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Malignant Neoplasm of Lung - Multiple Primary Sites

MedGen UID:
1613945
Concept ID:
C4528576
Neoplastic Process
Synonyms: MPLC; Multiple Primary Lung Cancers

Definition

Lung cancer comprising malignant neoplasms from two or more sites, as determined by clinicoopathological assessment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Neoplasm of Lung - Multiple Primary Sites

Professional guidelines

PubMed

Iyengar P, All S, Berry MF, Boike TP, Bradfield L, Dingemans AC, Feldman J, Gomez DR, Hesketh PJ, Jabbour SK, Jeter M, Josipovic M, Lievens Y, McDonald F, Perez BA, Ricardi U, Ruffini E, De Ruysscher D, Saeed H, Schneider BJ, Senan S, Widder J, Guckenberger M
Pract Radiat Oncol 2023 Sep-Oct;13(5):393-412. Epub 2023 Apr 25 doi: 10.1016/j.prro.2023.04.004. PMID: 37294262
Patel AN, Simone CB 2nd, Jabbour SK
Ther Adv Respir Dis 2016 Aug;10(4):338-48. Epub 2016 Apr 8 doi: 10.1177/1753465816642636. PMID: 27060187Free PMC Article
Kamaya A, Weinstein S, Desser TS
Semin Ultrasound CT MR 2006 Oct;27(5):389-403. doi: 10.1053/j.sult.2006.06.004. PMID: 17048454

Recent clinical studies

Etiology

Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Ryan C, Stoltzfus KC, Horn S, Chen H, Louie AV, Lehrer EJ, Trifiletti DM, Fox EJ, Abraham JA, Zaorsky NG
Bone 2022 May;158:115783. Epub 2020 Dec 1 doi: 10.1016/j.bone.2020.115783. PMID: 33276151
Cheung DST, Takemura N, Lam TC, Ho JCM, Deng W, Smith R, Yan Y, Lee AWM, Lin CC
Integr Cancer Ther 2021 Jan-Dec;20:15347354211033352. doi: 10.1177/15347354211033352. PMID: 34549648Free PMC Article
Tanoue LT
Clin Chest Med 2020 Jun;41(2):161-174. doi: 10.1016/j.ccm.2020.02.006. PMID: 32402353
Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, Hazell S, Eichler-Jonsson C, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Jabbar F, Spain L, Lall S, Guarch R, Falzon M, Proctor I, Pickering L, Gore M, Watkins TBK, Ward S, Stewart A, DiNatale R, Becerra MF, Reznik E, Hsieh JJ, Richmond TA, Mayhew GF, Hill SM, McNally CD, Jones C, Rosenbaum H, Stanislaw S, Burgess DL, Alexander NR, Swanton C; PEACE; TRACERx Renal Consortium
Cell 2018 Apr 19;173(3):581-594.e12. Epub 2018 Apr 12 doi: 10.1016/j.cell.2018.03.057. PMID: 29656895Free PMC Article

Diagnosis

Lavery JA, Boutros PC, Scott JM, Tammela T, Moskowitz CS, Jones LW
J Clin Oncol 2023 Nov 10;41(32):4982-4992. Epub 2023 Aug 31 doi: 10.1200/JCO.23.00058. PMID: 37651670
Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Ryan C, Stoltzfus KC, Horn S, Chen H, Louie AV, Lehrer EJ, Trifiletti DM, Fox EJ, Abraham JA, Zaorsky NG
Bone 2022 May;158:115783. Epub 2020 Dec 1 doi: 10.1016/j.bone.2020.115783. PMID: 33276151
Cheung DST, Takemura N, Lam TC, Ho JCM, Deng W, Smith R, Yan Y, Lee AWM, Lin CC
Integr Cancer Ther 2021 Jan-Dec;20:15347354211033352. doi: 10.1177/15347354211033352. PMID: 34549648Free PMC Article
Kamaya A, Weinstein S, Desser TS
Semin Ultrasound CT MR 2006 Oct;27(5):389-403. doi: 10.1053/j.sult.2006.06.004. PMID: 17048454

Therapy

Lavery JA, Boutros PC, Scott JM, Tammela T, Moskowitz CS, Jones LW
J Clin Oncol 2023 Nov 10;41(32):4982-4992. Epub 2023 Aug 31 doi: 10.1200/JCO.23.00058. PMID: 37651670
Iyengar P, All S, Berry MF, Boike TP, Bradfield L, Dingemans AC, Feldman J, Gomez DR, Hesketh PJ, Jabbour SK, Jeter M, Josipovic M, Lievens Y, McDonald F, Perez BA, Ricardi U, Ruffini E, De Ruysscher D, Saeed H, Schneider BJ, Senan S, Widder J, Guckenberger M
Pract Radiat Oncol 2023 Sep-Oct;13(5):393-412. Epub 2023 Apr 25 doi: 10.1016/j.prro.2023.04.004. PMID: 37294262
Morales Berstein F, McCartney DL, Lu AT, Tsilidis KK, Bouras E, Haycock P, Burrows K, Phipps AI, Buchanan DD, Cheng I; PRACTICAL consortium, Martin RM, Davey Smith G, Relton CL, Horvath S, Marioni RE, Richardson TG, Richmond RC
Elife 2022 Mar 29;11 doi: 10.7554/eLife.75374. PMID: 35346416Free PMC Article
Cheung DST, Takemura N, Lam TC, Ho JCM, Deng W, Smith R, Yan Y, Lee AWM, Lin CC
Integr Cancer Ther 2021 Jan-Dec;20:15347354211033352. doi: 10.1177/15347354211033352. PMID: 34549648Free PMC Article
Gainor JF, Curigliano G, Kim DW, Lee DH, Besse B, Baik CS, Doebele RC, Cassier PA, Lopes G, Tan DSW, Garralda E, Paz-Ares LG, Cho BC, Gadgeel SM, Thomas M, Liu SV, Taylor MH, Mansfield AS, Zhu VW, Clifford C, Zhang H, Palmer M, Green J, Turner CD, Subbiah V
Lancet Oncol 2021 Jul;22(7):959-969. Epub 2021 Jun 9 doi: 10.1016/S1470-2045(21)00247-3. PMID: 34118197

Prognosis

Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Sudarshan M, Murthy SC
Surg Oncol Clin N Am 2020 Oct;29(4):673-683. Epub 2020 Aug 12 doi: 10.1016/j.soc.2020.06.007. PMID: 32883466
Tanoue LT
Clin Chest Med 2020 Jun;41(2):161-174. doi: 10.1016/j.ccm.2020.02.006. PMID: 32402353
Wang R, Zhu Y, Liu X, Liao X, He J, Niu L
BMC Cancer 2019 Nov 12;19(1):1091. doi: 10.1186/s12885-019-6311-z. PMID: 31718602Free PMC Article
Feng SH, Yang ST
Diagn Interv Radiol 2019 Jul;25(4):270-279. doi: 10.5152/dir.2019.18458. PMID: 31295144Free PMC Article

Clinical prediction guides

Lavery JA, Boutros PC, Scott JM, Tammela T, Moskowitz CS, Jones LW
J Clin Oncol 2023 Nov 10;41(32):4982-4992. Epub 2023 Aug 31 doi: 10.1200/JCO.23.00058. PMID: 37651670
Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Cheung DST, Takemura N, Lam TC, Ho JCM, Deng W, Smith R, Yan Y, Lee AWM, Lin CC
Integr Cancer Ther 2021 Jan-Dec;20:15347354211033352. doi: 10.1177/15347354211033352. PMID: 34549648Free PMC Article
Wang YN, Zeng ZL, Lu J, Wang Y, Liu ZX, He MM, Zhao Q, Wang ZX, Li T, Lu YX, Wu QN, Yu K, Wang F, Pu HY, Li B, Jia WH, Shi M, Xie D, Kang TB, Huang P, Ju HQ, Xu RH
Oncogene 2018 Nov;37(46):6025-6040. Epub 2018 Jul 11 doi: 10.1038/s41388-018-0384-z. PMID: 29995871
Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, Hazell S, Eichler-Jonsson C, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Jabbar F, Spain L, Lall S, Guarch R, Falzon M, Proctor I, Pickering L, Gore M, Watkins TBK, Ward S, Stewart A, DiNatale R, Becerra MF, Reznik E, Hsieh JJ, Richmond TA, Mayhew GF, Hill SM, McNally CD, Jones C, Rosenbaum H, Stanislaw S, Burgess DL, Alexander NR, Swanton C; PEACE; TRACERx Renal Consortium
Cell 2018 Apr 19;173(3):581-594.e12. Epub 2018 Apr 12 doi: 10.1016/j.cell.2018.03.057. PMID: 29656895Free PMC Article

Recent systematic reviews

Doyle E, Killean AJ, Harrow S, Phillips ID
Radiother Oncol 2024 Jul;196:110288. Epub 2024 Apr 20 doi: 10.1016/j.radonc.2024.110288. PMID: 38648995
Allen I, Hassan H, Sofianopoulou E, Eccles D, Turnbull C, Tischkowitz M, Pharoah P, Antoniou AC
Breast Cancer Res 2023 Feb 10;25(1):18. doi: 10.1186/s13058-023-01610-x. PMID: 36765408Free PMC Article
Knight J, Ratnasingham K
Int J Surg 2015 Jul;19:137-45. Epub 2015 May 6 doi: 10.1016/j.ijsu.2015.04.084. PMID: 25958295
Young ER, Diakos E, Khalid-Raja M, Mehanna H
Clin Otolaryngol 2015 Jun;40(3):208-18. doi: 10.1111/coa.12348. PMID: 25358605
Gupta D, Lis CG
Nutr J 2010 Dec 22;9:69. doi: 10.1186/1475-2891-9-69. PMID: 21176210Free PMC Article

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