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Abnormal negative emotional state

MedGen UID:
1613560
•Concept ID:
C4531100
•
Mental or Behavioral Dysfunction
Synonym: Negative affectivity
 
HPO: HP:0031467

Definition

An aversive emotional state characterized by negative emotional experiences, preoccupations, or internal states that are often related to negative perceptions of the self, the world, or the future. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal negative emotional state

Professional guidelines

PubMed

Patterns of anxiety and distress over 12 months following participation in HPV primary screening.
Marlow LAV, McBride E, Ridout D, Forster AS, Kitchener H, Waller J
Sex Transm Infect 2022 Jun;98(4):255-261. Epub 2021 Aug 3 doi: 10.1136/sextrans-2020-054780. PMID: 34344834Free PMC Article
Healthcare and psychosocial experiences of individuals with craniofacial microsomia: Patient and caregivers perspectives.
Luquetti DV, Brajcich MR, Stock NM, Heike CL, Johns AL
Int J Pediatr Otorhinolaryngol 2018 Apr;107:164-175. Epub 2018 Feb 7 doi: 10.1016/j.ijporl.2018.02.007. PMID: 29501301Free PMC Article
Differential neural reward mechanisms in treatment-responsive and treatment-resistant schizophrenia.
Vanes LD, Mouchlianitis E, Collier T, Averbeck BB, Shergill SS
Psychol Med 2018 Oct;48(14):2418-2427. Epub 2018 Feb 14 doi: 10.1017/S0033291718000041. PMID: 29439750Free PMC Article

Recent clinical studies

Etiology

Associations between abnormal electroencephalogram microstates and childhood emotional abuse in adolescent depression.
Hu J, Zhou D, Zhao L, Ma L, Peng X, He X, Chen R, Chen W, Jiang Z, Kuang L, Wang W
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Nov 28;48(11):1678-1685. doi: 10.11817/j.issn.1672-7347.2023.230220. PMID: 38432858Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
Behavioural and emotional implications of implantable cardioverter-defibrillators in the young and in athletes.
Dechert BE
Cardiol Young 2017 Jan;27(S1):S138-S142. doi: 10.1017/S1047951116002389. PMID: 28084974
Large-Scale Network Dysfunction in Major Depressive Disorder: A Meta-analysis of Resting-State Functional Connectivity.
Kaiser RH, Andrews-Hanna JR, Wager TD, Pizzagalli DA
JAMA Psychiatry 2015 Jun;72(6):603-11. doi: 10.1001/jamapsychiatry.2015.0071. PMID: 25785575Free PMC Article
Effects of vitamin B12 and folate deficiency on brain development in children.
Black MM
Food Nutr Bull 2008 Jun;29(2 Suppl):S126-31. doi: 10.1177/15648265080292S117. PMID: 18709887Free PMC Article

Diagnosis

Progesterone, reproduction, and psychiatric illness.
Standeven LR, McEvoy KO, Osborne LM
Best Pract Res Clin Obstet Gynaecol 2020 Nov;69:108-126. Epub 2020 Jun 18 doi: 10.1016/j.bpobgyn.2020.06.001. PMID: 32723604Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
Effects of Anorexia Nervosa on the Endocrine System.
Baskaran C, Misra M, Klibanski A
Pediatr Endocrinol Rev 2017 Mar;14(3):302-311. doi: 10.17458/per.vol14.2017.BMK.effectsanorexianervosa. PMID: 28508601
Psychosis.
Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article
Affective instability, family history of mood disorders, and neurodevelopmental disturbance.
Berenbaum H, Bredemeier K, Boden MT, Thompson RJ, Milanak M
Personal Disord 2011 Jul;2(3):220-9. doi: 10.1037/a0022317. PMID: 22448768

Therapy

Associations between abnormal electroencephalogram microstates and childhood emotional abuse in adolescent depression.
Hu J, Zhou D, Zhao L, Ma L, Peng X, He X, Chen R, Chen W, Jiang Z, Kuang L, Wang W
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Nov 28;48(11):1678-1685. doi: 10.11817/j.issn.1672-7347.2023.230220. PMID: 38432858Free PMC Article
Behavioural and emotional implications of implantable cardioverter-defibrillators in the young and in athletes.
Dechert BE
Cardiol Young 2017 Jan;27(S1):S138-S142. doi: 10.1017/S1047951116002389. PMID: 28084974
Psychosis.
Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article
Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis.
Ma Y
Mol Psychiatry 2015 Mar;20(3):311-9. Epub 2014 Mar 25 doi: 10.1038/mp.2014.24. PMID: 24662929
Effects of vitamin B12 and folate deficiency on brain development in children.
Black MM
Food Nutr Bull 2008 Jun;29(2 Suppl):S126-31. doi: 10.1177/15648265080292S117. PMID: 18709887Free PMC Article

Prognosis

Association between parity and female mortality: the mediative role of depressive symptoms.
Deng Z, Wei Y, Dai F, Yang D, Tang D, Liu J, Yin T
Hum Reprod 2024 Oct 1;39(10):2341-2352. doi: 10.1093/humrep/deae196. PMID: 39212040
Psychopathy is associated with fear-specific reductions in neural activity during affective perspective-taking.
Deming P, Dargis M, Haas BW, Brook M, Decety J, Harenski C, Kiehl KA, Koenigs M, Kosson DS
Neuroimage 2020 Dec;223:117342. Epub 2020 Sep 6 doi: 10.1016/j.neuroimage.2020.117342. PMID: 32898678Free PMC Article
Reward Processing in Adolescent Depression Across Neuroimaging Modalities.
O'Callaghan G, Stringaris A
Z Kinder Jugendpsychiatr Psychother 2019 Nov;47(6):535-541. Epub 2019 Apr 8 doi: 10.1024/1422-4917/a000663. PMID: 30957688Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
A cognitive model of generalized anxiety disorder.
Wells A
Behav Modif 1999 Oct;23(4):526-55. doi: 10.1177/0145445599234002. PMID: 10533439

Clinical prediction guides

Theory of mind in epilepsy.
Watanabe RGS, Thais MERO, Marmentini EL, Freitas TG, Wolf P, Lin K
Epilepsy Behav 2024 Sep;158:109910. Epub 2024 Jul 2 doi: 10.1016/j.yebeh.2024.109910. PMID: 38959746
Associations between abnormal electroencephalogram microstates and childhood emotional abuse in adolescent depression.
Hu J, Zhou D, Zhao L, Ma L, Peng X, He X, Chen R, Chen W, Jiang Z, Kuang L, Wang W
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Nov 28;48(11):1678-1685. doi: 10.11817/j.issn.1672-7347.2023.230220. PMID: 38432858Free PMC Article
Reward Processing in Adolescent Depression Across Neuroimaging Modalities.
O'Callaghan G, Stringaris A
Z Kinder Jugendpsychiatr Psychother 2019 Nov;47(6):535-541. Epub 2019 Apr 8 doi: 10.1024/1422-4917/a000663. PMID: 30957688Free PMC Article
Cognitive deficits in bipolar disorders: Implications for emotion.
Lima IMM, Peckham AD, Johnson SL
Clin Psychol Rev 2018 Feb;59:126-136. Epub 2017 Nov 21 doi: 10.1016/j.cpr.2017.11.006. PMID: 29195773Free PMC Article
A cognitive model of generalized anxiety disorder.
Wells A
Behav Modif 1999 Oct;23(4):526-55. doi: 10.1177/0145445599234002. PMID: 10533439

Recent systematic reviews

Psychological and Behavioral Impact of Lockdown and Quarantine Measures for COVID-19 Pandemic on Children, Adolescents and Caregivers: A Systematic Review and Meta-Analysis.
Panda PK, Gupta J, Chowdhury SR, Kumar R, Meena AK, Madaan P, Sharawat IK, Gulati S
J Trop Pediatr 2021 Jan 29;67(1) doi: 10.1093/tropej/fmaa122. PMID: 33367907Free PMC Article
The Impact of Communication Surrounding Intrauterine Congenital Anomaly Diagnoses: An Integrative Review.
Berry SN, Colorafi K
J Perinat Neonatal Nurs 2019 Oct/Dec;33(4):301-311. doi: 10.1097/JPN.0000000000000390. PMID: 30741752
'Hot' cognition in major depressive disorder: a systematic review.
Miskowiak KW, Carvalho AF
CNS Neurol Disord Drug Targets 2014;13(10):1787-803. doi: 10.2174/1871527313666141130205713. PMID: 25470389
Mobile phone messaging for communicating results of medical investigations.
Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Car J, Atun R
Cochrane Database Syst Rev 2012 Jun 13;2012(6):CD007456. doi: 10.1002/14651858.CD007456.pub2. PMID: 22696369Free PMC Article

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