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Distributive shock

MedGen UID:
1612211
•Concept ID:
C2938913
•
Disease or Syndrome
HPO: HP:0031275

Definition

A hyperdynamic process resulting from excessive vasodilatation. Impaired blood flow causes inadequate tissue perfusion, which can lead to end-organ damage [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDistributive shock

Professional guidelines

PubMed

Not all Shock States Are Created Equal: A Review of the Diagnosis and Management of Septic, Hypovolemic, Cardiogenic, Obstructive, and Distributive Shock.
Khorsand S, Helou MF, Satyapriya V, Kopanczyk R, Khanna AK
Anesthesiol Clin 2023 Mar;41(1):1-25. doi: 10.1016/j.anclin.2022.11.002. PMID: 36871993
The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.
Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765Free PMC Article
Inclusion of adrenal crisis in the differential diagnosis of distributive shock.
Tompkins MG, Bissell BD, Sowders V, Kern PA
Am J Health Syst Pharm 2020 Mar 5;77(6):415-417. doi: 10.1093/ajhp/zxz324. PMID: 31950137

Recent clinical studies

Etiology

THE EFFICACY AND SAFETY OF VASOPRESSORS FOR SEPTIC SHOCK PATIENTS: A SYSTEMIC REVIEW AND NETWORK META-ANALYSIS.
Jia L, Wang P, Li C, Xie J
Shock 2023 Dec 1;60(6):746-752. Epub 2023 Aug 4 doi: 10.1097/SHK.0000000000002193. PMID: 37548686
Utilization and extravasation of peripheral norepinephrine in the emergency department.
Nguyen TT, Surrey A, Barmaan B, Miller S, Oswalt A, Evans D, Dhindsa H
Am J Emerg Med 2021 Jan;39:55-59. Epub 2020 Jan 8 doi: 10.1016/j.ajem.2020.01.014. PMID: 31959524
Resuscitation fluids.
Casey JD, Brown RM, Semler MW
Curr Opin Crit Care 2018 Dec;24(6):512-518. doi: 10.1097/MCC.0000000000000551. PMID: 30247219Free PMC Article
Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis.
McIntyre WF, Um KJ, Alhazzani W, Lengyel AP, Hajjar L, Gordon AC, Lamontagne F, Healey JS, Whitlock RP, Belley-Côté EP
JAMA 2018 May 8;319(18):1889-1900. doi: 10.1001/jama.2018.4528. PMID: 29801010Free PMC Article
Anaphylaxis.
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Diagnosis

Diagnostic accuracy of point-of-care ultrasound for shock: a systematic review and meta-analysis.
Yoshida T, Yoshida T, Noma H, Nomura T, Suzuki A, Mihara T
Crit Care 2023 May 25;27(1):200. doi: 10.1186/s13054-023-04495-6. PMID: 37231510Free PMC Article
Not all Shock States Are Created Equal: A Review of the Diagnosis and Management of Septic, Hypovolemic, Cardiogenic, Obstructive, and Distributive Shock.
Khorsand S, Helou MF, Satyapriya V, Kopanczyk R, Khanna AK
Anesthesiol Clin 2023 Mar;41(1):1-25. doi: 10.1016/j.anclin.2022.11.002. PMID: 36871993
The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.
Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765Free PMC Article
The Nomenclature, Definition and Distinction of Types of Shock.
Standl T, Annecke T, Cascorbi I, Heller AR, Sabashnikov A, Teske W
Dtsch Arztebl Int 2018 Nov 9;115(45):757-768. doi: 10.3238/arztebl.2018.0757. PMID: 30573009Free PMC Article
Anaphylaxis.
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890

Therapy

A Clinical Review of Vasopressors in Emergency Medicine.
Stampfl M, DeBlieux P
J Emerg Med 2024 Jul;67(1):e31-e41. Epub 2024 Mar 12 doi: 10.1016/j.jemermed.2024.03.004. PMID: 38789351
THE EFFICACY AND SAFETY OF VASOPRESSORS FOR SEPTIC SHOCK PATIENTS: A SYSTEMIC REVIEW AND NETWORK META-ANALYSIS.
Jia L, Wang P, Li C, Xie J
Shock 2023 Dec 1;60(6):746-752. Epub 2023 Aug 4 doi: 10.1097/SHK.0000000000002193. PMID: 37548686
The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring.
Kashani K, Omer T, Shaw AD
Clin J Am Soc Nephrol 2022 May;17(5):706-716. Epub 2022 Apr 4 doi: 10.2215/CJN.14191021. PMID: 35379765Free PMC Article
The Nomenclature, Definition and Distinction of Types of Shock.
Standl T, Annecke T, Cascorbi I, Heller AR, Sabashnikov A, Teske W
Dtsch Arztebl Int 2018 Nov 9;115(45):757-768. doi: 10.3238/arztebl.2018.0757. PMID: 30573009Free PMC Article
Resuscitation fluids.
Casey JD, Brown RM, Semler MW
Curr Opin Crit Care 2018 Dec;24(6):512-518. doi: 10.1097/MCC.0000000000000551. PMID: 30247219Free PMC Article

Prognosis

Utilization and extravasation of peripheral norepinephrine in the emergency department.
Nguyen TT, Surrey A, Barmaan B, Miller S, Oswalt A, Evans D, Dhindsa H
Am J Emerg Med 2021 Jan;39:55-59. Epub 2020 Jan 8 doi: 10.1016/j.ajem.2020.01.014. PMID: 31959524
Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. A Clinical Trial.
Bellomo R, Forni LG, Busse LW, McCurdy MT, Ham KR, Boldt DW, Hästbacka J, Khanna AK, Albertson TE, Tumlin J, Storey K, Handisides D, Tidmarsh GF, Chawla LS, Ostermann M
Am J Respir Crit Care Med 2020 Nov 1;202(9):1253-1261. doi: 10.1164/rccm.201911-2172OC. PMID: 32609011Free PMC Article
Sepsis and the heart.
Hunter JD, Doddi M
Br J Anaesth 2010 Jan;104(1):3-11. doi: 10.1093/bja/aep339. PMID: 19939836
Severe adverse drug reaction to gadobenate dimeglumine.
Singer BD, Woodrick RS, Pedicano JB
ScientificWorldJournal 2009 May 22;9:363-5. doi: 10.1100/tsw.2009.41. PMID: 19468658Free PMC Article
Hypovolemic shock: an overview.
Kelley DM
Crit Care Nurs Q 2005 Jan-Mar;28(1):2-19; quiz 20-1. doi: 10.1097/00002727-200501000-00002. PMID: 15732421

Clinical prediction guides

Utilization and extravasation of peripheral norepinephrine in the emergency department.
Nguyen TT, Surrey A, Barmaan B, Miller S, Oswalt A, Evans D, Dhindsa H
Am J Emerg Med 2021 Jan;39:55-59. Epub 2020 Jan 8 doi: 10.1016/j.ajem.2020.01.014. PMID: 31959524
Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. A Clinical Trial.
Bellomo R, Forni LG, Busse LW, McCurdy MT, Ham KR, Boldt DW, Hästbacka J, Khanna AK, Albertson TE, Tumlin J, Storey K, Handisides D, Tidmarsh GF, Chawla LS, Ostermann M
Am J Respir Crit Care Med 2020 Nov 1;202(9):1253-1261. doi: 10.1164/rccm.201911-2172OC. PMID: 32609011Free PMC Article
Anaphylaxis.
Zilberstein J, McCurdy MT, Winters ME
J Emerg Med 2014 Aug;47(2):182-7. Epub 2014 Jun 2 doi: 10.1016/j.jemermed.2014.04.018. PMID: 24881890
Sepsis and the heart.
Hunter JD, Doddi M
Br J Anaesth 2010 Jan;104(1):3-11. doi: 10.1093/bja/aep339. PMID: 19939836
Occurrence of multiphasic anaphylaxis during a transcontinental air flight.
Brady WJ Jr, Bright HL
Am J Emerg Med 1999 Nov;17(7):695-6. doi: 10.1016/s0735-6757(99)90163-8. PMID: 10597093

Recent systematic reviews

ANGIOTENSIN II IN THE TREATMENT OF DISTRIBUTIVE SHOCK: A SYSTEMATIC-REVIEW AND META-ANALYSIS.
Xourgia E, Exadaktylos AK, Chalkias A, Ziaka M
Shock 2024 Aug 1;62(2):155-164. Epub 2024 Jun 12 doi: 10.1097/SHK.0000000000002384. PMID: 38888542
THE EFFICACY AND SAFETY OF VASOPRESSORS FOR SEPTIC SHOCK PATIENTS: A SYSTEMIC REVIEW AND NETWORK META-ANALYSIS.
Jia L, Wang P, Li C, Xie J
Shock 2023 Dec 1;60(6):746-752. Epub 2023 Aug 4 doi: 10.1097/SHK.0000000000002193. PMID: 37548686
Diagnostic accuracy of point-of-care ultrasound for shock: a systematic review and meta-analysis.
Yoshida T, Yoshida T, Noma H, Nomura T, Suzuki A, Mihara T
Crit Care 2023 May 25;27(1):200. doi: 10.1186/s13054-023-04495-6. PMID: 37231510Free PMC Article
Does the Addition of Vasopressin to Catecholamine Vasopressors Affect Outcomes in Patients With Distributive Shock?
Roumpf SK, Hunter BR
Ann Emerg Med 2019 Jul;74(1):153-155. Epub 2018 Nov 13 doi: 10.1016/j.annemergmed.2018.10.001. PMID: 30446352
Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis.
McIntyre WF, Um KJ, Alhazzani W, Lengyel AP, Hajjar L, Gordon AC, Lamontagne F, Healey JS, Whitlock RP, Belley-Côté EP
JAMA 2018 May 8;319(18):1889-1900. doi: 10.1001/jama.2018.4528. PMID: 29801010Free PMC Article

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