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Bacterial cell casts

MedGen UID:
1617354
•Concept ID:
C4531281
•
Finding
HPO: HP:0031204

Definition

A type of urinary cast that contain bacteria. Bacterial casts can be difficult to identify and can be distinguished from other types of casts using phase contrast microscopy. Bacterial casts are diagnostic of acute pyelonephritis or intrinsic renal infection. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBacterial cell casts

Professional guidelines

PubMed

Development of a xanthan gum film for the possible treatment of vaginal infections.
Villar-Padilla A, Del Prado-Audelo MAL, González-Torres M, Giraldo-Gomez DM, Caballero-Florán IH, González-Del Carmen M, Sharifi-Rad J, Figueroa-González G, Reyes-Hernández OD, Cortés H, Leyva-Gómez G
Cell Mol Biol (Noisy-le-grand) 2021 Jan 31;67(1):80-88. doi: 10.14715/cmb/2021.67.1.12. PMID: 34817364
Novel polymeric dressing to the treatment of infected chronic wound.
Garms BC, Borges FA, de Barros NR, Marcelino MY, Leite MN, Del Arco MC, de Souza Salvador SL, Pegorin GS, Oliveira KSM, Frade MAC, Herculano RD
Appl Microbiol Biotechnol 2019 Jun;103(12):4767-4778. Epub 2019 May 7 doi: 10.1007/s00253-019-09699-x. PMID: 31065753
Bioadhesive polymeric films based on usnic acid for burn wound treatment: Antibacterial and cytotoxicity studies.
Pagano C, Ceccarini MR, Calarco P, Scuota S, Conte C, Primavilla S, Ricci M, Perioli L
Colloids Surf B Biointerfaces 2019 Jun 1;178:488-499. Epub 2019 Mar 5 doi: 10.1016/j.colsurfb.2019.03.001. PMID: 30925372

Recent clinical studies

Etiology

Improved drug delivery and accelerated diabetic wound healing by chondroitin sulfate grafted alginate-based thermoreversible hydrogels.
Shah SA, Sohail M, Khan SA, Kousar M
Mater Sci Eng C Mater Biol Appl 2021 Jul;126:112169. Epub 2021 May 14 doi: 10.1016/j.msec.2021.112169. PMID: 34082970
Biomimetic TiO(2)-chitosan/sodium alginate blended nanocomposite scaffolds for tissue engineering applications.
Kolathupalayam Shanmugam B, Rangaraj S, Subramani K, Srinivasan S, Aicher WK, Venkatachalam R
Mater Sci Eng C Mater Biol Appl 2020 May;110:110710. Epub 2020 Jan 31 doi: 10.1016/j.msec.2020.110710. PMID: 32204022
Drug-induced tubulointerstitial nephritis: hypersensitivity and necroinflammatory pathways.
Eddy AA
Pediatr Nephrol 2020 Apr;35(4):547-554. Epub 2019 Feb 28 doi: 10.1007/s00467-019-04207-9. PMID: 30820701
Bronchoscopic and histologic findings during lymphatic intervention for plastic bronchitis.
Geanacopoulos AT, Savla JJ, Pogoriler J, Piccione J, Phinizy P, DeWitt AG, Blinder JJ, Pinto E, Itkin M, Dori Y, Goldfarb SB
Pediatr Pulmonol 2018 Nov;53(11):1574-1581. Epub 2018 Sep 12 doi: 10.1002/ppul.24161. PMID: 30207430Free PMC Article
Lipopolysaccharide hyporesponsiveness: protective or damaging response to the brain?
Pardon MC
Rom J Morphol Embryol 2015;56(3):903-13. PMID: 26662122

Diagnosis

Drug-induced tubulointerstitial nephritis: hypersensitivity and necroinflammatory pathways.
Eddy AA
Pediatr Nephrol 2020 Apr;35(4):547-554. Epub 2019 Feb 28 doi: 10.1007/s00467-019-04207-9. PMID: 30820701
Urinary tract infections in polycystic kidney disease.
Idrizi A, Barbullushi M, Koroshi A, Dibra M, Bolleku E, Bajrami V, Xhaferri X, Thereska N
Med Arh 2011;65(4):213-5. doi: 10.5455/medarh.2011.65.213-215. PMID: 21950226
Conjugated linoleic acids: are they beneficial or detrimental to health?
Wahle KW, Heys SD, Rotondo D
Prog Lipid Res 2004 Nov;43(6):553-87. doi: 10.1016/j.plipres.2004.08.002. PMID: 15522764
The role of automated urine particle flow cytometry in clinical practice.
Delanghe JR, Kouri TT, Huber AR, Hannemann-Pohl K, Guder WG, Lun A, Sinha P, Stamminger G, Beier L
Clin Chim Acta 2000 Nov;301(1-2):1-18. doi: 10.1016/s0009-8981(00)00342-9. PMID: 11020458
Urinary sediment analyzed by flow cytometry.
Yasui Y, Tatsumi N, Park K, Koezuka T
Cytometry 1995 Mar 15;22(1):75-9. doi: 10.1002/cyto.990220114. PMID: 7587738

Therapy

Pathway Driven Target Selection in Klebsiella pneumoniae: Insights Into Carbapenem Exposure.
Serral F, Pardo AM, Sosa E, Palomino MM, Nicolás MF, Turjanski AG, Ramos PIP, Fernández Do Porto D
Front Cell Infect Microbiol 2022;12:773405. Epub 2022 Jan 31 doi: 10.3389/fcimb.2022.773405. PMID: 35174104Free PMC Article
Development of a xanthan gum film for the possible treatment of vaginal infections.
Villar-Padilla A, Del Prado-Audelo MAL, González-Torres M, Giraldo-Gomez DM, Caballero-Florán IH, González-Del Carmen M, Sharifi-Rad J, Figueroa-González G, Reyes-Hernández OD, Cortés H, Leyva-Gómez G
Cell Mol Biol (Noisy-le-grand) 2021 Jan 31;67(1):80-88. doi: 10.14715/cmb/2021.67.1.12. PMID: 34817364
Preparation and characterization of succinyl chitosan and succinyl chitosan nanoparticle film: In vitro and in vivo evaluation of wound healing activity.
Thao NTT, Wijerathna HMSM, Kumar RS, Choi D, Dananjaya SHS, Attanayake AP
Int J Biol Macromol 2021 Dec 15;193(Pt B):1823-1834. Epub 2021 Nov 13 doi: 10.1016/j.ijbiomac.2021.11.015. PMID: 34785202
Lipopolysaccharide hyporesponsiveness: protective or damaging response to the brain?
Pardon MC
Rom J Morphol Embryol 2015;56(3):903-13. PMID: 26662122
Conjugated linoleic acids: are they beneficial or detrimental to health?
Wahle KW, Heys SD, Rotondo D
Prog Lipid Res 2004 Nov;43(6):553-87. doi: 10.1016/j.plipres.2004.08.002. PMID: 15522764

Prognosis

Acute Kidney Injury and Hemolytic Anemia Secondary to Mycoplasma pneumoniae Infection.
Carrara C, Abbate M, Sabadini E, Remuzzi G
Nephron 2017;137(2):148-154. Epub 2017 Jul 7 doi: 10.1159/000478991. PMID: 28683450
Sterile pyuria in patients admitted to the hospital with infections outside of the urinary tract.
Hooker JB, Mold JW, Kumar S
J Am Board Fam Med 2014 Jan-Feb;27(1):97-103. doi: 10.3122/jabfm.2014.01.130084. PMID: 24390891
A novel DNA vaccine containing multiple TB-specific epitopes casted in a natural structure (ECANS) confers protective immunity against pulmonary mycobacterial challenge.
Gao H, Yue Y, Hu L, Xu W, Xiong S
Vaccine 2009 Aug 27;27(39):5313-9. Epub 2009 Jul 16 doi: 10.1016/j.vaccine.2009.06.093. PMID: 19615961Free PMC Article
Urine analysis performed by flow cytometry: reference range determination and comparison to morphological findings, dipstick chemistry and bacterial culture results--a multicenter study.
Regeniter A, Haenni V, Risch L, Köchli HP, Colombo JP, Frei R, Huber AR
Clin Nephrol 2001 May;55(5):384-92. PMID: 11393384
Urinalysis in the diagnosis of urinary tract infections.
Fang LS
Clin Lab Med 1988 Sep;8(3):567-76. PMID: 3048858

Clinical prediction guides

Antibacterial and Cytotoxic Study of Hybrid Films Based on Polypropylene and NiO or NiFe(2)O(4) Nanoparticles.
Rincon-Granados KL, Vázquez-Olmos AR, Rodríguez-Hernández AP, Prado-Prone G, Rivera M, Garibay-Febles V, Almanza-Arjona YC, Sato-Berrú RY, Mata-Zamora E, Silva-Bermúdez PS, Vega-Jiménez A
Int J Mol Sci 2023 Dec 2;24(23) doi: 10.3390/ijms242317052. PMID: 38069375Free PMC Article
Poly(DL-lactic acid) scaffolds as a bone targeting platform for the co-delivery of antimicrobial agents against S. aureus-C.albicans mixed biofilms.
Zegre M, Barros J, Ribeiro IAC, Santos C, Caetano LA, Gonçalves L, Monteiro FJ, Ferraz MP, Bettencourt A
Int J Pharm 2022 Jun 25;622:121832. Epub 2022 May 17 doi: 10.1016/j.ijpharm.2022.121832. PMID: 35595042
Curcumin-Loaded Bacterial Cellulose/Alginate/Gelatin as A Multifunctional Biopolymer Composite Film.
Chiaoprakobkij N, Suwanmajo T, Sanchavanakit N, Phisalaphong M
Molecules 2020 Aug 21;25(17) doi: 10.3390/molecules25173800. PMID: 32825570Free PMC Article
Lipopolysaccharide hyporesponsiveness: protective or damaging response to the brain?
Pardon MC
Rom J Morphol Embryol 2015;56(3):903-13. PMID: 26662122
Conjugated linoleic acids: are they beneficial or detrimental to health?
Wahle KW, Heys SD, Rotondo D
Prog Lipid Res 2004 Nov;43(6):553-87. doi: 10.1016/j.plipres.2004.08.002. PMID: 15522764

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