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Cocaine dependence

MedGen UID:
154705
•Concept ID:
C0600427
•
Mental or Behavioral Dysfunction
Synonyms: Addiction, Cocaine; Cocaine Addiction; Cocaine Dependence; Dependence, Cocaine; Dependences, Cocaine
SNOMED CT: Cocaine dependence (31956009)
 
HPO: HP:0033513
Monarch Initiative: MONDO:0005186

Definition

Addiction to cocaine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCocaine dependence

Professional guidelines

PubMed

Modafinil Treatment of Cocaine Dependence: A Systematic Review and Meta-Analysis.
Sangroula D, Motiwala F, Wagle B, Shah VC, Hagi K, Lippmann S
Subst Use Misuse 2017 Aug 24;52(10):1292-1306. Epub 2017 Mar 28 doi: 10.1080/10826084.2016.1276597. PMID: 28350194
Cocaine dependence and stroke: pathogenesis and management.
Siniscalchi A, Bonci A, Mercuri NB, De Siena A, De Sarro G, Malferrari G, Diana M, Gallelli L
Curr Neurovasc Res 2015;12(2):163-72. doi: 10.2174/1567202612666150305110144. PMID: 25742568
Psychostimulant treatment of cocaine dependence.
Mariani JJ, Levin FR
Psychiatr Clin North Am 2012 Jun;35(2):425-39. Epub 2012 Apr 26 doi: 10.1016/j.psc.2012.03.012. PMID: 22640764Free PMC Article

Recent clinical studies

Etiology

Varenicline for the Treatment of Cocaine Dependence.
Lynch KG, Plebani J, Spratt K, Morales M, Tamminga M, Feibush P, Kampman KM
J Addict Med 2022 Mar-Apr 01;16(2):157-163. doi: 10.1097/ADM.0000000000000842. PMID: 33840773Free PMC Article
Antipsychotic medications for cocaine dependence.
Indave BI, Minozzi S, Pani PP, Amato L
Cochrane Database Syst Rev 2016 Mar 19;3(3):CD006306. doi: 10.1002/14651858.CD006306.pub3. PMID: 26992929Free PMC Article
Anticonvulsants for cocaine dependence.
Minozzi S, Cinquini M, Amato L, Davoli M, Farrell MF, Pani PP, Vecchi S
Cochrane Database Syst Rev 2015 Apr 17;2015(4):CD006754. doi: 10.1002/14651858.CD006754.pub4. PMID: 25882271Free PMC Article
Genetics of addictions.
Hartz SM, Bierut LJ
Clin Lab Med 2010 Dec;30(4):847-64. doi: 10.1016/j.cll.2010.07.005. PMID: 20832656Free PMC Article
Genetics of addictions.
Hartz SM, Bierut LJ
Psychiatr Clin North Am 2010 Mar;33(1):107-24. doi: 10.1016/j.psc.2009.10.003. PMID: 20159342Free PMC Article

Diagnosis

Topiramate in the treatment of cocaine use disorder.
Prince V, Bowling KC
Am J Health Syst Pharm 2018 Jan 1;75(1):e13-e22. doi: 10.2146/ajhp160542. PMID: 29273608
Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials.
Singh M, Keer D, Klimas J, Wood E, Werb D
Addiction 2016 Aug;111(8):1337-46. Epub 2016 Apr 1 doi: 10.1111/add.13328. PMID: 26826006
Antidepressants for cocaine dependence and problematic cocaine use.
Pani PP, Trogu E, Vecchi S, Amato L
Cochrane Database Syst Rev 2011 Dec 7;(12):CD002950. doi: 10.1002/14651858.CD002950.pub3. PMID: 22161371
Treatment of cocaine dependence and depression.
Rounsaville BJ
Biol Psychiatry 2004 Nov 15;56(10):803-9. doi: 10.1016/j.biopsych.2004.05.009. PMID: 15556126
Cocaine-induced psychosis.
Brady KT, Lydiard RB, Malcolm R, Ballenger JC
J Clin Psychiatry 1991 Dec;52(12):509-12. PMID: 1752853

Therapy

Varenicline for the Treatment of Cocaine Dependence.
Lynch KG, Plebani J, Spratt K, Morales M, Tamminga M, Feibush P, Kampman KM
J Addict Med 2022 Mar-Apr 01;16(2):157-163. doi: 10.1097/ADM.0000000000000842. PMID: 33840773Free PMC Article
Antipsychotic medications for cocaine dependence.
Indave BI, Minozzi S, Pani PP, Amato L
Cochrane Database Syst Rev 2016 Mar 19;3(3):CD006306. doi: 10.1002/14651858.CD006306.pub3. PMID: 26992929Free PMC Article
Anticonvulsants for cocaine dependence.
Minozzi S, Cinquini M, Amato L, Davoli M, Farrell MF, Pani PP, Vecchi S
Cochrane Database Syst Rev 2015 Apr 17;2015(4):CD006754. doi: 10.1002/14651858.CD006754.pub4. PMID: 25882271Free PMC Article
Cocaine dependence and stroke: pathogenesis and management.
Siniscalchi A, Bonci A, Mercuri NB, De Siena A, De Sarro G, Malferrari G, Diana M, Gallelli L
Curr Neurovasc Res 2015;12(2):163-72. doi: 10.2174/1567202612666150305110144. PMID: 25742568
Antidepressants for cocaine dependence and problematic cocaine use.
Pani PP, Trogu E, Vecchi S, Amato L
Cochrane Database Syst Rev 2011 Dec 7;(12):CD002950. doi: 10.1002/14651858.CD002950.pub3. PMID: 22161371

Prognosis

Suicide risk among persons living with HIV.
Brown LA, Majeed I, Mu W, McCann J, Durborow S, Chen S, Blank MB
AIDS Care 2021 May;33(5):616-622. Epub 2020 Aug 3 doi: 10.1080/09540121.2020.1801982. PMID: 32741212Free PMC Article
Cocaine dependence: "Side effects" and syndrome formation within 1-12 months after first cocaine use.
Chandra M, Anthony JC
Drug Alcohol Depend 2020 Jan 1;206:107717. Epub 2019 Nov 4 doi: 10.1016/j.drugalcdep.2019.107717. PMID: 31753734
Global statistics on alcohol, tobacco and illicit drug use: 2017 status report.
Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J, Giovino GA, West R, Hall W, Griffiths P, Ali R, Gowing L, Marsden J, Ferrari AJ, Grebely J, Farrell M, Degenhardt L
Addiction 2018 Oct;113(10):1905-1926. Epub 2018 Jun 4 doi: 10.1111/add.14234. PMID: 29749059
Topiramate in the treatment of cocaine use disorder.
Prince V, Bowling KC
Am J Health Syst Pharm 2018 Jan 1;75(1):e13-e22. doi: 10.2146/ajhp160542. PMID: 29273608
Self-administration of cocaine, cannabis and heroin in the human laboratory: benefits and pitfalls.
Haney M
Addict Biol 2009 Jan;14(1):9-21. Epub 2008 Oct 9 doi: 10.1111/j.1369-1600.2008.00121.x. PMID: 18855806Free PMC Article

Clinical prediction guides

Cocaine-induced Changes in the Expression of NMDA Receptor Subunits.
Smaga I, Sanak M, Filip M
Curr Neuropharmacol 2019;17(11):1039-1055. doi: 10.2174/1570159X17666190617101726. PMID: 31204625Free PMC Article
Topiramate in the treatment of cocaine use disorder.
Prince V, Bowling KC
Am J Health Syst Pharm 2018 Jan 1;75(1):e13-e22. doi: 10.2146/ajhp160542. PMID: 29273608
Reward Circuitry in Addiction.
Cooper S, Robison AJ, Mazei-Robison MS
Neurotherapeutics 2017 Jul;14(3):687-697. doi: 10.1007/s13311-017-0525-z. PMID: 28324454Free PMC Article
Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials.
Singh M, Keer D, Klimas J, Wood E, Werb D
Addiction 2016 Aug;111(8):1337-46. Epub 2016 Apr 1 doi: 10.1111/add.13328. PMID: 26826006
Cocaine dependence.
Gawin FH, Ellinwood EH Jr
Annu Rev Med 1989;40:149-61. doi: 10.1146/annurev.me.40.020189.001053. PMID: 2658744

Recent systematic reviews

Modafinil Treatment of Cocaine Dependence: A Systematic Review and Meta-Analysis.
Sangroula D, Motiwala F, Wagle B, Shah VC, Hagi K, Lippmann S
Subst Use Misuse 2017 Aug 24;52(10):1292-1306. Epub 2017 Mar 28 doi: 10.1080/10826084.2016.1276597. PMID: 28350194
Antipsychotic medications for cocaine dependence.
Indave BI, Minozzi S, Pani PP, Amato L
Cochrane Database Syst Rev 2016 Mar 19;3(3):CD006306. doi: 10.1002/14651858.CD006306.pub3. PMID: 26992929Free PMC Article
Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials.
Singh M, Keer D, Klimas J, Wood E, Werb D
Addiction 2016 Aug;111(8):1337-46. Epub 2016 Apr 1 doi: 10.1111/add.13328. PMID: 26826006
Anticonvulsants for cocaine dependence.
Minozzi S, Cinquini M, Amato L, Davoli M, Farrell MF, Pani PP, Vecchi S
Cochrane Database Syst Rev 2015 Apr 17;2015(4):CD006754. doi: 10.1002/14651858.CD006754.pub4. PMID: 25882271Free PMC Article
Antidepressants for cocaine dependence and problematic cocaine use.
Pani PP, Trogu E, Vecchi S, Amato L
Cochrane Database Syst Rev 2011 Dec 7;(12):CD002950. doi: 10.1002/14651858.CD002950.pub3. PMID: 22161371

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