):CD008946. doi: 10.1002/14651858.CD008946.pub3. PMID: 32632956Free PMC Article
Prevention from radiation damage by natural products.
Fischer N, Seo EJ, Efferth T
Phytomedicine 2018 Aug 1;47:192-200. Epub 2017 Nov 13 doi: 10.1016/j.phymed.2017.11.005. PMID: 30166104
Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update.
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, Danso MA, Dennis K, Dupuis LL, Dusetzina SB, Eng C, Feyer PC, Jordan K, Noonan K, Sparacio D, Somerfield MR, Lyman GH
J Clin Oncol 2017 Oct 1;35(28):3240-3261. Epub 2017 Jul 31 doi: 10.1200/JCO.2017.74.4789. PMID: 28759346

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