U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Spinal cord ischemia

MedGen UID:
155706
Concept ID:
C0752130
Disease or Syndrome
Synonyms: Cord Ischemia, Spinal; Cord Ischemias, Spinal; Ischemia, Spinal Cord; Ischemias, Spinal Cord; Ischemic Myelopathies; Ischemic Myelopathy; Myelopathies, Ischemic; Myelopathy, Ischemic; Spinal Cord Ischemia; Spinal Cord Ischemias
SNOMED CT: Ischemic disorder of spinal cord (371029002); Ischemia of spinal cord (371029002); Spinal cord ischemia (371029002)
 
Monarch Initiative: MONDO:0020688

Definition

Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with arteriosclerosis, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to infarction of spinal cord tissue. [from MONDO]

Term Hierarchy

Professional guidelines

PubMed

Motyl CM, Beck AW
Semin Vasc Surg 2022 Sep;35(3):297-305. Epub 2022 Jul 3 doi: 10.1053/j.semvascsurg.2022.06.005. PMID: 36153070
Nardone R, Pikija S, Mutzenbach JS, Seidl M, Leis S, Trinka E, Sellner J
Drug Discov Today 2016 Oct;21(10):1632-1641. Epub 2016 Jun 17 doi: 10.1016/j.drudis.2016.06.015. PMID: 27326910
Farooqui AA, Ong WY, Horrocks LA
Pharmacol Rev 2006 Sep;58(3):591-620. doi: 10.1124/pr.58.3.7. PMID: 16968951

Recent clinical studies

Etiology

Behzadi F, Simon JE, Zielke TJ, Cook JT, Costa RA, Bechara CF, Prabhu VC
Ann Vasc Surg 2023 Apr;91:36-49. Epub 2023 Jan 2 doi: 10.1016/j.avsg.2022.12.079. PMID: 36603707
Douglas AG, Xu DJ, Shah MP
Neurol Clin 2022 Feb;40(1):133-156. doi: 10.1016/j.ncl.2021.08.009. PMID: 34798966
Hsu JL, Cheng MY, Liao MF, Hsu HC, Weng YC, Chang KH, Chang HS, Kuo HC, Huang CC, Lyu RK, Lin KJ, Ro LS
Sci Rep 2019 May 15;9(1):7435. doi: 10.1038/s41598-019-43606-8. PMID: 31092838Free PMC Article
Yadav N, Pendharkar H, Kulkarni GB
J Stroke Cerebrovasc Dis 2018 Oct;27(10):2810-2821. Epub 2018 Aug 6 doi: 10.1016/j.jstrokecerebrovasdis.2018.06.008. PMID: 30093205
Schraag S
Best Pract Res Clin Anaesthesiol 2016 Sep;30(3):381-93. Epub 2016 Jun 9 doi: 10.1016/j.bpa.2016.06.001. PMID: 27650347

Diagnosis

Behzadi F, Simon JE, Zielke TJ, Cook JT, Costa RA, Bechara CF, Prabhu VC
Ann Vasc Surg 2023 Apr;91:36-49. Epub 2023 Jan 2 doi: 10.1016/j.avsg.2022.12.079. PMID: 36603707
Douglas AG, Xu DJ, Shah MP
Neurol Clin 2022 Feb;40(1):133-156. doi: 10.1016/j.ncl.2021.08.009. PMID: 34798966
Omran S, Raude B, Schawe L, Carstens JC, Angermair S, Berger C, Konietschke F, Treskatsch S, Greiner A
Ann Vasc Surg 2022 Apr;81:138-147. Epub 2021 Nov 12 doi: 10.1016/j.avsg.2021.09.042. PMID: 34780950
Pini R, Faggioli G, Paraskevas KI, Alaidroos M, Palermo S, Gallitto E, Gargiulo M
J Vasc Surg 2022 Apr;75(4):1466-1477.e8. Epub 2021 Nov 1 doi: 10.1016/j.jvs.2021.10.015. PMID: 34736999
Yadav N, Pendharkar H, Kulkarni GB
J Stroke Cerebrovasc Dis 2018 Oct;27(10):2810-2821. Epub 2018 Aug 6 doi: 10.1016/j.jstrokecerebrovasdis.2018.06.008. PMID: 30093205

Therapy

Behzadi F, Simon JE, Zielke TJ, Cook JT, Costa RA, Bechara CF, Prabhu VC
Ann Vasc Surg 2023 Apr;91:36-49. Epub 2023 Jan 2 doi: 10.1016/j.avsg.2022.12.079. PMID: 36603707
Pini R, Faggioli G, Paraskevas KI, Alaidroos M, Palermo S, Gallitto E, Gargiulo M
J Vasc Surg 2022 Apr;75(4):1466-1477.e8. Epub 2021 Nov 1 doi: 10.1016/j.jvs.2021.10.015. PMID: 34736999
Barak U, Sheinis D, Sidon E, Shemesh S, Amitai A, Ohana N
Isr Med Assoc J 2021 Aug;23(8):521-525. PMID: 34392627
DeSart K, Scali ST, Feezor RJ, Hong M, Hess PJ Jr, Beaver TM, Huber TS, Beck AW
J Vasc Surg 2013 Sep;58(3):635-42.e2. Epub 2013 Apr 13 doi: 10.1016/j.jvs.2013.02.036. PMID: 23591190Free PMC Article
Mockford KA, Girn HR, Homer-Vanniasinkam S
Eur J Vasc Endovasc Surg 2009 Apr;37(4):437-42. Epub 2009 Feb 13 doi: 10.1016/j.ejvs.2008.12.017. PMID: 19217807

Prognosis

Behzadi F, Simon JE, Zielke TJ, Cook JT, Costa RA, Bechara CF, Prabhu VC
Ann Vasc Surg 2023 Apr;91:36-49. Epub 2023 Jan 2 doi: 10.1016/j.avsg.2022.12.079. PMID: 36603707
Wu J, Fu YS, Lin K, Huang X, Chen YJ, Lai D, Kang N, Huang L, Weng CF
Biomed Pharmacother 2022 Sep;153:113339. Epub 2022 Jun 30 doi: 10.1016/j.biopha.2022.113339. PMID: 35780614
Yadav N, Pendharkar H, Kulkarni GB
J Stroke Cerebrovasc Dis 2018 Oct;27(10):2810-2821. Epub 2018 Aug 6 doi: 10.1016/j.jstrokecerebrovasdis.2018.06.008. PMID: 30093205
Schraag S
Best Pract Res Clin Anaesthesiol 2016 Sep;30(3):381-93. Epub 2016 Jun 9 doi: 10.1016/j.bpa.2016.06.001. PMID: 27650347
Wiggins GC, Shaffrey CI, Abel MF, Menezes AH
Neurosurg Focus 2003 Jan 15;14(1):e3. doi: 10.3171/foc.2003.14.1.4. PMID: 15766220

Clinical prediction guides

Behzadi F, Simon JE, Zielke TJ, Cook JT, Costa RA, Bechara CF, Prabhu VC
Ann Vasc Surg 2023 Apr;91:36-49. Epub 2023 Jan 2 doi: 10.1016/j.avsg.2022.12.079. PMID: 36603707
Wu J, Fu YS, Lin K, Huang X, Chen YJ, Lai D, Kang N, Huang L, Weng CF
Biomed Pharmacother 2022 Sep;153:113339. Epub 2022 Jun 30 doi: 10.1016/j.biopha.2022.113339. PMID: 35780614
Hsu JL, Cheng MY, Liao MF, Hsu HC, Weng YC, Chang KH, Chang HS, Kuo HC, Huang CC, Lyu RK, Lin KJ, Ro LS
Ann Clin Transl Neurol 2019 Aug;6(8):1456-1464. Epub 2019 Jul 15 doi: 10.1002/acn3.50840. PMID: 31402616Free PMC Article
Liu J, Li Z, Feng J, Zhou J, Zhao Z, Bao X, Zhao Y, Xu Z, Wu J, Wang H, Feng R, Jing Z
J Endovasc Ther 2019 Oct;26(5):668-675. Epub 2019 Jul 31 doi: 10.1177/1526602819863779. PMID: 31364463
Yadav N, Pendharkar H, Kulkarni GB
J Stroke Cerebrovasc Dis 2018 Oct;27(10):2810-2821. Epub 2018 Aug 6 doi: 10.1016/j.jstrokecerebrovasdis.2018.06.008. PMID: 30093205

Recent systematic reviews

Leone N, D'Oria M, Mani K, Oderich G, Maleti G, Bartolotti LAM, Silingardi R, Lepidi S, Gennai S
J Vasc Surg 2024 Aug;80(2):586-594.e5. Epub 2024 Apr 16 doi: 10.1016/j.jvs.2024.04.038. PMID: 38636609
Nana P, Spanos K, Brotis A, Fabre D, Mastracci T, Haulon S
Eur J Vasc Endovasc Surg 2023 Apr;65(4):503-512. Epub 2023 Jan 16 doi: 10.1016/j.ejvs.2023.01.008. PMID: 36657704
Li HL, Chan YC, Jia HY, Cheng SW
Ann Vasc Surg 2022 Sep;85:371-382. Epub 2022 Mar 24 doi: 10.1016/j.avsg.2022.03.020. PMID: 35339592
Pini R, Faggioli G, Paraskevas KI, Alaidroos M, Palermo S, Gallitto E, Gargiulo M
J Vasc Surg 2022 Apr;75(4):1466-1477.e8. Epub 2021 Nov 1 doi: 10.1016/j.jvs.2021.10.015. PMID: 34736999
Spanos K, Tsilimparis N, Rohlffs F, Wipper S, Detter C, Behrendt CA, Debus SE, Kölbel T
J Cardiovasc Surg (Torino) 2018 Aug;59(4):559-571. Epub 2018 Jan 19 doi: 10.23736/S0021-9509.18.10412-5. PMID: 29355297

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...