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Chronic atrial fibrillation

MedGen UID:
151957
Concept ID:
C0694539
Disease or Syndrome
Synonyms: Chronic AF; Chronic AFib; Chronic Atrial Fibrillation
SNOMED CT: Chronic atrial fibrillation (426749004)

Definition

A disorder characterized by a long standing and persistent uncoordinated atrial myocardium activation due to multiple reentry circuits with consequent deterioration of atrial mechanical function. Instead of intermittently contracting, the atria quiver continuously in a chaotic pattern, causing a totally irregular, often tachycardia ventricular rate. On the ECG it is characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape, and timing, associated with an irregular, frequently rapid ventricular response when atrioventricular conduction is intact. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic atrial fibrillation

Professional guidelines

PubMed

Handelsman Y, Butler J, Bakris GL, DeFronzo RA, Fonarow GC, Green JB, Grunberger G, Januzzi JL Jr, Klein S, Kushner PR, McGuire DK, Michos ED, Morales J, Pratley RE, Weir MR, Wright E, Fonseca VA
J Diabetes Complications 2023 Feb;37(2):108389. Epub 2023 Jan 3 doi: 10.1016/j.jdiacomp.2022.108389. PMID: 36669322
Nimmo C, Wright M, Goldsmith D
Am Heart J 2013 Aug;166(2):230-9. Epub 2013 Jun 15 doi: 10.1016/j.ahj.2013.05.010. PMID: 23895805
Nikolaidou T, Channer KS
Postgrad Med J 2009 Jun;85(1004):303-12. doi: 10.1136/pgmj.2008.068908. PMID: 19528305

Recent clinical studies

Etiology

Philip I, Berroëta C, Leblanc I
Curr Opin Anaesthesiol 2014 Jun;27(3):344-52. doi: 10.1097/ACO.0000000000000070. PMID: 24633361
Nair M, George LK, Koshy SK
J Am Board Fam Med 2011 Jan-Feb;24(1):86-92. doi: 10.3122/jabfm.2011.01.080096. PMID: 21209348
Hardin SR, Steele JR
J Gerontol Nurs 2008 Jul;34(7):26-33; quiz 34-5. doi: 10.3928/00989134-20080701-04. PMID: 18649821
Brignole M
Clin Geriatr Med 2002 May;18(2):211-27. doi: 10.1016/s0749-0690(02)00006-x. PMID: 12180244
Langguth DM, Klestov A, Denaro C
Intern Med J 2002 Aug;32(8):419-20. doi: 10.1046/j.1445-5994.2002.00260.x. PMID: 12162400

Diagnosis

Zoghbi WA, Levine RA, Flachskampf F, Grayburn P, Gillam L, Leipsic J, Thomas JD, Kwong RY, Vandervoort P, Chandrashekhar Y
JACC Cardiovasc Imaging 2022 Nov;15(11):1870-1882. doi: 10.1016/j.jcmg.2022.08.016. PMID: 36357130
Jang SJ, Wong SC, Mosadegh B
Cardiology 2021;146(3):384-391. Epub 2021 Mar 18 doi: 10.1159/000513901. PMID: 33735867
Tuomainen PO, Magga J, Fedacko J, Kärkkäinen S, Miettinen K, Vanninen E, Kuusisto J, Peuhkurinen KJ
Clin Physiol Funct Imaging 2014 Mar;34(2):133-7. Epub 2013 Jul 24 doi: 10.1111/cpf.12075. PMID: 23879372
Hardin SR, Steele JR
J Gerontol Nurs 2008 Jul;34(7):26-33; quiz 34-5. doi: 10.3928/00989134-20080701-04. PMID: 18649821
Brignole M
Clin Geriatr Med 2002 May;18(2):211-27. doi: 10.1016/s0749-0690(02)00006-x. PMID: 12180244

Therapy

Ferrari F, Santander IRMF, Stein R
Curr Cardiol Rev 2020;16(2):141-146. doi: 10.2174/1573403X15666190618110941. PMID: 31237216Free PMC Article
Philip I, Berroëta C, Leblanc I
Curr Opin Anaesthesiol 2014 Jun;27(3):344-52. doi: 10.1097/ACO.0000000000000070. PMID: 24633361
Nair M, George LK, Koshy SK
J Am Board Fam Med 2011 Jan-Feb;24(1):86-92. doi: 10.3122/jabfm.2011.01.080096. PMID: 21209348
Brignole M
Clin Geriatr Med 2002 May;18(2):211-27. doi: 10.1016/s0749-0690(02)00006-x. PMID: 12180244
Langguth DM, Klestov A, Denaro C
Intern Med J 2002 Aug;32(8):419-20. doi: 10.1046/j.1445-5994.2002.00260.x. PMID: 12162400

Prognosis

Zoghbi WA, Levine RA, Flachskampf F, Grayburn P, Gillam L, Leipsic J, Thomas JD, Kwong RY, Vandervoort P, Chandrashekhar Y
JACC Cardiovasc Imaging 2022 Nov;15(11):1870-1882. doi: 10.1016/j.jcmg.2022.08.016. PMID: 36357130
Kashiwagi M, Ojima T, Hayata K, Kitadani J, Takeuchi A, Kuroi A, Terada K, Tanimoto T, Tanaka A, Yamaue H
J Gastrointest Surg 2022 Dec;26(12):2451-2459. Epub 2022 Oct 21 doi: 10.1007/s11605-022-05493-9. PMID: 36271198
Jang SJ, Wong SC, Mosadegh B
Cardiology 2021;146(3):384-391. Epub 2021 Mar 18 doi: 10.1159/000513901. PMID: 33735867
Philip I, Berroëta C, Leblanc I
Curr Opin Anaesthesiol 2014 Jun;27(3):344-52. doi: 10.1097/ACO.0000000000000070. PMID: 24633361
Langguth DM, Klestov A, Denaro C
Intern Med J 2002 Aug;32(8):419-20. doi: 10.1046/j.1445-5994.2002.00260.x. PMID: 12162400

Clinical prediction guides

Zoghbi WA, Levine RA, Flachskampf F, Grayburn P, Gillam L, Leipsic J, Thomas JD, Kwong RY, Vandervoort P, Chandrashekhar Y
JACC Cardiovasc Imaging 2022 Nov;15(11):1870-1882. doi: 10.1016/j.jcmg.2022.08.016. PMID: 36357130
Kashiwagi M, Ojima T, Hayata K, Kitadani J, Takeuchi A, Kuroi A, Terada K, Tanimoto T, Tanaka A, Yamaue H
J Gastrointest Surg 2022 Dec;26(12):2451-2459. Epub 2022 Oct 21 doi: 10.1007/s11605-022-05493-9. PMID: 36271198
Jang SJ, Wong SC, Mosadegh B
Cardiology 2021;146(3):384-391. Epub 2021 Mar 18 doi: 10.1159/000513901. PMID: 33735867
Philip I, Berroëta C, Leblanc I
Curr Opin Anaesthesiol 2014 Jun;27(3):344-52. doi: 10.1097/ACO.0000000000000070. PMID: 24633361
Brignole M
Clin Geriatr Med 2002 May;18(2):211-27. doi: 10.1016/s0749-0690(02)00006-x. PMID: 12180244

Recent systematic reviews

Yang J, Zhang X, Wang XY, Zhang C, Chen SZ, Hu SJ
BMC Cardiovasc Disord 2019 Nov 26;19(1):261. doi: 10.1186/s12872-019-1209-x. PMID: 31771529Free PMC Article
Slotwiner DJ, Raitt MH, Del-Carpio Munoz F, Mulpuru SK, Nasser N, Peterson PN
Circulation 2019 Aug 20;140(8):e483-e503. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000629. PMID: 30586773
Slotwiner DJ, Raitt MH, Del-Carpio Munoz F, Mulpuru SK, Nasser N, Peterson PN
Heart Rhythm 2019 Sep;16(9):e280-e298. Epub 2018 Nov 6 doi: 10.1016/j.hrthm.2018.10.035. PMID: 30412776
Slotwiner DJ, Raitt MH, Del-Carpio Munoz F, Mulpuru SK, Nasser N, Peterson PN
J Am Coll Cardiol 2019 Aug 20;74(7):988-1008. Epub 2018 Nov 6 doi: 10.1016/j.jacc.2018.10.045. PMID: 30412708
Nikolaidou T, Channer KS
Postgrad Med J 2009 Jun;85(1004):303-12. doi: 10.1136/pgmj.2008.068908. PMID: 19528305

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