U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Plasma Cell Myeloma by DS Stage

MedGen UID:
1620809
•Concept ID:
C4528206
•
Neoplastic Process

Definition

A header term that refers to the staging of plasma cell myeloma according to the Durie/Salmon staging system. [from NCI]

Professional guidelines

PubMed

Diagnosis and treatment of multiple myeloma in Hunan Province.
Liu F, Cheng Q, Song K, Yu H, Li J, Zhang H, Hu G, Zhou M, Wang J, Ding Z, Luo Z, Peng T, Ding L, Zhao L, Liu J, He Y, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr 28;47(4):497-504. doi: 10.11817/j.issn.1672-7347.2022.210555. PMID: 35545345
Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article

Recent clinical studies

Etiology

Diagnosis and treatment of multiple myeloma in Hunan Province.
Liu F, Cheng Q, Song K, Yu H, Li J, Zhang H, Hu G, Zhou M, Wang J, Ding Z, Luo Z, Peng T, Ding L, Zhao L, Liu J, He Y, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr 28;47(4):497-504. doi: 10.11817/j.issn.1672-7347.2022.210555. PMID: 35545345
Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): updated outcomes from a randomised, multicentre, open-label, phase 3 study.
Usmani SZ, Quach H, Mateos MV, Landgren O, Leleu X, Siegel D, Weisel K, Gavriatopoulou M, Oriol A, Rabin N, Nooka A, Qi M, Beksac M, Jakubowiak A, Ding B, Zahlten-Kumeli A, Yusuf A, Dimopoulos M
Lancet Oncol 2022 Jan;23(1):65-76. Epub 2021 Dec 3 doi: 10.1016/S1470-2045(21)00579-9. PMID: 34871550
Enrichment of circulating myeloma cells by immunomagnetic beads combined with flow cytometry for monitoring minimal residual disease and relapse in patients with multiple myeloma.
Wang N, Tesfaluul N, Li J, Gao X, Liu S, Yue B
Ann Hematol 2019 Dec;98(12):2769-2780. Epub 2019 Nov 20 doi: 10.1007/s00277-019-03833-5. PMID: 31748925
Characterizing the Tumor Suppressor Role of CEACAM1 in Multiple Myeloma.
Xu J, Liu B, Ma S, Zhang J, Ji Y, Xu L, Zhu M, Chen S, Wu X, Wu D
Cell Physiol Biochem 2018;45(4):1631-1640. Epub 2018 Feb 21 doi: 10.1159/000487730. PMID: 29486474
Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article

Diagnosis

Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma.
Ma NY, Li Q, Li XL, Zeng YJ, Huang DZ, Duan YS, Xia J, Liu BD, Rao LY, Rao J, Zhang X
Curr Med Sci 2023 Aug;43(4):679-688. Epub 2023 Jun 16 doi: 10.1007/s11596-023-2747-0. PMID: 37326888
LAMP5 may promote MM progression by activating p38.
Chen Y, Ma T
Pathol Oncol Res 2023;29:1611083. Epub 2023 Mar 22 doi: 10.3389/pore.2023.1611083. PMID: 37033323Free PMC Article
Diagnosis and treatment of multiple myeloma in Hunan Province.
Liu F, Cheng Q, Song K, Yu H, Li J, Zhang H, Hu G, Zhou M, Wang J, Ding Z, Luo Z, Peng T, Ding L, Zhao L, Liu J, He Y, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr 28;47(4):497-504. doi: 10.11817/j.issn.1672-7347.2022.210555. PMID: 35545345
Characterizing the Tumor Suppressor Role of CEACAM1 in Multiple Myeloma.
Xu J, Liu B, Ma S, Zhang J, Ji Y, Xu L, Zhu M, Chen S, Wu X, Wu D
Cell Physiol Biochem 2018;45(4):1631-1640. Epub 2018 Feb 21 doi: 10.1159/000487730. PMID: 29486474
Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article

Therapy

Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma.
Ma NY, Li Q, Li XL, Zeng YJ, Huang DZ, Duan YS, Xia J, Liu BD, Rao LY, Rao J, Zhang X
Curr Med Sci 2023 Aug;43(4):679-688. Epub 2023 Jun 16 doi: 10.1007/s11596-023-2747-0. PMID: 37326888
Diagnosis and treatment of multiple myeloma in Hunan Province.
Liu F, Cheng Q, Song K, Yu H, Li J, Zhang H, Hu G, Zhou M, Wang J, Ding Z, Luo Z, Peng T, Ding L, Zhao L, Liu J, He Y, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr 28;47(4):497-504. doi: 10.11817/j.issn.1672-7347.2022.210555. PMID: 35545345
Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): updated outcomes from a randomised, multicentre, open-label, phase 3 study.
Usmani SZ, Quach H, Mateos MV, Landgren O, Leleu X, Siegel D, Weisel K, Gavriatopoulou M, Oriol A, Rabin N, Nooka A, Qi M, Beksac M, Jakubowiak A, Ding B, Zahlten-Kumeli A, Yusuf A, Dimopoulos M
Lancet Oncol 2022 Jan;23(1):65-76. Epub 2021 Dec 3 doi: 10.1016/S1470-2045(21)00579-9. PMID: 34871550
Enrichment of circulating myeloma cells by immunomagnetic beads combined with flow cytometry for monitoring minimal residual disease and relapse in patients with multiple myeloma.
Wang N, Tesfaluul N, Li J, Gao X, Liu S, Yue B
Ann Hematol 2019 Dec;98(12):2769-2780. Epub 2019 Nov 20 doi: 10.1007/s00277-019-03833-5. PMID: 31748925
Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article

Prognosis

Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma.
Ma NY, Li Q, Li XL, Zeng YJ, Huang DZ, Duan YS, Xia J, Liu BD, Rao LY, Rao J, Zhang X
Curr Med Sci 2023 Aug;43(4):679-688. Epub 2023 Jun 16 doi: 10.1007/s11596-023-2747-0. PMID: 37326888
LAMP5 may promote MM progression by activating p38.
Chen Y, Ma T
Pathol Oncol Res 2023;29:1611083. Epub 2023 Mar 22 doi: 10.3389/pore.2023.1611083. PMID: 37033323Free PMC Article
Diagnosis and treatment of multiple myeloma in Hunan Province.
Liu F, Cheng Q, Song K, Yu H, Li J, Zhang H, Hu G, Zhou M, Wang J, Ding Z, Luo Z, Peng T, Ding L, Zhao L, Liu J, He Y, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr 28;47(4):497-504. doi: 10.11817/j.issn.1672-7347.2022.210555. PMID: 35545345
CDK5 inhibition in vitro and in vivo induces cell death in myeloma and overcomes the obstacle of bortezomib resistance.
Tang H, Xu L, Cen X, Yang L, Feng J, Li G, Zhu H, Gao S, Yu Y, Zhao Y, Tian Z, Hou L, Yu S, Gao G
Int J Mol Med 2020 Jun;45(6):1661-1672. Epub 2020 Mar 26 doi: 10.3892/ijmm.2020.4553. PMID: 32236619Free PMC Article
High Expression Levels of Long Noncoding RNA Small Nucleolar RNA Host Gene 18 and Semaphorin 5A Indicate Poor Prognosis in Multiple Myeloma.
Huang LJ, Shen Y, Bai J, Wang FX, Feng YD, Chen HL, Peng Y, Zhang R, Li FM, Zhang PH, Lei XR, Xue F, Ma YP, Hu JS, He AL
Acta Haematol 2020;143(3):279-288. Epub 2019 Oct 9 doi: 10.1159/000502404. PMID: 31597158

Clinical prediction guides

Comprehensive analysis and establishment of a prognostic model based on non-genetic predictors in multiple myeloma.
Lu W, Xu S, Tan S, Lu L, Luo M, Xiao M
Cancer Biomark 2023;38(1):49-59. doi: 10.3233/CBM-220451. PMID: 37522196Free PMC Article
Lactate Decreases Bortezomib Sensitivity and Predicts Poor Clinical Outcomes of Multiple Myeloma.
Ma NY, Li Q, Li XL, Zeng YJ, Huang DZ, Duan YS, Xia J, Liu BD, Rao LY, Rao J, Zhang X
Curr Med Sci 2023 Aug;43(4):679-688. Epub 2023 Jun 16 doi: 10.1007/s11596-023-2747-0. PMID: 37326888
NUPR1 Silencing Induces Autophagy-Mediated Apoptosis in Multiple Myeloma Cells Through the PI3K/AKT/mTOR Pathway.
Li A, Li X, Chen X, Zeng C, Wang Z, Li Z, Chen J
DNA Cell Biol 2020 Mar;39(3):368-378. Epub 2020 Jan 22 doi: 10.1089/dna.2019.5196. PMID: 31971825
Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article
Multiple myeloma in elderly patients: presenting features and outcome.
Rodon P, Linassier C, Gauvain JB, Benboubker L, Goupille P, Maigre M, Luthier F, Dugay J, Lucas V, Colombat P
Eur J Haematol 2001 Jan;66(1):11-7. doi: 10.1034/j.1600-0609.2001.00301.x. PMID: 11168502

Recent systematic reviews

Early versus deferred treatment for early stage multiple myeloma.
He Y, Wheatley K, Clark O, Glasmacher A, Ross H, Djulbegovic B
Cochrane Database Syst Rev 2003;2003(1):CD004023. doi: 10.1002/14651858.CD004023. PMID: 12535504Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...