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Intracranial Hemorrhage, Hypertensive

MedGen UID:
155952
•Concept ID:
C0751891
•
Pathologic Function
Synonyms: Hemorrhage, Hypertensive Intracranial; Hemorrhage, Intracranial Hypertensive; Hemorrhages, Hypertensive Intracranial; Hemorrhages, Intracranial Hypertensive; Hypertensive Hemorrhage, Intracranial; Hypertensive Hemorrhages, Intracranial; Hypertensive Intracranial Hemorrhage; Hypertensive Intracranial Hemorrhages; Intracranial Hemorrhages, Hypertensive; Intracranial Hypertensive Hemorrhage; Intracranial Hypertensive Hemorrhages

Definition

Bleeding within the SKULL that is caused by systemic HYPERTENSION, usually in association with INTRACRANIAL ARTERIOSCLEROSIS. Hypertensive hemorrhages are most frequent in the BASAL GANGLIA; CEREBELLUM; PONS; and THALAMUS; but may also involve the CEREBRAL CORTEX, subcortical white matter, and other brain structures. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial Hemorrhage, Hypertensive

Professional guidelines

PubMed

Endoscopic third ventriculostomy in the management of communicating hydrocephalus: a preliminary study.
Hailong F, Guangfu H, Haibin T, Hong P, Yong C, Weidong L, Dongdong Z
J Neurosurg 2008 Nov;109(5):923-30. doi: 10.3171/JNS/2008/109/11/0923. PMID: 18976086

Recent clinical studies

Etiology

Arrival blood pressure in hypertensive and non-hypertensive spontaneous intracerebral hemorrhage.
Reznik ME, Fakhri N, Moody S, Murray K, Costa S, Yaghi S, Schrag M, Madsen TE, Burton TM, Cutting S, Mahta A, Wendell LC, Thompson BB, Rao SS, Stretz C, Furie KL, Mac Grory B
J Neurol Sci 2020 Sep 15;416:117000. Epub 2020 Jun 19 doi: 10.1016/j.jns.2020.117000. PMID: 32593888
Current management of spontaneous intracerebral haemorrhage.
Dastur CK, Yu W
Stroke Vasc Neurol 2017 Mar;2(1):21-29. Epub 2017 Feb 24 doi: 10.1136/svn-2016-000047. PMID: 28959487Free PMC Article
The Case.
Mishra R
Camb Q Healthc Ethics 2016 Apr;25(2):330. doi: 10.1017/S0963180115000626. PMID: 26957457
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H
Lancet 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994Free PMC Article
Impact of hypertension on stroke.
Dubow J, Fink ME
Curr Atheroscler Rep 2011 Aug;13(4):298-305. doi: 10.1007/s11883-011-0187-y. PMID: 21626308

Diagnosis

Arrival blood pressure in hypertensive and non-hypertensive spontaneous intracerebral hemorrhage.
Reznik ME, Fakhri N, Moody S, Murray K, Costa S, Yaghi S, Schrag M, Madsen TE, Burton TM, Cutting S, Mahta A, Wendell LC, Thompson BB, Rao SS, Stretz C, Furie KL, Mac Grory B
J Neurol Sci 2020 Sep 15;416:117000. Epub 2020 Jun 19 doi: 10.1016/j.jns.2020.117000. PMID: 32593888
Development and validation of the hypertensive intracerebral hemorrhage prognosis models.
Ding W, Gu Z, Song D, Liu J, Zheng G, Tu C
Medicine (Baltimore) 2018 Sep;97(39):e12446. doi: 10.1097/MD.0000000000012446. PMID: 30278523Free PMC Article
Therapeutic Approach to Hypertensive Emergencies: Hemorrhagic Stroke.
Salvetti M, Paini A, Bertacchini F, Aggiusti C, Stassaldi D, Verzeri L, Saccà G, Muiesan ML
High Blood Press Cardiovasc Prev 2018 Jun;25(2):191-195. Epub 2018 Jun 4 doi: 10.1007/s40292-018-0262-3. PMID: 29869130
The Case.
Mishra R
Camb Q Healthc Ethics 2016 Apr;25(2):330. doi: 10.1017/S0963180115000626. PMID: 26957457
The diagnosis and management of cerebrovascular disease in diabetes.
Phipps MS, Jastreboff AM, Furie K, Kernan WN
Curr Diab Rep 2012 Jun;12(3):314-23. doi: 10.1007/s11892-012-0271-x. PMID: 22492061

Therapy

Therapeutic Approach to Hypertensive Emergencies: Hemorrhagic Stroke.
Salvetti M, Paini A, Bertacchini F, Aggiusti C, Stassaldi D, Verzeri L, Saccà G, Muiesan ML
High Blood Press Cardiovasc Prev 2018 Jun;25(2):191-195. Epub 2018 Jun 4 doi: 10.1007/s40292-018-0262-3. PMID: 29869130
Current management of spontaneous intracerebral haemorrhage.
Dastur CK, Yu W
Stroke Vasc Neurol 2017 Mar;2(1):21-29. Epub 2017 Feb 24 doi: 10.1136/svn-2016-000047. PMID: 28959487Free PMC Article
Effect of integrated traditional Chinese and Western medicine therapy for acute hypertensive intracerebral hemorrhage: a meta-analysis.
Xu S, Pang Q, Lin Z, Zhang N
Artif Cells Nanomed Biotechnol 2017 Sep;45(6):1-6. Epub 2016 Aug 28 doi: 10.1080/21691401.2016.1215327. PMID: 27570142
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H
Lancet 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994Free PMC Article
Impact of hypertension on stroke.
Dubow J, Fink ME
Curr Atheroscler Rep 2011 Aug;13(4):298-305. doi: 10.1007/s11883-011-0187-y. PMID: 21626308

Prognosis

Prognostic prediction of hypertensive intracerebral hemorrhage using CT radiomics and machine learning.
Xu X, Zhang J, Yang K, Wang Q, Chen X, Xu B
Brain Behav 2021 May;11(5):e02085. Epub 2021 Feb 24 doi: 10.1002/brb3.2085. PMID: 33624945Free PMC Article
Development and validation of the hypertensive intracerebral hemorrhage prognosis models.
Ding W, Gu Z, Song D, Liu J, Zheng G, Tu C
Medicine (Baltimore) 2018 Sep;97(39):e12446. doi: 10.1097/MD.0000000000012446. PMID: 30278523Free PMC Article
Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis.
Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X
BMC Neurol 2018 Sep 3;18(1):136. doi: 10.1186/s12883-018-1138-9. PMID: 30176811Free PMC Article
Differences Between Vascular Structural Abnormality and Hypertensive Intracerebral Hemorrhage.
Lei C, Wu B, Liu M, Cao T, Wang Q, Dong W
J Stroke Cerebrovasc Dis 2015 Aug;24(8):1811-6. Epub 2015 Jun 13 doi: 10.1016/j.jstrokecerebrovasdis.2015.04.006. PMID: 26077131
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H
Lancet 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994Free PMC Article

Clinical prediction guides

Prognostic prediction of hypertensive intracerebral hemorrhage using CT radiomics and machine learning.
Xu X, Zhang J, Yang K, Wang Q, Chen X, Xu B
Brain Behav 2021 May;11(5):e02085. Epub 2021 Feb 24 doi: 10.1002/brb3.2085. PMID: 33624945Free PMC Article
Predicting Recurrent Hypertensive Intracerebral Hemorrhage: Derivation and Validation of a Risk-Scoring Model Based on Clinical Characteristics.
Zhang S, Zhang X, Ling Y, Li A
World Neurosurg 2019 Jul;127:e162-e171. Epub 2019 Mar 12 doi: 10.1016/j.wneu.2019.03.024. PMID: 30876994
Development and validation of the hypertensive intracerebral hemorrhage prognosis models.
Ding W, Gu Z, Song D, Liu J, Zheng G, Tu C
Medicine (Baltimore) 2018 Sep;97(39):e12446. doi: 10.1097/MD.0000000000012446. PMID: 30278523Free PMC Article
Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis.
Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X
BMC Neurol 2018 Sep 3;18(1):136. doi: 10.1186/s12883-018-1138-9. PMID: 30176811Free PMC Article
Therapeutic Approach to Hypertensive Emergencies: Hemorrhagic Stroke.
Salvetti M, Paini A, Bertacchini F, Aggiusti C, Stassaldi D, Verzeri L, Saccà G, Muiesan ML
High Blood Press Cardiovasc Prev 2018 Jun;25(2):191-195. Epub 2018 Jun 4 doi: 10.1007/s40292-018-0262-3. PMID: 29869130

Recent systematic reviews

Neuroendoscopic Surgery versus Craniotomy for Supratentorial Hypertensive Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis.
Sun S, Li Y, Zhang H, Gao H, Zhou X, Xu Y, Yan K, Wang X
World Neurosurg 2020 Feb;134:477-488. Epub 2019 Nov 15 doi: 10.1016/j.wneu.2019.10.115. PMID: 31669683
Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis.
Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X
BMC Neurol 2018 Sep 3;18(1):136. doi: 10.1186/s12883-018-1138-9. PMID: 30176811Free PMC Article
Effects of Intensive Blood Pressure Lowering on Intracerebral Hemorrhage Outcomes: A Meta-Analysis of Randomized Controlled Trials.
Ma J, Li H, Liu Y, You C, Huang S, Ma L
Turk Neurosurg 2015;25(4):544-51. doi: 10.5137/1019-5149.JTN.9270-13.0. PMID: 26242330
Intensive blood pressure reduction in acute intracerebral hemorrhage: a meta-analysis.
Tsivgoulis G, Katsanos AH, Butcher KS, Boviatsis E, Triantafyllou N, Rizos I, Alexandrov AV
Neurology 2014 Oct 21;83(17):1523-9. Epub 2014 Sep 19 doi: 10.1212/WNL.0000000000000917. PMID: 25239836
Hypertension and the post-carotid endarterectomy cerebral hyperperfusion syndrome.
Bouri S, Thapar A, Shalhoub J, Jayasooriya G, Fernando A, Franklin IJ, Davies AH
Eur J Vasc Endovasc Surg 2011 Feb;41(2):229-37. Epub 2010 Dec 4 doi: 10.1016/j.ejvs.2010.10.016. PMID: 21131217

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