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Infectious mediastinitis

MedGen UID:
149095
•Concept ID:
C0729554
•
Disease or Syndrome
Synonym: Infectious Mediastinitis
SNOMED CT: Infectious mediastinitis (312157006)

Definition

An acute or chronic infectious process affecting the mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfectious mediastinitis

Professional guidelines

PubMed

Deep Sternal Wound Infection: Diagnosis, Treatment and Prevention.
Phoon PHY, Hwang NC
J Cardiothorac Vasc Anesth 2020 Jun;34(6):1602-1613. Epub 2019 Sep 18 doi: 10.1053/j.jvca.2019.09.019. PMID: 31623967
Fetal primary pleural effusions: Prenatal diagnosis and management.
Abbasi N, Ryan G
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:66-77. Epub 2019 Jan 12 doi: 10.1016/j.bpobgyn.2019.01.005. PMID: 30737016
Histoplasmosis: Up-to-Date Evidence-Based Approach to Diagnosis and Management.
Hage CA, Azar MM, Bahr N, Loyd J, Wheat LJ
Semin Respir Crit Care Med 2015 Oct;36(5):729-45. Epub 2015 Sep 23 doi: 10.1055/s-0035-1562899. PMID: 26398539

Recent clinical studies

Etiology

Non-infectious sternal dehiscence after coronary artery bypass surgery.
Silverborn M, Heitmann LA, Sveinsdottir N, Rögnvaldsson S, Kristjansson TT, Gudbjartsson T
J Cardiothorac Surg 2022 Oct 3;17(1):249. doi: 10.1186/s13019-022-02015-1. PMID: 36192764Free PMC Article
Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery.
Foldyna B, Mueller M, Etz CD, Luecke C, Haunschild J, Hoffmann I, Gutberlet M, Lehmkuhl L
Eur Radiol 2019 Jun;29(6):2949-2957. Epub 2019 Jan 10 doi: 10.1007/s00330-018-5946-5. PMID: 30631921
Infectious mediastinitis after cardiovascular surgery: role of computed tomography.
Yamashiro T, Kamiya H, Murayama S, Unten S, Nakayama T, Gibo M, Kuniyoshi Y
Radiat Med 2008 Jul;26(6):343-7. Epub 2008 Aug 3 doi: 10.1007/s11604-008-0238-7. PMID: 18677608
Infectious mediastinitis after cardiac operations: computed tomographic findings.
Misawa Y, Fuse K, Hasegawa T
Ann Thorac Surg 1998 Mar;65(3):622-4. doi: 10.1016/s0003-4975(97)01339-8. PMID: 9527183

Diagnosis

Non-infectious sternal dehiscence after coronary artery bypass surgery.
Silverborn M, Heitmann LA, Sveinsdottir N, Rögnvaldsson S, Kristjansson TT, Gudbjartsson T
J Cardiothorac Surg 2022 Oct 3;17(1):249. doi: 10.1186/s13019-022-02015-1. PMID: 36192764Free PMC Article
Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery.
Foldyna B, Mueller M, Etz CD, Luecke C, Haunschild J, Hoffmann I, Gutberlet M, Lehmkuhl L
Eur Radiol 2019 Jun;29(6):2949-2957. Epub 2019 Jan 10 doi: 10.1007/s00330-018-5946-5. PMID: 30631921
Infectious mediastinitis after cardiovascular surgery: role of computed tomography.
Yamashiro T, Kamiya H, Murayama S, Unten S, Nakayama T, Gibo M, Kuniyoshi Y
Radiat Med 2008 Jul;26(6):343-7. Epub 2008 Aug 3 doi: 10.1007/s11604-008-0238-7. PMID: 18677608
A case of multifocal fibrosclerosis with intracardiac solid masses.
Takikita-Suzuki M, Takeuchi E, Nakashima Y, Yamamoto T, Mukai K, Ogasawara K
Hum Pathol 2006 Apr;37(4):493-7. Epub 2006 Feb 7 doi: 10.1016/j.humpath.2005.11.017. PMID: 16564927
Infectious mediastinitis after cardiac operations: computed tomographic findings.
Misawa Y, Fuse K, Hasegawa T
Ann Thorac Surg 1998 Mar;65(3):622-4. doi: 10.1016/s0003-4975(97)01339-8. PMID: 9527183

Therapy

Non-infectious sternal dehiscence after coronary artery bypass surgery.
Silverborn M, Heitmann LA, Sveinsdottir N, Rögnvaldsson S, Kristjansson TT, Gudbjartsson T
J Cardiothorac Surg 2022 Oct 3;17(1):249. doi: 10.1186/s13019-022-02015-1. PMID: 36192764Free PMC Article
Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery.
Foldyna B, Mueller M, Etz CD, Luecke C, Haunschild J, Hoffmann I, Gutberlet M, Lehmkuhl L
Eur Radiol 2019 Jun;29(6):2949-2957. Epub 2019 Jan 10 doi: 10.1007/s00330-018-5946-5. PMID: 30631921
EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis.
Aerts JG, Kloover J, Los J, van der Heijden O, Janssens A, Tournoy KG
J Thorac Oncol 2008 Oct;3(10):1191-3. doi: 10.1097/JTO.0b013e3181872752. PMID: 18827619
Mycotic pseudo-aneurysm of the ascending thoracic aorta after cardiac transplantation.
Palanichamy N, Gregoric ID, La Francesca S, Smart FW
J Heart Lung Transplant 2006 Jun;25(6):730-3. Epub 2006 May 2 doi: 10.1016/j.healun.2006.02.009. PMID: 16730580

Prognosis

Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery.
Foldyna B, Mueller M, Etz CD, Luecke C, Haunschild J, Hoffmann I, Gutberlet M, Lehmkuhl L
Eur Radiol 2019 Jun;29(6):2949-2957. Epub 2019 Jan 10 doi: 10.1007/s00330-018-5946-5. PMID: 30631921
A case of multifocal fibrosclerosis with intracardiac solid masses.
Takikita-Suzuki M, Takeuchi E, Nakashima Y, Yamamoto T, Mukai K, Ogasawara K
Hum Pathol 2006 Apr;37(4):493-7. Epub 2006 Feb 7 doi: 10.1016/j.humpath.2005.11.017. PMID: 16564927
Mediastinitis secondary to an odontogenic infection. A case report.
Izadi K, Lazow SK, Berger JR
N Y State Dent J 2003 Dec;69(10):28-30. PMID: 14974190
Infectious mediastinitis after cardiac operations: computed tomographic findings.
Misawa Y, Fuse K, Hasegawa T
Ann Thorac Surg 1998 Mar;65(3):622-4. doi: 10.1016/s0003-4975(97)01339-8. PMID: 9527183

Clinical prediction guides

Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery.
Foldyna B, Mueller M, Etz CD, Luecke C, Haunschild J, Hoffmann I, Gutberlet M, Lehmkuhl L
Eur Radiol 2019 Jun;29(6):2949-2957. Epub 2019 Jan 10 doi: 10.1007/s00330-018-5946-5. PMID: 30631921
Infectious mediastinitis after cardiovascular surgery: role of computed tomography.
Yamashiro T, Kamiya H, Murayama S, Unten S, Nakayama T, Gibo M, Kuniyoshi Y
Radiat Med 2008 Jul;26(6):343-7. Epub 2008 Aug 3 doi: 10.1007/s11604-008-0238-7. PMID: 18677608
A case of multifocal fibrosclerosis with intracardiac solid masses.
Takikita-Suzuki M, Takeuchi E, Nakashima Y, Yamamoto T, Mukai K, Ogasawara K
Hum Pathol 2006 Apr;37(4):493-7. Epub 2006 Feb 7 doi: 10.1016/j.humpath.2005.11.017. PMID: 16564927
Infectious mediastinitis after cardiac operations: computed tomographic findings.
Misawa Y, Fuse K, Hasegawa T
Ann Thorac Surg 1998 Mar;65(3):622-4. doi: 10.1016/s0003-4975(97)01339-8. PMID: 9527183

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