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Distributive shock

MedGen UID:: 1612211
•Concept ID:: C2938913
•: Disease or Syndrome

HPO:	HP:0031275

Definition

A hyperdynamic process resulting from excessive vasodilatation. Impaired blood flow causes inadequate tissue perfusion, which can lead to end-organ damage [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDistributive shock

Disease
- Disorder by Site
  - Disorder of cardiovascular system
    - Abnormality of the cardiovascular system
      - Abnormal cardiovascular system physiology
        Shock
        Distributive shock

Professional guidelines

PubMed

Volume Management with Kidney Replacement Therapy in the Critically Ill Patient.

Wang CH, Fay K, Shashaty MGS, Negoianu D
Clin J Am Soc Nephrol 2023 Jun 1;18(6):788-802. Epub 2023 Apr 5 doi: 10.2215/CJN.0000000000000164. PMID: 37016472 Free PMC Article

Not all Shock States Are Created Equal: A Review of the Diagnosis and Management of Septic, Hypovolemic, Cardiogenic, Obstructive, and Distributive Shock.

Khorsand S, Helou MF, Satyapriya V, Kopanczyk R, Khanna AK
Anesthesiol Clin 2023 Mar;41(1):1-25. doi: 10.1016/j.anclin.2022.11.002. PMID: 36871993

The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.

Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765 Free PMC Article

See all (21)

Recent clinical studies

Etiology

Resuscitation fluids.

Casey JD, Brown RM, Semler MW
Curr Opin Crit Care 2018 Dec;24(6):512-518. doi: 10.1097/MCC.0000000000000551. PMID: 30247219 Free PMC Article

Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis.

McIntyre WF, Um KJ, Alhazzani W, Lengyel AP, Hajjar L, Gordon AC, Lamontagne F, Healey JS, Whitlock RP, Belley-Côté EP
JAMA 2018 May 8;319(18):1889-1900. doi: 10.1001/jama.2018.4528. PMID: 29801010 Free PMC Article

Fluid therapy and shock: an integrative literature review.

Silva J, Gonçalves L, Sousa PP
Br J Nurs 2018 Apr 26;27(8):449-454. doi: 10.12968/bjon.2018.27.8.449. PMID: 29683753

Anaphylaxis.

Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Hypovolemic shock: an overview.

Kelley DM
Crit Care Nurs Q 2005 Jan-Mar;28(1):2-19; quiz 20-1. doi: 10.1097/00002727-200501000-00002. PMID: 15732421

See all (56)

Diagnosis

Not all Shock States Are Created Equal: A Review of the Diagnosis and Management of Septic, Hypovolemic, Cardiogenic, Obstructive, and Distributive Shock.

Khorsand S, Helou MF, Satyapriya V, Kopanczyk R, Khanna AK
Anesthesiol Clin 2023 Mar;41(1):1-25. doi: 10.1016/j.anclin.2022.11.002. PMID: 36871993

The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.

Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765 Free PMC Article

The Nomenclature, Definition and Distinction of Types of Shock.

Standl T, Annecke T, Cascorbi I, Heller AR, Sabashnikov A, Teske W
Dtsch Arztebl Int 2018 Nov 9;115(45):757-768. doi: 10.3238/arztebl.2018.0757. PMID: 30573009 Free PMC Article

Anaphylaxis.

Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Hypovolemic shock: an overview.

Kelley DM
Crit Care Nurs Q 2005 Jan-Mar;28(1):2-19; quiz 20-1. doi: 10.1097/00002727-200501000-00002. PMID: 15732421

See all (69)

Therapy

The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.

Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765 Free PMC Article

The Nomenclature, Definition and Distinction of Types of Shock.

Standl T, Annecke T, Cascorbi I, Heller AR, Sabashnikov A, Teske W
Dtsch Arztebl Int 2018 Nov 9;115(45):757-768. doi: 10.3238/arztebl.2018.0757. PMID: 30573009 Free PMC Article

Resuscitation fluids.

Casey JD, Brown RM, Semler MW
Curr Opin Crit Care 2018 Dec;24(6):512-518. doi: 10.1097/MCC.0000000000000551. PMID: 30247219 Free PMC Article

Fluid therapy and shock: an integrative literature review.

Silva J, Gonçalves L, Sousa PP
Br J Nurs 2018 Apr 26;27(8):449-454. doi: 10.12968/bjon.2018.27.8.449. PMID: 29683753

Anaphylaxis.

Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

See all (95)

Prognosis

Volume Management with Kidney Replacement Therapy in the Critically Ill Patient.

Wang CH, Fay K, Shashaty MGS, Negoianu D
Clin J Am Soc Nephrol 2023 Jun 1;18(6):788-802. Epub 2023 Apr 5 doi: 10.2215/CJN.0000000000000164. PMID: 37016472 Free PMC Article

Shock and Myocardial Injury in Children With Multisystem Inflammatory Syndrome Associated With SARS-CoV-2 Infection: What We Know. Case Series and Review of the Literature.

Caro-Patón GL, de Azagra-Garde AM, García-Salido A, Cabrero-Hernández M, Tamariz A, Nieto-Moro M
J Intensive Care Med 2021 Apr;36(4):392-403. Epub 2020 Nov 5 doi: 10.1177/0885066620969350. PMID: 33148089

Angiotensin II (Giapreza): A Distinct Mechanism for the Treatment of Vasodilatory Shock.

Khalique SC, Ferguson N
Cardiol Rev 2019 May/Jun;27(3):167-169. doi: 10.1097/CRD.0000000000000247. PMID: 30601161

Sepsis and the heart.

Hunter JD, Doddi M
Br J Anaesth 2010 Jan;104(1):3-11. doi: 10.1093/bja/aep339. PMID: 19939836

Hypovolemic shock: an overview.

Kelley DM
Crit Care Nurs Q 2005 Jan-Mar;28(1):2-19; quiz 20-1. doi: 10.1097/00002727-200501000-00002. PMID: 15732421

See all (39)

Clinical prediction guides

Angiotensin II and Vasopressin for Vasodilatory Shock: A Critical Appraisal of Catecholamine-Sparing Strategies.

Heavner MS, McCurdy MT, Mazzeffi MA, Galvagno SM Jr, Tanaka KA, Chow JH
J Intensive Care Med 2021 Jun;36(6):635-645. Epub 2020 Mar 30 doi: 10.1177/0885066620911601. PMID: 32223515

Anaphylaxis.

Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Sepsis and the heart.

Hunter JD, Doddi M
Br J Anaesth 2010 Jan;104(1):3-11. doi: 10.1093/bja/aep339. PMID: 19939836

The pathophysiology of shock in anaphylaxis.

Brown SG
Immunol Allergy Clin North Am 2007 May;27(2):165-75, v. doi: 10.1016/j.iac.2007.03.003. PMID: 17493496

Bugged.

Ayling J
Emerg Med Serv 2003 May;32(5):48. PMID: 12776412

See all (41)

Recent systematic reviews

Diagnostic accuracy of point-of-care ultrasound for shock: a systematic review and meta-analysis.

Yoshida T, Yoshida T, Noma H, Nomura T, Suzuki A, Mihara T
Crit Care 2023 May 25;27(1):200. doi: 10.1186/s13054-023-04495-6. PMID: 37231510 Free PMC Article

Does the Addition of Vasopressin to Catecholamine Vasopressors Affect Outcomes in Patients With Distributive Shock?

Roumpf SK, Hunter BR
Ann Emerg Med 2019 Jul;74(1):153-155. Epub 2018 Nov 13 doi: 10.1016/j.annemergmed.2018.10.001. PMID: 30446352

Renal Outcomes of Vasopressin and Its Analogs in Distributive Shock: A Systematic Review and Meta-Analysis of Randomized Trials.

Nedel WL, Rech TH, Ribeiro RA, Pellegrini JAS, Moraes RB
Crit Care Med 2019 Jan;47(1):e44-e51. doi: 10.1097/CCM.0000000000003471. PMID: 30303842

Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis.

Fluid therapy and shock: an integrative literature review.

Silva J, Gonçalves L, Sousa PP
Br J Nurs 2018 Apr 26;27(8):449-454. doi: 10.12968/bjon.2018.27.8.449. PMID: 29683753

See all (8)