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Hepatic granuloma

MedGen UID:
155428
•Concept ID:
C0745754
•
Disease or Syndrome
Synonyms: Hepatic Granuloma; hepatic granuloma; Liver Granuloma
SNOMED CT: Hepatic granuloma (714253009)
 
Monarch Initiative: MONDO:0006241

Definition

A granuloma located in the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatic granuloma

Professional guidelines

PubMed

The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
Chen Q, Zhang J, Zheng T, Chen H, Nie H, Zheng B, Gong Q
Parasit Vectors 2019 Dec 30;12(1):611. doi: 10.1186/s13071-019-3866-0. PMID: 31888743Free PMC Article

Recent clinical studies

Etiology

Sodium butyrate ameliorates Schistosoma japonicum-induced liver fibrosis by inhibiting HMGB1 expression.
Chen H, Li G, Zhang J, Zheng T, Chen Q, Zhang Y, Yang F, Wang C, Nie H, Zheng B, Gong Q
Exp Parasitol 2021 Dec;231:108171. Epub 2021 Nov 2 doi: 10.1016/j.exppara.2021.108171. PMID: 34736899
Causes of hepatic granuloma: a 12-year single center experience from southern Iran.
Geramizadeh B, Jahangiri R, Moradi E
Arch Iran Med 2011 Jul;14(4):288-9. PMID: 21726107
Hepatic granulomas: a clinicopathologic analysis of 86 cases.
Turhan N, Kurt M, Ozderin YO, Kurt OK
Pathol Res Pract 2011 Jun 15;207(6):359-65. Epub 2011 Apr 30 doi: 10.1016/j.prp.2011.03.003. PMID: 21531083
Hepatic granuloma: decreasing trend in a high-incidence area.
Sanai FM, Ashraf S, Abdo AA, Satti MB, Batwa F, Al-Husseini H, Saleh AM, Bzeizi KI
Liver Int 2008 Dec;28(10):1402-7. doi: 10.1111/j.1478-3231.2008.01837.x. PMID: 18694402
Hepatobiliary tuberculosis in western India.
Amarapurkar DN, Patel ND, Amarapurkar AD
Indian J Pathol Microbiol 2008 Apr-Jun;51(2):175-81. doi: 10.4103/0377-4929.41644. PMID: 18603675

Diagnosis

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
A rare cause of granulomatous hepatitis: Tularemia.
Kocabaş E, Özgür Gündeşlioğlu Ö, Kılıç Çil M, Çay Ü, Doran F, Soyupak S
J Infect Public Health 2020 Jul;13(7):1003-1005. Epub 2020 Jan 11 doi: 10.1016/j.jiph.2019.12.007. PMID: 31937491
The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
Chen Q, Zhang J, Zheng T, Chen H, Nie H, Zheng B, Gong Q
Parasit Vectors 2019 Dec 30;12(1):611. doi: 10.1186/s13071-019-3866-0. PMID: 31888743Free PMC Article
Enfermedad granulomatosa hepática.
Ortiz-Brizuela E, Azamar-Llamas D, Mora JD, Guerrero-Castillo JI, Martínez-Benítez B, Sifuentes-Osornio J
Gac Med Mex 2019;155(3):266-275. doi: 10.24875/GMM.18004327. PMID: 31219474
Hepatobiliary tuberculosis in western India.
Amarapurkar DN, Patel ND, Amarapurkar AD
Indian J Pathol Microbiol 2008 Apr-Jun;51(2):175-81. doi: 10.4103/0377-4929.41644. PMID: 18603675

Therapy

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
Sodium butyrate ameliorates Schistosoma japonicum-induced liver fibrosis by inhibiting HMGB1 expression.
Chen H, Li G, Zhang J, Zheng T, Chen Q, Zhang Y, Yang F, Wang C, Nie H, Zheng B, Gong Q
Exp Parasitol 2021 Dec;231:108171. Epub 2021 Nov 2 doi: 10.1016/j.exppara.2021.108171. PMID: 34736899
The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
Chen Q, Zhang J, Zheng T, Chen H, Nie H, Zheng B, Gong Q
Parasit Vectors 2019 Dec 30;12(1):611. doi: 10.1186/s13071-019-3866-0. PMID: 31888743Free PMC Article
Taurine drinking ameliorates hepatic granuloma and fibrosis in mice infected with Schistosoma japonicum.
Yu YR, Ni XQ, Huang J, Zhu YH, Qi YF
Int J Parasitol Drugs Drug Resist 2016 Apr;6(1):35-43. Epub 2016 Jan 14 doi: 10.1016/j.ijpddr.2016.01.003. PMID: 27054062Free PMC Article
Lessons from other diseases: granulomatous inflammation in leishmaniasis.
Kaye PM, Beattie L
Semin Immunopathol 2016 Mar;38(2):249-60. Epub 2015 Dec 17 doi: 10.1007/s00281-015-0548-7. PMID: 26678994Free PMC Article

Prognosis

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
Hepatic granuloma in Turkish adults: a report of 13 cases.
Onal IK, Ersoy O, Aydinli M, Yonem O, Harmanci O, Sokmensuer C, Bayraktar Y
Eur J Intern Med 2008 Nov;19(7):527-30. Epub 2008 Mar 11 doi: 10.1016/j.ejim.2008.01.012. PMID: 19013382
Hepatic granuloma: decreasing trend in a high-incidence area.
Sanai FM, Ashraf S, Abdo AA, Satti MB, Batwa F, Al-Husseini H, Saleh AM, Bzeizi KI
Liver Int 2008 Dec;28(10):1402-7. doi: 10.1111/j.1478-3231.2008.01837.x. PMID: 18694402
Prevalence of hepatic granulomas in chronic hepatitis B.
Tahan V, Ozaras R, Lacevic N, Ozden E, Yemisen M, Ozdogan O, Mert A, Tabak F, Avsar E, Celikel CA, Ozbay G, Kalayci C, Senturk H, Tozun N
Dig Dis Sci 2004 Oct;49(10):1575-7. doi: 10.1023/b:ddas.0000043366.18578.15. PMID: 15573907
The prevalence of hepatic granulomas in chronic hepatitis C.
Ozaras R, Tahan V, Mert A, Uraz S, Kanat M, Tabak F, Avsar E, Ozbay G, Celikel CA, Tozun N, Senturk H
J Clin Gastroenterol 2004 May-Jun;38(5):449-52. doi: 10.1097/00004836-200405000-00011. PMID: 15100526

Clinical prediction guides

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
Spatial and temporal transcriptomics of Schistosoma japonicum-induced hepatic granuloma formation reveals novel roles for neutrophils.
Chuah C, Jones MK, Burke ML, Owen HC, Anthony BJ, McManus DP, Ramm GA, Gobert GN
J Leukoc Biol 2013 Aug;94(2):353-65. Epub 2013 May 24 doi: 10.1189/jlb.1212653. PMID: 23709687
Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages.
Chu D, Du M, Hu X, Wu Q, Shen J
Parasitology 2011 Sep;138(10):1259-71. Epub 2011 Aug 3 doi: 10.1017/S0031182011001065. PMID: 21810309
Hepatic granulomas: a clinicopathologic analysis of 86 cases.
Turhan N, Kurt M, Ozderin YO, Kurt OK
Pathol Res Pract 2011 Jun 15;207(6):359-65. Epub 2011 Apr 30 doi: 10.1016/j.prp.2011.03.003. PMID: 21531083
The role of cytokines in the formation of the schistosome egg granuloma.
Boros DL
Immunobiology 1994 Oct;191(4-5):441-50. doi: 10.1016/S0171-2985(11)80450-X. PMID: 7713558

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