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Recurrent Soft Tissue Sarcoma

MedGen UID:
1616283
•Concept ID:
C4522237
•
Neoplastic Process

Definition

The reemergence of soft tissue sarcoma after a period of remission. [from NCI]

Professional guidelines

PubMed

Reirradiation in Conservative Salvage of Recurrent Soft-tissue Sarcoma: An Analysis of Treatment Efficacy and Toxicities.
Braschi EL, Kharod SM, Morris CG, Spiguel AR, Gibbs CP, Scarborough MT, Zlotecki RA
Am J Clin Oncol 2021 Dec 1;44(12):624-628. doi: 10.1097/COC.0000000000000874. PMID: 34753882
Management of locally recurrent soft tissue sarcoma after prior surgery and radiation therapy.
Hohenberger P, Schwarzbach MH
Recent Results Cancer Res 2009;179:271-83. doi: 10.1007/978-3-540-77960-5_17. PMID: 19230546
Soft-tissue sarcoma of the extremities. MR appearance of post-treatment changes and local recurrences.
Varma DG, Jackson EF, Pollock RE, Benjamin RS
Magn Reson Imaging Clin N Am 1995 Nov;3(4):695-712. PMID: 8564690

Recent clinical studies

Etiology

Diagnostic performance of MRI in detecting locally recurrent soft tissue sarcoma: systematic review and meta-analysis.
Kwee RM, Kwee TC
Eur Radiol 2022 Jun;32(6):3915-3930. Epub 2022 Jan 12 doi: 10.1007/s00330-021-08457-w. PMID: 35020015
Gadolinium-based Contrast Agents Improve Detection of Recurrent Soft-Tissue Sarcoma at MRI.
Amini B, Murphy WA Jr, Haygood TM, Kumar R, McEnery KW, Madewell JE, Mujtaba BM, Wei W, Costelloe CM
Radiol Imaging Cancer 2020 Mar;2(2):e190046. Epub 2020 Mar 27 doi: 10.1148/rycan.2020190046. PMID: 33778705Free PMC Article
Can we use MRI to detect clinically silent recurrent soft-tissue sarcoma?
Hirschmann A, van Praag VM, Haas RL, van de Sande MAJ, Bloem JL
Eur Radiol 2020 Sep;30(9):4724-4733. Epub 2020 Apr 20 doi: 10.1007/s00330-020-06810-z. PMID: 32314057
Management of locally recurrent soft tissue sarcoma after prior surgery and radiation therapy.
Hohenberger P, Schwarzbach MH
Recent Results Cancer Res 2009;179:271-83. doi: 10.1007/978-3-540-77960-5_17. PMID: 19230546
Brachytherapy for locally recurrent soft-tissue sarcoma.
Janjan N, Crane C, Delclos M, Ballo M
Am J Clin Oncol 2002 Feb;25(1):9-15. doi: 10.1097/00000421-200202000-00002. PMID: 11823688

Diagnosis

Head-to-head evaluation of [(18)F]FDG and [(68) Ga]Ga-DOTA-FAPI-04 PET/CT in recurrent soft tissue sarcoma.
Gu B, Liu X, Wang S, Xu X, Liu X, Hu S, Yan W, Luo Z, Song S
Eur J Nucl Med Mol Imaging 2022 Jul;49(8):2889-2901. Epub 2022 Feb 3 doi: 10.1007/s00259-022-05700-4. PMID: 35113192Free PMC Article
Diagnostic performance of MRI in detecting locally recurrent soft tissue sarcoma: systematic review and meta-analysis.
Kwee RM, Kwee TC
Eur Radiol 2022 Jun;32(6):3915-3930. Epub 2022 Jan 12 doi: 10.1007/s00330-021-08457-w. PMID: 35020015
Gadolinium-based Contrast Agents Improve Detection of Recurrent Soft-Tissue Sarcoma at MRI.
Amini B, Murphy WA Jr, Haygood TM, Kumar R, McEnery KW, Madewell JE, Mujtaba BM, Wei W, Costelloe CM
Radiol Imaging Cancer 2020 Mar;2(2):e190046. Epub 2020 Mar 27 doi: 10.1148/rycan.2020190046. PMID: 33778705Free PMC Article
Can we use MRI to detect clinically silent recurrent soft-tissue sarcoma?
Hirschmann A, van Praag VM, Haas RL, van de Sande MAJ, Bloem JL
Eur Radiol 2020 Sep;30(9):4724-4733. Epub 2020 Apr 20 doi: 10.1007/s00330-020-06810-z. PMID: 32314057
Soft-tissue sarcoma of the extremities. MR appearance of post-treatment changes and local recurrences.
Varma DG, Jackson EF, Pollock RE, Benjamin RS
Magn Reson Imaging Clin N Am 1995 Nov;3(4):695-712. PMID: 8564690

Therapy

Diagnostic performance of MRI in detecting locally recurrent soft tissue sarcoma: systematic review and meta-analysis.
Kwee RM, Kwee TC
Eur Radiol 2022 Jun;32(6):3915-3930. Epub 2022 Jan 12 doi: 10.1007/s00330-021-08457-w. PMID: 35020015
Reirradiation in Conservative Salvage of Recurrent Soft-tissue Sarcoma: An Analysis of Treatment Efficacy and Toxicities.
Braschi EL, Kharod SM, Morris CG, Spiguel AR, Gibbs CP, Scarborough MT, Zlotecki RA
Am J Clin Oncol 2021 Dec 1;44(12):624-628. doi: 10.1097/COC.0000000000000874. PMID: 34753882
Impact of Acridine Orange in Patients With Local Recurrent Soft Tissue Sarcoma.
Tsuchie H, Emori M, Miyakoshi N, Okada K, Nagasawa H, Murahashi Y, Mizushima E, Shimizu J, Yamashita T, Shimada Y
In Vivo 2020 Sep-Oct;34(5):2745-2750. doi: 10.21873/invivo.12097. PMID: 32871809Free PMC Article
Trabectedin for inoperable or recurrent soft tissue sarcoma in adult patients: a retrospective cohort study.
Angarita FA, Cannell AJ, Abdul Razak AR, Dickson BC, Blackstein ME
BMC Cancer 2016 Jan 19;16:30. doi: 10.1186/s12885-016-2054-2. PMID: 26786213Free PMC Article
Trabectedin for advanced soft tissue sarcomas: a single institution experience.
Gounaris I, Hatcher HM, Davidson D, Sherbourne K, Alam S, Zaki KA, Horan G, Earl HM
Future Oncol 2014 Aug;10(11):1843-51. Epub 2014 Jan 22 doi: 10.2217/fon.14.10. PMID: 24450573

Prognosis

Impact of Acridine Orange in Patients With Local Recurrent Soft Tissue Sarcoma.
Tsuchie H, Emori M, Miyakoshi N, Okada K, Nagasawa H, Murahashi Y, Mizushima E, Shimizu J, Yamashita T, Shimada Y
In Vivo 2020 Sep-Oct;34(5):2745-2750. doi: 10.21873/invivo.12097. PMID: 32871809Free PMC Article
The construction and analysis of tumor-infiltrating immune cell and ceRNA networks in recurrent soft tissue sarcoma.
Huang R, Meng T, Chen R, Yan P, Zhang J, Hu P, Zhu X, Yin H, Song D, Huang Z
Aging (Albany NY) 2019 Nov 18;11(22):10116-10143. doi: 10.18632/aging.102424. PMID: 31739284Free PMC Article
Management of locally recurrent soft-tissue sarcoma after prior surgery and radiation therapy.
Torres MA, Ballo MT, Butler CE, Feig BW, Cormier JN, Lewis VO, Pollock RE, Pisters PW, Zagars GK
Int J Radiat Oncol Biol Phys 2007 Mar 15;67(4):1124-9. Epub 2007 Jan 8 doi: 10.1016/j.ijrobp.2006.10.036. PMID: 17208389
Completely resected recurrent soft tissue sarcoma: primary anatomic site governs outcomes.
Stojadinovic A, Yeh A, Brennan MF
J Am Coll Surg 2002 Apr;194(4):436-47. doi: 10.1016/s1072-7515(02)01120-1. PMID: 11949749
Management of primary and recurrent soft-tissue sarcoma of the retroperitoneum.
Jaques DP, Coit DG, Hajdu SI, Brennan MF
Ann Surg 1990 Jul;212(1):51-9. doi: 10.1097/00000658-199007000-00008. PMID: 2363604Free PMC Article

Clinical prediction guides

Gadolinium-based Contrast Agents Improve Detection of Recurrent Soft-Tissue Sarcoma at MRI.
Amini B, Murphy WA Jr, Haygood TM, Kumar R, McEnery KW, Madewell JE, Mujtaba BM, Wei W, Costelloe CM
Radiol Imaging Cancer 2020 Mar;2(2):e190046. Epub 2020 Mar 27 doi: 10.1148/rycan.2020190046. PMID: 33778705Free PMC Article
Oncological outcome after hyperthermic isolated limb perfusion for primarily unresectable versus locally recurrent soft tissue sarcoma of extremities.
Vassos N, Brunner M, Perrakis A, Göhl J, Grützmann R, Hohenberger W, Croner RS
Surg Oncol 2020 Dec;35:162-168. Epub 2020 Aug 12 doi: 10.1016/j.suronc.2020.08.010. PMID: 32882523
Implications of staged reconstruction and adjuvant brachytherapy in the treatment of recurrent soft tissue sarcoma.
Naghavi AO, Gonzalez RJ, Scott JG, Mullinax JE, Abuodeh YA, Kim Y, Binitie O, Ahmed KA, Bui MM, Saini AS, Zager JS, Biagioli MC, Letson D, Harrison LB, Fernandez DC
Brachytherapy 2016 Jul-Aug;15(4):495-503. Epub 2016 May 12 doi: 10.1016/j.brachy.2016.03.013. PMID: 27180128Free PMC Article
Completely resected recurrent soft tissue sarcoma: primary anatomic site governs outcomes.
Stojadinovic A, Yeh A, Brennan MF
J Am Coll Surg 2002 Apr;194(4):436-47. doi: 10.1016/s1072-7515(02)01120-1. PMID: 11949749
Management of primary and recurrent soft-tissue sarcoma of the retroperitoneum.
Jaques DP, Coit DG, Hajdu SI, Brennan MF
Ann Surg 1990 Jul;212(1):51-9. doi: 10.1097/00000658-199007000-00008. PMID: 2363604Free PMC Article

Recent systematic reviews

Diagnostic performance of MRI in detecting locally recurrent soft tissue sarcoma: systematic review and meta-analysis.
Kwee RM, Kwee TC
Eur Radiol 2022 Jun;32(6):3915-3930. Epub 2022 Jan 12 doi: 10.1007/s00330-021-08457-w. PMID: 35020015

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