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Intrapulmonary shunt

MedGen UID:
1614836
Concept ID:
C0489642
Finding
Synonym: Intrapulmonary shunting
 
HPO: HP:0031225

Definition

Blood flow through a region of the lung in which little or no ventilation takes place, resulting in reduced oxygenation of the blood leaving the lungs. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntrapulmonary shunt

Professional guidelines

PubMed

Szpilman D, Morgan PJ
Chest 2021 Apr;159(4):1473-1483. Epub 2020 Oct 14 doi: 10.1016/j.chest.2020.10.007. PMID: 33065105
Montisci A, Maj G, Zangrillo A, Winterton D, Pappalardo F
ASAIO J 2015 May-Jun;61(3):227-36. doi: 10.1097/MAT.0000000000000207. PMID: 25923575
Kass LJ, Apkon M
Curr Opin Pediatr 1998 Jun;10(3):284-90. doi: 10.1097/00008480-199806000-00011. PMID: 9716891

Recent clinical studies

Etiology

Harbut P, Prisk GK, Lindwall R, Hamzei S, Palmgren J, Farrow CE, Hedenstierna G, Amis TC, Malhotra A, Wagner PD, Kairaitis K
Eur Respir J 2023 Jan;61(1) Epub 2023 Jan 27 doi: 10.1183/13993003.01117-2022. PMID: 36137595Free PMC Article
Russell-Jones E, Grammatikopoulos T, Greenough A, Dhawan A, Dassios T
Respir Med 2021 Apr-May;180:106372. Epub 2021 Mar 23 doi: 10.1016/j.rmed.2021.106372. PMID: 33780759
Radermacher P, Maggiore SM, Mercat A
Am J Respir Crit Care Med 2017 Oct 15;196(8):964-984. doi: 10.1164/rccm.201610-2156SO. PMID: 28406724
Madden D, Ljubkovic M, Dujic Z
Echocardiography 2015 Feb;32 Suppl 3:S205-10. doi: 10.1111/echo.12815. PMID: 25693625
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954

Diagnosis

Radermacher P, Maggiore SM, Mercat A
Am J Respir Crit Care Med 2017 Oct 15;196(8):964-984. doi: 10.1164/rccm.201610-2156SO. PMID: 28406724
Madden D, Ljubkovic M, Dujic Z
Echocardiography 2015 Feb;32 Suppl 3:S205-10. doi: 10.1111/echo.12815. PMID: 25693625
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954
Lange PA, Stoller JK
Ann Intern Med 1995 Apr 1;122(7):521-9. doi: 10.7326/0003-4819-122-7-199504010-00008. PMID: 7872588
Dal Nogare AR
Am J Med Sci 1989 Dec;298(6):413-30. doi: 10.1097/00000441-198912000-00011. PMID: 2688415

Therapy

Schorer R, Dombret AL, Hagerman A, Bédat B, Putzu A
Br J Anaesth 2023 Jan;130(1):e92-e105. Epub 2022 Oct 26 doi: 10.1016/j.bja.2022.08.039. PMID: 36939497
Peták F, Balogh ÁL, Hankovszky P, Fodor GH, Tolnai J, Südy R, Kovács BN, Molnár A, Babik B
J Cardiothorac Vasc Anesth 2022 Apr;36(4):1047-1055. Epub 2021 Jul 24 doi: 10.1053/j.jvca.2021.07.033. PMID: 34404593
Uchida H, Sakamoto S, Kasahara M, Kudo H, Okajima H, Nio M, Umeshita K, Ohdan H, Egawa H, Uemoto S; Japanese Liver Transplantation Society
Liver Transpl 2021 Feb;27(2):236-247. Epub 2020 Aug 6 doi: 10.1002/lt.25805. PMID: 32463947
Goldhill DR, Imhoff M, McLean B, Waldmann C
Am J Crit Care 2007 Jan;16(1):50-61; quiz 62. PMID: 17192526
Dal Nogare AR
Am J Med Sci 1989 Dec;298(6):413-30. doi: 10.1097/00000441-198912000-00011. PMID: 2688415

Prognosis

Farrow CE, Robles RA, Prisk GK, Harbut P, Malhotra A, Amis TC, Wagner PD, Kairaitis K
J Appl Physiol (1985) 2023 Nov 1;135(5):1012-1022. Epub 2023 Sep 28 doi: 10.1152/japplphysiol.00267.2023. PMID: 37767555Free PMC Article
Cartin-Ceba R, Swanson KL, Krowka MJ
Chest 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924. PMID: 24008954
Light RB
Semin Respir Infect 1999 Sep;14(3):218-26. PMID: 10501309
Lange PA, Stoller JK
Ann Intern Med 1995 Apr 1;122(7):521-9. doi: 10.7326/0003-4819-122-7-199504010-00008. PMID: 7872588
Wahba RW
Can J Anaesth 1991 Apr;38(3):384-400. doi: 10.1007/BF03007630. PMID: 2036700

Clinical prediction guides

Farrow CE, Robles RA, Prisk GK, Harbut P, Malhotra A, Amis TC, Wagner PD, Kairaitis K
J Appl Physiol (1985) 2023 Nov 1;135(5):1012-1022. Epub 2023 Sep 28 doi: 10.1152/japplphysiol.00267.2023. PMID: 37767555Free PMC Article
Lovering AT, Stickland MK, Eldridge MW
Adv Exp Med Biol 2006;588:31-45. doi: 10.1007/978-0-387-34817-9_4. PMID: 17089877
Lange PA, Stoller JK
Ann Intern Med 1995 Apr 1;122(7):521-9. doi: 10.7326/0003-4819-122-7-199504010-00008. PMID: 7872588
Warltier DC, Pagel PS
Anesth Analg 1992 Oct;75(4 Suppl):S17-29; discussion S29-31. PMID: 1524236
Wahba RW
Can J Anaesth 1991 Apr;38(3):384-400. doi: 10.1007/BF03007630. PMID: 2036700

Recent systematic reviews

Schorer R, Dombret AL, Hagerman A, Bédat B, Putzu A
Br J Anaesth 2023 Jan;130(1):e92-e105. Epub 2022 Oct 26 doi: 10.1016/j.bja.2022.08.039. PMID: 36939497
Kim KN, Kim DW, Jeong MA, Sin YH, Lee SK
BMC Anesthesiol 2016 Aug 31;16(1):72. doi: 10.1186/s12871-016-0238-6. PMID: 27581657Free PMC Article
Módolo NS, Módolo MP, Marton MA, Volpato E, Monteiro Arantes V, do Nascimento Junior P, El Dib RP
Cochrane Database Syst Rev 2013 Jul 11;2013(7):CD006313. doi: 10.1002/14651858.CD006313.pub3. PMID: 23846831Free PMC Article

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