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Ancylostomiasis

MedGen UID:
1522
Concept ID:
C0002831
Disease or Syndrome
Synonyms: Ancylostoma duodenale infection; Hookworm infection
SNOMED CT: Ancylostomiasis (63479002)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005645
Orphanet: ORPHA78

Definition

A hookworm infection caused primarily by the species <i>Ancylostoma duodenale </i> or <i>Necator americanus</i>, usually acquired through penetration of the skin, (often asymptomatic but that can also manifest with an allergic reaction at the site of skin penetration), followed by the migration of larva through the bloodstream to the lungs (causing asymptomatic pneumonitis, eosinophilia) and finally reaching and colonizing the small intestines where they cause blood extravasation leading to diarrhea, abdominal pain, and when untreated, melena, iron-deficiency anemia and protein malnutrition. [from ORDO]

Professional guidelines

PubMed

Iqbal M, Khan W, Khan MF, Khan I
J Pak Med Assoc 2021 Aug;71(8):2058-2060. doi: 10.47391/JPMA.1055. PMID: 34418029
Prasad R, Mathur PP, Taneja VK, Jagota SC
Clin Ther 1985;7(2):164-8. PMID: 3986860
Zaidi ZH
Indian Pediatr 1972 Oct;9(10):638-40. PMID: 4657786

Recent clinical studies

Etiology

Shlash SA, Alzubaidi ZF, Saleh HA
J Med Life 2022 Apr;15(4):479-482. doi: 10.25122/jml-2021-0383. PMID: 35646178Free PMC Article
da Silva VJ, Dias SRC, Alves WP, Furtado LFV, Serafim LR, Moreira TB, de Aguiar PHN, de Faria AMC, Rabelo ÉML
Mol Biochem Parasitol 2019 Sep;232:111200. Epub 2019 Jul 12 doi: 10.1016/j.molbiopara.2019.111200. PMID: 31306675
Hu Z, Chen H, Huang L, Chen S, Huang Z, Qin S, Zhong J, Qin X, Li S
J Clin Lab Anal 2019 Mar;33(3):e22705. Epub 2018 Nov 2 doi: 10.1002/jcla.22705. PMID: 30390342Free PMC Article
Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM
Hum Vaccin 2011 Nov;7(11):1234-44. Epub 2011 Nov 1 doi: 10.4161/hv.7.11.18443. PMID: 22064562Free PMC Article
Ansaloni L
World J Surg 1996 Jun;20(5):613-7. doi: 10.1007/s002689900094. PMID: 8661639

Diagnosis

Sears WJ, Cardenas J, Kubofcik J, Nutman TB, Cooper PJ
Emerg Infect Dis 2022 Sep;28(9):1867-1869. doi: 10.3201/eid2809.220248. PMID: 35997627Free PMC Article
Xu FF, Niu YF, Chen WQ, Liu SS, Li JR, Jiang P, Wang ZQ, Cui J, Zhang X
Parasit Vectors 2021 Oct 14;14(1):537. doi: 10.1186/s13071-021-05035-3. PMID: 34649597Free PMC Article
Colella V, Bradbury R, Traub R
Trends Parasitol 2021 Sep;37(9):844-845. Epub 2021 May 25 doi: 10.1016/j.pt.2021.04.013. PMID: 34049804
Hu Z, Chen H, Huang L, Chen S, Huang Z, Qin S, Zhong J, Qin X, Li S
J Clin Lab Anal 2019 Mar;33(3):e22705. Epub 2018 Nov 2 doi: 10.1002/jcla.22705. PMID: 30390342Free PMC Article
Sarinas PS, Chitkara RK
Semin Respir Infect 1997 Jun;12(2):130-7. PMID: 9195678

Therapy

Nezami R, Blanchard J, Godoy P
Can Vet J 2023 Apr;64(4):372-378. PMID: 37008647Free PMC Article
Shlash SA, Alzubaidi ZF, Saleh HA
J Med Life 2022 Apr;15(4):479-482. doi: 10.25122/jml-2021-0383. PMID: 35646178Free PMC Article
Georgiev VS
Expert Opin Investig Drugs 2000 May;9(5):1065-78. doi: 10.1517/13543784.9.5.1065. PMID: 11060728
Sarinas PS, Chitkara RK
Semin Respir Infect 1997 Jun;12(2):130-7. PMID: 9195678
Hotez PJ, Pritchard DI
Sci Am 1995 Jun;272(6):68-74. doi: 10.1038/scientificamerican0695-68. PMID: 7761817

Prognosis

AbdAllah M
Gastroenterol Nurs 2019 Mar/Apr;42(2):179-180. doi: 10.1097/SGA.0000000000000423. PMID: 30946305
Hu Y, Miller M, Zhang B, Nguyen TT, Nielsen MK, Aroian RV
PLoS Negl Trop Dis 2018 May;12(5):e0006506. Epub 2018 May 18 doi: 10.1371/journal.pntd.0006506. PMID: 29775454Free PMC Article
Casmo V, Augusto G, Nala R, Sabonete A, Carvalho-Costa FA
Rev Inst Med Trop Sao Paulo 2014 May-Jun;56(3):219-24. doi: 10.1590/s0036-46652014000300007. PMID: 24879000Free PMC Article
Deesomsak M, Sawanyawisuth K, Prachayakul V
Trop Biomed 2014 Mar;31(1):187-9. PMID: 24862060
Rabelo EM, Hall RS, Loukas A, Cooper L, Hu M, Ranganathan S, Gasser RB
Biotechnol Adv 2009 Mar-Apr;27(2):122-32. Epub 2008 Oct 18 doi: 10.1016/j.biotechadv.2008.10.002. PMID: 18977428

Clinical prediction guides

Anderson AS, Trumble BC, Hové C, Kraft TS, Kaplan H, Gurven M, Blackwell AD
Am J Hum Biol 2020 Mar;32(2):e23337. Epub 2019 Oct 23 doi: 10.1002/ajhb.23337. PMID: 31642576Free PMC Article
da Silva VJ, Dias SRC, Alves WP, Furtado LFV, Serafim LR, Moreira TB, de Aguiar PHN, de Faria AMC, Rabelo ÉML
Mol Biochem Parasitol 2019 Sep;232:111200. Epub 2019 Jul 12 doi: 10.1016/j.molbiopara.2019.111200. PMID: 31306675
Rabelo EM, Hall RS, Loukas A, Cooper L, Hu M, Ranganathan S, Gasser RB
Biotechnol Adv 2009 Mar-Apr;27(2):122-32. Epub 2008 Oct 18 doi: 10.1016/j.biotechadv.2008.10.002. PMID: 18977428
Prociv P, Croese J
Acta Trop 1996 Sep;62(1):23-44. doi: 10.1016/s0001-706x(96)00016-2. PMID: 8971276
Pene P, Mojon M, Garin JP, Coulaud JP, Rossignol JF
Am J Trop Med Hyg 1982 Mar;31(2):263-6. doi: 10.4269/ajtmh.1982.31.263. PMID: 7041665

Recent systematic reviews

Stracke K, Jex AR, Traub RJ
Am J Trop Med Hyg 2020 Jul;103(1):64-68. Epub 2020 Apr 23 doi: 10.4269/ajtmh.20-0060. PMID: 32342850Free PMC Article
Hassan-Kadle MA, Osman MS, Ogurtsov PP
World J Gastroenterol 2018 Sep 14;24(34):3927-3957. doi: 10.3748/wjg.v24.i34.3927. PMID: 30228786Free PMC Article

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