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Polar Spongioblastoma

MedGen UID:
154309
•Concept ID:
C0555199
•
Neoplastic Process
Synonyms: Polar Spongioblastomas; Spongioblastoma, Polar; Spongioblastomas, Polar
SNOMED CT: Polar spongioblastoma (12943006); Spongioblastoma polare (12943006); Primitive polar spongioblastoma (12943006)

Definition

A lesion characterized by the presence of neoplastic neuroepithelial cells with palisading nuclei. This lesion implies a morphologic growth pattern and it is not considered a clinicopathological entity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolar Spongioblastoma

Professional guidelines

PubMed

Glioblastoma: clinical presentation, diagnosis, and management.
McKinnon C, Nandhabalan M, Murray SA, Plaha P
BMJ 2021 Jul 14;374:n1560. doi: 10.1136/bmj.n1560. PMID: 34261630
EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.
Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn JC, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi ME, Jakola AS, Platten M, Roth P, Rudà R, Short S, Smits M, Taphoorn MJB, von Deimling A, Westphal M, Soffietti R, Reifenberger G, Wick W
Nat Rev Clin Oncol 2021 Mar;18(3):170-186. Epub 2020 Dec 8 doi: 10.1038/s41571-020-00447-z. PMID: 33293629Free PMC Article
EANO guidelines for the diagnosis and treatment of ependymal tumors.
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article

Recent clinical studies

Etiology

Astroblastoma - reviewing literature and one case report.
Teleanu DM, Ilieşiu A, Bălaşa AF, Teleanu RI, Bogaciu NŞ
Rom J Morphol Embryol 2018;59(4):1239-1245. PMID: 30845307
Third ventricle gliomas. Report of 7 cases with benign clinical behaviour.
Casotto A, Buoncristiani P, Signorini E, Giordana MT
Acta Neurochir (Wien) 1985;74(1-2):43-8. doi: 10.1007/BF01413276. PMID: 3976445

Diagnosis

Astroblastoma - reviewing literature and one case report.
Teleanu DM, Ilieşiu A, Bălaşa AF, Teleanu RI, Bogaciu NŞ
Rom J Morphol Embryol 2018;59(4):1239-1245. PMID: 30845307
A case of unclassified high-grade glioma with polar spongioblastoma pattern.
Fukushima S, Narita Y, Shinomiya A, Ohno M, Miyakita Y, Okita Y, Hanakawa K, Ide T, Kayama T, Shibui S, Tsuda H
Neuropathology 2012 Dec;32(6):604-10. Epub 2012 Mar 7 doi: 10.1111/j.1440-1789.2012.01303.x. PMID: 22393945
Is polar spongioblastoma a tumor entity?
Schiffer D, Cravioto H, Giordana MT, Migheli A, Pezzulo T, Vigliani MC
J Neurosurg 1993 Apr;78(4):587-91. doi: 10.3171/jns.1993.78.4.0587. PMID: 8450332
Pathology--trends and pitfalls in histologic diagnosis, immunopathology, and applications of oncogene research.
Burger PC, Fuller GN
Neurol Clin 1991 May;9(2):249-71. PMID: 1682793
Palisading pattern in cerebral neuroblastoma mimicking the primitive polar spongioblastoma. An ultrastructural study.
Langford LA, Camel MH
Acta Neuropathol 1987;73(2):153-9. doi: 10.1007/BF00693781. PMID: 3604582

Therapy

Polar spongioblastoma of the spinal cord: a case report.
Fuller C, Helton K, Dalton J, Fouladi M, Kun L, Burger P
Pediatr Dev Pathol 2006 Jan-Feb;9(1):75-80. Epub 2006 Apr 4 doi: 10.2350/08-05-0099.1. PMID: 16808641

Prognosis

Anaplastic changes of diffuse leptomeningeal glioneuronal tumor with polar spongioblastoma pattern.
Yamasaki T, Sakai N, Shinmura K, Kawaji H, Koizumi S, Samashima T, Namba H
Brain Tumor Pathol 2018 Oct;35(4):209-216. Epub 2018 Jul 26 doi: 10.1007/s10014-018-0326-z. PMID: 30051174
Intratumoral distribution of 1p loss in oligodendroglial tumors.
Kros JM, van der Weiden M, Zheng PP, Hop WC, van den Bent MJ, Kouwenhoven MC
J Neuropathol Exp Neurol 2007 Dec;66(12):1118-23. doi: 10.1097/nen.0b013e31815c254d. PMID: 18090920
Polar spongioblastoma of the spinal cord: a case report.
Fuller C, Helton K, Dalton J, Fouladi M, Kun L, Burger P
Pediatr Dev Pathol 2006 Jan-Feb;9(1):75-80. Epub 2006 Apr 4 doi: 10.2350/08-05-0099.1. PMID: 16808641
Pathology--trends and pitfalls in histologic diagnosis, immunopathology, and applications of oncogene research.
Burger PC, Fuller GN
Neurol Clin 1991 May;9(2):249-71. PMID: 1682793
Embryonal central neuroepithelial tumors and their differentiating potential. A cytogenetic view of a complex neuro-oncological problem.
Rubinstein LJ
J Neurosurg 1985 Jun;62(6):795-805. doi: 10.3171/jns.1985.62.6.0795. PMID: 2987439

Clinical prediction guides

Polar spongioblastoma: A high-grade glioma that does not contain the IDH1 mutation or 1p/19q LOH.
Nagaishi M, Tanaka Y, Iwatate K, Yokoo H, Ueki K, Hyodo A, Nakazato Y
Neuropathology 2010 Oct;30(5):547-52. doi: 10.1111/j.1440-1789.2009.01087.x. PMID: 20102524
Intratumoral distribution of 1p loss in oligodendroglial tumors.
Kros JM, van der Weiden M, Zheng PP, Hop WC, van den Bent MJ, Kouwenhoven MC
J Neuropathol Exp Neurol 2007 Dec;66(12):1118-23. doi: 10.1097/nen.0b013e31815c254d. PMID: 18090920
Glial hyaluronate-binding protein in polar spongioblastoma.
Bignami A, Adelman LS, Perides G, Dahl D
J Neuropathol Exp Neurol 1989 Mar;48(2):187-96. doi: 10.1097/00005072-198903000-00006. PMID: 2466108
Evolution and outcome in malignant astroglial neoplasms of the cerebellum.
Steinberg GK, Shuer LM, Conley FK, Hanbery JW
J Neurosurg 1985 Jan;62(1):9-17. doi: 10.3171/jns.1985.62.1.0009. PMID: 3964859

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