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Primary Brain Stem Neoplasm

MedGen UID:
155948
Concept ID:
C0751886
Neoplastic Process
Synonyms: Brain Stem Neoplasms, Primary; Brainstem Neoplasm, Primary; Brainstem Neoplasms, Primary; Neoplasm, Primary Brainstem; Neoplasms, Brainstem, Primary; Neoplasms, Primary Brainstem; Primary Brain Stem Neoplasms; Primary Brainstem Neoplasm; Primary Brainstem Neoplasms

Definition

A neoplasm that originates from the brain stem. [from NCI]

Professional guidelines

PubMed

Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012Free PMC Article
Biermann J, Melms JC, Amin AD, Wang Y, Caprio LA, Karz A, Tagore S, Barrera I, Ibarra-Arellano MA, Andreatta M, Fullerton BT, Gretarsson KH, Sahu V, Mangipudy VS, Nguyen TTT, Nair A, Rogava M, Ho P, Koch PD, Banu M, Humala N, Mahajan A, Walsh ZH, Shah SB, Vaccaro DH, Caldwell B, Mu M, Wünnemann F, Chazotte M, Berhe S, Luoma AM, Driver J, Ingham M, Khan SA, Rapisuwon S, Slingluff CL Jr, Eigentler T, Röcken M, Carvajal R, Atkins MB, Davies MA, Agustinus A, Bakhoum SF, Azizi E, Siegelin M, Lu C, Carmona SJ, Hibshoosh H, Ribas A, Canoll P, Bruce JN, Bi WL, Agrawal P, Schapiro D, Hernando E, Macosko EZ, Chen F, Schwartz GK, Izar B
Cell 2022 Jul 7;185(14):2591-2608.e30. doi: 10.1016/j.cell.2022.06.007. PMID: 35803246Free PMC Article
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article

Recent clinical studies

Etiology

Ni S, Chen R, Hu K
Drug Discov Today 2022 May;27(5):1218-1235. Epub 2021 Dec 23 doi: 10.1016/j.drudis.2021.12.016. PMID: 34954326
Eisele SC, Reardon DA
Cancer 2016 Sep 15;122(18):2799-809. Epub 2016 Jun 21 doi: 10.1002/cncr.29920. PMID: 27327773
Ramos A, Hilario A, Lagares A, Salvador E, Perez-Nuñez A, Sepulveda J
Semin Ultrasound CT MR 2013 Apr;34(2):104-12. doi: 10.1053/j.sult.2013.01.001. PMID: 23522775
Grimm SA, Chamberlain MC
Curr Neurol Neurosci Rep 2013 May;13(5):346. doi: 10.1007/s11910-013-0346-3. PMID: 23512689
Reyes-Botero G, Mokhtari K, Martin-Duverneuil N, Delattre JY, Laigle-Donadey F
Oncologist 2012;17(3):388-97. Epub 2012 Mar 1 doi: 10.1634/theoncologist.2011-0335. PMID: 22382458Free PMC Article

Diagnosis

Lyu Y, Guo Y, Okeoma CM, Yan Z, Hu N, Li Z, Zhou S, Zhao X, Li J, Wang X
Biomed Pharmacother 2023 Jul;163:114630. Epub 2023 Apr 23 doi: 10.1016/j.biopha.2023.114630. PMID: 37094548
Bernstock JD, Hoffman SE, Kappel AD, Valdes PA, Essayed W, Klinger NV, Kang KD, Totsch SK, Olsen HE, Schlappi CW, Filipski K, Gessler FA, Baird L, Filbin MG, Hashizume R, Becher OJ, Friedman GK
Oncoimmunology 2022;11(1):2124058. Epub 2022 Sep 26 doi: 10.1080/2162402X.2022.2124058. PMID: 36185807Free PMC Article
Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, Patiño-García A, Dobbs J, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, Puigdelloses M, Laspidea V, Astigarraga I, Lopez-Ibor B, Cruz O, Oscoz Lizarbe M, Hervas-Stubbs S, Alkorta-Aranburu G, Tamayo I, Tavira B, Hernandez-Alcoceba R, Jones C, Dharmadhikari G, Ruiz-Moreno C, Stunnenberg H, Hulleman E, van der Lugt J, Idoate MÁ, Diez-Valle R, Esparragosa Vázquez I, Villalba M, de Andrea C, Núñez-Córdoba JM, Ewald B, Robbins J, Fueyo J, Gomez-Manzano C, Lang FF, Tejada S, Alonso MM
N Engl J Med 2022 Jun 30;386(26):2471-2481. doi: 10.1056/NEJMoa2202028. PMID: 35767439
Grimm SA, Chamberlain MC
Curr Neurol Neurosci Rep 2013 May;13(5):346. doi: 10.1007/s11910-013-0346-3. PMID: 23512689
Reyes-Botero G, Mokhtari K, Martin-Duverneuil N, Delattre JY, Laigle-Donadey F
Oncologist 2012;17(3):388-97. Epub 2012 Mar 1 doi: 10.1634/theoncologist.2011-0335. PMID: 22382458Free PMC Article

Therapy

Shan S, Chen J, Sun Y, Wang Y, Xia B, Tan H, Pan C, Gu G, Zhong J, Qing G, Zhang Y, Wang J, Wang Y, Wang Y, Zuo P, Xu C, Li F, Guo W, Xu L, Chen M, Fan Y, Zhang L, Liang XJ
Adv Sci (Weinh) 2022 Jul;9(21):e2200353. Epub 2022 May 18 doi: 10.1002/advs.202200353. PMID: 35585670Free PMC Article
Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M
Nature 2022 Mar;603(7903):934-941. Epub 2022 Feb 7 doi: 10.1038/s41586-022-04489-4. PMID: 35130560Free PMC Article
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article
Perrone MG, Ruggiero A, Centonze A, Carrieri A, Ferorelli S, Scilimati A
Curr Med Chem 2021;28(17):3287-3317. doi: 10.2174/0929867327666200806110206. PMID: 32767913
Weller M, Le Rhun E
Cancer Treat Rev 2020 Jul;87:102029. Epub 2020 May 4 doi: 10.1016/j.ctrv.2020.102029. PMID: 32408220

Prognosis

Tosi U, Souweidane M
Childs Nerv Syst 2023 Oct;39(10):2675-2686. Epub 2023 Jun 29 doi: 10.1007/s00381-023-06037-5. PMID: 37382660
Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, Patiño-García A, Dobbs J, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, Puigdelloses M, Laspidea V, Astigarraga I, Lopez-Ibor B, Cruz O, Oscoz Lizarbe M, Hervas-Stubbs S, Alkorta-Aranburu G, Tamayo I, Tavira B, Hernandez-Alcoceba R, Jones C, Dharmadhikari G, Ruiz-Moreno C, Stunnenberg H, Hulleman E, van der Lugt J, Idoate MÁ, Diez-Valle R, Esparragosa Vázquez I, Villalba M, de Andrea C, Núñez-Córdoba JM, Ewald B, Robbins J, Fueyo J, Gomez-Manzano C, Lang FF, Tejada S, Alonso MM
N Engl J Med 2022 Jun 30;386(26):2471-2481. doi: 10.1056/NEJMoa2202028. PMID: 35767439
Perrone MG, Ruggiero A, Centonze A, Carrieri A, Ferorelli S, Scilimati A
Curr Med Chem 2021;28(17):3287-3317. doi: 10.2174/0929867327666200806110206. PMID: 32767913
Eisele SC, Reardon DA
Cancer 2016 Sep 15;122(18):2799-809. Epub 2016 Jun 21 doi: 10.1002/cncr.29920. PMID: 27327773
Jallo GI, Biser-Rohrbaugh A, Freed D
Childs Nerv Syst 2004 Mar;20(3):143-53. Epub 2003 Dec 11 doi: 10.1007/s00381-003-0870-6. PMID: 14669023

Clinical prediction guides

Sun Z, Zhao Y, Wei Y, Ding X, Tan C, Wang C
Front Immunol 2022;13:939523. Epub 2022 Aug 25 doi: 10.3389/fimmu.2022.939523. PMID: 36091049Free PMC Article
Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M
Nature 2022 Mar;603(7903):934-941. Epub 2022 Feb 7 doi: 10.1038/s41586-022-04489-4. PMID: 35130560Free PMC Article
Butler M, Pongor L, Su YT, Xi L, Raffeld M, Quezado M, Trepel J, Aldape K, Pommier Y, Wu J
Trends Cancer 2020 May;6(5):380-391. Epub 2020 Mar 27 doi: 10.1016/j.trecan.2020.02.010. PMID: 32348734Free PMC Article
Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y
Cancer Cell 2019 Nov 11;36(5):528-544.e10. Epub 2019 Oct 17 doi: 10.1016/j.ccell.2019.09.005. PMID: 31631026
Campos B, Olsen LR, Urup T, Poulsen HS
Oncogene 2016 Nov 10;35(45):5819-5825. Epub 2016 Apr 4 doi: 10.1038/onc.2016.85. PMID: 27041580

Recent systematic reviews

Ius T, Lombardi G, Baiano C, Berardinelli J, Romano A, Montemurro N, Cavallo LM, Pasqualetti F, Feletti A
Curr Oncol 2023 Nov 7;30(11):9772-9785. doi: 10.3390/curroncol30110709. PMID: 37999129Free PMC Article
Najafi M, Jahanbakhshi A, Gomar M, Iotti C, Giaccherini L, Rezaie O, Cavallieri F, Deantonio L, Bardoscia L, Botti A, Sardaro A, Cozzi S, Ciammella P
Curr Oncol 2022 Apr 22;29(5):2995-3012. doi: 10.3390/curroncol29050244. PMID: 35621634Free PMC Article
Wang KW, Fleming A, Johnston DL, Zelcer SM, Rassekh SR, Ladhani S, Socha A, Shinuda J, Jaber S, Burrow S, Singh SK, Banfield L, de Souza RJ, Thabane L, Samaan MC
Clin Obes 2018 Feb;8(1):55-67. Epub 2017 Oct 11 doi: 10.1111/cob.12224. PMID: 29024558
Ailion AS, Hortman K, King TZ
Neuropsychol Rev 2017 Sep;27(3):220-244. Epub 2017 Jun 23 doi: 10.1007/s11065-017-9352-6. PMID: 28646252
Kerbauy MN, Moraes FY, Lok BH, Ma J, Kerbauy LN, Spratt DE, Santos FP, Perini GF, Berlin A, Chung C, Hamerschlak N, Yahalom J
Radiother Oncol 2017 Mar;122(3):352-361. Epub 2017 Jan 16 doi: 10.1016/j.radonc.2016.12.033. PMID: 28104300

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