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Malignant tumor of neck

MedGen UID:
155434
Concept ID:
C0746787
Neoplastic Process
Synonyms: Cancer of Neck; Cancer of the Neck; Cancer, Neck; Cancers, Neck; Neck Cancer; Neck Cancers
SNOMED CT: Malignant tumor of neck (363489000)
 
Monarch Initiative: MONDO:0021310

Definition

A primary or metastatic malignant neoplasm that affects the anatomic structures of the neck region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant tumor of neck

Professional guidelines

PubMed

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Hanemann CO, Kalamarides M, Kehrer-Sawatzki H, Korf BR, Mautner VF, MacCollin M, Papi L, Rauen KA, Riccardi V, Schorry E, Smith MJ, Stemmer-Rachamimov A, Stevenson DA, Ullrich NJ, Viskochil D, Wimmer K, Yohay K; International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Huson SM, Wolkenstein P, Evans DG
Genet Med 2022 Sep;24(9):1967-1977. Epub 2022 Jun 9 doi: 10.1016/j.gim.2022.05.007. PMID: 35674741
Filetti S, Durante C, Hartl D, Leboulleux S, Locati LD, Newbold K, Papotti MG, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400. PMID: 31549998

Recent clinical studies

Etiology

Tan Y, Wang Z, Xu M, Li B, Huang Z, Qin S, Nice EC, Tang J, Huang C
Int J Oral Sci 2023 Sep 22;15(1):44. doi: 10.1038/s41368-023-00249-w. PMID: 37736748Free PMC Article
Schinke H, Shi E, Lin Z, Quadt T, Kranz G, Zhou J, Wang H, Hess J, Heuer S, Belka C, Zitzelsberger H, Schumacher U, Genduso S, Riecken K, Gao Y, Wu Z, Reichel CA, Walz C, Canis M, Unger K, Baumeister P, Pan M, Gires O
Mol Cancer 2022 Sep 8;21(1):178. doi: 10.1186/s12943-022-01646-1. PMID: 36076232Free PMC Article
Valero C, Ganly I
J Oral Pathol Med 2022 Nov;51(10):897-903. Epub 2022 Feb 23 doi: 10.1111/jop.13286. PMID: 35178777
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Rivera C
Int J Clin Exp Pathol 2015;8(9):11884-94. Epub 2015 Sep 1 PMID: 26617944Free PMC Article

Diagnosis

Valero C, Ganly I
J Oral Pathol Med 2022 Nov;51(10):897-903. Epub 2022 Feb 23 doi: 10.1111/jop.13286. PMID: 35178777
Shen Y, Liu J, Zhang L, Dong S, Zhang J, Liu Y, Zhou H, Dong W
Biomed Res Int 2019;2019:7376034. Epub 2019 Aug 7 doi: 10.1155/2019/7376034. PMID: 31485443Free PMC Article
Wasserman JK, Gravel D, Purgina B
Head Neck Pathol 2018 Jun;12(2):261-268. Epub 2017 Oct 4 doi: 10.1007/s12105-017-0860-8. PMID: 28980142Free PMC Article
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Wong BL, Lee VN, Tikka T, Kim D, Dwivedi RC
Crit Rev Oncol Hematol 2016 Aug;104:156-68. Epub 2016 Jun 16 doi: 10.1016/j.critrevonc.2016.06.005. PMID: 27365122

Therapy

Bourhis J, Burtness B, Licitra LF, Nutting C, Schoenfeld JD, Omar M, Bouisset F, Nauwelaerts H, Urfer Y, Zanna C, Cohen EE
Future Oncol 2022 May;18(14):1669-1678. Epub 2022 Feb 17 doi: 10.2217/fon-2021-1634. PMID: 35172587
Li X, Lee A, Cohen MA, Sherman EJ, Lee NY
Oral Oncol 2020 Nov;110:104879. Epub 2020 Jul 7 doi: 10.1016/j.oraloncology.2020.104879. PMID: 32650256
Guigay J, Le Caer H, Ortholan C, Aupérin A, Michel C, Mertens C
Curr Opin Oncol 2019 May;31(3):152-159. doi: 10.1097/CCO.0000000000000526. PMID: 30985496
Tseng M, Tan TH, Zheng H, Soon YY, Tey J
Head Neck 2018 Aug;40(8):1854-1860. Epub 2018 Mar 25 doi: 10.1002/hed.25133. PMID: 29575476
Bernier J, Cooper JS, Pajak TF, van Glabbeke M, Bourhis J, Forastiere A, Ozsahin EM, Jacobs JR, Jassem J, Ang KK, Lefèbvre JL
Head Neck 2005 Oct;27(10):843-50. doi: 10.1002/hed.20279. PMID: 16161069

Prognosis

Xu Y, Xu G, Liu Z, Duan J, Lin Y, Zhu J, Baklaushev VP, Chekhonin VP, Peltzer K, Wang G, Wang X, Zhang C
Acta Neurochir (Wien) 2021 Feb;163(2):521-529. Epub 2020 Nov 21 doi: 10.1007/s00701-020-04647-5. PMID: 33219865
Han S, Yin X, Xu W, Wang Y, Han W
J Craniofac Surg 2020 Mar/Apr;31(2):e189-e192. doi: 10.1097/SCS.0000000000006162. PMID: 31934973
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A
Head Neck 2019 Feb;41(2):511-521. Epub 2018 Jun 26 doi: 10.1002/hed.25172. PMID: 29947111
Qaisi M, Eid I
Oral Maxillofac Surg Clin North Am 2016 Feb;28(1):11-9. doi: 10.1016/j.coms.2015.07.008. PMID: 26614697
Stern JS, Ginat DT, Nicholas JL, Ryan ME
Otolaryngol Clin North Am 2015 Feb;48(1):225-46. doi: 10.1016/j.otc.2014.09.015. PMID: 25439556

Clinical prediction guides

Boumaza K, Michel G, Salaud C, Bossard C, Espitalier F, Malard O
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Nov;136(6):455-460. Epub 2019 Sep 16 doi: 10.1016/j.anorl.2019.09.005. PMID: 31537489
Saluja TS, Iyer J, Singh SK
Oral Oncol 2019 Aug;95:100-105. Epub 2019 Jun 13 doi: 10.1016/j.oraloncology.2019.06.010. PMID: 31345375
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Nelke KH, Pawlak W, Gerber H, Leszczyszyn J
Adv Clin Exp Med 2014 Nov-Dec;23(6):1019-27. doi: 10.17219/acem/37361. PMID: 25618131

Recent systematic reviews

Kuhn MA, Gillespie MB, Ishman SL, Ishii LE, Brody R, Cohen E, Dhar SI, Hutcheson K, Jefferson G, Johnson F, Rameau A, Sher D, Starmer H, Strohl M, Ulmer K, Vaitaitis V, Begum S, Batjargal M, Dhepyasuwan N
Otolaryngol Head Neck Surg 2023 Apr;168(4):571-592. doi: 10.1002/ohn.302. PMID: 36965195
Bossola M, Antocicco M, Pepe G
JPEN J Parenter Enteral Nutr 2022 Aug;46(6):1258-1269. Epub 2022 May 22 doi: 10.1002/jpen.2360. PMID: 35244947
Mäkitie AA, Alabi RO, Orell H, Youssef O, Almangush A, Homma A, Takes RP, López F, de Bree R, Rodrigo JP, Ferlito A
Adv Ther 2022 Apr;39(4):1502-1523. Epub 2022 Feb 27 doi: 10.1007/s12325-022-02074-9. PMID: 35224702Free PMC Article
Daugėlaitė G, Užkuraitytė K, Jagelavičienė E, Filipauskas A
Medicina (Kaunas) 2019 Jan 22;55(2) doi: 10.3390/medicina55020025. PMID: 30678228Free PMC Article
Zecha JA, Raber-Durlacher JE, Nair RG, Epstein JB, Sonis ST, Elad S, Hamblin MR, Barasch A, Migliorati CA, Milstein DM, Genot MT, Lansaat L, van der Brink R, Arnabat-Dominguez J, van der Molen L, Jacobi I, van Diessen J, de Lange J, Smeele LE, Schubert MM, Bensadoun RJ
Support Care Cancer 2016 Jun;24(6):2781-92. Epub 2016 Mar 16 doi: 10.1007/s00520-016-3152-z. PMID: 26984240Free PMC Article

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