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Increased circulating beta-C-terminal telopeptide concentration

MedGen UID:
1614490
•Concept ID:
C4531129
•
Finding
Synonyms: Increased circulating beta-C-terminal telopeptide level; Increased circulating beta-CrossLaps level; Increased circulating beta-CTx level
 
HPO: HP:0031425

Definition

A abnormal elevation above the normal concentration of beta-C-terminal telopeptide of type I collagen in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased circulating beta-C-terminal telopeptide concentration

Recent clinical studies

Etiology

Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.
Hartley A, Paternoster L, Evans DM, Fraser WD, Tang J, Lawlor DA, Tobias JH, Gregson CL
Clin Endocrinol (Oxf) 2020 Jan;92(1):29-37. Epub 2019 Nov 20 doi: 10.1111/cen.14119. PMID: 31667854Free PMC Article

Clinical prediction guides

Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.
Hartley A, Paternoster L, Evans DM, Fraser WD, Tang J, Lawlor DA, Tobias JH, Gregson CL
Clin Endocrinol (Oxf) 2020 Jan;92(1):29-37. Epub 2019 Nov 20 doi: 10.1111/cen.14119. PMID: 31667854Free PMC Article

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