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Posterior Subcapsular Cataract Grade 2

MedGen UID:
1614594
•Concept ID:
C4525732
•
Disease or Syndrome

Definition

A stage of posterior subcapsular cataract characterized by 30% of the posterior capsule obscured by opacity. (Modified LOCS II) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior Subcapsular Cataract Grade 2

Professional guidelines

PubMed

Cataract in renal transplantation recipients with combination ciclosporin treatment.
Nishimoto K, Sasaki K, Yamamura T, Ishikawa I, Shinoda A
Lens Eye Toxic Res 1992;9(3-4):455-67. PMID: 1301797

Recent clinical studies

Etiology

Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
The prevalence of cataract in a population with and without type 2 diabetes mellitus.
Olafsdottir E, Andersson DK, Stefánsson E
Acta Ophthalmol 2012 Jun;90(4):334-40. Epub 2011 Dec 16 doi: 10.1111/j.1755-3768.2011.02326.x. PMID: 22176834
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058
The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.
Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

Diagnosis

Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
The prevalence of cataract in a population with and without type 2 diabetes mellitus.
Olafsdottir E, Andersson DK, Stefánsson E
Acta Ophthalmol 2012 Jun;90(4):334-40. Epub 2011 Dec 16 doi: 10.1111/j.1755-3768.2011.02326.x. PMID: 22176834
Influence of cataract morphology on straylight and contrast sensitivity and its relevance to fitness to drive.
Bal T, Coeckelbergh T, Van Looveren J, Rozema JJ, Tassignon MJ
Ophthalmologica 2011;225(2):105-11. Epub 2010 Sep 24 doi: 10.1159/000317076. PMID: 20881445
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058
Quantitating cataract and nuclear brunescence, the Harvard and LOCS systems.
Chylack LT Jr, Wolfe JK, Friend J, Khu PM, Singer DM, McCarthy D, del Carmen J, Rosner B
Optom Vis Sci 1993 Nov;70(11):886-95. doi: 10.1097/00006324-199311000-00005. PMID: 8302524

Therapy

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.
Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601
Evaluating the associations between obesity and age-related cataract: a Mendelian randomization study.
Tan AG, Kifley A, Flood VM, Holliday EG, Scott RJ, Cumming RG, Mitchell P, Wang JJ
Am J Clin Nutr 2019 Oct 1;110(4):969-976. doi: 10.1093/ajcn/nqz167. PMID: 31401654
Use of inhaled and oral corticosteroids and the long-term risk of cataract.
Wang JJ, Rochtchina E, Tan AG, Cumming RG, Leeder SR, Mitchell P
Ophthalmology 2009 Apr;116(4):652-7. Epub 2009 Feb 25 doi: 10.1016/j.ophtha.2008.12.001. PMID: 19243828
Plasma antioxidant vitamins and carotenoids and age-related cataract.
Gale CR, Hall NF, Phillips DI, Martyn CN
Ophthalmology 2001 Nov;108(11):1992-8. doi: 10.1016/s0161-6420(01)00833-8. PMID: 11713067
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Prognosis

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.
Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601
Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
Lens retrodots and vacuoles and their associations with the prevalence and incidence of age-related cataract.
Tan AG, Mitchell P, Rochtchina E, Hong T, Cumming RG, Wang JJ
Eye (Lond) 2012 Apr;26(4):568-75. Epub 2011 Dec 23 doi: 10.1038/eye.2011.349. PMID: 22193877Free PMC Article
Myopia and incident cataract and cataract surgery: the blue mountains eye study.
Younan C, Mitchell P, Cumming RG, Rochtchina E, Wang JJ
Invest Ophthalmol Vis Sci 2002 Dec;43(12):3625-32. PMID: 12454028
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Clinical prediction guides

Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Refractive changes in nuclear, cortical and posterior subcapsular cataracts. effect of the type and grade.
Díez Ajenjo MA, García Domene MC, Peris Martínez C
J Optom 2015 Apr-Jun;8(2):86-92. Epub 2014 Sep 2 doi: 10.1016/j.optom.2014.07.006. PMID: 25192610Free PMC Article
The prevalence of cataract in a population with and without type 2 diabetes mellitus.
Olafsdottir E, Andersson DK, Stefánsson E
Acta Ophthalmol 2012 Jun;90(4):334-40. Epub 2011 Dec 16 doi: 10.1111/j.1755-3768.2011.02326.x. PMID: 22176834
The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.
Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486
Quantitating cataract and nuclear brunescence, the Harvard and LOCS systems.
Chylack LT Jr, Wolfe JK, Friend J, Khu PM, Singer DM, McCarthy D, del Carmen J, Rosner B
Optom Vis Sci 1993 Nov;70(11):886-95. doi: 10.1097/00006324-199311000-00005. PMID: 8302524

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