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Brain infarction

MedGen UID:
148426
Concept ID:
C0751955
Disease or Syndrome
Synonyms: Brain Infarct; Brain Infarction; Brain Infarctions; Brain Infarcts; Infarct, Brain; Infarction, Brain; Infarctions, Brain; Infarcts, Brain
 
Monarch Initiative: MONDO:0005394

Definition

Tissue necrosis in any area of the brain, including the cerebral hemispheres, the cerebellum, and the brain stem. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by hypoxia and hypoglycemia in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. [from MONDO]

Professional guidelines

PubMed

Thimukonda Jegadeesan J, Baldia M, Basu B
Acta Biomater 2022 Dec;154:63-82. Epub 2022 Oct 19 doi: 10.1016/j.actbio.2022.10.030. PMID: 36272686
Wu JW, Yang CP; Treatment Guideline Subcommittee of the Taiwan Headache Society
Acta Neurol Taiwan 2022 Sep 30;31(3):164-202. PMID: 36089629
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Recent clinical studies

Etiology

Abdelrasoul AA, Elsebaie NA, Gamaleldin OA, Khalifa MH, Razek AAKA
J Comput Assist Tomogr 2019 May/Jun;43(3):443-451. doi: 10.1097/RCT.0000000000000865. PMID: 31082950
Gonçalves B, Turon R, Mendes A, Melo N, Lacerda P, Brasil P, Bozza FA, Kurtz P, Righy C
World Neurosurg 2018 Jul;115:e292-e298. Epub 2018 Apr 13 doi: 10.1016/j.wneu.2018.04.037. PMID: 29660554
Moroni F, Ammirati E, Magnoni M, D'Ascenzo F, Anselmino M, Anzalone N, Rocca MA, Falini A, Filippi M, Camici PG
Int J Cardiol 2016 Nov 15;223:681-687. Epub 2016 Aug 13 doi: 10.1016/j.ijcard.2016.08.234. PMID: 27568989
Gupta A, Giambrone AE, Gialdini G, Finn C, Delgado D, Gutierrez J, Wright C, Beiser AS, Seshadri S, Pandya A, Kamel H
Stroke 2016 Mar;47(3):719-25. doi: 10.1161/STROKEAHA.115.011889. PMID: 26888534Free PMC Article
Dlamini N, Billinghurst L, Kirkham FJ
Neurosurg Clin N Am 2010 Jul;21(3):511-27. doi: 10.1016/j.nec.2010.03.006. PMID: 20561500Free PMC Article

Diagnosis

Kichloo A, Jamal SM, Zain EA, Wani F, Vipparala N
J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619867355. doi: 10.1177/2324709619867355. PMID: 31394937Free PMC Article
Welgampola MS, Young AS, Pogson JM, Bradshaw AP, Halmagyi GM
Pract Neurol 2019 Dec;19(6):492-501. Epub 2019 Jul 20 doi: 10.1136/practneurol-2019-002199. PMID: 31326945
Gonçalves B, Turon R, Mendes A, Melo N, Lacerda P, Brasil P, Bozza FA, Kurtz P, Righy C
World Neurosurg 2018 Jul;115:e292-e298. Epub 2018 Apr 13 doi: 10.1016/j.wneu.2018.04.037. PMID: 29660554
Gupta A, Giambrone AE, Gialdini G, Finn C, Delgado D, Gutierrez J, Wright C, Beiser AS, Seshadri S, Pandya A, Kamel H
Stroke 2016 Mar;47(3):719-25. doi: 10.1161/STROKEAHA.115.011889. PMID: 26888534Free PMC Article
Dlamini N, Billinghurst L, Kirkham FJ
Neurosurg Clin N Am 2010 Jul;21(3):511-27. doi: 10.1016/j.nec.2010.03.006. PMID: 20561500Free PMC Article

Therapy

Kühne M, Krisai P, Coslovsky M, Rodondi N, Müller A, Beer JH, Ammann P, Auricchio A, Moschovitis G, Hayoz D, Kobza R, Shah D, Stephan FP, Schläpfer J, Di Valentino M, Aeschbacher S, Ehret G, Eken C, Monsch A, Roten L, Schwenkglenks M, Springer A, Sticherling C, Reichlin T, Zuern CS, Meyre PB, Blum S, Sinnecker T, Würfel J, Bonati LH, Conen D, Osswald S; Swiss-AF Investigators
Eur Heart J 2022 Jun 6;43(22):2127-2135. doi: 10.1093/eurheartj/ehac020. PMID: 35171989Free PMC Article
Søndergaard L, Kasner SE, Rhodes JF, Andersen G, Iversen HK, Nielsen-Kudsk JE, Settergren M, Sjöstrand C, Roine RO, Hildick-Smith D, Spence JD, Thomassen L; Gore REDUCE Clinical Study Investigators
N Engl J Med 2017 Sep 14;377(11):1033-1042. doi: 10.1056/NEJMoa1707404. PMID: 28902580
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL
J Am Coll Cardiol 2013 Jan 29;61(4):404-410. Epub 2012 Dec 19 doi: 10.1016/j.jacc.2012.10.027. PMID: 23265346
Dlamini N, Billinghurst L, Kirkham FJ
Neurosurg Clin N Am 2010 Jul;21(3):511-27. doi: 10.1016/j.nec.2010.03.006. PMID: 20561500Free PMC Article
Chabriat H, Joutel A, Dichgans M, Tournier-Lasserve E, Bousser MG
Lancet Neurol 2009 Jul;8(7):643-53. doi: 10.1016/S1474-4422(09)70127-9. PMID: 19539236

Prognosis

Schattner A
Am J Med 2022 Jan;135(1):12-14. Epub 2021 Sep 8 doi: 10.1016/j.amjmed.2021.07.044. PMID: 34508701
Guo J, Zhou C, Yue L, Yan F, Shi J
Neurocrit Care 2021 Apr;34(2):657-668. doi: 10.1007/s12028-020-01048-5. PMID: 32648193
Gonçalves B, Turon R, Mendes A, Melo N, Lacerda P, Brasil P, Bozza FA, Kurtz P, Righy C
World Neurosurg 2018 Jul;115:e292-e298. Epub 2018 Apr 13 doi: 10.1016/j.wneu.2018.04.037. PMID: 29660554
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL
J Am Coll Cardiol 2013 Jan 29;61(4):404-410. Epub 2012 Dec 19 doi: 10.1016/j.jacc.2012.10.027. PMID: 23265346
Lastilla M
Clin Exp Hypertens 2006 Apr-May;28(3-4):205-15. doi: 10.1080/10641960600549082. PMID: 16833026

Clinical prediction guides

Chang K, Huang CH, Chen TC, Lin CY, Lu PL, Chen YH
J Microbiol Immunol Infect 2021 Oct;54(5):885-892. Epub 2021 Mar 31 doi: 10.1016/j.jmii.2021.03.009. PMID: 33840603
Wang Q, Liu Y, Han L, He F, Cai N, Zhang Q, Wang J
Am J Emerg Med 2021 Mar;41:55-59. Epub 2020 Dec 23 doi: 10.1016/j.ajem.2020.12.036. PMID: 33387929
Hahne K, Mönnig G, Samol A
Vasc Health Risk Manag 2016;12:65-74. Epub 2016 Mar 7 doi: 10.2147/VHRM.S81807. PMID: 27022272Free PMC Article
Kovács KR, Czuriga D, Bereczki D, Bornstein NM, Csiba L
Int J Stroke 2013 Jul;8(5):334-47. Epub 2012 Aug 1 doi: 10.1111/j.1747-4949.2012.00851.x. PMID: 22863197
Wardlaw JM, Mielke O
Radiology 2005 May;235(2):444-53. doi: 10.1148/radiol.2352040262. PMID: 15858087

Recent systematic reviews

Ng FC, Yassi N, Sharma G, Brown SB, Goyal M, Majoie CBLM, Jovin TG, Hill MD, Muir KW, Saver JL, Guillemin F, Demchuk AM, Menon BK, San Roman L, Liebeskind DS, White P, Dippel DWJ, Davalos A, Bracard S, Mitchell PJ, Wald MJ, Davis SM, Sheth KN, Kimberly WT, Campbell BCV; HERMES Collaborators
Stroke 2021 Nov;52(11):3450-3458. Epub 2021 Aug 13 doi: 10.1161/STROKEAHA.120.033246. PMID: 34384229Free PMC Article
Debette S, Schilling S, Duperron MG, Larsson SC, Markus HS
JAMA Neurol 2019 Jan 1;76(1):81-94. doi: 10.1001/jamaneurol.2018.3122. PMID: 30422209Free PMC Article
Gonçalves B, Turon R, Mendes A, Melo N, Lacerda P, Brasil P, Bozza FA, Kurtz P, Righy C
World Neurosurg 2018 Jul;115:e292-e298. Epub 2018 Apr 13 doi: 10.1016/j.wneu.2018.04.037. PMID: 29660554
Gupta A, Giambrone AE, Gialdini G, Finn C, Delgado D, Gutierrez J, Wright C, Beiser AS, Seshadri S, Pandya A, Kamel H
Stroke 2016 Mar;47(3):719-25. doi: 10.1161/STROKEAHA.115.011889. PMID: 26888534Free PMC Article
Prabhakaran S, Ruff I, Bernstein RA
JAMA 2015 Apr 14;313(14):1451-62. doi: 10.1001/jama.2015.3058. PMID: 25871671

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