U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal flow cytometry test result

MedGen UID:
1614386
•Concept ID:
C4531050
•
Finding
Synonym: Abnormal flow cytometry test rest
 
HPO: HP:0031550

Definition

Any abnormal result of flow cytometry, a method that suspends cells in a stream of fluid and passes them through an electronic detection apparatus in order to assess cell count or measure biomarkers or surface molecules. [from HPO]

Professional guidelines

PubMed

Personalised management of women with cervical abnormalities using a clinical decision support scoring system.
Kyrgiou M, Pouliakis A, Panayiotides JG, Margari N, Bountris P, Valasoulis G, Paraskevaidi M, Bilirakis E, Nasioutziki M, Loufopoulos A, Haritou M, Koutsouris DD, Karakitsos P, Paraskevaidis E
Gynecol Oncol 2016 Apr;141(1):29-35. doi: 10.1016/j.ygyno.2015.12.032. PMID: 27016226
Utility of flow cytometry of cerebrospinal fluid as a screening tool in the diagnosis of central nervous system lymphoma.
Pittman M, Treese S, Chen L, Frater JL, Nguyen TT, Hassan A, Kreisel F
Arch Pathol Lab Med 2013 Nov;137(11):1610-8. doi: 10.5858/arpa.2012-0313-OA. PMID: 24168498
Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: results of the first 2 years.
Kwan A, Church JA, Cowan MJ, Agarwal R, Kapoor N, Kohn DB, Lewis DB, McGhee SA, Moore TB, Stiehm ER, Porteus M, Aznar CP, Currier R, Lorey F, Puck JM
J Allergy Clin Immunol 2013 Jul;132(1):140-50. doi: 10.1016/j.jaci.2013.04.024. PMID: 23810098Free PMC Article

Recent clinical studies

Etiology

Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, Mumin MA, Zhou X, Chen Y, Shu G, Yao G, Chen M, Lu J, Zhang L, Liu Y, Zhao Y, Bao J, Chen W, Luo J, Li X, Chen Z, Cao J
J Transl Med 2023 May 23;21(1):343. doi: 10.1186/s12967-023-04161-z. PMID: 37221577Free PMC Article
p16(INK4A) flow cytometry of exfoliated cervical cells: Its role in quantitative pathology and clinical diagnosis of squamous intraepithelial lesions.
He Y, Shi J, Zhao H, Wang Y, Zhang C, Han S, He Q, Li X, Li S, Wang W, Yi M, Hu X, Xing Z, Han H, Gao Y, Zhou Q, Lu L, Guo J, Cao H, Lu C, Hou Y, Chen D, Yang F, Lei P, Di W, Qian J, Xia Y, Zhang Y, Deng Y, Zhu J, Xu C
Clin Transl Med 2023 Mar;13(3):e1209. doi: 10.1002/ctm2.1209. PMID: 36881611Free PMC Article
Vitamin D Levels and Sperm DNA Fragmentation.
Blaseg E
S D Med 2022 Oct;75(10):448. PMID: 36889259
Evaluation of measurable residual disease in multiple myeloma by multiparametric flow cytometry: Current paradigm, guidelines, and future applications.
Soh KT, Wallace PK
Int J Lab Hematol 2021 Jul;43 Suppl 1:43-53. doi: 10.1111/ijlh.13562. PMID: 34288449
MDS prognostic scoring systems – past, present, and future.
Jonas BA, Greenberg PL
Best Pract Res Clin Haematol 2015 Mar;28(1):3-13. Epub 2014 Nov 11 doi: 10.1016/j.beha.2014.11.001. PMID: 25659725Free PMC Article

Diagnosis

Multiparameter flow cytometry and ClonoSEQ correlation to evaluate precursor B-lymphoblastic leukemia measurable residual disease.
Momen N, Tario J, Fu K, Qian YW
J Hematop 2023 Jun;16(2):85-94. Epub 2023 Apr 14 doi: 10.1007/s12308-023-00544-9. PMID: 38175444
Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, Mumin MA, Zhou X, Chen Y, Shu G, Yao G, Chen M, Lu J, Zhang L, Liu Y, Zhao Y, Bao J, Chen W, Luo J, Li X, Chen Z, Cao J
J Transl Med 2023 May 23;21(1):343. doi: 10.1186/s12967-023-04161-z. PMID: 37221577Free PMC Article
p16(INK4A) flow cytometry of exfoliated cervical cells: Its role in quantitative pathology and clinical diagnosis of squamous intraepithelial lesions.
He Y, Shi J, Zhao H, Wang Y, Zhang C, Han S, He Q, Li X, Li S, Wang W, Yi M, Hu X, Xing Z, Han H, Gao Y, Zhou Q, Lu L, Guo J, Cao H, Lu C, Hou Y, Chen D, Yang F, Lei P, Di W, Qian J, Xia Y, Zhang Y, Deng Y, Zhu J, Xu C
Clin Transl Med 2023 Mar;13(3):e1209. doi: 10.1002/ctm2.1209. PMID: 36881611Free PMC Article
Flow cytometry-Recognizing unusual populations in leukemia and lymphoma diagnosis.
Keeney M, Hedley BD, Chin-Yee IH
Int J Lab Hematol 2017 May;39 Suppl 1:86-92. doi: 10.1111/ijlh.12666. PMID: 28447408
Interphase Chromosome Flow-FISH.
Keyvanfar K, Weed J, Swamy P, Kajigaya S, Calado RT, Young NS
Blood 2012 Oct 11;120(15):e54-9. Epub 2012 Aug 29 doi: 10.1182/blood-2012-05-434266. PMID: 22932794Free PMC Article

Therapy

Identification of biomarkers in patients with rheumatoid arthritis responsive to DMARDs but with progressive bone erosion.
Marasco E, Fabbriciani G, Rotunno L, Longhi M, De Luca P, de Girolamo L, Colombini A
Front Immunol 2023;14:1254139. Epub 2023 Sep 19 doi: 10.3389/fimmu.2023.1254139. PMID: 37809106Free PMC Article
Effect of Training on Vascular Function and Repair in Heart Failure With Preserved Ejection Fraction.
Gevaert AB, Böhm B, Hartmann H, Goovaerts I, Stoop T, Van De Heyning CM, Beckers PJ, Baldassarri F, Mueller S, Oberhoffer R, Duvinage A, Haykowsky MJ, Wisløff U, Adams V, Pieske B, Halle M, Van Craenenbroeck EM
JACC Heart Fail 2023 Apr;11(4):454-464. Epub 2023 Mar 1 doi: 10.1016/j.jchf.2022.12.011. PMID: 36892488
Autologous Stem Cell Transplantation for Patients with Multiple Myeloma with Translocation (4;14): The MD Anderson Cancer Center Experience.
Pasvolsky O, Gaballa MR, Milton DR, Masood A, Sami SS, Tanner MR, Bashir Q, Srour S, Saini N, Ramdial J, Nieto Y, Tang G, Lin P, Lee HC, Patel KK, Kebriaei P, Thomas SK, Weber DM, Orlowski RZ, Shpall EJ, Champlin RE, Qazilbash MH
Transplant Cell Ther 2023 Apr;29(4):260.e1-260.e6. Epub 2023 Jan 14 doi: 10.1016/j.jtct.2023.01.010. PMID: 36646323Free PMC Article
Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis.
Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D
Arthritis Res Ther 2021 Jan 6;23(1):10. doi: 10.1186/s13075-020-02383-w. PMID: 33407866Free PMC Article
MDS prognostic scoring systems – past, present, and future.
Jonas BA, Greenberg PL
Best Pract Res Clin Haematol 2015 Mar;28(1):3-13. Epub 2014 Nov 11 doi: 10.1016/j.beha.2014.11.001. PMID: 25659725Free PMC Article

Prognosis

Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, Mumin MA, Zhou X, Chen Y, Shu G, Yao G, Chen M, Lu J, Zhang L, Liu Y, Zhao Y, Bao J, Chen W, Luo J, Li X, Chen Z, Cao J
J Transl Med 2023 May 23;21(1):343. doi: 10.1186/s12967-023-04161-z. PMID: 37221577Free PMC Article
p16(INK4A) flow cytometry of exfoliated cervical cells: Its role in quantitative pathology and clinical diagnosis of squamous intraepithelial lesions.
He Y, Shi J, Zhao H, Wang Y, Zhang C, Han S, He Q, Li X, Li S, Wang W, Yi M, Hu X, Xing Z, Han H, Gao Y, Zhou Q, Lu L, Guo J, Cao H, Lu C, Hou Y, Chen D, Yang F, Lei P, Di W, Qian J, Xia Y, Zhang Y, Deng Y, Zhu J, Xu C
Clin Transl Med 2023 Mar;13(3):e1209. doi: 10.1002/ctm2.1209. PMID: 36881611Free PMC Article
Evaluation of measurable residual disease in multiple myeloma by multiparametric flow cytometry: Current paradigm, guidelines, and future applications.
Soh KT, Wallace PK
Int J Lab Hematol 2021 Jul;43 Suppl 1:43-53. doi: 10.1111/ijlh.13562. PMID: 34288449
Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry.
Alaterre E, Raimbault S, Garcia JM, Rème T, Requirand G, Klein B, Moreaux J
Cytometry B Clin Cytom 2018 May;94(3):484-492. Epub 2017 Sep 19 doi: 10.1002/cyto.b.21590. PMID: 28865180
MDS prognostic scoring systems – past, present, and future.
Jonas BA, Greenberg PL
Best Pract Res Clin Haematol 2015 Mar;28(1):3-13. Epub 2014 Nov 11 doi: 10.1016/j.beha.2014.11.001. PMID: 25659725Free PMC Article

Clinical prediction guides

Multiparameter flow cytometry and ClonoSEQ correlation to evaluate precursor B-lymphoblastic leukemia measurable residual disease.
Momen N, Tario J, Fu K, Qian YW
J Hematop 2023 Jun;16(2):85-94. Epub 2023 Apr 14 doi: 10.1007/s12308-023-00544-9. PMID: 38175444
Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, Mumin MA, Zhou X, Chen Y, Shu G, Yao G, Chen M, Lu J, Zhang L, Liu Y, Zhao Y, Bao J, Chen W, Luo J, Li X, Chen Z, Cao J
J Transl Med 2023 May 23;21(1):343. doi: 10.1186/s12967-023-04161-z. PMID: 37221577Free PMC Article
Effect of Training on Vascular Function and Repair in Heart Failure With Preserved Ejection Fraction.
Gevaert AB, Böhm B, Hartmann H, Goovaerts I, Stoop T, Van De Heyning CM, Beckers PJ, Baldassarri F, Mueller S, Oberhoffer R, Duvinage A, Haykowsky MJ, Wisløff U, Adams V, Pieske B, Halle M, Van Craenenbroeck EM
JACC Heart Fail 2023 Apr;11(4):454-464. Epub 2023 Mar 1 doi: 10.1016/j.jchf.2022.12.011. PMID: 36892488
p16(INK4A) flow cytometry of exfoliated cervical cells: Its role in quantitative pathology and clinical diagnosis of squamous intraepithelial lesions.
He Y, Shi J, Zhao H, Wang Y, Zhang C, Han S, He Q, Li X, Li S, Wang W, Yi M, Hu X, Xing Z, Han H, Gao Y, Zhou Q, Lu L, Guo J, Cao H, Lu C, Hou Y, Chen D, Yang F, Lei P, Di W, Qian J, Xia Y, Zhang Y, Deng Y, Zhu J, Xu C
Clin Transl Med 2023 Mar;13(3):e1209. doi: 10.1002/ctm2.1209. PMID: 36881611Free PMC Article
MDS prognostic scoring systems – past, present, and future.
Jonas BA, Greenberg PL
Best Pract Res Clin Haematol 2015 Mar;28(1):3-13. Epub 2014 Nov 11 doi: 10.1016/j.beha.2014.11.001. PMID: 25659725Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...