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Ancylostomiasis

MedGen UID:
1522
Concept ID:
C0002831
Disease or Syndrome
Synonyms: Ancylostoma duodenale infection; Hookworm infection
SNOMED CT: Ancylostomiasis (63479002)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005645
Orphanet: ORPHA78

Definition

A hookworm infection caused primarily by the species <i>Ancylostoma duodenale </i> or <i>Necator americanus</i>, usually acquired through penetration of the skin, (often asymptomatic but that can also manifest with an allergic reaction at the site of skin penetration), followed by the migration of larva through the bloodstream to the lungs (causing asymptomatic pneumonitis, eosinophilia) and finally reaching and colonizing the small intestines where they cause blood extravasation leading to diarrhea, abdominal pain, and when untreated, melena, iron-deficiency anemia and protein malnutrition. [from ORDO]

Professional guidelines

PubMed

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Recent clinical studies

Etiology

Iqbal M, Khan W, Khan MF, Khan I
J Pak Med Assoc 2021 Aug;71(8):2058-2060. doi: 10.47391/JPMA.1055. PMID: 34418029
O'Connell EM, Mitchell T, Papaiakovou M, Pilotte N, Lee D, Weinberg M, Sakulrak P, Tongsukh D, Oduro-Boateng G, Harrison S, Williams SA, Stauffer WM, Nutman TB
Emerg Infect Dis 2018 Aug;24(8):1472-81. doi: 10.3201/eid2408.180280. PMID: 30014834Free PMC Article
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Emerg Infect Dis 2017 Feb;23(2):252-257. doi: 10.3201/eid2302.160822. PMID: 28098526Free PMC Article
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Diagnosis

Sears WJ, Cardenas J, Kubofcik J, Nutman TB, Cooper PJ
Emerg Infect Dis 2022 Sep;28(9):1867-1869. doi: 10.3201/eid2809.220248. PMID: 35997627Free PMC Article
Colella V, Bradbury R, Traub R
Trends Parasitol 2021 Sep;37(9):844-845. Epub 2021 May 25 doi: 10.1016/j.pt.2021.04.013. PMID: 34049804
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Rivera-Roig V, Sánchez JL, Hillyer GV
Int J Dermatol 2008 Mar;47(3):246-8. doi: 10.1111/j.1365-4632.2008.03469.x. PMID: 18289324

Therapy

Nezami R, Blanchard J, Godoy P
Can Vet J 2023 Apr;64(4):372-378. PMID: 37008647Free PMC Article
Iqbal M, Khan W, Khan MF, Khan I
J Pak Med Assoc 2021 Aug;71(8):2058-2060. doi: 10.47391/JPMA.1055. PMID: 34418029
Bhatia V, Das MK, Kumar P, Arora NK
Indian Pediatr 2010 Feb;47(2):190-2. doi: 10.1007/s13312-010-0033-2. PMID: 20228435
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Botero D
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Prognosis

AbdAllah M
Gastroenterol Nurs 2019 Mar/Apr;42(2):179-180. doi: 10.1097/SGA.0000000000000423. PMID: 30946305
Deesomsak M, Sawanyawisuth K, Prachayakul V
Trop Biomed 2014 Mar;31(1):187-9. PMID: 24862060
Zhang BL, Jiang LL, Chen CX, Zhong BS, Li YM
J Gastroenterol Hepatol 2010 Jan;25(1):75-9. Epub 2009 Oct 9 doi: 10.1111/j.1440-1746.2009.06016.x. PMID: 19817955
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Clinical prediction guides

Schwarz EM, Hu Y, Antoshechkin I, Miller MM, Sternberg PW, Aroian RV
Nat Genet 2015 Apr;47(4):416-22. Epub 2015 Mar 2 doi: 10.1038/ng.3237. PMID: 25730766Free PMC Article
De Mello IN, Braga FR, Monteiro TS, Freitas LG, Araujo JM, Soares FE, Araújo JV
Rev Iberoam Micol 2014 Apr-Jun;31(2):114-8. Epub 2013 May 29 doi: 10.1016/j.riam.2013.05.003. PMID: 23727473
Prociv P, Croese J
Acta Trop 1996 Sep;62(1):23-44. doi: 10.1016/s0001-706x(96)00016-2. PMID: 8971276
Hotez PJ, Hawdon JM, Cappello M, Jones BF, Ghosh K, Volvovitz F, Xiao SH
Pediatr Res 1996 Oct;40(4):515-21. doi: 10.1203/00006450-199610000-00001. PMID: 8888276
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Recent systematic reviews

Stracke K, Jex AR, Traub RJ
Am J Trop Med Hyg 2020 Jul;103(1):64-68. Epub 2020 Apr 23 doi: 10.4269/ajtmh.20-0060. PMID: 32342850Free PMC Article
Hassan-Kadle MA, Osman MS, Ogurtsov PP
World J Gastroenterol 2018 Sep 14;24(34):3927-3957. doi: 10.3748/wjg.v24.i34.3927. PMID: 30228786Free PMC Article

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