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Cocaine dependence

MedGen UID:
154705
•Concept ID:
C0600427
•
Mental or Behavioral Dysfunction
Synonyms: Addiction, Cocaine; Cocaine Addiction; Cocaine Dependence; Dependence, Cocaine; Dependences, Cocaine
SNOMED CT: Cocaine dependence (31956009)
 
HPO: HP:0033513
Monarch Initiative: MONDO:0005186

Definition

Addiction to cocaine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCocaine dependence

Professional guidelines

PubMed

Disulfiram for the treatment of cocaine dependence.
Traccis F, Minozzi S, Trogu E, Vacca R, Vecchi S, Pani PP, Agabio R
Cochrane Database Syst Rev 2024 Jan 5;1(1):CD007024. doi: 10.1002/14651858.CD007024.pub3. PMID: 38180268Free PMC Article
Expanding treatment options for cocaine dependence.
Brady KT
Am J Psychiatry 2009 Nov;166(11):1209-10. doi: 10.1176/appi.ajp.2009.09091312. PMID: 19884233
New medications for the treatment of cocaine dependence.
Kampman KM
Ann Ist Super Sanita 2009;45(2):109-15. PMID: 19636162

Recent clinical studies

Etiology

Binge drinking in early adulthood: A machine learning approach.
Dell NA, Prasad Srivastava S, Vaughn MG, Salas-Wright C, Hai AH, Qian Z
Addict Behav 2022 Jan;124:107122. Epub 2021 Sep 20 doi: 10.1016/j.addbeh.2021.107122. PMID: 34598011
Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence.
Crits-Christoph P, Wadden S, Gaines A, Rieger A, Gallop R, McKay JR, Gibbons MBC
J Subst Abuse Treat 2018 Sep;92:46-50. Epub 2018 Jun 21 doi: 10.1016/j.jsat.2018.06.010. PMID: 30032944Free PMC Article
Reboxetine in clinical practice: a review.
Sepede G, Corbo M, Fiori F, Martinotti G
Clin Ter 2012 Jul;163(4):e255-62. PMID: 23007832
Genetics of addictions.
Hartz SM, Bierut LJ
Clin Lab Med 2010 Dec;30(4):847-64. doi: 10.1016/j.cll.2010.07.005. PMID: 20832656Free PMC Article
Genetics of addictions.
Hartz SM, Bierut LJ
Psychiatr Clin North Am 2010 Mar;33(1):107-24. doi: 10.1016/j.psc.2009.10.003. PMID: 20159342Free PMC Article

Diagnosis

Depression and cocaine dependence.
López A, Becoña E
Psychol Rep 2007 Apr;100(2):520-4. doi: 10.2466/pr0.100.2.520-524. PMID: 17564228
The effects and management of crack cocaine dependence.
McClelland GT
Nurs Times 2005 Jul 19-25;101(29):26-7. PMID: 16052938
Cocaine dependence with and without comorbid depression: a comparison of patient characteristics.
Schmitz JM, Stotts AL, Averill PM, Rothfleisch JM, Bailley SE, Sayre SL, Grabowski J
Drug Alcohol Depend 2000 Aug 1;60(2):189-98. doi: 10.1016/s0376-8716(99)00157-x. PMID: 10940546
Cocaine-induced psychosis.
Brady KT, Lydiard RB, Malcolm R, Ballenger JC
J Clin Psychiatry 1991 Dec;52(12):509-12. PMID: 1752853
The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence.
Khantzian EJ
Am J Psychiatry 1985 Nov;142(11):1259-64. doi: 10.1176/ajp.142.11.1259. PMID: 3904487

Therapy

Varenicline Use for Cocaine Dependence.
Gupta A
Prim Care Companion CNS Disord 2023 May 30;25(3) doi: 10.4088/PCC.22l03375. PMID: 37276057
Anti-cocaine Vaccine Development: Where Are We Now and Where Are We Going?
Stephenson RJ, Toth I
J Med Chem 2023 Jun 8;66(11):7086-7100. Epub 2023 May 25 doi: 10.1021/acs.jmedchem.3c00366. PMID: 37227096
Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence.
Crits-Christoph P, Wadden S, Gaines A, Rieger A, Gallop R, McKay JR, Gibbons MBC
J Subst Abuse Treat 2018 Sep;92:46-50. Epub 2018 Jun 21 doi: 10.1016/j.jsat.2018.06.010. PMID: 30032944Free PMC Article
WITHDRAWN: Anticonvulsants for cocaine dependence.
Minozzi S, Amato L, Davoli M, Farrell MF, Lima Reisser AA, Pani PP, Silva de Lima M, Soares BG, Vecchi S
Cochrane Database Syst Rev 2015 Mar 3;(3):CD006754. doi: 10.1002/14651858.CD006754.pub3. PMID: 25731153
Pharmacologic approaches to the treatment of cocaine dependence.
Taylor WA, Gold MS
West J Med 1990 May;152(5):573-7. PMID: 1971975Free PMC Article

Prognosis

Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence.
Crits-Christoph P, Wadden S, Gaines A, Rieger A, Gallop R, McKay JR, Gibbons MBC
J Subst Abuse Treat 2018 Sep;92:46-50. Epub 2018 Jun 21 doi: 10.1016/j.jsat.2018.06.010. PMID: 30032944Free PMC Article
Global statistics on alcohol, tobacco and illicit drug use: 2017 status report.
Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J, Giovino GA, West R, Hall W, Griffiths P, Ali R, Gowing L, Marsden J, Ferrari AJ, Grebely J, Farrell M, Degenhardt L
Addiction 2018 Oct;113(10):1905-1926. Epub 2018 Jun 4 doi: 10.1111/add.14234. PMID: 29749059
Topiramate in the treatment of cocaine use disorder.
Prince V, Bowling KC
Am J Health Syst Pharm 2018 Jan 1;75(1):e13-e22. doi: 10.2146/ajhp160542. PMID: 29273608
Early abstinence in cocaine dependence: influence of comorbid major depression.
Rubin E, Aharonovich E, Bisaga A, Levin FR, Raby WN, Nunes EV
Am J Addict 2007 Jul-Aug;16(4):283-90. doi: 10.1080/10550490701389880. PMID: 17661196
Day treatment for cocaine dependence: incremental utility over outpatient counseling and voucher incentives.
Marlowe DB, Kirby KC, Festinger DS, Merikle EP, Tran GQ, Platt JJ
Addict Behav 2003 Mar;28(2):387-98. doi: 10.1016/s0306-4603(01)00248-9. PMID: 12573690

Clinical prediction guides

Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence.
Crits-Christoph P, Wadden S, Gaines A, Rieger A, Gallop R, McKay JR, Gibbons MBC
J Subst Abuse Treat 2018 Sep;92:46-50. Epub 2018 Jun 21 doi: 10.1016/j.jsat.2018.06.010. PMID: 30032944Free PMC Article
How many treatment sessions and patients are needed to create a stable score of adherence and competence in the treatment of cocaine dependence?
Dennhag I, Gibbons MB, Barber JP, Gallop R, Crits-Christoph P
Psychother Res 2012;22(4):475-88. Epub 2012 Mar 26 doi: 10.1080/10503307.2012.674790. PMID: 22449079Free PMC Article
Depression and cocaine dependence.
López A, Becoña E
Psychol Rep 2007 Apr;100(2):520-4. doi: 10.2466/pr0.100.2.520-524. PMID: 17564228
Perfusion abnormalities and decision making in cocaine dependence.
Tucker KA, Potenza MN, Beauvais JE, Browndyke JN, Gottschalk PC, Kosten TR
Biol Psychiatry 2004 Oct 1;56(7):527-30. doi: 10.1016/j.biopsych.2004.06.031. PMID: 15450790
The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence.
Khantzian EJ
Am J Psychiatry 1985 Nov;142(11):1259-64. doi: 10.1176/ajp.142.11.1259. PMID: 3904487

Recent systematic reviews

Modafinil Treatment of Cocaine Dependence: A Systematic Review and Meta-Analysis.
Sangroula D, Motiwala F, Wagle B, Shah VC, Hagi K, Lippmann S
Subst Use Misuse 2017 Aug 24;52(10):1292-1306. Epub 2017 Mar 28 doi: 10.1080/10826084.2016.1276597. PMID: 28350194
Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials.
Singh M, Keer D, Klimas J, Wood E, Werb D
Addiction 2016 Aug;111(8):1337-46. Epub 2016 Apr 1 doi: 10.1111/add.13328. PMID: 26826006
Anticonvulsants for cocaine dependence.
Minozzi S, Cinquini M, Amato L, Davoli M, Farrell MF, Pani PP, Vecchi S
Cochrane Database Syst Rev 2015 Apr 17;2015(4):CD006754. doi: 10.1002/14651858.CD006754.pub4. PMID: 25882271Free PMC Article
WITHDRAWN: Anticonvulsants for cocaine dependence.
Minozzi S, Amato L, Davoli M, Farrell MF, Lima Reisser AA, Pani PP, Silva de Lima M, Soares BG, Vecchi S
Cochrane Database Syst Rev 2015 Mar 3;(3):CD006754. doi: 10.1002/14651858.CD006754.pub3. PMID: 25731153
Antipsychotic drugs in cocaine dependence: a systematic review and meta-analysis.
Alvarez Y, Pérez-Mañá C, Torrens M, Farré M
J Subst Abuse Treat 2013 Jul;45(1):1-10. Epub 2013 Jan 26 doi: 10.1016/j.jsat.2012.12.013. PMID: 23357467

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