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Advanced Head and Neck Squamous Cell Carcinoma

MedGen UID:
1619962
Concept ID:
C4528408
Neoplastic Process

Definition

A head and neck squamous cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Rosenberg AJ, Vokes EE
Oncologist 2021 Jan;26(1):40-48. Epub 2020 Sep 21 doi: 10.1634/theoncologist.2020-0303. PMID: 32864799Free PMC Article
Kiyota N, Tahara M, Fujii M
Jpn J Clin Oncol 2015 Jan;45(1):2-6. Epub 2014 Nov 19 doi: 10.1093/jjco/hyu195. PMID: 25411434
Sundvall M, Karrila A, Nordberg J, Grénman R, Elenius K
Expert Opin Emerg Drugs 2010 Jun;15(2):185-201. doi: 10.1517/14728211003716442. PMID: 20415599

Recent clinical studies

Etiology

Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Patil VM, Noronha V, Menon N, Rai R, Bhattacharjee A, Singh A, Nawale K, Jogdhankar S, Tambe R, Dhumal S, Sawant R, Alone M, Karla D, Peelay Z, Pathak S, Balaji A, Kumar S, Purandare N, Agarwal A, Puranik A, Mahajan A, Janu A, Kumar Singh G, Mittal N, Yadav S, Banavali S, Prabhash K
J Clin Oncol 2023 Jan 10;41(2):222-232. Epub 2022 Oct 20 doi: 10.1200/JCO.22.01015. PMID: 36265101
Schinke H, Shi E, Lin Z, Quadt T, Kranz G, Zhou J, Wang H, Hess J, Heuer S, Belka C, Zitzelsberger H, Schumacher U, Genduso S, Riecken K, Gao Y, Wu Z, Reichel CA, Walz C, Canis M, Unger K, Baumeister P, Pan M, Gires O
Mol Cancer 2022 Sep 8;21(1):178. doi: 10.1186/s12943-022-01646-1. PMID: 36076232Free PMC Article
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Leidner R, Crittenden M, Young K, Xiao H, Wu Y, Couey MA, Patel AA, Cheng AC, Watters AL, Bifulco C, Morris G, Rushforth L, Nemeth S, Urba WJ, Gough M, Bell RB
J Immunother Cancer 2021 May;9(5) doi: 10.1136/jitc-2021-002485. PMID: 33963014Free PMC Article

Diagnosis

Worakitchanon W, Panvongsa W, Siripoon T, Kitdumrongthum S, Wongpan A, Arsa L, Trachu N, Jinawath N, Chairoungdua A, Ngamphaiboon N
JCO Precis Oncol 2023 May;7:e2300003. doi: 10.1200/PO.23.00003. PMID: 37163716
Erul E, Guven DC, Ozbay Y, Altunbulak AY, Kahvecioglu A, Ercan F, Yesil MF, Ucdal MT, Cengiz M, Yazici G, Kuscu O, Suslu N, Gullu I, Onur MR, Aksoy S
Biomark Med 2023 Jan;17(2):87-99. Epub 2023 Apr 12 doi: 10.2217/bmm-2022-0748. PMID: 37042459
Patil VM, Noronha V, Menon N, Rai R, Bhattacharjee A, Singh A, Nawale K, Jogdhankar S, Tambe R, Dhumal S, Sawant R, Alone M, Karla D, Peelay Z, Pathak S, Balaji A, Kumar S, Purandare N, Agarwal A, Puranik A, Mahajan A, Janu A, Kumar Singh G, Mittal N, Yadav S, Banavali S, Prabhash K
J Clin Oncol 2023 Jan 10;41(2):222-232. Epub 2022 Oct 20 doi: 10.1200/JCO.22.01015. PMID: 36265101
Routila J, Qiao X, Weltner J, Rantala JK, Carpén T, Hagström J, Mäkitie A, Leivo I, Ruuskanen M, Söderlund J, Rintala M, Hietanen S, Irjala H, Minn H, Westermarck J, Ventelä S
Oral Oncol 2022 Apr;127:105772. Epub 2022 Mar 1 doi: 10.1016/j.oraloncology.2022.105772. PMID: 35245886
Xu Y, Gao Z, Hu R, Wang Y, Wang Y, Su Z, Zhang X, Yang J, Mei M, Ren Y, Li M, Zhou X
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-002699. PMID: 34697216Free PMC Article

Therapy

Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Patil VM, Noronha V, Menon N, Rai R, Bhattacharjee A, Singh A, Nawale K, Jogdhankar S, Tambe R, Dhumal S, Sawant R, Alone M, Karla D, Peelay Z, Pathak S, Balaji A, Kumar S, Purandare N, Agarwal A, Puranik A, Mahajan A, Janu A, Kumar Singh G, Mittal N, Yadav S, Banavali S, Prabhash K
J Clin Oncol 2023 Jan 10;41(2):222-232. Epub 2022 Oct 20 doi: 10.1200/JCO.22.01015. PMID: 36265101
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Vos JL, Elbers JBW, Krijgsman O, Traets JJH, Qiao X, van der Leun AM, Lubeck Y, Seignette IM, Smit LA, Willems SM, van den Brekel MWM, Dirven R, Baris Karakullukcu M, Karssemakers L, Klop WMC, Lohuis PJFM, Schreuder WH, Smeele LE, van der Velden LA, Bing Tan I, Onderwater S, Jasperse B, Vogel WV, Al-Mamgani A, Keijser A, van der Noort V, Broeks A, Hooijberg E, Peeper DS, Schumacher TN, Blank CU, de Boer JP, Haanen JBAG, Zuur CL
Nat Commun 2021 Dec 22;12(1):7348. doi: 10.1038/s41467-021-26472-9. PMID: 34937871Free PMC Article
Machiels JP, Tao Y, Burtness B, Tahara M, Licitra L, Rischin D, Waldron J, Simon C, Gregoire V, Harrington K, Alves GV, Figueiredo Lima IP, Pointreau Y, M Hughes BG, Aksoy S, Hetnal M, Ge JY, Brown H, Cheng J, Bidadi B, Siu LL
Future Oncol 2020 Jun;16(18):1235-1243. Epub 2020 Jun 3 doi: 10.2217/fon-2020-0184. PMID: 32490686

Prognosis

Ren S, Lan T, Wu F, Chen S, Jiang X, Huo C, Li Z, Xie S, Wu D, Wang R, Li Y, Qiu L, Huang G, Li S, Wang X, Cen M, Cai T, Lin Z, Li J, Li B
Cancer Commun (Lond) 2023 Oct;43(10):1143-1163. Epub 2023 Sep 1 doi: 10.1002/cac2.12480. PMID: 37658605Free PMC Article
Schinke H, Shi E, Lin Z, Quadt T, Kranz G, Zhou J, Wang H, Hess J, Heuer S, Belka C, Zitzelsberger H, Schumacher U, Genduso S, Riecken K, Gao Y, Wu Z, Reichel CA, Walz C, Canis M, Unger K, Baumeister P, Pan M, Gires O
Mol Cancer 2022 Sep 8;21(1):178. doi: 10.1186/s12943-022-01646-1. PMID: 36076232Free PMC Article
Xu Y, Gao Z, Hu R, Wang Y, Wang Y, Su Z, Zhang X, Yang J, Mei M, Ren Y, Li M, Zhou X
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-002699. PMID: 34697216Free PMC Article
Magnes T, Wagner S, Kiem D, Weiss L, Rinnerthaler G, Greil R, Melchardt T
Int J Mol Sci 2021 May 7;22(9) doi: 10.3390/ijms22094981. PMID: 34067112Free PMC Article
Nwizu T, Adelstein DJ
Expert Rev Anticancer Ther 2014 Sep;14(9):1033-9. Epub 2014 Jul 6 doi: 10.1586/14737140.2014.924399. PMID: 24998393

Clinical prediction guides

Oliveira G, Egloff AM, Afeyan AB, Wolff JO, Zeng Z, Chernock RD, Zhou L, Messier C, Lizotte P, Pfaff KL, Stromhaug K, Penter L, Haddad RI, Hanna GJ, Schoenfeld JD, Goguen LA, Annino DJ, Jo V, Oppelt P, Pipkorn P, Jackson R, Puram SV, Paniello RC, Rich JT, Webb J, Zevallos JP, Mansour M, Fu J, Dunn GP, Rodig SJ, Ley J, Morris LGT, Dunn L, Paweletz CP, Kallogjeri D, Piccirillo JF, Adkins DR, Wu CJ, Uppaluri R
Sci Immunol 2023 Sep 8;8(87):eadf4968. doi: 10.1126/sciimmunol.adf4968. PMID: 37683037Free PMC Article
Ren S, Lan T, Wu F, Chen S, Jiang X, Huo C, Li Z, Xie S, Wu D, Wang R, Li Y, Qiu L, Huang G, Li S, Wang X, Cen M, Cai T, Lin Z, Li J, Li B
Cancer Commun (Lond) 2023 Oct;43(10):1143-1163. Epub 2023 Sep 1 doi: 10.1002/cac2.12480. PMID: 37658605Free PMC Article
Schinke H, Shi E, Lin Z, Quadt T, Kranz G, Zhou J, Wang H, Hess J, Heuer S, Belka C, Zitzelsberger H, Schumacher U, Genduso S, Riecken K, Gao Y, Wu Z, Reichel CA, Walz C, Canis M, Unger K, Baumeister P, Pan M, Gires O
Mol Cancer 2022 Sep 8;21(1):178. doi: 10.1186/s12943-022-01646-1. PMID: 36076232Free PMC Article
Vos JL, Elbers JBW, Krijgsman O, Traets JJH, Qiao X, van der Leun AM, Lubeck Y, Seignette IM, Smit LA, Willems SM, van den Brekel MWM, Dirven R, Baris Karakullukcu M, Karssemakers L, Klop WMC, Lohuis PJFM, Schreuder WH, Smeele LE, van der Velden LA, Bing Tan I, Onderwater S, Jasperse B, Vogel WV, Al-Mamgani A, Keijser A, van der Noort V, Broeks A, Hooijberg E, Peeper DS, Schumacher TN, Blank CU, de Boer JP, Haanen JBAG, Zuur CL
Nat Commun 2021 Dec 22;12(1):7348. doi: 10.1038/s41467-021-26472-9. PMID: 34937871Free PMC Article
Xu Y, Gao Z, Hu R, Wang Y, Wang Y, Su Z, Zhang X, Yang J, Mei M, Ren Y, Li M, Zhou X
J Immunother Cancer 2021 Oct;9(10) doi: 10.1136/jitc-2021-002699. PMID: 34697216Free PMC Article

Recent systematic reviews

Nindra U, Hurwitz J, Forstner D, Chin V, Gallagher R, Liu J
Cancer Med 2023 May;12(10):11234-11247. Epub 2023 Mar 19 doi: 10.1002/cam4.5815. PMID: 36934434Free PMC Article
Kiss F, Pohóczky K, Görbe A, Dembrovszky F, Kiss S, Hegyi P, Szakó L, Tóth L, Ezer ÉS, Szalai E, Helyes Z
Oral Dis 2023 Jul;29(5):1905-1919. Epub 2022 May 20 doi: 10.1111/odi.14228. PMID: 35485982
Bonomo P, Merlotti A, Olmetto E, Bianchi A, Desideri I, Bacigalupo A, Franco P, Franzese C, Orlandi E, Livi L, Caini S
Eur J Nucl Med Mol Imaging 2018 Nov;45(12):2122-2138. Epub 2018 Jun 9 doi: 10.1007/s00259-018-4065-5. PMID: 29948105Free PMC Article
Jacinto JK, Co J, Mejia MB, Regala EE
Br J Radiol 2017 Nov;90(1079):20170442. doi: 10.1259/bjr.20170442. PMID: 29053029Free PMC Article
Gupta T, Kannan S, Ghosh-Laskar S, Agarwal JP
Clin Oncol (R Coll Radiol) 2016 Jan;28(1):50-61. Epub 2015 Oct 9 doi: 10.1016/j.clon.2015.09.002. PMID: 26454839

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